Clinical trials: Amoxicillin Allergy
Penicillin Allergy
Geisinger Antibiotic Allergy Pilot Program: Assess and Address
This is a prospective non-inferiority study to evaluate penicillin allergy history in patients with reported penicillin allergy, who require penicillin or penicillin-derivative antibiotic during inpatient admission using a…
- Trial name
- GAAP (NCT05464615)
- Testing
- Amoxicillin
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- Geisinger Clinic
Amoxicillin Allergy
Diagnosing Drug Allergy: the T is the Key
The goal of this clinical trial is to validate a newly developed test in the diagnosis of patients with amoxicillin allergy (i.e. T-cell activation test).
- Trial name
- TAT (NCT06409884)
- Testing
- T-cell activation test using intracellular markers
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Allergy Amoxicillin, Beta-lactam Allergy Labels
The Implementation and Impact of an Allergy De-Labeling Program in the Emergency Department
Beta-lactams are the most common antibiotics prescribed to children, including penicillin and amoxicillin. They are usually more effective and have fewer side effects than other ty antibiotics.
- Trial name
- NCT06823154
- Testing
- Amoxicillin, Study questionnaire
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- The Hospital for Sick Children
Pulmonary Tuberculosis
Trial of Faropenem and Cefadroxil (in Combination With Amoxicillin/Clavulanic Acid and Standard TB Drugs) in Patients With Pulmonary Tuberculosis: Measurement of Early Bactericidal Activity and Effects on Novel Biomarkers
This trial aims to determine whether the early bactericidal activity of rifampicin given with faropenem or cefadroxil (each given with amoxicillin/clavulanic acid) is greater than the activity of rifampicin alone in patients with…
- Trial name
- NCT02381470
- Testing
- Faropenem, Amoxicillin/clavulanic acid, Cefadroxil
- Where
- 6 sites in Philippines, Singapore and 1 more
- Volunteers
- 58 people
- Sponsor
- National University Hospital, Singapore
Allergic Reaction, Beta Lactam Adverse Reaction
Investigation of Cross-allergies Between Cefazolin and Amoxicillin With Skin Tests and Provocation Test
Antibiotic prophylaxis in the operating room reduces the frequency of occurrence of surgical site infections (SSI) by preventing bacterial proliferation. The main antibiotic used in all surgery is CEFAZOLINE.
- Trial name
- CEFAZOPE (NCT05605795)
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Bronchitis, Acute, Community-acquired Pneumonia
Multimodal Stewardship Programme to Improve Antibiotic Prescribing for Children With Lower Respiratory Tract Infections
Children with lower respiratory tract infection (LRTI) are still often prescribed antibiotics in ways that depart from national guidelines.
- Conditions
- Bronchitis, Acute, Community-acquired Pneumonia, Respiratory Tract Infections
- Trial name
- PRACTICE-LRTI (NCT07893834)
- Testing
- PRACTICE-LRTI multimodal antimicrobial stewardship programme
- Where
- Finland
- Volunteers
- 50,000 people
- Sponsor
- Tampere University
Penicillin Allergy
Penicillin Allergy Delabeling After a One-Dose Versus Two-Dose Graded Direct Oral Challenge
The goal of this clinical trial is to learn about dosing when testing to see if a penicillin allergy label can be removed from adults that had been labeled as "penicillin-allergic" previously.
- Trial name
- NCT06303128
- Testing
- Amoxicillin 250 MG, Amoxicillin 62.5mg, Amoxicillin 187.5mg
- Where
- United States
- Volunteers
- 380 people
- Sponsor
- James Tarbox, MD
Penicillin Allergy
Oral Penicillin Challenge and Allergy De-labeling in Children
The primary purpose of this study is to investigate the portion of penicillin allergy labels that are not true allergies using oral amoxicillin challenges among pediatric patients.
- Trial name
- NCT05563610
- Testing
- Amoxicillin 500mg
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Phoenix Children's Hospital
Penicillin Allergy
Amoxicillin Challenge for Penicillin Allergy Diagnosis
False diagnosis of penicillin allergy are frequently reported, and have been proven detrimental to patients. Current guidelines for the assessment of drug allergies recommend that penicillin allergy be evaluated first with prick…
- Trial name
- Pen-VIE (NCT03757052)
- Testing
- Penicillin Skin Testing
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Amoxicillin Allergy
Primary Care Amoxicillin Challenge
The purpose of this project is to identify clinic patients reporting penicillin allergy who are low risk for allergic reaction, and then invite them to participate in an oral amoxicillin challenge in their primary office without…
- Trial name
- NCT05165212
- Testing
- Amoxicillin
- Volunteers
- healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
History of IgE Dependent Reaction to a Penicillin Product
Evaluation of Skin Testing Reagents for Penicillin Allergy
A self- or parent-reported history of penicillin allergy excludes approximately 10% of the US population from receiving penicillin (Kerr 1994, Kagy, Blaiss 1998, Solensky et al. 2000, Neugut et al. 2001).
- Trial name
- NCT01818336
- Testing
- Penicillin skin test kit
- Where
- 13 sites in United States
- Volunteers
- 481 people, healthy volunteers welcome
- Sponsor
- AllerQuest LLC