Clinical trials: Ambulatory Blood Pressure
Hypertension
PROBE Investigation of the Safety & Efficacy of Telmisartan (Micardis®) vs Ramipril (Altace®) Using ABPM in HTN
Demonstrate that telmisartan 80mg was at least as effective and possibly superior to ramipril 5mg \& 10mg in lowering mean ambulatory DBP and SBP during the last 6 hrs of the 24-hr dosing interval in mild-to-moderate…
- Trial name
- NCT00274599
- Testing
- Telmisartan, Ramipril
- Where
- 74 sites in United States, Canada
- Volunteers
- 812 people
- Sponsor
- Boehringer Ingelheim
Essential Hypertension
Efficacy and Safety of Aliskiren 300mg Compared to Irbesartan 300mg and Ramipril 10 mg in the Setting of a Missed Dose for Patients With Essential Hypertension.
The purpose of this study is to investigate the efficacy (blood pressure lowering effect) and safety of aliskiren given to hypertensive patients after a missed dose.
- Trial name
- NCT00343551
- Testing
- Aliskiren
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 654 people
- Sponsor
- Novartis
Hypertension
Efficacy and Safety Comparison of Azilsartan Medoxomil to Valsartan in Participants With Essential Hypertension
The purpose of this study is to compare the efficacy and safety of TAK-491 (azilsartan medoxomil), once daily (QD), to valsartan in participants with essential hypertension.
- Trial name
- NCT00591578
- Testing
- Azilsartan Medoxomil, Valsartan
- Where
- 88 sites in United States, Chile and 2 more
- Volunteers
- 984 people
- Sponsor
- Takeda
Osteoarthritis, Hypertension
A Study to Assess the Effects of Naproxcinod and Naproxen on Blood Pressure Measurements in Osteoarthritis Patients With Controlled High Blood Pressure
To assess the effect of naproxcinod vs. naproxen on arterial blood pressure patients with osteoarthritis and controlled essential hypertension
- Trial name
- HCT3012-X-111 (NCT00662610)
- Testing
- naproxcinod 375 mg -750 mg -1125 mg bid, naproxen 250 mg - 500mg -750 mg bid
- Where
- 29 sites in United States
- Volunteers
- 120 people
- Sponsor
- NicOx
Hypertension
Telmisartan Versus Amlodipine in Patients With Mild-to-Moderate Hypertension
The primary aim of the trial is the effect of telmisartan versus amlodipine in lowering ambulatory diastolic and/or systolic blood pressures in the last six hours of the dosing interval in patients with mild-to-moderate…
- Trial name
- NCT02177409
- Testing
- Telmisartan, Amlodipine
- Volunteers
- 431 people
- Sponsor
- Boehringer Ingelheim
Hypertension
MICARDIS® and Valsartan in Patients With Mild-to-Moderate Hypertension Using Ambulatory Blood Pressure Monitoring
The primary aim of the trial was to compare the effect of telmisartan and valsartan in lowering ambulatory diastolic and/or systolic blood pressure in the last six hours of the dosing interval.
- Trial name
- NCT02177396
- Testing
- Telmisartan, Valsartan
- Volunteers
- 426 people
- Sponsor
- Boehringer Ingelheim
Hypertension
Efficacy and Safety of Azilsartan Medoxomil, Once Daily (QD), Co-Administered With Amlodipine in Participants With Essential Hypertension
The purpose of this study is to evaluate the efficacy and safety of azilsartan medoxomil, once daily (QD), co-administered with amlodipine in treating individuals with essential hypertension, compared to treatment with amlodipine…
- Trial name
- NCT00591266
- Testing
- Azilsartan Medoxomil and amlodipine, Amlodipine
- Where
- 50 sites in United States
- Volunteers
- 566 people
- Sponsor
- Takeda
Hypertension
Prospective Randomised Investigation of the Safety and Efficacy of Micardis® vs Ramipril Using ABPM
The primary objective of this study is to demonstrate that telmisartan 80 mg (MICARDIS®) is at least as effective and possibly superior to ramipril 5mg and 10mg in lowering mean ambulatory diastolic blood pressure (DBP) and…
- Trial name
- PRISMA (NCT00274612)
- Testing
- Telmisartan, Ramipril
- Where
- 62 sites in Austria, France and 6 more
- Volunteers
- 801 people
- Sponsor
- Boehringer Ingelheim
Osteoarthritis, Hypertension
To Assess the Effect of Naproxcinod Versus Naproxen and Ibuprofen on Arterial Blood Pressure in Osteoarthritis Patients With Controlled Essential Hypertension
To assess the effect of naproxcinod vs. naproxen and ibuprofen on arterial blood pressure in patients with osteoarthritis and controlled essential hypertension
- Trial name
- HCT3012-X-112 (NCT00662896)
- Testing
- naproxcinod 375 mg bid, naproxcinod 750 mg bid, naproxen 250 mg bid
- Where
- 57 sites in United States
- Volunteers
- 300 people
- Sponsor
- NicOx
Hypertension, Hypercholesterolemia
Efficacy and Safety of Valsartan and the Combination of Valsartan and Simvastatin
This study will assess and compare the efficacy and safety of valsartan and the combination of valsartan and simvastatin in patients with high blood pressure and high cholesterol.
- Conditions
- Hypertension, Hypercholesterolemia, Dyslipidemia
- Trial name
- NCT00385931
- Testing
- Valsartan and simvastatin
- Where
- United States
- Volunteers
- 412 people
- Sponsor
- Novartis
Osteoarthritis, Controlled Hypertension
Safety and Efficacy of Lumiracoxib in Patients With Osteoarthritis and With Controlled Hypertension
This study will investigate the effect on ambulatory blood pressure of lumiracoxib 100 mg once daily versus ibuprofen 600 mg three times a day in osteoarthritis patients with controlled hypertension.
- Trial name
- NCT00267176
- Testing
- lumiracoxib
- Where
- 2 sites in United States, Germany
- Volunteers
- 1,020 people
- Sponsor
- Novartis Pharmaceuticals
Blood Pressure
Clinical Trial of Wrist Ambulatory Blood Pressure Monitor in Conformance With the ISO 81060-2:2018+AMD1:2020+AMD2:2024.
The accuracy and safety of the Wrist Ambulatory Blood Pressure Monitor (Model: RIV-B10) were assessed according to the requirements of ISO 81060-2:2018+AMD1:2020+AMD2:2024.
- Trial name
- NCT07713576
- Testing
- Wrist Ambulatory Blood Pressure Monitor/mercury sphygmomanometer
- Where
- China
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Huawei Device Co., Ltd
Healthy Volunteer
Study to Investigate the Effect of GSK1014802 on Ambulatory Blood Pressure
In this study the investigators will determine whether there is any effect of GSK1014802 on ambulatory blood pressure. This will be a randomized, double-blind, placebo-controlled, repeat dose, 2 period cross-over study conducted…
- Trial name
- NCT00955396
- Testing
- GSK1014802
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Biogen
Hypertension
A Study of the Effect of MK-8457 on Blood Pressure in Hypertensive Participants (MK-8457-004-AM1)
This study will evaluate the effect of treatment with multiple doses of MK-8457 on systolic blood pressure in participants with mild to moderate hypertension in addition to safety and tolerability.
- Trial name
- NCT01446003
- Testing
- MK-8457
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Merck Sharp & Dohme LLC
Hypertension
Antihypertensive Effect of Different Doses of Rostafuroxin in Comparison With Losartan
The principal aim of the study is to demonstrate that Rostafuroxin is able to induce a more pronounced reduction of arterial blood pressure respect to Losartan, in hypertensive patients carrying at least one of the pre-specified…
- Trial name
- NCT03217825
- Testing
- Rostafuroxin, Losartan
- Where
- Taiwan
- Volunteers
- 240 people
- Sponsor
- Windtree Therapeutics
Hypertension
Study to Evaluate Efficacy of Micardis® (Telmisartan) and Valsartan in Patients With Mild-to-moderate Hypertension After Missing One Dose Using Ambulatory Blood Pressure Monitoring
The primary aim of the trial is to compare telmisartan 80 mg to valsartan 160 mg in lowering diastolic blood pressure in patients who missed a dose of their medication, as measured by ABPM (change from baseline in mean DBP over…
- Trial name
- NCT02242318
- Testing
- Telmisartan, Valsartan
- Volunteers
- 440 people
- Sponsor
- Boehringer Ingelheim
Hypertension, Blood Pressure, High
Ramipril and Hydrochlorothiazide Alone and in Combination for the Treatment of Essential Hypertension
The purpose of this study is to determine if there is greater blood pressure reduction using ramipril or hydrochlorothiazide alone or ramipril and hydrochlorothiazide together.
- Trial name
- NCT00355589
- Testing
- Ramipril and hydrochlorothiazide
- Where
- 60 sites in United States
- Sponsor
- Pfizer
Hypertension
OBPM_HARMONY: Physiological Data Recording Over 24 Hours Using the Continual Optical Hilo Blood Pressure Monitor and an Ambulatory Blood Pressure Monitor
The OBPM_HARMONY study will enroll a minimum of 300 participants at the CHUV site in Lausanne, Switzerland. Each participant will complete two study visits at CHUV, scheduled at least 24.5 hours apart.
- Trial name
- OBPM_HARMONY (NCT07099716)
- Testing
- Wearing Hilo band, Ambulatory Blood Pressure Monitor, and Hydrostatic Pressure monitor
- Volunteers
- 330 people
- Sponsor
- Aktiia SA
Hypertension
Effects of Doxazosin Gastrointestinal Therapeutic System on Ambulatory Blood Pressure and Cardiovascular Risk Factors in Uncontrolled Hypertensive Patients
The primary objective was to determine the effects of the Gastrointestinal Therapeutic System (GITS) formulation of Doxazosin when used in combination therapy with the 5 major classes of antihypertensive agents as measure by…
- Trial name
- NCT00646841
- Testing
- Doxazosin gastrointestinal therapeutic system (GITS)
- Where
- 7 sites in Italy, Spain and 1 more
- Volunteers
- 89 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Prehypertension
Effect and Safety of Marealis RPC (Refined Peptide Concentrate) in Mild or Moderate Hypertensive Subjects
Hypertension is an important risk factor of cardiovascular (CVD) and renal diseases. Epidemiological studies show that there is a direct relationship between blood pressure and CVD, and cardiovascular mortality increases…
- Trial name
- NCT01974570
- Testing
- Marealis refined peptide concentrate
- Where
- 13 sites in United States, Canada and 2 more
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.