Clinical trials: Alveolar Bone Resorption
Horizontal Alveolar Bone Defect, Alveolar Bone Loss
Evaluation of Mineralized Plasmatic Matrix With and Without Collagen Membrane in Peri-implant Bone Regeneration
This study focuses on comparing the effect of MPM with or without collagen membrane on delayed implant placement in anterior maxillary aesthetic zone.
- Trial name
- NCT04816110
- Testing
- mineralized plasmatic matrix with collagen membrane, mineralized plasmatic matrix (MPM) without collagen membrane
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Alexandria University
Bone Loss, Alveolar, Dental Implant Failure Nos
Implant/Abutment Module Stability of Original vs Compatible Connections
Together with materials and type of retention, the stability of the implant abutment connection represents one of the key factor for the success rate of an implant supported restoration.
- Trial name
- NCT03524872
- Testing
- Original CAD/CAM prosthetic abutment, Compatible CAD/CAM abutment, Local anesthesia
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Edentulism, Alveolar Bone Atrophy
The Influence of Dimensional Anatomic Variables on the Outcomes of Maxillary Sinus Grafting Procedures
The hypothesis of this study is that there is a significant difference in bone maturation after sinus grafting determined by the distance from the buccal to the palatal wall of this cavity.
- Conditions
- Edentulism, Alveolar Bone Atrophy, Sinus Pneumatization
- Trial name
- NCT00868777
- Testing
- Sinus grafting using allogenic bone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Michigan
Alveolar Bone Resorption, Alveolar Ridge Enlargement
Is Cross-linked Hyaluronic Acid a Biologic Alternative for Alveolar Ridge Preservation?
Even after atraumatic tooth removal and/or immediate implant placement, some reduction of the alveolar ridge dimension is expected.
- Conditions
- Alveolar Bone Resorption, Alveolar Ridge Enlargement, Tooth Extraction, Hyaluronic Acid
- Trial name
- NCT07496437
- Testing
- DBBM + FGG, Hyaluronic acid + collagen sponge + FGG
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Alveolar Bone Loss, Maxillary Sinus Bone Loss
Anti-HLA Antibodies After Bone Regeneration Surgery
This study evaluates the occurrence of anti-human leukocyte antigen (anti-HLA) antibodies following bone regeneration procedures performed prior to dental implant therapy.
- Trial name
- Anti-HLA Bone (NCT07474857)
- Testing
- Xenogeneic Bone Graft, Allogeneic Bone Graft, Low-Level Laser Therapy
- Where
- Poland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical Innovation Center Wroclaw
Alveolar Bone Resorption
Lateral Ridge Augmentation Around Implants
The rehabilitation of dentoalveolar defects and tooth loss has seen remarkable advancements over time. Extraction of tooth leads to reduction in physiologic dimension of bone and it is imperative to evaluate the site before…
- Trial name
- NCT04197128
- Testing
- Resorbable Collagen membrane with bone graft for augmentation, Ribose cross linked collagen matrix for augmentation
- Where
- India
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Alveolar Bone Loss
Effect of Topical Melatonin Application on Dental Implant Osseointegration and Marginal Bone Level
Background: Melatonin (N-acetyl-5-methoxy-tryptamine) is an indoleamine synthesized and secreted by the pineal gland and other organs, such as the retina, bone marrow, and intestines in a circadian pattern.
- Trial name
- NCT04229719
- Testing
- N-acetyl-5-methoxytryptamine
- Where
- Iraq
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Alveolar Bone Loss, Edentulous Maxilla, Atrophic
Guided Bone Regeneration Combined With PRGF for Atrophic Edentulous Maxilla
This prospective interventional clinical study evaluated guided bone regeneration combined with plasma rich in growth factors for vertical and horizontal augmentation of the atrophic edentulous maxilla.
- Conditions
- Alveolar Bone Loss, Edentulous Maxilla, Atrophic, Alveolar Ridge Deficiency, Jaw Atrophy
- Trial name
- GBR-PRGF-Maxil (NCT07654218)
- Testing
- Guided Bone Regeneration Combined With Plasma Rich in Growth Factors
- Where
- Portugal
- Volunteers
- 11 people
- Sponsor
- Universidade do Porto
Periodontal Diseases, Periodontal Bone Loss
Adjunctive Antioxidant Effect of Centella Asiatica Nanoemulsion Gel in Management of Periodontitis
The aims of the current study are: 1. Evaluation of the clinical efficacy of local delivery of nanoemulsion gel containing Centella asiatica extract as an adjunct to conventional non-surgical periodontal therapy in periodontitis…
- Trial name
- NCT07697209
- Testing
- Centella asiatica nanoemulsion gel, Scaling and Root Planing (SRP)
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Alveolar Bone Loss
A Clinical Investigation to Evaluate the Healing of Tooth Extraction Sites Filled With BioRestore™
The aim of this study was to evaluate by histology and MSCT scans during a 7-month period, the efficacy of a bioactive glass (Inion BioRestore™) placed in human extraction sockets in the maintenance of alveolar ridge.
- Trial name
- NCT01105026
- Testing
- Alveolar Bone Defect Regeneration Following Tooth Extraction
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Alveolar Bone Loss
Effectiveness in Limiting the Need to Elevate the Maxillary Sinus
The aim of the present study is to evaluate the effectiveness of different alveolar preservation procedures performed at the time of extraction of the first or second upper molar in avoiding a maxillary sinus elevation or at…
- Trial name
- SO-GHI (NCT03357705)
- Testing
- alveolar ridge preservation with synthetic bone, alveolar ridge preservation with bovine collagen
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Periodontal Bone Loss
Effect of Enamel Matrix Proteins on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients
The purpose of the study is to determine the effect of enamel matrix protein derivative on an inflamed, periodontal-involved tooth.
- Trial name
- NCT02972788
- Testing
- Enamel Matrix Proteins Derivative, Saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Nebraska
Alveolar Bone Loss, Bone Graft Failure
Ridge Preservation In Mandibular Molars Using Mixture Of ABB And Autogenous Particulate VS Sticky Bone
Histological Measurement Comparing the density of the new bone formed during socket preservation technique using a Mixture of Anorganic Bovine Bone(ABB) And Autogenous Particulate vs a Mixture of Injectable Platelets Rich Fibers…
- Conditions
- Alveolar Bone Loss, Bone Graft Failure, Alveolar Bone Resorption
- Trial name
- NCT03584997
- Testing
- ABB And Autogenous Particulate, PRF, ABB & Autogenous Particulate
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Ridge Augmentation, Bone Substitutes
Alveolar Ridge Preservation (ARP) Study Using Alloplastic Biomaterial and a Resorbable Synthetic Membrane. A Digital Workflow (CBCT/Scanner) Evaluates Hard and Soft Tissue Volumetric Changes at 4 Months, Validating Support for the Gingival Phenotype and Buccal Bone Plate.
The dimensional collapse of the alveolar ridge following tooth extraction represents a critical challenge for implant rehabilitation.
- Conditions
- Alveolar Ridge Augmentation, Bone Substitutes, Guided Tissue Regeneration, Periodontal, Cone-Beam Computed Tomography
- Trial name
- NCT07879495
- Testing
- Alveolar Ridge Preservation using a synthetic alloplastic bone substitute and a resorbable polymer membrane, Minimally invasive flapless tooth extraction followed by unassisted spontaneous healing
- Volunteers
- 28 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Crowding of Anterior Maxillary Teeth, Crowding of Anterior Mandibular Teeth
Comparing Labial and Lingual Orthodontic Appliances on Root Resorption and Bone Height
Patients who have moderate crowding that could be treated on a non-extraction will be treated in this study. The apical root resorption and alveolar bone height of the lingual and labial fixed appliances will be assessed.
- Trial name
- NCT06401369
- Testing
- Lingual brackets, Buccal brackets
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Alveolar Bone Loss
Comparison of Extra-short (4 mm) Implants Used as Distal Support of a Maxillary Full-arch Fixed Dental Prosthesis vs. 10 mm Implants Installed After Sinus Floor Elevation.
Recently, 4 mm long implants with a standard diameter have been used for the restoration of the posterior edentulous mandible with favorable results.
- Trial name
- NCT03958448
- Testing
- Placement of extra short implants, maxillary sinus lift, maxillary sinus elevation, maxillary sinus augmentation, placement of standard implant
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Alveolar Bone Resorption, Sequela
Bone Material Comparison in Maxillary Sinus Augmentation
Hard and soft tissue deficiencies of an alveolar ridge arise as sequelae of tooth extraction when socket preservation is not applied.
- Conditions
- Alveolar Bone Resorption, Sequela, Tooth Extrusion
- Trial name
- NCT04433117
- Testing
- Shefabone, Bio-Oss
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mohanad Al-Sabbagh
Edentulous Posterior Maxilla, Maxillary Sinus Pneumatization
Graftless TSFE Via Self-tapping Implants
This prospective clinical trial aims to evaluate the efficiency, safety, and reliability of a minimally invasive graftless transcrestal sinus lifting approach with simultaneous dental implant placement in patients with edentulous…
- Conditions
- Edentulous Posterior Maxilla, Maxillary Sinus Pneumatization, Alveolar Bone Atrophy
- Trial name
- G-TSFE (NCT07424742)
- Testing
- Graftless Transcrestal Sinus Membrane Elevation with Simultaneous Implant Placement
- Where
- Yemen
- Volunteers
- 20 people
- Sponsor
- Sana'a University
Alveolar Process Atrophy
Ridge Preservation With Provisional Ovoid Pontic
A prospective randomized controlled trial of 30 patients from the Faculty of Dentistry of the UFJF was conducted. It was included patients who presented indication of extraction of premolars, canines or incisors.
- Trial name
- NCT03166475
- Testing
- Surgical procedures
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Juiz de Fora
Alveolar Cleft
Partial Maxillary Expansion With Post Grafting Expansion vs. Pre Full Maxillary Expansion in Secondary Alveolar Cleft
Intermediate grafting with both pre- and post- grafting maxillary expansion with time span after grafting 6-8 weeks for consolidation and final retention for 3 months after finalization of expansion will get the advantages of…
- Trial name
- NCT05941988
- Testing
- pre grafting partial maxillary expansion with post grafting expansion
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University