Clinical trials: Amputation Stump
Amputation Stumps, Amputees
Moisture Management Liner Effectiveness Study
The comfort and fit of the residual limb within a prosthetic socket are of primary concern for many amputees. The residual limb is typically covered by non-breathable and non- thermally conductive materials that can create a warm…
- Conditions
- Amputation Stumps, Amputees, Amputation, Lower Limb Deformities, Congenital
- Trial name
- NCT04427007
- Testing
- Moisture Management Liner, Control Liner
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Liberating Technologies, Inc.
Amputation Stumps
A Comparative Analysis Between College Park Sidekick Feet and Conventional Stubby Prosthesis
The purpose of this study is to compare the College Park Sidekicks to conventional stubby prosthetics to investigate their effects on bilateral above-knee-amputee gait velocity, exertion, and balance.
- Trial name
- NCT02921295
- Testing
- Sidekick Stubbies
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Angela DeCandia
Appendicitis, Surgery
Closure of the Appendix Stump in Laparoscopic Appendectomy
Aimed to the study evaluate the superiority of intracorporal sutures and Hem-o-lok clips in terms of efficiency.
- Trial name
- NCT03930667
- Testing
- clips, knotting
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Orhan Üreyen
Pancreatic Fistula, Distal Pancreatectomy Complications
An Evaluation of a New Technique Utilizing a Biologic Glue and Tissue Patch to Seal the Cut Edge of the Pancreas Following Removal of the Tail of the Pancreas
The purpose of this trial is to determine whether the use of an autologous falciform ligament patch combined with fibrin glue will reduce the rate of pancreatic fistula in patients completing distal pancreatectomy.
- Conditions
- Pancreatic Fistula, Distal Pancreatectomy Complications, Falciform Patch Pancreatic Closure, Fibrin Glue Pancreatic Closure
- Trial name
- NCT00889213
- Testing
- Falciform patch and fibrin glue application, standard pancreatic closure
- Where
- 2 sites in United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Amputation Stump
Characterization of Residual Limb Volume Changes in Transfemoral Amputees
This study quantifies residual limb volume fluctuations affecting transfemoral amputees due to the prosthesis doffing, physical activity, and testing time.
- Trial name
- NCT04709367
- Testing
- 3D optical scan
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro
Other and Unspecified Complications of Amputation Stump
Comparative Outcomes Assessment of the C-Leg With a New Knee Prosthesis
The purpose of this study is to determine if transfemoral amputees of varied etiology will demonstrate increased function, safety and quality of life following accommodation with a new knee prosthesis as compared to their former…
- Trial name
- NCT01473992
- Testing
- Otto Bock C-Leg, Otto Bock Genium
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Jason Highsmith
Amputation Stumps, Neuroma
Pathophysiology of Post Amputation Pain
The purpose of this study is to see how Post Amputation Pain (PAP) affects the body and brain by using sensory testing (such as pinprick testing), taking pictures of your brain (using a functional magnetic resonance imaging…
- Trial name
- PPAP (NCT01632709)
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Stenoses, Carotid Artery
Selective Versus Routine Shunting in Carotid Endarterectomy Patients
The project involves prospectively randomizing patients to either routine carotid shunting or selective carotid shunting during Carotid endarterectomy (CEA) under general anesthesia (GA) to see the difference in post-op…
- Trial name
- NCT00967486
- Testing
- Carotid endarterectomy with routine shount, Carotid endarterectomy with selective shunt
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
Amputation, Skin Wound
Autologous Volar Fibroblast Injection Into the Stump Site of Amputees
This study is a clinical trial testing the safety and efficacy of volar fibroblast (skin cells from the palm or sole) injections for thickening the epidermal (skin) layer at the stump site in people with below the knee…
- Conditions
- Amputation, Skin Wound, Stem Cell
- Trial name
- NCT03947450
- Testing
- Autologous Skin Fibroblasts
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Amputation Stump
Computational Design, Fabrication, and Evaluation of Optimized Patient-Specific Transtibial Prosthetic Sockets
The overall goal of this study is to further develop and clinically assess a computational and data-driven design and manufacturing framework for mechanical interfaces that quantitatively produces transtibial prosthetic sockets…
- Trial name
- NCT03544853
- Testing
- Prosthetic socket for transtibial amputee
- Where
- 2 sites in United States, Mexico
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Amputation Stumps, Pain
Enriched Autologous Fat Grafting for Treating Pain at Amputation Sites
The objective of this pilot study is to assess the efficacy of minimally invasive autologous fat transfers at the amputation sites and the modulation of pain at the respective sites.
- Trial name
- AMP-5 (NCT01645722)
- Testing
- Procedure/Surgery: Enriched Fat grafting
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Neuroma, Neuroma Amputation
Targeted Reinnervation as a Means to Treat Neuromas Associated With Major Limb Amputation
Subjects are being asked to participate in this study because they have an arm or leg amputation and have developed pain related to a neuroma (an ongoing localized pain related to a cut nerve ending).
- Conditions
- Neuroma, Neuroma Amputation, Pain
- Trial name
- TMR (NCT02205385)
- Testing
- Targeted Muscle Reinnervation, Traction Neurectomy
- Where
- 6 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Amputation, Amputation; Traumatic, Leg, Lower
Socket Cooling Effectiveness Take Home Study
The comfort and fit of the residual limb within a prosthetic socket are of primary concern for many amputees. The residual limb is typically covered by non-breathable and non- thermally conductive materials that can create a warm…
- Conditions
- Amputation, Amputation; Traumatic, Leg, Lower, Amputation Stump, Limb; Absence, Congenital, Lower
- Trial name
- NCT04484805
- Testing
- ICE Condition
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Liberating Technologies, Inc.
Appendicitis
Polymer Clips Versus Endoloops for Closure of the Appendiceal Stump During Emergency Laparoscopic Appendicectomy
The investigators propose a study to compare two methods of closing the stump of the appendix during an emergency excision of the appendix using a keyhole approach.
- Trial name
- PECAS (NCT02726152)
- Testing
- Polymer clips for closure of the appendiceal stump, Endoloops for closure of the appendiceal stump
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Health Service, United Kingdom
Distal Pancreatic Resections
Pancreatic Stump Closure After Distal Pancreatic Resection
The aim of this study is to investigate whether finnish binding pancreatico-jejunal anastomosis is feasible and prevents the risk for post operative pancreatic fistula after distal pancreeatectomy.
- Trial name
- NCT02113046
- Testing
- pancreatico-jejunal anastomosis, traditional anastomosis
- Where
- Finland
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Lower Limb Amputation Above Knee (Injury)
Analyzing Stump-socket Interface Pressure to Improve Gait in Above-knee Amputee
This study aims at evaluating the relation between quality of the interface between the stump and the prosthesis, and the quality of gait in above-knee amputees.
- Trial name
- NCT01848964
- Testing
- Clinical and instrumented measurements
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Phantom Limb, Motor Activity
The Effects of Targeted Phantom Motor Execution on Phantom Limb Control
Lower limb amputations account for more than 85% of all amputations. In Canada, it has been reported that transtibial amputation (TTA) is the most common level of amputation.
- Conditions
- Phantom Limb, Motor Activity, Amputation Stump, Amputation
- Trial name
- NCT05247827
- Testing
- Targeted phantom limb motor execution (exercise)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan