Clinical trials: Anaesthesia and Analgesia
Postoperative Nausea and Vomiting (PONV), Gynecological Laparoscopic Surgery
Midazolam Adjunct Therapy for Prevention of PONV in Gynecological Laparoscopy
This randomized controlled trial was conducted to evaluate the efficacy of adding midazolam to standard dual antiemetic prophylaxis with dexamethasone and ondansetron for the prevention of postoperative nausea and vomiting (PONV)…
- Conditions
- Postoperative Nausea and Vomiting (PONV), Gynecological Laparoscopic Surgery, Anesthesia Complications
- Trial name
- MIDOD (NCT07668700)
- Testing
- Midazolam 0.05 mg/kg IV as adjunct to dexamethasone and ondansetron for PONV prevention
- Where
- Pakistan
- Volunteers
- 300 people
- Sponsor
- Hameed Latif Hospital, Lahore
Postoperative Pain
Abdominal Wall Local Anesthesia to Maximize Postoperative Pain Control After Cesarean Delivery
This study has been designed to determine if women undergoing cesarean delivery with spinal anesthesia and routine pain management who also have an additional ultrasound guided transversus abdominis plane (TAP)block using…
- Trial name
- NCT01261637
- Testing
- Ropivicaine
- Where
- Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Regional Anesthesia, Interscalene Block
is There an Alternative to Ultrasound Guided Interscalene Block?
Interscalene brachial plexus block is the gold standard for perioperative pain management in shoulder surgery. However, this technique would have side effects and potential serious complications.
- Conditions
- Regional Anesthesia, Interscalene Block, Shoulder Surgery
- Trial name
- NCT02397330
- Testing
- bupivacaine, ultrasound, morphine
- Volunteers
- 60 people
- Sponsor
- Tunisian Military Hospital
Pain Management
Local Anesthesia for Facial Fractures
The study is a double-blind randomized, placebo controlled trial examining the impact of perioperative bupivacaine nerve block on PACU recovery metrics.
- Trial name
- LAFF (NCT06429501)
- Testing
- Bupivacaine/Epinephrine, Saline
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Washington University School of Medicine
Pain, Postoperative
Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management: A Pilot Study
Overall Aim: To evaluate the feasibility and potential benefits of investigating bilateral continuous erector spinae blocks (BESB) for postoperative pain management in a small cohort of children undergoing surgical sternotomy…
- Trial name
- NCT03936387
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Pain, Postoperative, Lumbar Spine Degeneration
Epidural PCA on Pain Relief After L-spine Surgery
This study aimed to evaluate the effect of epidural patient-controlled analgesia (PCA) on postoperative pain relief after lumbar spine surgeries.
- Conditions
- Pain, Postoperative, Lumbar Spine Degeneration, Analgesia, Patient-Controlled, Epidural Anesthesia
- Trial name
- NCT06316921
- Testing
- Epidural patient-controlled analgesia, Standard postoperative pain management
- Where
- Taiwan
- Volunteers
- 209 people
- Sponsor
- Taipei City Hospital
Pain, Anesthesia
Effects of Anesthetic Technique on NK Cells
The proposed study is a pilot prospective, single-blinded, randomized controlled trial evaluating the effects of two routine, standard-of-care, anesthetic techniques on natural killer cell population size and cytotoxicity in…
- Conditions
- Pain, Anesthesia, Cancer
- Trial name
- NCT02669186
- Testing
- Bupivacaine + Fentanyl, Bupivacaine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Postoperative Pain, Laparoscopic Cholecystectomy
Comparison of Ultrasound-Guided Erector Spinae Plane Block and Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) for Postoperative Analgesia After Laparoscopic Cholecystectomy: A Randomized Controlled Study
This study compared two ultrasound-guided regional anesthesia techniques for pain relief after laparoscopic gallbladder surgery: the modified thoracoabdominal nerve block through a perichondrial approach and the erector spinae…
- Trial name
- NCT07751770
- Testing
- Bilateral Ultrasound-Guided Modified Thoracoabdominal Nerve Block Through Perichondrial Approach, Bilateral Ultrasound-Guided Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Saglik Bilimleri Universitesi
Total Knee Arthroplasty, Post Operative Analgesia
Comparing Postoperative Functional Recovery and Analgesic Efficacy of a Single Shot Sciatic Nerve Block Versus Posterior Capsule/Fat Pad Infiltration of Local Anesthetic for Total Knee Arthroplasty
Many methods of pain relief have been implemented in an attempt to provide safe and effective analgesia for patients following total knee arthroplasty.
- Trial name
- NCT00677261
- Testing
- Sciatic Nerve Block, Posterior capsule infiltration with local anesthetic
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- Sunnybrook Health Sciences Centre
Hip Fracture, Postoperative Pain
Comparison of Meta-PENG and Suprainguinal Fascia Iliaca Plane Block in Hip Fractures
This prospective observational single-center study will compare the effects of ultrasound-guided meta-PENG block and suprainguinal fascia iliaca plane block in patients undergoing hip fracture surgery under spinal anesthesia.
- Conditions
- Hip Fracture, Postoperative Pain, Regional Anesthesia
- Trial name
- META-SIFI (NCT07612761)
- Testing
- Ultrasound-Guided Meta-PENG Block, Ultrasound-Guided Suprainguinal Fascia Iliaca Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Anesthesia and Analgesia
Diaphragmatic Breathing Exercises in Total Knee Arthroplasty Patients
Rationale: While total knee replacements (TKA) are one of the most commonly performed surgical procedures in the United States, this procedure can also be very painful.
- Trial name
- NCT04336579
- Testing
- Diaphragmatic Breathing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Southern California
Postoperative Pain
Sufentanil for Anesthesia Induction in Continuous Remifentanil Anesthesia
The appropriate management of postoperative pain is recognized as an important clinical challenge with implications beyond humanitarian issues.
- Trial name
- SAIRA (NCT01777100)
- Testing
- Sufentanil
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Contraception, Pain, Acute
Empathy Through Pain Control: Buffered Compared to Unbuffered 1% Lidocaine During IUD Placement
The goal of this research study is to learn more about how different uses of a numbing medication might affect pain levels while getting an IUD placed.
- Conditions
- Contraception, Pain, Acute, Anesthesia, Local
- Trial name
- EPIC2 (NCT06974019)
- Testing
- Buffered Lidocaine, Lidocaine 1% Injectable Solution
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
General Anesthesia, Laparoscopic Cholecystectomy
Hypokalemia and Intravenous Patient Controlled Analgesia
The increase in stress hormone level and hyperventilation caused by the postoperative pain may contribute to the development of hypokalemia during postoperative period.
- Trial name
- NCT01269099
- Testing
- IV-PCA, Control
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul Medical Center
Primigravida in Labour Pains
Dosing Strategies for Automated Mandatory Intermittent Boluses Technique for Epidural Labour Analgesia
The purpose of this study is to determine how manipulation of the programmed intermittent time interval and volume influences total drug use, quality of analgesia, and patient satisfaction during maintenance of labor analgesia.
- Trial name
- NCT01205360
- Testing
- Bupivacaine-Fentanyl Mixture
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pravara Institute of Medical Sciences University
Pain, Abortion, Spontaneous
Topic Cervical Anesthesia Plus Paracervical Blockade for Pain Control During Endouterine Manual Aspiration
To compare the effectiveness of lidocaine gel plus paracervical blockade vs. lidocaine gel alone in the management of pain during endouterine manual aspiration.
- Trial name
- NCT04791020
- Testing
- Lidocain topical + paracervical blockade, Lidocaine topical
- Where
- Panama
- Volunteers
- 100 people
- Sponsor
- Saint Thomas Hospital, Panama
Pregnancy
Use of Ultrasound in Obstetric Neuraxial Analgesia and Anesthesia Data Base
This is a data base building project on the use of pre-procedure ultrasound for the performance of labor epidural pain relief and spinal anesthesia for cesarean deliveries.
- Trial name
- NCT01192074
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Pain Control During Intravitreal Injections
Handheld Vibrator Versus Topical Eye Drops as Anesthesia for Intravitreal Injections
Intravitreal injections are an efficient method of delivering therapeutic levels of medications to the posterior segment of the eye. Prior to receiving an injection, there are various methods to provide ocular anesthesia.
- Trial name
- Eyebrator (NCT03079713)
- Testing
- Handheld vibrator triggered during intravitreal injection for wet ARMD, Normal eye esthesiometry with and without vibration, Handheld vibrator not triggered during intravitreal injection for wet ARMD
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Pregnancy
Local Anesthesia and Pain Perception During an Amniocentesis
This study is been designed to answer the question of whether local anesthesia (1% lidocaine) decreases the perception of pain associated with amniocentesis in a randomized double blind placebo controlled manner.
- Trial name
- NCT00583011
- Testing
- Local Anesthesia
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Postoperative Pain
Continuous Pre-uterine Wound Infiltration Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Section
The cesarean section is considered as a painful surgery during the post operative period. Mothers may need to move immediately after the surgery to take care of their babies.
- Trial name
- NCT02279628
- Testing
- Ropivacaine, Morphine
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.