Clinical trials: Ambulation Disorder, Neurologic
Spinal Cord Injuries, Neuropathic Pain
Brain Activity Patterns in Persons With Spinal Cord Injury and Neuropathic Pain After a Virtual Walking Training Program
The aim of this pilot study is to explore the association of changes in pain perception with changes in brain activity (functional Magnetic Resonance Imaging (fMRI)) and metabolic (Magnetic Resonance Spectroscopy (MRS)) patterns…
- Trial name
- VRandMRI (NCT05098587)
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Spinal Cord Injury
Validation of a Novel Robot-aided Assessment of Gait Ability
The aim of this study is the validation of a novel gait assessment method implemented in the Lokomat gait trainer with respect to established clinical gait assessment methods.
- Trial name
- NCT02425332
- Testing
- Lokomat gait trainer
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Cerebral Palsy (CP), Typically Developing Children
The Effect of Perturbation Training on Reactive Balance in Children With Cerebral Palsy
The aim of this project was to evaluate whether perturbation training influences reflex modulation in children with spastic CP and whether changed reflex modulation leads to improved reactive balance and walking.
- Trial name
- NCT07818928
- Testing
- Balance training on a moving platform
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cerebral Palsy, Family Characteristics
Functionality and Family Characteristics in Children With Cerebral Palsy
The aim of this study was to investigate the effect of family characteristics on functional level in children with Spastic Type Cerebral Palsy who are able to walk.
- Trial name
- NCT06439446
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Stroke, Hemiparesis
Stimulation Combined With Powered Motorized Orthoses for Walking After Stroke
Objective: The goal of this study is to implement and test a neuro-mechanical gait assist (NMGA) device to correct walking characterized by muscle weakness, incoordination or excessive tone in Veterans with hemiparesis after…
- Trial name
- NCT04116671
- Testing
- Neuromechanical Gait Assist
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injury (TBI) Patients
Home-Based Walking for Thinking Skills in Persons With TBI
The purpose of this research study is to investigate the effects of a home-based 3-month long walking exercise program on cognitive (thinking) performance in persons with TBI.
- Trial name
- SWEAT-TBI (NCT07733284)
- Testing
- Walking
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Kessler Foundation
Cerebral Palsy, Balance
The Relationship of Forward and Backward Walking with SMC, Trunk Control and Balance in Children with Cerebral Palsy
Children aged between 6-18 years old, diagnosed with cerebral palsy and meeting the inclusion criteria, will be included in this study.
- Conditions
- Cerebral Palsy, Balance, Gait Disorders in Children
- Trial name
- NCT05962749
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Alanya Alaaddin Keykubat University
Stroke, Viscoelastic Property
The Effect of Percussion Massage Therapy in Stroke Patients
Stroke is an acute neurological condition resulting from cerebral ischemia or hemorrhage, frequently leading to impaired motor function, increased muscle tone, and deficits in balance and gait.
- Conditions
- Stroke, Viscoelastic Property, Rehabilitation
- Trial name
- NCT07454655
- Testing
- exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Sanko University
Cerebral Palsy
The Effect of Treadmill Back Walking Training on Balance and Function in Cerebral Palsy
The aim of this study was to investigate the effect of treadmill back walking training on balance and function in cerebral palsy.
- Trial name
- CP (NCT04136678)
- Testing
- walking training
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul Medipol University Hospital
Osteoarthritis, Knee
Effect of Knee Pain on Walking Biomechanics
The goal of this study is to determine if pain in one knee influences loading of the other knee during different types of walking.
- Trial name
- NCT05670236
- Testing
- Lidocaine Hydrochloride
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Cardiac Failure, Heart Failure
Insomnia Self-Management in Heart Failure
Chronic insomnia may contribute to the development and exacerbation of heart failure (HF), incident mortality and contributes to common and disabling symptoms (fatigue, dyspnea, anxiety, depression, excessive daytime sleepiness…
- Conditions
- Cardiac Failure, Heart Failure, Congestive Heart Failure, Heart Failure, Congestive
- Trial name
- HSS (NCT02660385)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Self-Management Education for Heart Failure
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Yale University
Spinal Cord Injury
Orthostatic Tolerance During FES (Functional Electrical Stimulation)-Walking in Paraplegia
Objective: The objective of this research is to undertake a safety and viability study of FES-evoked stepping in individuals with paraplegia.
- Trial name
- NCT00108043
- Testing
- FES-evoked functional upright gait
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- University of Sydney
Charcot Marie Tooth Disease (CMT), Pes Cavovarus
Walking Function Outcomes Following Surgical Correction With Rehabilitation Versus Physical Therapy Alone in Charcot-Marie-Tooth Disease: A Bidirectional Cohort Study
The goal of this study is to compare changes in walking ability in people with Charcot-Marie-Tooth disease (CMT) who receive two different treatment approaches for foot deformities that affect walking.
- Conditions
- Charcot Marie Tooth Disease (CMT), Pes Cavovarus, Surgery, Exercise Training
- Trial name
- CMT-WALK (NCT07432035)
- Testing
- Functional Surgery plus Rehabilitation, Physical Exercise
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Stroke, Depression - Major Depressive Disorder
Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking
Investigators primary aim is to carry out a two-site, randomized, double-blind, sham-controlled, phase II trial to systematically examine the potential for aerobic exercise (AEx) to enhance the anti-depressant benefits of rTMS in…
- Conditions
- Stroke, Depression - Major Depressive Disorder, Walking Impairment
- Trial name
- RESTORATION (NCT07050355)
- Testing
- rTMS, AEx
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- Medical University of South Carolina
Sarcopenia, Diagnostic
Sarcopenia Cut-points and Functionality in Older Adults
This is a cross-sectional study conducted in older adults living in Valencia Province in order to establish the cut-off points of the multicriteria diagnostic of sarcopenia through functionality and frailty variables.
- Trial name
- SARCOFUNC (NCT03832608)
- Testing
- No intervention
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- University of Valencia
Cerebral Palsy, Mobility Limitation
Robotic Walking for Children Who Cannot Walk
A common problem among children with nervous system disorders is difficulty walking on their own. This has impacts beyond mobility including short and long-term health conditions associated with physical inactivity and different…
- Conditions
- Cerebral Palsy, Mobility Limitation, Brain Injuries, Spinal Cord Injuries
- Trial name
- RoWaCaWa (NCT05473676)
- Testing
- Robotic Training Period
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- University of Calgary
Stroke
Reliability of Community Ambulation Ability, Fall Risk, and Dynamic Visual Acuity Assessments in Stroke
Nearly half of individuals with stroke experience limitations in community ambulation, and 35.7% of community-dwelling stroke survivors experienced falls while walking, indicating that falls are common during routine daily…
- Trial name
- NCT07494487
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Yang Ming Chiao Tung University
Stroke, Hemiparesis
Effects of Different Types of Augmented Feedback on Intrinsic Motivation and Spatiotemporal Gait Performance After Stroke
Investigate development of an Innovative Instrument on Robot-Aided and Virtual Reality Rehabilitation for Intelligent Physical Training (i.e. gait and stepping) of Individuals post-stroke.
- Conditions
- Stroke, Hemiparesis, Walking, Difficulty
- Trial name
- NCT04740060
- Testing
- Augmented Feedback without Virtual Reality(VR, Augmented Feedback with Non-Game based VR, Augmented Feedback with Game based VR
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- University of Alabama at Birmingham
Abdominal Obesity
Effects of Weight Reduction on Sleep and Alertness in Long-distance Truck and Bus Drivers
The study is a year-long health-behaviour intervention in obese, male truck-drivers to lose weight moderately by 10%, using monthly individual counseling.
- Trial name
- SF-Truck (NCT00893646)
- Testing
- weight loss counseling
- Where
- 3 sites in Finland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Stroke
Walking Study for Stroke Rehabilitation
The primary purpose of this study is to determine the effects of reinforcement of walking speed on recovery of walking speed over the course of inpatient rehabilitation for people after stroke.
- Trial name
- SIRROWS (NCT00428480)
- Testing
- Daily reinforcement of walking speed (DRS), No reinforcement of walking speed (NRS)
- Where
- 24 sites in United States, Austria and 8 more
- Volunteers
- 216 people
- Sponsor
- University of California, Los Angeles
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