Clinical trials: Anaesthesia and Analgesia
164 Boys for Hypospadias Surgery Under General Anesthesia With Caudal Block
Caudal Dexmedetomidine Analgesia in Pediatrics .
Dexmedetomidine (DEXM) is a highly selective α2-adrenoceptor agonist that has been used increasingly in pediatric anesthesia. This prospective double blinded randomized comparative study is designed to evaluate the analgesic…
- Trial name
- NCT03791879
- Testing
- Caudal dexamedatomidine analgesia
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Mansoura University
Hip Fracture, Postoperative Pain
Comparison of Meta-PENG and Suprainguinal Fascia Iliaca Plane Block in Hip Fractures
This prospective observational single-center study will compare the effects of ultrasound-guided meta-PENG block and suprainguinal fascia iliaca plane block in patients undergoing hip fracture surgery under spinal anesthesia.
- Conditions
- Hip Fracture, Postoperative Pain, Regional Anesthesia
- Trial name
- META-SIFI (NCT07612761)
- Testing
- Ultrasound-Guided Meta-PENG Block, Ultrasound-Guided Suprainguinal Fascia Iliaca Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Nociceptive Pain, Goal-directed Therapy
Nol-Index Guided Remifentanil Analgesia Versus Standard Analgesia During Moderate-to-High Risk Cardiovascular Surgery
This study will investigate the potential of guiding remifentanil analgesia during cardiac and vascular surgery in moderate to high risk patients requiring general anesthesia.
- Conditions
- Nociceptive Pain, Goal-directed Therapy, Hemodynamic Instability, Nol-Index
- Trial name
- NCT04137991
- Testing
- Nol-Index guided analgesia, Standard Analgesia
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Erasme University Hospital
Neuromuscular Block, Residual, Pain Management
Methylprednisolone vs Dexamethasone Interaction With Sugammadex in Pediatric Patients
This randomized controlled trial aims to compare the interaction of methylprednisolone and dexamethasone with sugammadex in pediatric patients undergoing adenoidectomy and/or tonsillectomy.
- Conditions
- Neuromuscular Block, Residual, Pain Management, Postoperative Nausea
- Trial name
- NCT07175623
- Testing
- Methyl Prednisolone (MP), Dexamethasone (0.2 mg/kg), Saline (0.9% NaCl)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Konya City Hospital
Postoperative Pain Management, Video-assisted Thoracoscopic Surgery (VATS)
Minimum Effective Volume of Bupivacaine for Serratus Posterior Superior Intercostal Plane Block in Video-Assisted Thoracoscopic Surgery
This study determined the median effective volume (EV50) of bupivacaine required for the serratus posterior superior intercostal plane (SPSIP) block in patients undergoing video-assisted thoracoscopic surgery (VATS).
- Trial name
- SPSIP-EV50 (NCT07446959)
- Testing
- Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Bursa City Hospital
Epidural; Anesthesia, Headache, Analgesia
Comparison of the Epifaith® Syringe With the Plastic Syringe
The goal of this clinical trial is to compare the efficiency of identifying epidural space with either the Epifaith® syringe or the plastic syringe in parturients.
- Trial name
- NCT06085027
- Testing
- Labor analgesia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Pain, Postoperative, Opioid Use
Spinal Anesthesia and Peri-operative Opioid Consumption in Open Abdominal Prostatectomy
Retrospective analysis to assess the impact of spinal anesthesia on peri-operative opioid consumption during open abdominal prostatectomy.
- Conditions
- Pain, Postoperative, Opioid Use, Analgesia
- Trial name
- SAPOC (NCT03565705)
- Testing
- Open abdominal prostatectomy
- Where
- Germany
- Volunteers
- 636 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Periacetabular Osteotomy, Pain
Postoperative Analgesia With Local Infiltration After Periacetabular Osteotomy
Pain treatment after periacetabular osteotomy is traditionally based on systemic opioids wich have side effects. The purpose of this study is to evaluate the analgetic effect of wound infiltration with local anaesthesia after…
- Trial name
- NCT00815503
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Odense University Hospital
Epidural Anesthesia in Labor and Delivery, Doppler Ultrasound
EPidural's Impact on Contractions and Fetal REsponse
This prospective observational study aims to assess the impact of epidural analgesia (ELA) on uterine contractility, cardiotocography (CTG) patterns, and maternal-fetal hemodynamics in term pregnancies.
- Conditions
- Epidural Anesthesia in Labor and Delivery, Doppler Ultrasound, Uterine Contraction
- Trial name
- EPI-CARE (NCT06860854)
- Testing
- Epidural Analgesia
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland
Postoperative Pain
RCT to Test Regional Anesthesia Effect on Decreased Opiate Use
Examining use of strong pain medication with the use of perioperative anesthetic medications vs no use of the same perioperative medication
- Trial name
- NCT06989866
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Pain on Propofol IV Injection
In Children, Does Using a Synera Patch Decrease Pain When Injecting Propofol at Anesthesia Induction?
The purpose of this study is to evaluate if the Synera Patch (lidocaine/tetracaine patch), used to numb the skin before IV placement, is effective in reducing pain associated with propofol IV administration when inducing general…
- Trial name
- Synera patch (NCT01576770)
- Testing
- lidocaine/tetracaine transdermal patch (NDC 43469-864-01), Gebauer's Ethyl Chloride
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas Health Science Center, Houston
Arthroscopic Shoulder Surgery
Erector Spinae Block Versus Shoulder Periarticular Anesthetic Infiltration for Arthroscopic Shoulder Surgery
Arthroscopic shoulder surgery is a common and minimally invasive procedure utilized for different shoulder pathologies, but it is often associated with moderate to severe postoperative pain that may interfere with patients'…
- Trial name
- NCT03691922
- Testing
- Erector Spinae Plane (ESP) Block, Periarticular Infiltration (PAI)
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- McMaster University
Lung Cancer, Pain, Postoperative
Pain Control After VATS Anatomical Pulmonary Resections
In patients undergoing minimally invasive thoracoscopic surgery (video-assisted thoracoscopic surgery, or VATS), moderate to severe post-operative pain may often be experienced.
- Conditions
- Lung Cancer, Pain, Postoperative, Thoracic Neoplasms
- Trial name
- NCT05993273
- Testing
- Epidural, ESP block, Cryoanalgesia
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- University Hospital Padova
Anterior Ilıac Block, Hernia Surgery
Effect of Anterior Iliac Block on Postoperative Analgesia and Patient Satisfaction in Inguinal Hernia Repair Surgery
Inguinal hernia repair is one of the most commonly performed surgical procedures worldwide and presents challenges in anesthesia selection and postoperative pain management.
- Conditions
- Anterior Ilıac Block, Hernia Surgery, Spinal Anesthesia
- Trial name
- NCT07533383
- Testing
- Anterior Iliac Block, Control Group (A):
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Perioperative Analgesia, Hip Dislocation, Developmental
PENG Block in Comparison With FICB for Hip Reconstruction in Children
The goal of this clinical trial is to test the hypothesis that performing a Pericapsular nerve group (PENG) block allows for more effective analgesia in the perioperative period during reconstructive surgery on the hip in…
- Trial name
- NCT06210503
- Testing
- Pericapcelar group nerve block, Fascia iliaca compartment block
- Where
- Russia
- Volunteers
- 86 people
- Sponsor
- Saint Petersburg State University, Russia
Postoperative Shivering
Dexemedetomidine on Shivering Cesarean Section Under Spinal Anesthesia A Randomized Clinical Trial
Participants will examine dexemedetomidine versus dexamethasone on postoperative shivering after spinal anesthesia for caesarean section
- Trial name
- NCT05952752
- Testing
- giving dexemedetomidine 12 microgram Iv dripping, Dexamethsone IV
- Where
- Egypt
- Volunteers
- 382 people
- Sponsor
- Assiut University
Pain Management, Dexmedetomidine
Dexmedetomidine Different Doses as Adjuvant to Entropy-assisted General Anesthesia During Functional Endoscopy Sinus Surgery.
The aim of work to assess the effect of different doses of Dexmedetomidine when used as an adjuvant to entropy-guided general anesthesia on the intraoperative surgical field quality, inhaled anesthesia consumption and…
- Conditions
- Pain Management, Dexmedetomidine, Anesthesia
- Trial name
- NCT05226325
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 99 people
- Sponsor
- Cairo University
Renal Insufficiency, Chronic, Acute Pain
Efficacy Transverse Abdominal Plane (TAP) Block Renal Transplant Surgery
The objective of this study is to evaluate the efficacy and safety of transverse abdominal plane block in patients undergoing renal transplant surgery.Adult renal transplant recipients will be prospectively randomized to receive…
- Conditions
- Renal Insufficiency, Chronic, Acute Pain, Kidney Transplantation, Anesthesia, Conduction
- Trial name
- NCT03181438
- Testing
- TAP Block, Saline Group
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Federal University of São Paulo
Hip Hemiarthroplasty
Quality Of Recovery After Pericapsular Nerve Group (PENG) Block For Hip Hemiarthroplasty Under Spinal Anesthesia
Patients undergoing hip hemiarthroplasty can benefit significantly from regional anesthesia in terms of pain management and recovery . There is a wide range of regional anesthetic techniques.
- Trial name
- NCT06369948
- Testing
- Pericapsular Nerve Group (PENG) Block, elective hip hemiarthroplasty without receiving a PENG block., bupivacaine 0.5% injection
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Fayoum University Hospital
Intraoperative Analgesia, Postoperative Pain
PECS II Versus ICBN Block Plus SCNB for AV Fistula Creation in CRF Patients
Brachial plexus block (BPB) is often utilized for proximal arm arteriovenous access creation. However, the medial upper arm and axilla are often inadequately anesthetized, as the Intercostobrachial nerve (which provides sensory…
- Trial name
- NCT04988776
- Testing
- ultrasUltrasound-guided Intercostobrachial nerve block supplemental to supraclavicular block with 30 ml 0.25% bupivacaine (15 ml 0.5% bupivacaine will be added to 15 m, ultrasound-guided pectoral nerves block type II supplemental to supraclavicular block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Menoufia University
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