Clinical trials: Amelogenesis Imperfecta
Amelogenesis Imperfecta
Oral Health Related Quality of Life of Children With Amelogenesis Imperfecta
This project aims to evaluate the impact of anterior veneer treatment on oral health-related quality of life in children with amelogenesis imperfecta (AI).
- Trial name
- NCT07250906
- Testing
- Veneers
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Amelogenesis Imperfecta, Dental Caries
Clinical Performance of Composites in Patients With Amelogenesis Imperfecta
In AI patients, adhesion still remains the first option in order to achieve an early, minimally invasive intervention, and the altered enamel still represents an acceptable substrate for bonding in some AI variants.
- Conditions
- Amelogenesis Imperfecta, Dental Caries, Dental Composite
- Trial name
- NCT04897724
- Testing
- dental composite
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Neslihan Tekçe
Dentinogenesis Imperfecta, Amelogenesis Imperfecta
Psycho-social Impact of Amelogenesis and Dentinogenesis Imperfecta
The purpose of this research is to study the impact of dentinogenesis (DI) and amelogenesis (AI) imperfecta on oral quality of life, exposure to bullying and dental anxiety in a population of adolescents.
- Trial name
- AiDiBull (NCT04927962)
- Testing
- Questionnaires
- Where
- 7 sites in France
- Volunteers
- 87 people
- Sponsor
- University Hospital, Toulouse
Amelogenesis Imperfecta
E. Max Laminate Veneers With and Without Using Galla Chinnesis as Natural Cross Linking and Remineralizing Agent
In teeth requiring laminate veneers with amelogenesis imperfecta Will application of galla chinensis before Bonding of laminate veneers with adhesive resin cement provide better survival rate than conventional Bonding method
- Trial name
- NCT02994862
- Testing
- Galla Chinnesis, Conventional Bonding
- Volunteers
- 16 people
- Sponsor
- Cairo University
Amelogenesis Imperfecta, Dentinogenesis Imperfecta
Non-syndromic Inherited Anomalies of Mineralized Tooth Tissues: a Whole Exome Study to Identify New Pathogenic Variants
ExoDent specifically aims to discover new genes and new mutations causing isolated amelogenesis imperfecta (AI) and dentinogenesis imperfecta (DI) and other dentin anomalies.
- Conditions
- Amelogenesis Imperfecta, Dentinogenesis Imperfecta, Dentin Anomalies
- Trial name
- EXODENT (NCT03810859)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Enamel Renal Syndrome
Renal and Vascular Phenotypic Characterization of Patients With Enamel Renal Syndrome Due to a Pathogenic Variant of the FAM20A Gene and Pathophysiological Study of Ectopic Calcifications
In the research, the investigators will characterize the renal and vascular damage and look for factors favoring the formation of calcification induced by enamel renal syndrome.
- Trial name
- FAM-Cal (NCT07285421)
- Testing
- urinary proteome, urinary metabolome, Evaluation of plasma mineralization factors
- Where
- 2 sites in France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Amelogenesis Imperfecta, Dental Age Estimation
Dental Age Estimation by Different Methods in Patients With Amelogenesis Imperfecta
The aim of this study is to investigate whether there is a significant difference in dental age between children with amelogenesis imperfecta (AI) and healthy controls using Cameriere European formula and London Atlas.
- Trial name
- NCT05343247
- Testing
- Cameriere method, London Atlas method
- Where
- Turkey (Türkiye)
- Volunteers
- 416 people
- Sponsor
- Istanbul University
Amelogenesis Imperfecta, Dental Fluoroses
Colorimetric, Ultra-structural and Elemental Comparison of Dental Enamel Defects
The study focuses on the analysis of enamel defects grouping together hypomineralization and hypoplasia. It focuses on 3 very characteristic enamel pathologies that are most often encountered in dental consultations: Molar…
- Conditions
- Amelogenesis Imperfecta, Dental Fluoroses, Hypomineralization Molar Incisor
- Trial name
- COLOEMAIL (NCT04704089)
- Testing
- spectrophotometer, Biological (protein analysis by western blot or mass spectrometry of matrix proteins), structural (electron microscopy) and physico-chemical analyses
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Amelogenesis Imperfecta
Amelogenesis Imperfecta
Amelogenesis Imperfecta (AI) are a heterogeneous group of rare genetic diseases transmitted according to various mode of inheritance (X-linked, autosomal dominant, autosomal recessive) affecting the formation/mineralization of…
- Trial name
- NCT01746121
- Testing
- Salivary and blood sampling, as part of routine care. Collection of exfoliated teeth.
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Strasbourg, France