Clinical trials: Amphetamine-Related Disorders
Amphetamine-Related Disorders, Alcohol-Related Disorders
Mephedrone and Alcohol Interactions in Humans
The purposes of this study are 1) to evaluate the pharmacological effects after oral coadministration of mephedrone and alcohol and 2) determine the pharmacokinetics changes of mephedrone and alcohol concentrations after oral…
- Trial name
- NCT02294266
- Testing
- Mephedrone and alcohol, Mephedrone, Alcohol
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Mood Disorder, Substance-Related Disorders
Pharmacological Interaction Between Pindolol and MDMA (3,4-Methylenedioxymethamphetamine)
MDMA (3,4-Methylenedioxymethamphetamine, "Ecstasy") produces tachycardia, hypertension, hyperthermia, and other acute adverse effects. Ecstasy use has also been associated with rare cardio- and cerebrovascular complications.
- Conditions
- Mood Disorder, Substance-Related Disorders, Amphetamine-Related Disorders
- Trial name
- NCT00895804
- Testing
- MDMA, Pindolol
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Amphetamine Addiction
The Novel Addiction Assessment Study in Synthetic Drugs Addiction
The purpose of this research is to develop an objective assessment based on the virtual reality techniques which is used for evaluate addiction severity.
- Trial name
- NCT02950376
- Testing
- DSM-5 +Virtual reality-based addiction assessment system, Virtual reality-based addiction assessment system
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Amphetamine Addiction
Novel Intervention for Amphetamine-type Stimulants Addiction
The repetitive transcranial magnetic stimulation (rTMS) will be used to treat amphetamine-type stimulant (ATS) addiction.
- Trial name
- NCT02713815
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
HIV Infections
Use of Amphetamine-type Stimulants & Its Relationship With HIV Incidence and Antiretroviral Adherence Among MSM and TG
There are two stages in the study. In Stage 1, 2000 Thai MSM, MSW and TGW/TGSW will be screened at the Thai Red Cross Anonymous Clinic (TRCAC) or Besides walk-in clients of TRCAC, potential participants could be referred to TRCAC…
- Trial name
- NCT03198962
- Where
- Thailand
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Cocaine-Related Disorders
Effectiveness of Modafinil and D-amphetamine in Treating Cocaine Dependent Individuals
Cocaine dependence is a major public health problem; an effective primary treatment for cocaine dependent individuals has yet to be found.
- Trial name
- NCT00218062
- Testing
- D-Amphetamine 30mg, D-Amphetamine 60mg, Modafinil 200mg
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Amphetamine Dependence
Dose Response of Mirtazapine to Methamphetamine Induced Interest, Mood Elevation and Reward
The primary purpose of this study is to determine if Mirtazapine will produce a decrease in interest in the drug, a decrease in mood elevation, and/or a decrease in reward when given before methamphetamine compared to placebo.
- Trial name
- NCT00600145
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Virginia
Substance-Related Disorders, Alcohol-Related Disorders
Conflict Between Maternal Autonomy and Child Health in Substance-use
Qualitative project, comprising open-ended semi-structured interviews with healthcare workers, who provide antenatal care to substance-using women.
- Conditions
- Substance-Related Disorders, Alcohol-Related Disorders, Amphetamine-Related Disorders, Inhalant Abuse
- Trial name
- NCT02797990
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Amphetamine Addiction
The Application of Cognitive Rehabilitation Therapy for Amphetamine-type Stimulants Addiction
The computerized cognitive rehabilitation therapy will be used to treat amphetamine-type stimulant (ATS) addiction.
- Trial name
- NCT03318081
- Testing
- cognitive function rehabilitation and bias modification
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Attention Deficit Hyperactivity Disorder, Nicotine Dependence
Attention Deficit Hyperactivity Disorder (ADHD) Smoking Cessation Study
The overall goal of the present project is to investigate whether lisdexamphetamine (LDX; Vyvanse) is an effective adjunct to nicotine replacement therapy (NRT) to promote smoking cessation in patients with comorbid Attention…
- Trial name
- NCT00736255
- Testing
- Transdermal Nicotine Patch, Lis-dexamphetamine (Vyvanse)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Duke University
Amphetamine-Related Disorders
To Assess the Safety and Tolerability of 7.5, 15 and 30 mg of Sublingual Lobeline. - 1
To assess the safety and tolerability of 7.5, 15 and 30 mg of sublingual lobeline.
- Trial name
- NCT00100074
- Testing
- Lobeline
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders
Study to Evaluate the Likeability, Safety, and Abuse Potential of NRP 104 in Adults With Histories of Stimulant Abuse
This research is being done to evaluate if NRP104 is a safe drug. The other purpose is to learn if NRP104 produces a high and any other effects like amphetamine and other stimulant drugs that are abused.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders, Substance-Related Disorders
- Trial name
- NCT00248092
- Testing
- NRP104
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- New River Pharmaceuticals
Cocaine-Related Disorders, Opioid-Related Disorders
Dextroamphetamine as Adjunct in Cocaine/Opiate Dependent Patients - 3
The purpose of this study is to evaluate dextroamphetamine sulfate (sustained release) as an adjunct in concurrent cocaine and opiate dependent patients.
- Trial name
- NCT00000306
- Testing
- Dextroamphetamine
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Healthy Volunteers, Drug Users
A Study to Evaluate the Abuse Potential of EB-1020 Immediate-Release in Healthy Recreational Stimulant Users
This single-center study will be a single-dose, randomized, double-blind, placebo- and active-controlled crossover study with a single inpatient treatment visit.
- Trial name
- NCT02144415
- Testing
- EB-1020 400 mg, EB-1020 800 mg, lisdexamfetamine 150 mg
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders
Safety, Tolerability and Abuse Liability Study of Intravenous NRP104 in Adults With Stimulant Abuse Histories
This research is being done to evaluate if NRP 104 is a safe drug. The other purpose is to learn if NRP104, when injected into a vein, produces a high and any other effects like amphetamine and other stimulant drugs that are…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders, Substance-Related Disorders
- Trial name
- NCT00247572
- Testing
- NRP104
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- New River Pharmaceuticals
Nicotine Dependence
Imaging Extrastriatal Dopamine Release in Tobacco Smokers and Nonsmokers
The goal is to examine sex differences in amphetamine-induced dopamine release in tobacco smokers and nonsmokers.
- Trial name
- NCT02348385
- Testing
- Amphetamine
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Yale University
Bipolar II Disorder
Differential Responses to Drugs and Sweet Tastes
Young adults who exhibit "bipolar phenotype" (BPP), defined as occasional episodes of mood elevation and heightened activity, are at risk for several psychiatric disorders, including problem use of drugs and alcohol.
- Trial name
- HAP (NCT03810703)
- Testing
- d-amphetamine 10 mg oral capsule, d-amphetamine 20 mg oral capsule
- Where
- 2 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Amphetamine-Related Disorders, Amphetamine Abuse
Investigation of Serotonin Neurotransmission in MDMA Users Using Combinated Dexfenfluramine Challenge and PET Imaging
Illicit use of the psychostimulant "Ecstasy" (3,4-methylenedioxymethamphetamine, MDMA) is considered a major public health issue.
- Trial name
- DEXFEN_PET (NCT01296802)
- Testing
- dexfenfluramine
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Substance Withdrawal Syndrome
EA for PAAS: A pRCT
In 2019, around 27 million people worldwide, corresponding to 0.5% of the adult population, have used amphetamine-type stimulants (ATS). More than one-third of these 27 million users of ATS were in East and South-East Asia.
- Trial name
- NCT04917185
- Testing
- Electro-Acupuncture
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Substance Abuse, Intravenous, HIV
Change the Cycle: An RCT to Prevent Injection Initiation
The study will test the efficacy of a hour long, one-on-one, active listening counseling session (called Change the Cycle or CTC) aimed at reducing behaviors among active people who inject drugs (PWID) that research has found to…
- Conditions
- Substance Abuse, Intravenous, HIV, Heroin Dependence, Opioid Dependence
- Trial name
- CTC (NCT02774954)
- Testing
- Change the Cycle
- Where
- 2 sites in United States
- Volunteers
- 979 people, healthy volunteers welcome
- Sponsor
- University of Southern California