Clinical trials: Ampicillin
Open Fracture, Post-Op Wound Infection
Noninferiority Comparison of Prophylactic Open Fracture Antimicrobial Regimens
To demonstrate noninferiority of three different empiric antimicrobial regimens compared to the traditional antimicrobial regimen for the management of grade III open fractures as well as evaluate outcomes among these groups.
- Trial name
- NCT03560232
- Testing
- Ceftriaxone, Ampicillin/sulbactam, Piperacillin/tazobactam
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Mercy Health Ohio
Infection During Hemodialysis
Concentration of Ampicillin / Sulbactam and Amoxicillin / Clavulanic Acid in the Blood During Renal Replacement Therapy in Longterm Renal Replacement Therapy Patients
The study will be conducted to investigate the pharmacokinetics of ampicillin / sulbactam and amoxicillin/clavulanic acid during intermittent haemodialysis.
- Trial name
- NCT02007603
- Testing
- Administration of Amoxicillin / clavulanic acid, Ampicillin / sulbactam, Blooddraws for pharmacokinetic profiling
- Where
- Austria
- Volunteers
- 16 people
- Sponsor
- Medical University of Vienna
Intra-abdominal Infection
A Comparative Study of Ampicillin/Sulbactam Versus Moxifloxacin in the Treatment of Complicated Intra-abdominal Infections
On the basis of monotherapy for intra-abdominal infection, the investigators are conducting this study to identify the difference of drug efficacy between ampicillin/sulbactam and moxifloxacin.
- Trial name
- NCT00952796
- Testing
- moxifloxacin, ampicillin/sulbactam
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Infections, Bacterial, Sepsis Bacterial
Therapeutic Options for CRAB
CRAB infections in ICUs are on the rise, leading to higher morbidity, mortality, and healthcare costs due to resistance to most antibiotics, including carbapenems.
- Trial name
- TheraCRAB (NCT06440304)
- Testing
- Fosfomycin, Eravacycline, ampicillin/sulbactam
- Where
- Croatia
- Volunteers
- 108 people
- Sponsor
- Clinical Hospital Centre Zagreb
DYT-1, Dystonia
Ampicillin for DYT-1 Dystonia Motor Symptoms
The purpose of this study is to evaluate if the antibiotic Ampicillin is safe and tolerated in patients that have generalized dystonia caused by the DYT-1 gene mutation, as compared to patients treated with a placebo.
- Trial name
- NCT01433757
- Testing
- Ampicillin, Sugar pill
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Florida
HIV Infections
Antibiotics to Reduce Chorioamnionitis-Related Perinatal HIV Transmission
The purpose of this study is to see if antibiotic drugs given to treat an infection of the uterus during pregnancy can reduce the chances of HIV being passed from an HIV-positive mother to her baby.
- Trial name
- NCT00021671
- Testing
- Erythromycin, Nevirapine, Ampicillin sodium
- Where
- United States
- Volunteers
- 3,720 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pneumonia
Zithromax EV in Community-Acquired Pneumonia (CAP)
The intravenous (IV) regimen containing azithromycin (Zithromax) plus ampicillin-sulbactam is consistent with current guidelines for the treatment of CAP.
- Trial name
- NCT00137007
- Testing
- Azithromycin, Ampicillin/sulbactam
- Volunteers
- 151 people
- Sponsor
- Pfizer
Diabetes Mellitus, Diabetic Foot
Study Evaluating the Safety and Efficacy of Piperacillin/Tazobactam and Ampicillin/Sulbactam in Patients With Diabetic Foot Infections
Phase IV Open-Label Foot Infection Study is being conducted to generate comparative Efficacy and Safety data in Diabetic Inpatients.
- Trial name
- NCT00044746
- Testing
- Piperacillin/Tazobactam
- Volunteers
- 314 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Pregnancy Complications, Infectious, Premature Birth
Azithromycin and Ampicillin for Late PPROM
The goal of this clinical trial is to learn whether adding azithromycin to the standard antibiotic treatment (ampicillin) improves newborn outcomes in women with preterm premature rupture of membranes (PPROM) between 34.0 and…
- Conditions
- Pregnancy Complications, Infectious, Premature Birth, Neonatal Diseases and Abnormalities, Antibiotic Prophylaxis
- Trial name
- ALPRO (NCT07183462)
- Testing
- Intravenous Ampicillin followed by Oral Amoxicillin, Ampicillin/Amoxicillin plus single-dose PO Azithromycin
- Where
- Israel
- Volunteers
- 311 people
- Sponsor
- Sheba Medical Center
Esophageal Cancer
Evaluation of Polyflex Stenting in Esophageal Cancer Patients
To evaluate the effectiveness of an esophageal stent as a way to maintain nutrition during radiation and/or chemotherapy treatment.
- Trial name
- NCT00727376
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Louisville
Pneumonia, Aspiration, Lung Abscess
BAY12-8039, iv/Oral Pulmonary Abscess/Aspiration Pneumonia
The purpose of this trial is to determine the efficacy and safety of Moxifloxacin in comparison to Sulbactam/Ampicillin in the treatment of pulmonary abscesses and aspiration pneumonia.
- Trial name
- NCT01045902
- Testing
- Avelox (Moxifloxacin, BAY12-8039), Sulbactam/Ampicillin
- Where
- 15 sites in Germany
- Volunteers
- 139 people
- Sponsor
- Bayer
Breast Cancer
The Efficacy of Prophylactic Antibiotic Administration During Breast Cancer Surgery in Overweight Patients.
This is a single center trial to compare the rate of surgical site infection (SSI) in normal (BMI equal to or less than 25; Control Group)) and overweight (BMI over 25) women who are undergoing breast cancer surgery.
- Trial name
- NCT00356148
- Testing
- Ampicillin/Sulbactam
- Where
- Turkey (Türkiye)
- Volunteers
- 372 people
- Sponsor
- Marmara University
Skin Diseases, Bacterial
Study Comparing the Safety and Efficacy of Tigecycline With Ampicillin-Sulbactam or Amoxicillin-Clavulanate to Treat Skin Infections
The purpose of this study is to compare the safety and efficacy of the antibiotic tigecycline with other antibiotics, ampicillin-sulbactam, and amoxicillin-clavulanate in the treatment of a complicated skin and/or skin structure…
- Trial name
- NCT00368537
- Testing
- Tigecycline, ampicillin-sulbactam
- Where
- 57 sites in United States, Canada and 10 more
- Volunteers
- 550 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Positive E Coli Infections
Ampicillin-sulbactam Resistant E.Coli at UPMC
The information collected will optimize the management of patients with gram negative bacteremia. Approximately 300 patients with Gram negative bacteremia are cared for each year at UPMC-P.
- Trial name
- NCT00619580
- Where
- United States
- Sponsor
- University of Pittsburgh