Clinical trials: Ametropia
Ametropia
Evaluation of Investigational (Frequent Replacement) FRP Lens for Daily Wear
The purpose of the study is to compare the investigational contact lens to a marketed contact lens. The study results were not used for design validation of investigational contact lens,
- Trial name
- NCT02362724
- Testing
- Sapphire, Pearl
- Where
- 6 sites in United States
- Volunteers
- 89 people
- Sponsor
- CooperVision, Inc.
Ametropia
The Effects of Contact Lenses With Experimental Dye on Visual Function
This is a single-site, two-visit, contralateral, non-dispensing, randomized, controlled and subject-masked study to measure potential benefits of the new UV blocker.
- Trial name
- NCT03556579
- Testing
- senofilcon A with new UV blocker, senofilcon A
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ametropia, Myopia
Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Toric Contact Lenses
The primary objective of this study is to evaluate the axis orientation of LID226397 toric contact lenses.
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT05959200
- Testing
- Serafilcon A toric contact lenses, Senofilcon A toric contact lenses, CLEAR CARE
- Where
- 7 sites in United States
- Volunteers
- 92 people
- Sponsor
- Alcon Research
Ametropia
Clinical Evaluation of Two Daily Disposable Lenses in Sphere Design
This was a single-blind, interventional, prospective, direct refit, bilateral wear, fixed-sequence crossover study.
- Trial name
- NCT05516082
- Testing
- Lens A, Lens B
- Where
- Mexico
- Volunteers
- 41 people
- Sponsor
- CooperVision, Inc.
Refractive Ametropia
The Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses
The purpose of this study is to assess the clinical performance of two reusable silicone hydrogel contact lenses when worn on a daily wear basis.
- Trial name
- NCT05766787
- Testing
- Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
- Where
- 15 sites in United States
- Volunteers
- 190 people
- Sponsor
- Alcon Research
Refractive Errors, Ametropia
Clinical Biocompatibility Evaluation of Contact Lens Coatings
The primary objective is to evaluate corneal staining observed after 2 hours of wear with contact lenses with investigational coating against PureVision™ lenses, all pre-cycled with OPTI-FREE® RepleniSH® multi-purpose…
- Trial name
- NCT03034928
- Testing
- Contact lens with investigational coating 1, Balafilcon A contact lens, OPTI-FREE® RepleniSH® MPDS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Alcon Research
Refractive Ametropia
Evaluation of the Performance of Two Contact Lenses Compared to a Marketed Lens
This study will serve to evaluate and compare the performance of two new lenses to a marketed lens.
- Trial name
- NCT01484028
- Testing
- etafilcon A control lens (1DM), etafilcon A with print and PVP for light eyes (EALE), etafilcon A with print and PVP for dark eyes (EADE)
- Where
- 15 sites in United States
- Volunteers
- 275 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ametropia
Evaluation of Enfilcon A Soft Contact Lens When Compared to Galyfilcon A Soft Contact Lens
The primary objective of thes study is to confirm that the ocular response to the Test lenses are similar to those of the Control lenses when used in a 1 week planned replacement, daily wear modality over a 1-month period.
- Trial name
- NCT01706770
- Testing
- enfilcon A, galyfilcon A
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Ametropia
Clinical Evaluation of a Manufacturing Process for a Frequent Replacement Silicone Hydrogel Multifocal Contact Lens
The purpose of this clinical trial was to evaluate the clinical performance of a manufacturing process on a frequent replacement multifocal contact lens.
- Trial name
- NCT05765227
- Testing
- Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, Hydrogen peroxide-based cleaning and disinfection system
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Alcon Research
Ametropia
Comparison of Two Toric Contact Lenses on Current Toric Wearers
The purpose of this study is to evaluate and compare the clinical performance of two toric contact lenses amongst 110 subjects, 2-week, single masked (subject), daily wear, randomized, bilateral, crossover study; 4 weeks…
- Trial name
- NCT00639379
- Testing
- senofilcon A toric, alphafilcon A toric
- Where
- 7 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Ametropia
Clinical Evaluation of the Safety and Efficacy of a New Multifocal Contact Lens
The purpose of this study was to demonstrate substantial equivalence of the new DAILIES® AquaComfort Plus® Multifocal (DACP MF) contact lens to the commercially available Focus® DAILIES® Progressives (FDP) contact lens.
- Conditions
- Myopia, Ametropia, Presbyopia, Refractive Error
- Trial name
- NCT01797783
- Testing
- Nelfilcon A multifocal contact lens with comfort additive, Nelfilcon A multifocal contact lens
- Volunteers
- 83 people
- Sponsor
- Alcon Research
Refractive Errors, Ametropia
Clinical Comparison of Two Daily Wear Frequent Replacement Silicone Hydrogel Soft Contact Lenses
The primary objective of this study is to evaluate the overall performance of an investigational silicone hydrogel lens when compared to ACUVUE OASYS® with HYDRACLEAR® PLUS (AOHP).
- Trial name
- NCT04532099
- Testing
- Lehfilcon A contact lenses, Senofilcon A contact lenses, Comfilcon A contact lenses
- Where
- 4 sites in United States
- Volunteers
- 132 people
- Sponsor
- Alcon Research
Ametropia
Evaluation of the Performance of Non-molded Soft Contact Lenses
To evaluate the performance of the study soft lens for vision, comfort, physiology and lens surface properties.
- Trial name
- NCT00371787
- Testing
- Soft contact lens
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Refractive Ametropia
A Study to Evaluate the Safety and Effectiveness of a Contact Lens Cleaning and Disinfecting Solution
Approximately 340 participants (680 eyes) will be enrolled in this three-month, two-arm, 1:1 randomized, parallel-group, bilateral, double-masked study at approximately 22 investigative sites in the United States.
- Trial name
- NCT05565937
- Testing
- BL-3100-NBR03 multi-purpose solution, renu® Advanced Formula multi-purpose solution
- Where
- 19 sites in United States
- Volunteers
- 295 people
- Sponsor
- Bausch & Lomb Incorporated
Ametropia, Astigmatism
Comparison of Clinical Performance of Two Monthly Replacement Toric Soft Contact Lenses
The purpose of this study is to assess the clinical performance of TOTAL30 for Astigmatism (T30fA) soft contact lenses with Biofinity Toric soft contact lenses.
- Trial name
- NCT06165627
- Testing
- Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
- Where
- 5 sites in United States
- Volunteers
- 67 people
- Sponsor
- Alcon Research
Ametropia
The Clinical Comparison of Somofilcon A 1 Day and Nelfilcon A Daily Disposable Contact Lenses
This subject-masked, randomized, bilateral crossover study will compare the clinical performance and subjective acceptance of the somofilcon A 1 day soft contact lens with the nelfilcon A daily disposable lens when used on a…
- Trial name
- NCT04067141
- Testing
- somofilcon A, nelfilcon A
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- CooperVision, Inc.
Ametropia
Dispensing Study for the Phenacite Project
Dispensing Study for the Phenacite Project. The investigational test lens was not the final optical design and the study was not used for design validation.
- Trial name
- NCT02436005
- Testing
- Phenacite, comfilcon A
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- CooperVision, Inc.
Refractive Ametropia, Myopia
Comparison of Two Daily Disposable Lenses
The purpose of this study was to compare the clinical performance of the new DAILIES® AquaComfort PLUS® FreshTech (DACP FreshTech) contact lenses to an already marketed daily disposable contact lens, DAILIES® AquaComfort PLUS®…
- Trial name
- NCT04013789
- Testing
- DACP FreshTech contact lenses, DACP contact lenses
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Alcon Research
Ametropia
Performance of Toric Hydrogel Lenses Following A Refit With Toric Silicone Hydrogel Lenses for 1 Month
The aim of this prospective study is to evaluate the clinical performance of habitual wearers of methafilcon A toric lenses after a refit with fanfilcon A toric lenses for 1-month of daily wear.
- Trial name
- NCT03835221
- Testing
- methafilcon A toric contact lenses, fanfilcon A toric contact lenses
- Where
- Mexico
- Volunteers
- 43 people
- Sponsor
- CooperVision, Inc.
Astigmatism, Ametropia
Clinical Comparison of Two Daily Disposable Toric Soft Contact Lenses
The primary purpose of this study is to demonstrate noninferiority in the visual acuity at distance when wearing PRECISION1™ for Astigmatism (P1fA) soft contact lenses compared to another commercially available, soft toric…
- Conditions
- Astigmatism, Ametropia, Myopia
- Trial name
- NCT05483127
- Testing
- Verofilcon A toric soft contact lenses, Stenfilcon A toric soft contact lenses
- Where
- 11 sites in United States
- Volunteers
- 153 people
- Sponsor
- Alcon Research