Clinical trials: Ambulation Disorder, Neurologic
Cirrhoses, Liver
The Application of Lifestyle Enhancing Validated Integrative Therapies for Everyday Pain in Cirrhosis
The goal of this clinical trial is to test a low-touch vs high-touch drug-free pain self-management program that may help lower pain and improve quality of life for adults with cirrhosis and pain.
- Trial name
- ALLEVIATE-C (NCT07792850)
- Testing
- High-touch self-management program, Low-touch self-management program
- Where
- 8 sites in United States
- Volunteers
- 625 people
- Sponsor
- University of Pennsylvania
Pregnancy Related, Epidural; Anesthesia, Headache
Inertial Sensors for Obstetrical Walking Epidural Tracking
Freedom of movement and the ability to walk are crucial during the first stage of labor, potentially reducing labor duration, cesarean section risk, epidural analgesia use, and bladder catheterization.
- Conditions
- Pregnancy Related, Epidural; Anesthesia, Headache, Labor Complication
- Trial name
- MOTION-EASE (NCT06471790)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon
Stroke, Stroke, Ischemic
Ischemic Conditioning Improves Walking Function Post Stroke
This innovative study will address scientific and clinical areas relatively unexplored in chronic stroke that could lead to greater recovery of walking.
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Stroke, Cardiovascular
- Trial name
- NCT04038697
- Testing
- Ischemic Conditioning, Treadmill Training
- Where
- 2 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Stroke
Comparative Effects of Dual Task Training and Repetitive Task Training in Chronic Stroke
Chronic stroke survivors those who have had a stroke for more than six months frequently experience long-lasting, incapacitating deficits, particularly when it comes to motor task impairment.
- Trial name
- NCT07726017
- Testing
- Dual task training, Repetitive task training
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Riphah International University
Healthy Older Adults, Parkinson Disease
Brain Activity, Cognitive Function, and Walking Ability in Parkinson's Disease
The dual-task automated walking performance in people with Parkinson\'s disease (PD) is affected by their gait disturbances and impaired executive functions.
- Trial name
- NCT06588920
- Testing
- Cognitive function, gait, and electroencephalogram
- Where
- 2 sites in Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Spinal Cord Injuries or Similar Neurological Weakness
EKSO Trial: Powered Exoskeleton for Ambulation in Subjects With Spinal Cord Injury (SCI)
This study seeks to test the safety and efficacy of the Esko device in SCI population and in populations with similar neurological weakness to the SCI population.
- Trial name
- EKSO (NCT01701388)
- Testing
- Ekso exoskeleton
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Shirley Ryan AbilityLab
Cerebral Palsy Spastic Diplegia
Cerebral Palsy: Short-burst Interval Training
This study examines the effect of short burst interval treadmill training in ambulatory children with cerebral palsy. Half the sample will receive 20 sessions of training over 4 weeks, while half will receive the training over 10…
- Trial name
- NCT03373890
- Testing
- Short Burst Interval Locomotor Treadmill Training (SBLTT)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Seattle Children's Hospital
Stroke
Cortical Priming to Optimize Gait Rehabilitation Post Stroke
Over four million stroke survivors currently living in the United States are unable to walk independently in the community. To increase the effectiveness of gait rehabilitation, it is critical to develop therapies that are based…
- Trial name
- NCT03492229
- Testing
- tDCS, AMT, Treadmill training
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- University of Illinois Chicago
Fatigue, Cardiopulmonary Arrest
Post-Coronavirus Disease of 2019 (COVID-19) Rehabilitation Clinics in Saudi Arabia
This intervention study aims to evaluate the before and after changes in physical fitness, cardiorespiratory status, exercise capacity, fatigue, anxiety, dyspnea, psychoemotional conditions, and quality of life through 3 sessions…
- Conditions
- Fatigue, Cardiopulmonary Arrest, Physical Inactivity, Muscle Weakness
- Trial name
- NCT05799534
- Testing
- Physical Therapy Rehabilitation
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Majmaah University
Stroke, Neurological Diseases or Conditions
Development and Efficacy of a Novel, Cost-Effective Gait Training Device Utilized at Home for Stroke Survivors
This pilot, parallel-group randomized controlled trial will evaluate the feasibility, safety, usability, and preliminary efficacy of the Rise\&Walk InHome (RWH), a novel robotic gait training device designed for home use after…
- Conditions
- Stroke, Neurological Diseases or Conditions, Hemiparesis;Poststroke/CVA, Gait Disorders, Neurologic
- Trial name
- NCT07250425
- Testing
- Rise&Walk InHome by Healing Innovations
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Healing Innovations
Stroke, Hemiplegia
Implant for Walking After Stroke
This is a device study that will evaluate the effect of an implanted stimulator on improving walking in stroke survivors. There are two phases in the study: 1) Screening - this phase determines if the individual is a good…
- Conditions
- Stroke, Hemiplegia, Gait, Hemiplegic
- Trial name
- NCT05740540
- Testing
- IRS-8, IST 12 & IST 16
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- MetroHealth Medical Center
Stroke, Acute, Walking, Difficulty
Cortical Processes During Walking Post-stroke
The study aims to use novel mobile imaging techniques with high-density electroencephalography (EEG) to quantify cortical processes synchronized to the biomechanics of walking.
- Trial name
- NCT05710029
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida
Multiple Sclerosis
Study of Oral Fampridine-SR in Multiple Sclerosis
To assess the safety and efficacy of 10 milligram (mg) twice a day (b.i.d.) Fampridine-SR in patients diagnosed with multiple sclerosis (MS), in a double-blind, placebo-controlled, parallel group study.
- Trial name
- NCT00127530
- Testing
- Fampridine-SR
- Where
- 34 sites in United States, Canada
- Volunteers
- 300 people
- Sponsor
- Acorda Therapeutics
Stroke
Multi-task Gait Training Mode to Enhance Walking Function in Patients With Chronic Stroke
The objective of this study is to investigate psychometric properties of dual-task walking assessments and compare effects of multi-task walking interventions on walking for patients with chronic stroke.
- Trial name
- NCT04328779
- Testing
- The multi-task overground walking training, The multi-task treadmill walking training, Traditional rehabilitation
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- Chang Gung University
Multiple Sclerosis
Improving Gait in Multiple Sclerosis (MS) - Strength Training or Treadmill Walking?
The objective of this study is to evaluate the effect of strength training for the lower extremities and treadmill training on walking ability in persons with Multiple Sclerosis.
- Trial name
- NCT01074827
- Testing
- Strength training and treadmill training
- Where
- Norway
- Volunteers
- 28 people
- Sponsor
- St. Olavs Hospital
Duchenne Dystrophy Muscular
Biomechanical and Morphological Changes in Dystrophic Muscle
The loss of ability to walk in many children with DMD (Duchenne muscular Dystrophy) is a pejorative event. Biomechanical and morphological unknowledge about the loss of the walk ability in children with DMD is an obstacle in…
- Trial name
- MARCHE-DMD (NCT02472990)
- Where
- 10 sites in France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Parkinson, Parkinson Disease
Cerebellar rTMS Theta Burst for Dual-task Walking in Parkinson's Disease
Objective of the study: To test the efficacy of theta burst cerebellar stimulation on dual task walking in Parkinson's disease using a cross-over design and wearing sensors technology Design: Twenty Parkinson's disease patients…
- Conditions
- Parkinson, Parkinson Disease, Gait Disorders, Neurologic, Parkinsonism
- Trial name
- NCT04238000
- Testing
- repetitive transcranial magnetic stimulation
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Europea di Ricerca Biomedica Ferb Onlus
Chronic Obstructive Pulmonary Disease (COPD)
Effects of Walking and Home-Based Pulmonary Rehabilitation on Anxiety and Sleep Quality
Although pulmonary rehabilitation plays an important role in increasing exercise tolerance and reducing hospitalizations in patients with chronic obstructive pulmonary disease (COPD), adherence to treatment is often low.
- Trial name
- NCT06862713
- Testing
- pulmonary rehabilitation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Spinal Cord Injury
Comparison of Post-pinal Cord Injury (SCI) Locomotor Training Techniques
Background: Body weight supported (BWS) locomotor training improves overground walking ability in individuals with motor-incomplete spinal cord injury (SCI).
- Trial name
- NCT01095380
- Testing
- Locomotor training
- Volunteers
- 74 people
- Sponsor
- University of Miami
Primary Insomnia
Brisk Walking Training Compared with Cognitive Behavioral Therapy for the Treatment of Chronic Primary Insomnia in People Aged 60 Years or Above: a Randomized, Partially Blinded, Non-inferiority Trial
This study is a single-blinded (outcome assessor) and parallel-group non-inferiority RCT. Chinese older adults aged ≥60 years with chronic primary insomnia will be randomized evenly (1:1) to either the brisk walking training…
- Trial name
- NCT06850272
- Testing
- Brisk walking, Cognitive-behavioral therapy for insomnia
- Where
- Hong Kong
- Volunteers
- 92 people
- Sponsor
- Chinese University of Hong Kong
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