Clinical trials: Anaesthesia
OSAHS, Gastrointestinal Endoscopy
Observation of Clinical Effect of New Oropharyngeal Airway in Patients With OSHAS During Painless Gastroenteroscopy
the(obstructivesleepapneahypoapneasyndromeOSAHS) is a kind of to sleep appear periodically in the process of syndrome characterized by partial or complete obstruction of upper respiratory tract.Patients with obstruction during…
- Conditions
- OSAHS, Gastrointestinal Endoscopy, Airway Complication of Anesthesia
- Trial name
- NCT06594380
- Testing
- Group using new oropharyngeal airway (experimental group), Endoscopic bite group (control group)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Jianbo Wu
Anxiety State, Parent
Anxiety Level of Child and Parents During Preoperative Anesthesia Evaluation
1. Appreciation of preoperative anxiety in children is important for the anesthesiologist. 2. Several factors defined to effect the anxiety levels preoperatively in children such as , age, previous medical encounters , education…
- Conditions
- Anxiety State, Parent, Child
- Trial name
- NCT02201680
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Measure Time to First Rescue Analgesia Following Extubation
Opioid Free Anesthesia in Shoulder Arthroscope
The investigators will assess opioid free anesthesia technique as regards effectiveness \& duration of post operative analgesia in shoulder arthroscpe surgeries
- Trial name
- NCT06834854
- Testing
- fentanyl, Lidocaine (drug)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Respiratory Depression
Respiratory Depression in Women With BMI≥30 Underwent Spinal Anesthesia With Intrathecal Morphine in Elective C-section
The study will examine whether there is a difference in the frequencies of respiratory depression among obese women receiving spinal anesthesia combined with opioids compared to women with normal BMI.
- Trial name
- NCT02819661
- Testing
- SOMNOTOUCH RESP, Caesarean section, Spinal anesthesia with intrathecal morphine
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Postoperative Analgesia
Comparison of the Effects of Sacral Erector Spinae Plane Block and Dorsal Penile Block on Postoperative Pain in Circumcision Procedures
Egypt performed circumcision in 2300 BC, although its origin is unknown. Some societies use circumcision for health, whereas others do it for religious and cultural reasons .
- Trial name
- NCT06843070
- Testing
- PENILE BLOCK ARM, SACRAL ESP BLOCK ARM
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Interscalene Block, Erector Spinae Plane Block
Interscalene Block Versus Erector Spinae Plane Block for Shoulder Arthroscopy Anesthesia
The aim of this study is to compare the effectiveness of ESPB versus ISB in anesthesia for shoulder arthroscopy
- Conditions
- Interscalene Block, Erector Spinae Plane Block, Arthroscopy
- Trial name
- NCT05646654
- Testing
- Erector spinae plane block, Interscalene brachial plexus block
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Tanta University
General Anesthesia
Comparison of Conventional Lightwand Intubation Versus Video-laryngoscope Guided Lightwand Intubation in Simulated Cervical Spine-immobilized Patients
Among advanced intubation equipment for difficult intubation, a lighted stylet (lightwand) is a widely used equipment in cervical immobilized patients.
- Trial name
- NCT03169556
- Testing
- Video-laryngoscope guided lightwand, lightwand alone
- Where
- South Korea
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Bariatric Surgical Procedures, Anesthesia and Analgesia
Comparison of Abdominal Plane Blocks in Postoperative Pain Control in Patients Undergoing LSG
The goal of this prospective observational study is compare in terms of efficiency and complications transversus abdominis plane (TAP) and Modified thoracoabdominal plane block-perichondrial approach (M-TAPA) blocks in patients…
- Conditions
- Bariatric Surgical Procedures, Anesthesia and Analgesia, Anesthesia, Regional
- Trial name
- NCT06201546
- Testing
- TAP block group, m-TAPA block group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Pain, Stress
Evaluation Of The Analgesia Nociception Index vs. Surgical Pleth Index Under General And Regional Anaesthesia
There is a lack of sufficient analgesia monitoring apart from surrogate parameters. The analgesia nociception index (ANI) shall be evaluated under general and regional anaesthesia.
- Conditions
- Pain, Stress, Monitoring
- Trial name
- NCT02744573
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Pulpitis
Buffered Versus Conventional Local Anesthesia for Pain and Anxiety Reduction in School-Aged Children With Pulpitis
The objective of this clinical trial is to evaluate whether buffered local anesthesia is more effective than conventional local anesthesia in reducing pain responses in school-aged children requiring dental treatment for…
- Trial name
- NCT07638254
- Testing
- Buffered Lidocaine with Epinephrine, idocaine with Epinephrine (Conventional)
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Postoperative Cognitive Dysfunction
Modafinil to Prevent Postoperative Cognitive Decline
Postoperative cognitive dysfunction is a well-recognized complication of surgery. The aim of the study is to investigate whether cognitive dysfunction is reduced by the use of modafinil as shown by neurocognitive testing.The…
- Trial name
- NCT03914118
- Testing
- Preoperative modafinil + postoperative modafinil
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- The Cooper Health System
Local Anesthesia of the Skin.
Fractional Laser Assisted Delivery of Anesthetics
The purpose of this study is to assess the efficacy of fractional CO2 laser assisted delivery of topically applied anesthetics (articaine hydrochloride 40 mg/ml and epinephrine 10 μg/ml solution and EMLA cream) regarding to…
- Trial name
- NCT02246179
- Testing
- AFXL, AHES, EMLA cream
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Netherlands Institute for Pigment Disorders
Anesthesia, Sedation
A Study Evaluating Drug-Drug Interaction (DDI) Between HSK3486 Injectable Emulsion and Voriconazole Tablets
This is a single-center, open-label, randomized, two-stage, two-way crossover study evaluating the effect of voriconazole on the PK, PD, and safety of HSK3486 in healthy subjects.
- Trial name
- NCT04145583
- Testing
- HSK3486, voriconazole +HSK3486
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Sichuan Haisco Pharmaceutical Group Co., Ltd
Procedural Sedation
Dexmedetomidine and Midazolam Nebulization as Sedation During Cesarean Delivery in Pre-eclampsia
Null hypothesis: There is no difference between the effects of nebulization of dexmedetomidine and midazolam as procedural sedation during cesarean delivery under spinal Anesthesia in pre-eclamptic parturients Alternative…
- Trial name
- NCT04873596
- Testing
- Nebulized dexmedetomidine, Nebulized midazolam
- Where
- Egypt
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Dental Caries
Effectiveness of the Intraligamentary Anesthesia and Inferior Alveolar Nerve Block on Pain During Dental Treatment
Objective: To compare the effectiveness and complications of intraligamentary anesthesia (ILA) with conventional inferior alveolar nerve block (IANB) during injection and dental treatment of mandibular posterior teeth.
- Trial name
- NCT04563351
- Testing
- local anaesthetic techniques
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Metal Staple Removal After Total Knee Replacement
Topical Anesthesia for Removal of Stitches After Total Knee Arthroplasty
Lidocaine patch is a safe and effective topical anesthetic agent for removal of metal staples after total knee replacement
- Trial name
- NCT02812602
- Testing
- Lidocaine patch
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Anesthesia, Anesthesia, Local
Caudal Block Versus Dorsal Penile Nerve Block Plus Ring Block for Pain Management of Different Surgical Techniques of Circumcision in Infants and Children
Circumcision is one of the most commonly performed operations in the pediatric population and is a painful procedure. Circumcision is performed with two popular techniques, Plastibell and conventional dissection method (CDM).
- Conditions
- Anesthesia, Anesthesia, Local, Analgesia, Pediatric ALL
- Trial name
- NCT05233683
- Testing
- Caudal block, Dorsal penile nerve block plus ring block, Circumcision with Plastibell
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Saud University
Other Acute Postoperative Pain
Paracetamol Versus Dipyrone After Pediatric Lower Abdominal Surgery in Children With Spinal Anesthesia
We conducted a prospective, randomized double-blind study to compare the effectiveness of intravenous paracetamol and dipyrone for preventing pain during early postoperative period in school-age children undergoing lower…
- Trial name
- NCT01858402
- Testing
- Paracetamol, Dipyrone
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Baskent University
Pain
Post-operative Pain Management In Patients Undergoing Hullax Valgus Surgery
The purpose of this study is to investigate the efficacy and cost analysis of intravenous fentanyl combined with either local anesthesia infiltration or peroneal nerves block in patients with Hallux Valgus undergoing orthopedic…
- Trial name
- NCT01960595
- Testing
- IV fentanyl PCA, local bupivacaine infiltration and post-OP IV fentanyl PCA, Nerve Blocks and post-OP IV fentanyl PCA
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Pain, Postoperative, Anesthesia
Transversus Abdominal Plane Block at Total Laparoscopic Hysterectomy: Effect on Quality of Recovery
The Transversus Abdominal Plane (TAP) block has been used with good success to decrease postoperative pain following laparatomy.
- Trial name
- TAP (NCT01479270)
- Testing
- TAP Block
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center