Clinical trials: Anaemia Postoperative
Anemia
Efficiency of Patient Blood Management Protocol in Gynecological Surgery Department (PERIOPESGYNECO)
Perioperative anemia is associated with higher risk of red blood cell transfusion, higher rates of morbimortality and lower quality of postoperative recovery.
- Trial name
- PERIOPESGYNECO (NCT06493435)
- Volunteers
- 160 people
- Sponsor
- University Hospital, Angers
Anemia, Knee Arthropathy
Effect of IV Iron Isomaltoside on Postoperative Anemia in Total Knee Arthroplasty Patients
Postoperative anemia is a frequent complication after total knee arthroplasty, with an incidence of 87%. Iron supplementation is known to be effective in treatment and prevention of postoperative anemia.
- Trial name
- NCT03470649
- Testing
- Iron Isomaltoside 1000
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Anemia, Colorectal Neoplasm
IVICA: Intravenous Iron in Colorectal Cancer Associated Anaemia
116 eligible patients with confirmed non-metastatic colorectal adenocarcinoma and anemia will be randomized to receive either oral ferrous sulphate (control) or intravenous ferric carboxymaltose (intervention).
- Trial name
- IVICA (NCT01701310)
- Testing
- Ferric carboxymaltose, Ferrous Sulphate
- Where
- 8 sites in United Kingdom
- Volunteers
- 116 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Atherosclerosis, Anemia
The Transfusion Triggers in Vascular Surgery Trial
BACKGROUND Vascular surgical patients often receive red blood cell (RBC) transfusions in the peri-operative period RBC transfusion may lead to improved outcome but on the other hand the intervention may be harmful Danish Health…
- Conditions
- Atherosclerosis, Anemia, Aortic Aneurysm, Abdominal, Arterial Occlusive Diseases
- Trial name
- TV (NCT02465125)
- Testing
- red blood cell transfusion
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- Naestved Hospital
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Iron Deficiency Anemia
Intravenous Iron to Treat Postoperative Anemia in Older Cardiac Surgery Patients
Postoperative anemia is common in cardiac surgery with cardiopulmonary bypass. Iron deficiency delays the recovery from postoperative anemia and may negatively affect the postoperative trajectory of cardiac surgery patients.
- Trial name
- AGE-ANEMIA (NCT04913649)
- Testing
- Ferric Derisomaltose 100 MG/ML, Sodium chloride
- Where
- 2 sites in Netherlands
- Volunteers
- 310 people
- Sponsor
- dr. P. Noordzij
Anemia, Surgery
Preoperative Monoferric for Abdominal Surgery
Although there are multiple formulations of intravenous (IV) iron to choose from, a one-time dose of Monoferric would make it more feasible to integrate it in the perioperative pathway given an often-limited time between…
- Trial name
- NCT05258825
- Testing
- Monoferric
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Brigham and Women's Hospital
Acute Posthemorrhagic Anemia
Study to Evaluate Efficacy and Safety of BGE-117 in Moderately to Severely Anemic Older Individuals After Major Hip Surgery
The purpose of this study is to explore the safety and tolerability of BGE-117 and gain information on the effectiveness of different doses when given to patients 65 years or older with moderate to severe anemia following major…
- Trial name
- NCT05152641
- Testing
- BGE-117, 4mg, Ferrous Sulfate, BGE-117, 12mg
- Where
- Australia
- Sponsor
- BioAge Labs, Inc.
Postoperative Anemia, Osteoarthritis, Knee
Comparing Intravenous and Oral Iron in Postoperative Anemia
Postoperative anaemia are common in patients undergoing major orthopaedic surgery. The main consequence of perioperative anaemia is an increased risk of red blood cell (RBC) transfusions.
- Trial name
- NCT01913808
- Testing
- Ferric carboxymaltose, ferrous glycine sulphate
- Where
- Spain
- Volunteers
- 122 people
- Sponsor
- Parc de Salut Mar
POCD, Anemia
The Impact of Perioperative Transfusion on Postoperative Cognitive Dysfunction
Although blood transfusion is a representative treatment for acute anemia due to blood loss during surgery, it is also a powerful risk factor for postoperative cognitive dysfunction.
- Conditions
- POCD, Anemia, Transfusion
- Trial name
- NCT04155489
- Testing
- blood transfusion
- Where
- South Korea
- Volunteers
- 148 people
- Sponsor
- Gangnam Severance Hospital
Anemia, Bariatric Surgery
The Impact of Preoperative Anemia on Postoperative Anemia and Related Nutrient Abnormalities After Bariatric Surgery
This study aims to assess the impact of preoperative anemia status on anemia and related nutrient abnormalities 1 year after bariatric surgery.
- Trial name
- NCT06218953
- Where
- China
- Volunteers
- 400 people
- Sponsor
- China-Japan Friendship Hospital
Postoperative Anemia
Association Between Erythroferron and Perioperative Hemoglobin Levels in Patient Undergoing Heart Valve Surgery
In patients undergoing cardiac surgery, perioperative anemia is an important factor in surgical recovery. In addition to the low preoperative hemoglobin level, the delayed recovery of the postoperative hemoglobin level is an…
- Trial name
- NCT05384054
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Yonsei University
Gastric Cancer (GC), Iron Deficiency Anemia (IDA)
Ferric Carboxymaltose Versus Iron Sucrose for Iron Deficiency Anemia After Radical Gastrectomy for Gastric Cancer
This is a multicenter, open-label, randomized controlled trial. A total of 160 patients with iron-deficiency anemia after radical gastrectomy for gastric cancer will be enrolled and randomly assigned in a 1:1 ratio.
- Conditions
- Gastric Cancer (GC), Iron Deficiency Anemia (IDA), Post-Operative Anemia, Radical Gastrectomy
- Trial name
- IRIS (NCT07772453)
- Testing
- Ferric Carboxymaltose (FCM), Iron Sucrose.
- Volunteers
- 160 people
- Sponsor
- Zhaojian Niu,MD
Iron Deficiency Anemia
Postoperative i.v. Iron Substitution in Patients With Diagnosed Iron Deficiency
Iron deficiency anaemia (IDA) in postoperative patients with confirmed preoperative iron deficiency (ID) in a population with planned major surgery who need fast replenishment of iron as judged by the treating physician will be…
- Trial name
- IDA-II (NCT03817957)
- Testing
- Polyglucoferron, Ferric carboxymaltose, Ferrous Sulfate
- Where
- Germany
- Volunteers
- 187 people
- Sponsor
- Prof. Dr. Frank Behrens
Coronary Artery Occlusive Disease
The Effect of Tranexamic Acid on Postoperative Blood Loss and Coagulation in Patients With Preoperative Anemia Undergoing Off-Pump Coronary Artery Bypass Graft; Double Blind Randomized Control Study
The Effect of Tranexamic Acid on Postoperative Blood loss and Coagulation in Patients with Preoperative Anemia Undergoing Off-Pump Coronary Artery Bypass Graft; double blind randomized control study.
- Trial name
- NCT01067638
- Testing
- Tranexamic Acid
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Yonsei University
Anemia After Surgery
Association of Postoperative Anaemia With Patient-centred Outcomes
Primary aim - To investigate the relationship between postoperative anaemia and patient-centred outcomes after major abdominal surgery.
- Trial name
- NCT04978285
- Testing
- Anemia
- Where
- Australia
- Volunteers
- 3,000 people
- Sponsor
- Bayside Health
Sickle Cell Disease
Is the Preoperative Preparation of Sickle Cell Patients Optimal: Assessment of Practices and Post-operative Complications
Children with sickle cell disease systematically receive a transfusion 2 to 5 days before scheduled surgery (with the exception of minor surgeries) in order to avoid post-operative complications of which the vaso-occlusive crisis…
- Trial name
- NCT04264871
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- Queen Fabiola Children's University Hospital
Hip Arthropathy, Malnutrition; Anemia
Nutritional Status and Its Modifications After Hip Replacement
Data literature lacks of evidence concerning the variation of the nutritional status in patients undergoing hip surgery, thus preventing an effective application a nutritional support program.
- Conditions
- Hip Arthropathy, Malnutrition; Anemia, Frail Elderly Syndrome
- Trial name
- NCT03981354
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Postoperative Anaemia
The Use of Iron Therapy for Patients With Anemia After Caesarean Section
The purpose of this study is to determine whether oral or intravenous iron is effective in the treatment of anaemia (iron-poor blood) after caesarean section.
- Trial name
- VITAPOP (NCT01975272)
- Testing
- Ferinject, Ferrous fumarate
- Where
- 2 sites in Netherlands
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Total Knee Arthroplasty
Accelerated Recovery for Total Knee Replacement Surgery With Preoperative Intravenous Iron Combined With Human Erythropoietin for Rapid Hematopoietic Mobilization to Prevent Postoperative Anemia
This study is a randomized, placebo-controlled, multicenter research design to investigate the effectiveness and safety of a single-dose intravenous iron combined with HuEPO hematopoietic mobilization before surgery in patients…
- Trial name
- Hematoboost (NCT05911438)
- Testing
- Ferric Derisomaltose Injection (Monoferric) and Human Erythropoietin Injection (EPIAO), Basic Treatment
- Where
- China
- Volunteers
- 419 people
- Sponsor
- West China Hospital