Clinical trials: Ambulatory Blood Pressure
Hypertension, Resistant to Conventional Therapy
Addition of Homeopathy in Patients With Resistant Arterial Hypertension
Resistant hypertension (RHTN) is a common clinical problem faced by both primary care clinicians and specialists worldwide. Patients with RHTN have higher rates of cardiovascular events and mortality compared with patients with…
- Trial name
- NCT02124473
- Testing
- Homeopathy
- Where
- 2 sites in India
- Volunteers
- 79 people
- Sponsor
- Macmillan Research Group UK
Blood Pressure, Human Experimentation
Safety Study Comparing Phenylephrine HCL Extended Release Tablets 30 mg and Placebo (Study CL2007-07)(P07529)(COMPLETED)
Randomized, placebo-controlled double-blind, crossover design study; 116 subjects randomized on Day 1 to obtain 98 completed subjects.
- Trial name
- NCT00874120
- Testing
- Phenylephrine Hydrochloride (HCl) Extended-Release tablets 30 mg
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Bayer
Rheumatoid Arthritis
Study of the Effect of Fostamatinib Twice Daily on Blood Pressure in Patients With Rheumatoid Arthritis
The purpose of this study is to evaluate the effect of fostamatinib compared to placebo on ambulatory blood pressure in patients with active rheumatoid arthritis who are taking a disease-modifying anti-rheumatic drug (DMARD).
- Trial name
- Oskira ABPM (NCT01563978)
- Testing
- fostamatinib
- Where
- 56 sites in United States, Bulgaria and 5 more
- Volunteers
- 266 people
- Sponsor
- AstraZeneca
Blood Pressure
Clinical Trial of Wrist Ambulatory Blood Pressure Monitor in Conformance With the ISO 81060-2:2018+AMD1:2020+AMD2:2024.
The accuracy and safety of the Wrist Ambulatory Blood Pressure Monitor (Model: RIV-B10) were assessed according to the requirements of ISO 81060-2:2018+AMD1:2020+AMD2:2024.
- Trial name
- NCT07713576
- Testing
- Wrist Ambulatory Blood Pressure Monitor/mercury sphygmomanometer
- Where
- China
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Huawei Device Co., Ltd
Hypertension
Effect of PRM-125 on Ambulatory Blood Pressure
Evaluation of Once-Daily PRM125 On Ambulatory Blood Pressure in Adults with Hypertension
- Trial name
- NCT05195827
- Testing
- PRM-125
- Where
- United States
- Sponsor
- PRM Pharma, LLC
Major Depressive Disorder
A Study of LY2216684 in Major Depressive Disorder in Patients Taking Selective Serotonin Reuptake Inhibitors
The purpose of this study is to determine the effect of LY2216684 on heart rate and blood pressure in research participants with MDD who are being treated with an SSRI (selective serotonin reuptake inhibitors).
- Trial name
- NCT01263223
- Testing
- LY2216684
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Eli Lilly and Company
Blood Pressure, Schizophrenia
Trial to Study the Effect of CVL-231 on 24-Hour Ambulatory Blood Pressure in Participants With Schizophrenia
The purpose of this trial is to characterize the effects of 2 oral doses (over 8 weeks total) of CVL-231 on ambulatory blood pressure and heart rate in patients with stable schizophrenia.
- Trial name
- NCT05245539
- Testing
- CVL-231
- Where
- 10 sites in United States
- Volunteers
- 151 people
- Sponsor
- Cerevel Therapeutics, LLC
Atherosclerotic Cardiovascular Disease
A Study to Assess the Effect of AZD0780 on Ambulatory Blood Pressure
This is a Phase II, multi-centre, randomized, double-blind, placebo-controlled, crossover study to evaluate the effect of AZD0780 Dose 1 versus placebo on systolic blood pressure (SBP) at Week 4, as measured by 24-hour ambulatory…
- Trial name
- AZD0780-ABPM (NCT06692764)
- Testing
- AZD0780
- Where
- 26 sites in United States
- Volunteers
- 202 people
- Sponsor
- AstraZeneca
Hypertension
A Study of the Effect of MK-8457 on Blood Pressure in Hypertensive Participants (MK-8457-004-AM1)
This study will evaluate the effect of treatment with multiple doses of MK-8457 on systolic blood pressure in participants with mild to moderate hypertension in addition to safety and tolerability.
- Trial name
- NCT01446003
- Testing
- MK-8457
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Merck Sharp & Dohme LLC
Cardiovascular Diseases
Evaluating the Effectiveness of a Computerized Medication Adherence System at Reducing Cardiovascular Disease Risk Factors
High blood pressure and high cholesterol are both causes of cardiovascular disease (CVD), and it is important for people with these conditions to adhere to their medication regimens.
- Trial name
- NCT00796172
- Testing
- Medication Adherence System (MAS), Usual Care
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- PHCC LP
Essential Hypertension
Efficacy and Safety of Aliskiren 300mg Compared to Irbesartan 300mg and Ramipril 10 mg in the Setting of a Missed Dose for Patients With Essential Hypertension.
The purpose of this study is to investigate the efficacy (blood pressure lowering effect) and safety of aliskiren given to hypertensive patients after a missed dose.
- Trial name
- NCT00343551
- Testing
- Aliskiren
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 654 people
- Sponsor
- Novartis
Hypertension
PROBE Parallel 6-week Treatment Comparing Telmisartan/Hydrochlorothiazide (HCT) (40/12.5 or 80/12.5) With Losartan/HCT (50/12.5) Using Ambulatory Blood Pressure Monitoring (ABPM)
To demonstrate that Telmisartan combined with Hydrochlorothiazide (MICARDIS® HCT) is superior to Losartan with Hydrochlorothiazide (Hyzaar®) in lowering blood pressure in mild-moderate hypertensives.
- Trial name
- NCT00274638
- Testing
- Telmisartan & Hydrochlorothiazide, Losartan & Hydrochlorothiazide, ABPM
- Where
- 69 sites in United States
- Volunteers
- 805 people
- Sponsor
- Boehringer Ingelheim
Chronic Spontaneous Urticaria
A Multicenter, Open-label Phase 3 Study: Ambulatory Blood Pressure Monitoring in Adult Patients With Chronic Spontaneous Urticaria Inadequately Controlled by H1-antihistamines Treated With Remibrutinib up to 12 Weeks.
The purpose of this study was to assess the effect of remibrutinib 25 mg twice a day (b.i.d.) open-label on Systolic Blood Pressure (SBP) measured as a change in 24-hour weighted average SBP from baseline to Week 4 assessed by…
- Trial name
- NCT05795153
- Testing
- LOU064
- Where
- 44 sites in United States, Argentina and 8 more
- Volunteers
- 144 people
- Sponsor
- Novartis Pharmaceuticals
Diabetes Mellitus Type 2, Hypertension
MATCHED (MC-1 and ACE Therapeutic Combination for Hypertensive Diabetics)
The purpose of this study is to determine whether MC-1 alone and in combination with an ACE inhibitor is effective in reducing blood pressure and metabolic dysfunctions associated with diabetes
- Conditions
- Diabetes Mellitus Type 2, Hypertension, Metabolic Syndrome
- Trial name
- NCT00157729
- Testing
- pyridoxal-5'-phosphate with and without ACE inhibitor
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Medicure
Hypertension
Telmisartan Compared to Losartan + Hydrochlorothiazide in Patients With Mild-to-moderate Essential Hypertension
The general aim and clinical objective of this trial is to determine the effect of telmisartan 80 mg compared to losartan 50 mg + HCTZ (Hydrochlorothiazide) 12.5 mg on reduction of blood pressure (BP) in patients with mild to…
- Trial name
- NCT02183701
- Testing
- Telmisartan, Losartan + Hydrochlorothiazide
- Volunteers
- 715 people
- Sponsor
- Boehringer Ingelheim
Hypertension
Prospective Randomised Investigation of the Safety and Efficacy of Micardis® vs Ramipril Using ABPM
The primary objective of this study is to demonstrate that telmisartan 80 mg (MICARDIS®) is at least as effective and possibly superior to ramipril 5mg and 10mg in lowering mean ambulatory diastolic blood pressure (DBP) and…
- Trial name
- PRISMA (NCT00274612)
- Testing
- Telmisartan, Ramipril
- Where
- 62 sites in Austria, France and 6 more
- Volunteers
- 801 people
- Sponsor
- Boehringer Ingelheim
Hypertension, Blood Pressure, High
Ramipril and Hydrochlorothiazide Alone and in Combination for the Treatment of Essential Hypertension
The purpose of this study is to determine if there is greater blood pressure reduction using ramipril or hydrochlorothiazide alone or ramipril and hydrochlorothiazide together.
- Trial name
- NCT00355589
- Testing
- Ramipril and hydrochlorothiazide
- Where
- 60 sites in United States
- Sponsor
- Pfizer
Hypertension
OBPM_HARMONY: Physiological Data Recording Over 24 Hours Using the Continual Optical Hilo Blood Pressure Monitor and an Ambulatory Blood Pressure Monitor
The OBPM_HARMONY study will enroll a minimum of 300 participants at the CHUV site in Lausanne, Switzerland. Each participant will complete two study visits at CHUV, scheduled at least 24.5 hours apart.
- Trial name
- OBPM_HARMONY (NCT07099716)
- Testing
- Wearing Hilo band, Ambulatory Blood Pressure Monitor, and Hydrostatic Pressure monitor
- Volunteers
- 330 people
- Sponsor
- Aktiia SA
Hypertension
Effects of Telmisartan by Ambulatory Blood Pressure Monitoring (ABPM) in Chinese Patients With Mild to Moderate Essential Hypertension
To assess the trough/peak ratio of 40 mg Telmisartan tablet by ambulatory blood pressure monitoring in Chinese patients with mild to moderate essential hypertension
- Trial name
- NCT02206659
- Testing
- Telmisartan
- Volunteers
- 20 people
- Sponsor
- Boehringer Ingelheim
Healthy Volunteer
Study to Investigate the Effect of GSK1014802 on Ambulatory Blood Pressure
In this study the investigators will determine whether there is any effect of GSK1014802 on ambulatory blood pressure. This will be a randomized, double-blind, placebo-controlled, repeat dose, 2 period cross-over study conducted…
- Trial name
- NCT00955396
- Testing
- GSK1014802
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Biogen