Clinical trials: Alveolar Process Atrophy
Alveolar Bone Loss, Alveolar Ridge Augmentation
A Novel Approach for Horizontal Augmentation: A Split Box
The goal of this clinical study is to investigate the effectiveness of the split-box technique in systemically healthy, non-smoking, over 18 years of age, participants with narrow crests (<5mm bone width) and adequate bone height…
- Conditions
- Alveolar Bone Loss, Alveolar Ridge Augmentation, Augmentation, Alveolar Ridge
- Trial name
- NCT06177899
- Testing
- Splitting of bone and fixation of bone laminae differ between the 3 groups.
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Marmara University
Bone Resorption, Alveolar Bone Loss
Autogenous Bone Mixed With Xenograft Versus Xenograft Alone Versus Absorbent Gelatin Sponge
Alveolar bone atrophy post-extraction has been well documented in the past years. normal healing event results in a minimal loss of vertical height (around 1 mm), but a substantial loss of width in the buccal-lingual plane (4-6…
- Conditions
- Bone Resorption, Alveolar Bone Loss, Alveolar Bone Resorption, Bone Graft Failure
- Trial name
- NCT03584984
- Testing
- Mixture of Autogenous bone & Anorganic Bovine Bone (ABB), Anorganic Bovine Bone (ABB), Absorbable gelatin sponge
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ridge Preservation, Alveolar Bone Loss
Evaluation of Autogenous Demineralized Dentin Graft for Ridge Preservation With and Without Injectable Platelet Rich Fibrin
Ridge preservation should be considered whenever possible after tooth extraction. Whether implant placement would be performed or for aesthetic consideration at pontic sites when conventional bridge is planned.
- Conditions
- Ridge Preservation, Alveolar Bone Loss, Dentin Graft
- Trial name
- NCT05437172
- Testing
- injectable platelet rich fibrin with demineralized dentin graft, demineralized dentin graft
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Bone Loss, Periodontal Pocket
Locally Injected Vit D as a Non-surgical Modality for Periodontal Regeneration of Infrabony Defects
vitamin D has great role in bone regenration and soft tissue health. in the past periodontal regeneration was performed using bone graft and barrier membrane
- Trial name
- NCT03716765
- Testing
- locally injected vitamin D
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bone Loss, Alveolar, Dental Implant Failed
Clinical and Radiographic Evaluation of Bone and Tissue Level Single Unit Implants: Two-piece Abutment Concept
Dental implants have become one of the most common treatments used for the rehabilitation of lost teeth. The success rate of dental implant treatment is quite high.
- Trial name
- NCT05592821
- Testing
- dental implant placement
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Berceste Guler
Periodontitis, Diabetes Mellitus, Type 2
A Danish Nationwide Longitudinal Study on Prevalence of Periodontitis and Its Co-morbidities
The project (PlanPerioMed) is a register-based study evaluating the associations and patterns of health care delivery between periodontitis and medical diseases using data from the Danish dental record system Dentalsuite…
- Conditions
- Periodontitis, Diabetes Mellitus, Type 2, Cardiovascular Diseases, Rheumatoid Arthritis
- Trial name
- PlanPerioMed (NCT05574231)
- Testing
- Periodontal treatment
- Volunteers
- 4,000,000 people
- Sponsor
- University of Copenhagen
Alveolar Bone Loss* / Therapy
Study on Silk Fibroin-Reinforced Collagen-Based Composite Membrane for Periodontal Bone Tissue Regeneration
Based on the mechanism of intramembranous ossification of the alveolar bone, it is necessary to design a biomimetic membrane material based on the principle of GBR (Guided Bone Regeneration) to simulate the biological…
- Trial name
- NCT07574853
- Testing
- Silk Fibroin-Reinforced Collagen-Based Composite Membrane
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Alveolar Bone Loss
Autogenous Demineralized Dentin Block Graft Versus Particulate Deproteinized Bovine Bone Graft for Alveolar Ridge Preservation
The aim of this trial is to compare the effect of autogenous demineralized dentin block graft (ADDBG) versus particulate deproteinized bovine bone graft (PDBBG) on alveolar ridge preservation after extraction of non-restorable…
- Trial name
- NCT05374083
- Testing
- Alveolar ridge preservation using autogenous demineralized dentin block graft, Alveolar ridge preservation using particulate deproteinized bovine bone graft
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss, Tooth Loss / Rehabilitation
Bone and Soft Tissue Healing After Socket Preservation With NOVAMag or Permamem Membranes
After tooth extraction, the surrounding bone and soft tissue may undergo dimensional reduction. Socket preservation involves placement of a bone graft into the extraction socket and coverage with a membrane to support healing…
- Conditions
- Alveolar Bone Loss, Tooth Loss / Rehabilitation, Alveolar Bone Grafting, Socket Preservation
- Trial name
- NCT07856693
- Testing
- NOVAMag Membrane, permamem Membrane, Alveolar Socket Preservation With an Allogeneic Bone Graft
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Alveolar Bone Loss
Clinical Trial on the Safety and Efficacy of Magnesium Doped Calcium Silicate 3d Alveolar Bone Repair Unit for Periodontal Bone Defects
The goal of this clinical trial is to test in height increment of alveolar bone and safety evaluation index. The main question it aims to answer are: The safety and effectiveness of magnesium calcium silicate three-dimensional…
- Trial name
- NCT05743452
- Testing
- GBR with CS@Mg
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Alveolar Bone Loss, Alveolar Ridge Augmentation
Evaluation of Guided Tissue Regeneration With Autogenous Bone Chips and CGF During Implant Placement
CGF membranes will be prepared using a swing-lock centrifuge. A full-thickness mucoperiosteal flap will be elevated in a narrow alveolar ridge. Implants will be inserted.
- Conditions
- Alveolar Bone Loss, Alveolar Ridge Augmentation, Dental Implant
- Trial name
- CGF (NCT07521514)
- Testing
- concentrated growth factor (CGF) Membrane
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Cairo University
Bleeding on Probing, Alveolar Bone Loss
Single vs. Two Implants for Mandibular Overdentures
This study aimed to compare the use of single implants in the symphyseal and parasymphyseal, and two implants were inserted in the canine area bilaterally to assist mandibular complete overdentures regarding clinical evaluation…
- Conditions
- Bleeding on Probing, Alveolar Bone Loss, Mastication, Dental Plaque
- Trial name
- SIMO/TIMO (NCT06599450)
- Testing
- Root form dental implant
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Al-Azhar University
Alveolar Process Atrophy
Evaluation of a Combined Ridge Expansion Technique With Simultaneous Dental Implant Placement
Patients with long span, narrow edentulous ridge in the posterior mandible underwent piezotomed ridge splitting and osseodensification with simultaneous implant placement.
- Trial name
- NCT05685576
- Testing
- Piezotomed ridge splitting and osseodensification
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Lydia Nabil
Tooth Loss in the Anterior Maxilla, Alveolar Bone Loss* / Therapy
Beta-Tricalcium Phosphate Grafting of Peri-implant Jumping Gaps Greater Than 2 mm in Immediate Implants
This randomized controlled trial evaluated whether grafting the peri-implant "jumping gap" with injectable β-tricalcium phosphate (β-TCP) improves outcomes after immediate implant placement in sites where the horizontal gap…
- Trial name
- NCT07709676
- Testing
- Experimental: Test: beta-tricalcium phosphate grafting
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Minia University
Alveolar Bone Loss
Use of Hyaluronic Acid as a Therapeutic Strategy for Bone Repair in Human
The aim of this study is to evaluate the effects of hyaluronic acid (HA) on bone healing in human dental sockets.
- Trial name
- NCT02709525
- Testing
- hyaluronic acid
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Alveolar Bone Loss
Demineralized Whole-tooth vs Demineralized Particulate Dentin Grafts in Alveolar Ridge Preservation
The aim of this trial is to compare whole-tooth vs particulate dentin for their effects in alveolar ridge preservation.
- Trial name
- NCT05336149
- Testing
- Alveolar ridge preservation using whole-tooth dentin graft, Alveolar ridge preservation using particulate dentin graft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Periodontitis, Periodontal Bone Loss
Use of the xCELLigence System for Quantification of Bacterial Biofilm's Real Time Formation and Antibiotics Selection.
The aim of the study is to develop an in vitro model of growth of oral biofilms, and validate xCELLigence system for the selection of an effective antibiotic treatment for each patient.
- Conditions
- Chronic Periodontitis, Periodontal Bone Loss, Resistance Bacterial
- Trial name
- NCT03863249
- Testing
- SCALE AND ROOT PLANING, ADJUNTIVE ANTIBIOTICS, MICROBIAL SAMPLING
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- University of Valencia
Alveolar Bone Loss
Lamina Soft With Different Collagen Based Materials in Bone Regeneration
This prospective controlled clinical pilot study will compare the effectiveness of two different grafting strategies for horizontal bone regeneration in healed post-extraction sites with buccal bone deficiency, using a…
- Trial name
- NCT07572643
- Testing
- Guided Bone Regeneration with Implant Placement, Collagenated Xenogeneic Bone Graft, Hydroxyapatite Xenograft with Autologous Bone
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Nicola Alberto Valente, DDS, MS, PhD
Vertical Alveolar Bone Loss
Initial Clinical and CBCT Outcomes of Enamel Matrix Derivative-Based Regenerative Therapy in Vertical Bone Defects
Study of the effectiveness of the application of regenerative therapy with autogenous, platelet-rich plasma in vertical defects Investigation of the effectiveness of the application of regenerative therapy with enamel matrix…
- Trial name
- NCT06639555
- Testing
- PRP( platelet rich plasma), EMD (Enamel Matrix Derivative), Guided Tissue Regeneration (barrier membrane)
- Where
- Bulgaria
- Volunteers
- 48 people
- Sponsor
- Tsvetalina Gerova-Vatsova
Vertical Alveolar Bone Loss
Clinical Evaluation of RTX Locator Attachments for Implant-supported Mandibular Complete Overdenture
This study was conducted to clinically and radiographically evaluate locator RTx attachments for two implant-supported mandibular overdenture using two loading protocols
- Trial name
- NCT05290376
- Testing
- surgical placement of long dental implants, overdenture supported by RTX attachment system
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University