Clinical trials: Amblyopia
Anisometropic Amblyopia, Accommodation Disorder
Accommodation Response in Hypermetropic Anisometropia (ARIHA Study)
Anisometropic amblyopia is when one eye has a much stronger glasses prescription than the other, causing poor vision in one eye, even with glasses, because the brain favours the better-seeing eye.
- Trial name
- ARIHA (NCT06286410)
- Testing
- Bespoke glasses prescription worn during amblyopia treatment.
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Amblyopia, Strabismus
Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner
The purpose of this project is to compare the performance of the Pediatric Vision Scanner (PVS) with the Gold Standard Examination to determine the effectiveness of the PVS at detecting amblyopia and strabismus.
- Trial name
- NCT01832883
- Testing
- Pediatric Vision Scanner
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Amblyopia, Anisometropia
Enhanced Housing Photoscreeners 2WIN and GoCheckKids Compared in Burma and Alaska
"Adaptica" (Padova, Italy) designed a fixed-distance, dark portable tube with power and remote control for the "2WIN: photoscreener.
- Trial name
- NCT04068129
- Testing
- photoscreen
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Alaska Blind Child Discovery
Amblyopia
Early Detection and Prevention of Amblyopia and Visual Impairment Through Systematic Pediatric Vision Screening
Amblyopia, characterized by reduced visual acuity, develops in childhood due to insufficient sensory stimulation of the affected eye.
- Trial name
- FALSSE (NCT07112560)
- Testing
- Standard screening procedure for amblyopia, New amblyopia screening method using a virtual reality headset.
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Amblyopia
Clinical Treatment of Transcranial Direct Current Stimulation in Older Adolescents With Amblyopia
As a neurodevelopmental visual disorder, amblyopia, especially monocular form-deprivation amblyopia, can lead to severe visual developmental impairments.
- Trial name
- NCT06760910
- Testing
- tDCS Stimulation, Anodal tDCS
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Visual Suppression, Amblyopia
Autostereoscopic Dynamic Near Vision Testing
This is an analysis of tests of near vision. Visual perception testing using a novel program on an interactive three dimensional electronic device: Autostereoscopic dynamic near games for monocular visual acuity, stereopsis and…
- Conditions
- Visual Suppression, Amblyopia, Color Vision Defects
- Trial name
- PDICheck (NCT04606355)
- Testing
- Visual Acuity, stereopsis, Color vision
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Alaska Blind Child Discovery
Amblyopia, Anisometropic, Pediatric
Multimodal Therapy in Anisometropic Amblyopia
This study aims to evaluate whether a six-month app-based visual therapy program, called AmblyoPlay, can improve visual acuity, oculomotor skills, and balance in children with anisometropic amblyopia (a type of "lazy eye" caused…
- Conditions
- Amblyopia, Anisometropic, Pediatric, Postural Balance, Vision Therapy
- Trial name
- MUTA (NCT07093840)
- Testing
- AmblyoPlay Digital Visual Therapy, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yusa Basoglu
2WIN-S Portable Refractor
Comparing Preschool-Aged Refractive Measurements and Amblyopia Risks Using the 2WIN-S Portable Refractor with Vision Screening by Cycloplegic Refraction in Bangkok
The goal of this diagnostic test is to compare the results of refraction and amblyopia risks between using 2WIN-S portable refractor and cycloplegic refraction in pre-school age.
- Trial name
- NCT06148519
- Testing
- 2WIN-S portable refractor
- Where
- Thailand
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Amblyopia
5 Years of Eye Screening for ARF in Children Aged <3 Years in Flanders
Researchers will investigate the distribution and evolution of amblyopia risk factors and other refractive errors in children younger than 3 years of age.
- Trial name
- NCT05612568
- Where
- Belgium
- Volunteers
- 250,000 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Amblyopia, Strabismus
Improving Quality Vision Outcomes in Managed Care Setting While Reducing Cost by Use of Accurate, Automated Screening
Amblyopia ("lazy eye") and strabismus (misaligned eyes) are medical eye conditions that combine as the leading causes of preventable vision loss in children.
- Trial name
- NCT02536963
- Testing
- Pediatric Vision Scanning device, Reference examination
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Hyperopia, Amblyopia
Effect of Peripheral Defocus on Axial Growth in Hyperopes
Hyperopia, also known as farsightedness, is a common type of refractive error where distant objects may be seen more clearly than objects that are near.
- Conditions
- Hyperopia, Amblyopia, Anisohyperopia
- Trial name
- NCT02686879
- Testing
- Multifocal contact lenses, Single vision contact lenses
- Where
- 2 sites in United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Aston University
Amblyopia, Strabismus
Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner
The purpose of this project is to compare the performance of the Pediatric Vision Scanner (PVS) with the Gold Standard Examination to determine the effectiveness of the PVS at detecting amblyopia and strabismus.
- Trial name
- NCT01726842
- Testing
- Pediatric Vision Scanner
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Amblyopia
Disinvestment Study of Population-Based Vision Screening in Children
The purpose of this study is to determine the optimal screening intervals and cost-effectiveness of population-based vision screening in preverbal children in the Netherlands.
- Trial name
- NCT01675193
- Testing
- Disinvestment protocol
- Where
- 2 sites in Netherlands
- Volunteers
- 10,803 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Amblyopia, Strabismus
Attention-based Binocular Training for Impaired Stereopsis (BRAVE)
This study evaluates a novel attention-based binocular visual search training paradigm designed to improve stereopsis (stereo vision) in individuals with impaired binocular vision.
- Conditions
- Amblyopia, Strabismus, Anisometropia, Binocular Vision Abnormalities
- Trial name
- BRAVE (NCT07803458)
- Testing
- Attention-Guided Dichoptic Visual Search Training, Zero-Disparity Dichoptic Visual Search Task
- Where
- 2 sites in Hong Kong
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Centre for Eye and Vision Research
Amblyopia
Docosahexaenoic Acid (DHA) Supplementation in Amblyopia
This study evaluates the addition of docosahexaenoic acid (DHA) to eye patching in the treatment of residual amblyopia in children ages 3 to 18 years old.
- Trial name
- NCT03402789
- Testing
- Docosahexaenoic Acid
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Visual Impairment, Amblyopia
Developing Better Computerised Vision Tests (CVTV)
Clinical vision measurements usually involve printed charts with an eye care professional interpreting patient responses to generate a score. Those scores determine the need for or outcome of treatment.
- Conditions
- Visual Impairment, Amblyopia, Macular Degeneration, Ophthalmic Disease
- Trial name
- CVTV (NCT06224751)
- Testing
- Near logMAR letter acuity, Near LogMAR word acuity, Red Green Stereoacuity
- Where
- United Kingdom
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Amblyopia
Light-deprivation Utilized to Mitigate Amblyopia
Amblyopia is an impairment in spatial vision caused by asymmetry in the quality of visual input across the two eyes during childhood.
- Trial name
- LUMA (NCT02685423)
- Testing
- Binocular deprivation 10 days, Vision training
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Amblyopia
Treatment of Residual Amblyopia With Donepezil
Amblyopia is the leading cause of monocular visual impairment in children and adults. Despite conventional treatment with patching or eye drops, many older children and adults do not achieve normal vision in the amblyopic eye.
- Trial name
- NCT01584076
- Testing
- Donepezil, Patching
- Where
- 3 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Amblyopia, Strabismus
Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner
The purpose of this project is to compare the performance of the Pediatric Vision Scanner (PVS) with the Gold Standard Examination to determine the effectiveness of the PVS at detecting amblyopia and strabismus.
- Trial name
- NCT01706991
- Testing
- Pediatric Vision Scanner eye scan
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Anisometropic Amblypia
Anisometropia Amblyopia Improved by Perceptual Learning and Patching
To compare the effects of perceptual learning with patching on improving visual acuity and contrast sensitivity in payient with anisometropic amblyopia.
- Trial name
- NCT00498641
- Testing
- computer program and patching
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)