Clinical trials: Amino Acids, Essential
Bioavailability of Amino Acids
Amino Acids in the Blood After Eating Yoghurt and Milk Proteins
Participants will visit the study site twice in a fasting state. Participants asked to consume one of the two study products in a random order. Participants will consume one serving of the study product (T = 0 minutes).
- Trial name
- NutraFerm2 (NCT07243730)
- Testing
- Full fat yogurt (fermented), Generic full fat pasteurized milk (non-fermented)
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Healthy
Effect of Amino Acid on Muscle Damage
The primary objective is to determine the impact of essential amino acids on integrated muscle protein synthesis over 4 days after resistance exercise.
- Trial name
- NCT03319147
- Testing
- Active
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Sarcopenia
Nutritional and Contractile Regulation of Muscle Growth
Muscle wasting, which involves the loss of muscle tissue, is common in many conditions, such as cancer, AIDS, trauma, kidney failure, bone fracture, and sepsis.
- Trial name
- NCT00891696
- Testing
- Rapamycin, Amino acid supplementation, Low-intensity resistance exercise
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Weight Loss
Nutritional Stimulation of Muscle Protein Synthesis and Metabolic Rate After Bariatric Surgery
Bariatric surgery is an effective treatment for severe obesity but results in loss of muscle mass. The investigators will test the hypothesis that consumption of an Essential Amino Acid-based nutritional formulation will maintain…
- Trial name
- NCT04751916
- Testing
- Essential Amino Acid Protein Supplement, Beneprotein®
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Anterior Cruciate Ligament Reconstruction, Muscular Atrophy
Nutritional Intervention to Enhance Recovery After Arthroscopic Knee Surgery in Adults
Loss of skeletal muscle mass (atrophy) and strength in the lower limb are consequences of elective knee surgery as result of prolonged disuse from limb immobilization and impaired mobility, as well as pathophysiological trauma.
- Trial name
- NCT06233825
- Testing
- Omega-3 Fatty Acids and Essential Amino Acids, Safflower Oil and Non-Essential Amino Acids
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Chris McGlory, PhD
Covid19
Essential Amino Acid Supplementation in Older Adult COVID-19 Patients
A 4-week treatment of essential amino acids or placebo to participants with: 1) negative COVID-19 test with exposure, or 2) positive COVID-19 test and no or mild symptoms. The study team will measure change in symptoms.
- Trial name
- NCT04816071
- Testing
- Essential amino acids, Maltodextrin
- Where
- United States
- Sponsor
- University of Arkansas
Military Operational Stress Reaction, Malnutrition (Calorie)
Physiological Response to Protein and Energy-enhanced Food Products During Winter Military Training
Soldiers commonly lose muscle mass during training and combat operations that produce large energy deficits (i.e., calories burned > calories consumed).
- Conditions
- Military Operational Stress Reaction, Malnutrition (Calorie), Weight Loss, Muscle Wasting
- Trial name
- NCT05210205
- Testing
- EAA, Energy Dense, Control
- Where
- Norway
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Protein Deposition
Protein Source on Plasma Amino Acid Concentrations
This study will determine the effect of the same ounce-equivalents of fresh pork versus nuts, beans, and eggs on postprandial plasma essential amino acid availability in adults. Each participant will receive all four treatments.
- Trial name
- NCT03649568
- Testing
- Pork, Egg, Black beans
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Purdue University
Parkinson Disease
Essential Amino Acids and Parkinsons Disease
Parkinson's disease is a neuromuscular disease that is relatively common in elderly that has many potentials symptoms, including a variety of physical features that together reduce quality of life.
- Trial name
- EAAPD (NCT06604065)
- Testing
- AMS2434 (amino acids)
- Sponsor
- University of Arkansas
Refractory Epilepsy, Drug Resistant Epilepsy
Leucine Enriched Essential Amino Acid Powder as an Add-on to a Classic Ketogenic Diet in Refractory Epilepsy
The main purpose of this study is to evaluate the safety and tolerability of a Leucine-Enriched Essential Amino Acid (LEAA) Powder as an add-on to a classic ketogenic diet (KD) in pediatric and adult patients with refractory…
- Trial name
- NCT06387186
- Testing
- Leucine-Enriched Essential Amino Acid powder
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Elizabeth Anne Thiele
Obesity & Overweight
Effect of a Food for Special Medical Purposes on Muscle Mass Preservation During GLP-1 RAs Weight Loss Treatment
This study evaluates whether a Food for Special Medical Purposes (FSMP) can help to preserve appendicular skeletal muscle mass (ASMM) in adults undergoing weight loss treatment with GLP-1 receptor agonists or dual GIP/GLP-1…
- Trial name
- MYO-PRESERVE (NCT07393360)
- Testing
- Myosave®
- Where
- 3 sites in Italy
- Volunteers
- 144 people
- Sponsor
- Pharmanutra S.p.a.
Nutrition Deficiency Due to A Particular Kind of Food
Quality of Protein From the Common Bean
Dietary Protein quality is based on digestion of proteins to amino acids and the bioavailability of the amino acids to maintain good health and body function.
- Trial name
- NCT04118517
- Testing
- Using intrinsically labelled bean protein to assess bioavailability of amino acids in healthy adults
- Where
- Jamaica
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Chronic Kidney Disease, Sarcopenia
Sarcopenia in Chronic Kidney Disease (CKD) Patients
Sarcopenia, or loss of muscle and strength is common in patients with poor kidney function. Although a high protein diet is generally recommended for sarcopenia, patients with poor kidney function are advised to follow a…
- Trial name
- BOOST_CKD (NCT07437053)
- Testing
- Valine, EEA
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Heart Failure, Diastolic
Muscle, Essential Amino Acids, and eXercise in Heart Failure
Half of heart failure patients have preserved ejection fraction (HFpEF). Like patients with reduced ejection fraction (HFrEF), HFpEF patients suffer from exercise intolerance (low VO2max), which reduces physical function, quality…
- Trial name
- MAAX-HF (NCT03312387)
- Testing
- Exercise, Essential Amino Acids
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Arizona State University
Malnutrition Elderly, Protein Malnutrition
The Effect of a Plant-based, Protein-dense Sauce on Essential Amino Acid Concentrations and Gut Fullness in Older Adults
The goal of this clinical trial is to determine whether meals fortified with plant-based high protein sauce (ProSauce) provide better metabolic availability of essential amino acids compared to meals with standard lower-protein…
- Trial name
- ProSauce (NCT06965699)
- Testing
- ProSauce, low-protein sauce
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Stroke Rehabilitation
Effects of Supplementation With Amino Essential Acids on Circulating Albumin Levels in Stroke in Rehabilitation Phase
In addition to its physiological functions, serum albumin plays a role of neuroprotection in cerebrovascular stroke. The circulating levels of albumin may be reduced in patients with stroke due to the presence of a systemic…
- Trial name
- NCT04459091
- Testing
- Amino Essential Acid
- Where
- Italy
- Volunteers
- 125 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Muscle Loss, Muscle Anabolism
Essential Amino Acids Supplementation and Muscle Protein Synthesis
The modern warfighter faces numerous physiological challenges including sleep deprivation, sustained intense physical activity, and caloric restriction, the combined effects of which may result in the loss of lean body mass and…
- Trial name
- NCT01366924
- Testing
- Essential Amino Acids, Endurance exercise
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Lumbar Spinal Stenosis
Targeted Nutritional Supplement After Lumbar Spine Surgery: A Randomized, Placebo-Controlled, Double-Blind Trial
The goal of this clinical trial is to prospectively evaluate the effects of essential amino acid (EAA) supplementation on the volume and structure of the muscles surrounding the spine (paraspinal musculature).
- Trial name
- NCT06579391
- Testing
- Essential amino acids, Alanine
- Where
- United States
- Sponsor
- University of California, Irvine
Crohn Disease
ProteIn Nutrition in Crohn's Disease
Muscles are essential for good quality of life. The investigators have shown that when children with Crohn's disease eat protein, only very little of it enters the muscles, leading to poor muscle growth and fatigue.
- Trial name
- PINC (NCT05572008)
- Testing
- Protein nutrition in paediatric Crohn's disease
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Femoral Fracture, Fragility Fracture
Essential Amino Acid Supplementation for Femoral Fragility Fractures
This trial will evaluate the impact of 4 weeks of postoperative essential amino acid (EAA)-based supplementation on muscle morphology after femoral fragility fracture.
- Conditions
- Femoral Fracture, Fragility Fracture, Muscle Atrophy
- Trial name
- NCT06050668
- Testing
- Essential Amino Acid Supplementation
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Michael C Willey