Clinical trials: Alveolar; Wound
Acute Lung Injury
Omics Sequencing of Exosomes in Body Fluids of Patients With Acute Lung Injury
The exosomes in the experimental group and the control group were sequenced to find the difference of the two groups, providing a basis for subsequent basic research.
- Trial name
- NCT05058768
- Testing
- The lungs causes and extrapulmonary factors
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Pain, Infection
Safety of Coronectomy vs Excision of Wisdom Teeth
The purpose of this study is to compare the surgical complications and neurosensory disturbance of coronectomy and conventional excision of wisdom teeth with roots in close proximity to inferior alveolar nerve.
- Conditions
- Pain, Infection, Alveolar Nerve Injury
- Trial name
- coronrct (NCT00752284)
- Testing
- Coronectomy, Total Excision
- Where
- China
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Soft Tissue, Dental Implants
Xenogenic Bone Intentionally Left Exposed
The goal of this clinical trial is to compare, the effect of letting the xenogeneic bone graft exposed to the oral environment or seal off the graft with a collagen matrix.
- Conditions
- Soft Tissue, Dental Implants, Healing Wound
- Trial name
- NCT06191510
- Testing
- Bio-Oss Exposed, Mucograft Exposed
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Tooth Extraction, Periapical Infections
Cortical Lamina for Alveolar Ridge Preservation
This randomized controlled clinical trial aims to evaluate the efficacy of placing a cortical lamina between the elevated flap and buccal bone plate following tooth extraction for preserving alveolar ridge dimensions.
- Conditions
- Tooth Extraction, Periapical Infections, Tooth Fracture, Periodontal Disease, AVDC Stage 4
- Trial name
- Lamina (NCT07231874)
- Testing
- Cortical Lamina Technique, Natural Healing (Control)
- Where
- Cuba
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Alveolar Bone Resorption, Graft Overgrowth
Histological and Volumetric Evaluation of Customized Allograft Bone Blocks
Customized bone blocks need CBCT and digital software to design the block needed to rehabilitate. Some advantages are reduced surgical time and better adaptation of the graft, leading to less complications.
- Conditions
- Alveolar Bone Resorption, Graft Overgrowth, Resorption of Bone Graft, Graft Complication
- Trial name
- NCT05937035
- Testing
- Customized allogenic bone block surgery
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Mandibular Nerve Injury
Study on the Risk of Inferior Alveolar Nerve Damage During Lower Third Molar Surgery
Objective The present study aimed to evaluate which factors were statistically associated with a greater probability of inferior alveolar nerve (IAN) damage during lower third molar surgery.
- Trial name
- NCT04807946
- Testing
- lower third molar extraction
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Tooth Fractures, Tooth Extraction Status Nos
Alveolar Ridge Preservation Following Tooth Extraction.
Bone resorption after a tooth extraction is a generally accepted knowledge and has been demonstrated by many animal and human studies.
- Conditions
- Tooth Fractures, Tooth Extraction Status Nos, Caries
- Trial name
- NCT05505084
- Testing
- Tooth extraction and ridge preservation using different barrier mermbranes
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Extraction, Tooth, Tooth Fracture
Platelet-Rich Fibrin (PRF) vs Bone Graft With Membrane for Ridge Preservation After Tooth Extraction
This study uses a natural material called Platelet-Rich Fibrin (PRF) to help improve healing after tooth removal. PRF is made from your own blood.
- Conditions
- Extraction, Tooth, Tooth Fracture, Tooth Crown Fracture, Root; Fracture
- Trial name
- NCT07595198
- Testing
- Platelet-rich fibrin (PRF), Freeze-dried bone allograft, Collagen barrier membrane
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Bone Loss, Implant Site Injury
Tunnel Access for Lateral Alveolar Ridge Augmentation
Minimally invasive procedures with the tunnel technique have been suggested to decrease patient post-operative discomfort and morbidity in oral bone regeneration.
- Trial name
- NCT05475730
- Testing
- bone and soft tissue augmentation
- Where
- Italy
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- D'Albis Dental
Healing Wound, Alveolar; Wound
Ultrasound for Socket Healing Evaluation
The design is a single blinded, dual comparative study of ultrasound versus micro-CT/LASCA in one study group. Up to a total of 140 subjects registered will be recruited.
- Conditions
- Healing Wound, Alveolar; Wound, Alveolar Bone Loss, Image
- Trial name
- NCT06017193
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Tooth Injuries, Tooth Abnormalities
Vertical Augmentation With Osteon at Dental Implant Placement
Dental implants are a valid and reliable method to replace missing teeth. The major requirement for their success is an adequate volume of bone into which they can be placed.
- Trial name
- NCT01162629
- Testing
- Osteon bone graft
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Research and Education in Dentistry
Acute Lung Injury
Changes in Alveolar Macrophage Function During Acute Lung Injury
In this study, the investigators aim to observe the change in alveolar macrophage function during acute lung injury.
- Trial name
- NCT02693912
- Testing
- Bronchoscopy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Dental Implant Failed
Digital Assessment at Peri-implant Tissues After Immediate Implants With Customized Healing Abutments and Connective Tissue Grafts
After a single-tooth extraction, physiological remodeling processes are unavoidable which leads to a total loss of the periodontal ligament and resorption of the bundle bone.
- Trial name
- NCT05060055
- Testing
- Immediate dental implant placement
- Where
- Portugal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidade Católica Portuguesa
Smoking, Cigarette, Alveolar Bone Grafting
Wound Healing Following Extraction and Ridge Preservation in Smokers and Non-smokers
The goal of this study is to evaluate bone wound healing following extraction and alveolar ridge preservation (bone graft and membrane) clinically, histologically and in relation to gene expression in smokers and non-smokers.
- Conditions
- Smoking, Cigarette, Alveolar Bone Grafting, Wound Healing, Bone Healing
- Trial name
- NCT07372183
- Testing
- observational study
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Marquette University
Distraction of Bone, Dental Implant
Osteogenic Potential of Cissus Quadrangularis Alveolar Ridge Distraction
Deficient alveolar mandibular ridge corrected distraction osteogenesis to facilitate dental implant placement. Patients grouped into 2 groups: one group received Cissus quadrangularis during the consolidation period, and the…
- Trial name
- NCT04669795
- Testing
- Cissus Quadrangularis
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Alveolar Bone Resorption, Wound Heal
Alveolar Socket Healing With and Without PRGF
A single-centre randomised controlled pilot study involving 12-24 healthy adult patients for investigating dental extraction socket healing with and without plasma rich in growth factors (PRGF) taking place during early days of…
- Trial name
- NCT04383158
- Testing
- PRGF ENDORET® obtained from ENDORET® POST-EXTRACTION ALVEOLUS DENTAL KIT (KMU16)
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Impacted Mandibular Third Molar, Wound Healing
Adjacent Molar Outcomes After Third Molar Surgery With PRF or Collagen Sponge
This study aims to compare platelet-rich fibrin (PRF) and an absorbable collagen sponge in extraction sockets following impacted mandibular third molar removal in terms of postoperative clinical healing and periodontal and…
- Conditions
- Impacted Mandibular Third Molar, Wound Healing, Postoperative Pain
- Trial name
- PRFvsCOLL-3M (NCT07530068)
- Testing
- Platelet-rich fibrin (PRF), Absorbable Collagen Sponge
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Gazi University
Ventilator-Induced Lung Injury, Positive End-Expiratory Pressure
A Central and Eastern European Survey On PEEP Titration and Alveolar Recruitment Manoeuvres During Surgery
The aim of this questionnaire-based survey is to evaluate the routine use of individual positive end-expiratory pressure (PEEP) and regular alveolar recruitment manoeuvres (ARM) of Central and Eastern European anaesthesiologists…
- Conditions
- Ventilator-Induced Lung Injury, Positive End-Expiratory Pressure, Alveolar Recruitment Manoeuvres
- Trial name
- NCT04030078
- Testing
- Survey
- Where
- Hungary
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Péterfy Sándor Hospital
Alveolar Process Atrophy, Smoking, Cigarette
Platelet Rich Fibrin Treatment for the Alveolar Ridge Preservation in Smokers
Bone healing is affected by smoking, particularly healing of extraction sockets, showing deficiencies in vertical and horizontal bone dimensions compared to the healing of non-smokers.
- Conditions
- Alveolar Process Atrophy, Smoking, Cigarette, Platelet-Rich Fibrin
- Trial name
- NCT06190860
- Testing
- Autologous Leukocyte and platelet-rich fibrin, Intraoral Scan, Computed Tomography
- Where
- 2 sites in Chile
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Wound Heal
Effect of A-PRF After Removal of Wisdom Teeth
To evaluate the healing effect of advanced platelet-rich fibrin (blood clot charged with growth factors) taken from the patient own blood on the extraction site.
- Trial name
- A-PRF (NCT03703479)
- Testing
- autologous blood clot made from the patient own clot without any additive
- Where
- Saudi Arabia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University