Clinical trials: Anaesthesia and Analgesia
Hip Fractures, Anesthesia
Nurse Led Ultrasound Guided Femoral Nerve Block in the Emergency Department
The aim of this study is to investigate the effects of task shifting from anesthesiologists to special trained nurses performing femoral nerve block (FNB) in patients with hip fracture in the emergency department (ED) at Vestfold…
- Conditions
- Hip Fractures, Anesthesia, Femoral Neck Fractures
- Trial name
- URGENT (NCT04145752)
- Testing
- Nurse-led femoral nerve block
- Where
- Norway
- Volunteers
- 42 people
- Sponsor
- Espen Lindholm
Pain Management, Dental Anxiety
Digital vs. Conventional Anesthesia for Primary Tooth Extractions in Pediatric Patients
This study aims to compare two different techniques of administering dental anesthesia to pediatric patients to determine which method causes less pain and anxiety during procedures like primary tooth extractions.
- Conditions
- Pain Management, Dental Anxiety, Pediatric Dentistry, Dental Anesthesia
- Trial name
- NCT07087028
- Testing
- SleeperOne™, Conventional Infiltration Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ege University
Rupture of Anterior Cruciate Ligament, Infiltration
Local Infiltration Analgesia vs Adductor Canal Block for Analgesia After Anterior Cruciate Ligament Reconstruction
Early rehabilitation after anterior cruciate ligament reconstruction is of paramount importance and requires optimal pain control based on a multimodal concept, including injection of local anaesthetics.
- Conditions
- Rupture of Anterior Cruciate Ligament, Infiltration, Regional Anesthesia Morbidity
- Trial name
- NCT02524652
- Testing
- Ropivacaine 0.5% 20 mLs
- Where
- Switzerland
- Volunteers
- 104 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
RATS Surgery, Thymectomy
Serratus Posterior Superior Intercostal Plane Block in Robotic-Assisted Thymectomy
This study aims to assess the effectiveness of the Serratus Posterior Superior Intercostal Plane Block (SPSIP Block) for postoperative pain control, reducing opioid analgesic consumption, minimizing postoperative respiratory…
- Conditions
- RATS Surgery, Thymectomy, Locoregional Anesthesia, Postoperative Pain Management
- Trial name
- SPRATS (NCT06545409)
- Testing
- Ultrasound-guided Serratus Posterior Superior Intercostal Plane Block performed with 0.25% bupivacaine
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hip Fracture
Fascia Iliaca Compartment Blockade as Analgesia for Hip Fractures in the Acute Phase
To evaluate the analgesic potential of an neural blockade (Fascia iliaca compartment) with local anaesthetics in patients with hip fracture immediately after arrival in the emergency department.
- Trial name
- NCT00162630
- Testing
- Fascia Iliaca Compartment Blockade
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Hvidovre University Hospital
Intracranial Aneurysm, Postoperative Pain
Effect of Bilateral Greater Occipital Nerve Block on Headache After Intracranial Aneurysm Coiling
Postoperative headache is a common complication following endovascular coil embolization of intracranial aneurysms and may increase analgesic requirements, impair patient comfort, and contribute to hemodynamic instability.
- Trial name
- NCT07910864
- Testing
- Ultrasound-Guided Bilateral Greater Occipital Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Konya City Hospital
Mastectomy, Rhomboid Intercostal Block
Effects of Rhomboid Intercostal Block on Postoperative Pain Management and Chronic Pain Incidence in Mastectomies
The goal of this clinical trial is to evaluate the effects of the Rhomboid Intercostal Block (RIB) on postoperative chronic pain prevalence at 3 months (primary outcome) and on acute pain control, total opioid consumption, and…
- Conditions
- Mastectomy, Rhomboid Intercostal Block, Chronic Pain Following Surgical Procedure for Cancer
- Trial name
- NCT06756048
- Testing
- Rhomboid Intercostal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Koç University
Perioperative Analgesia, Hip Replacement, Total
Pericapsular Nerve Group Block Versus Intrathecal Morphine for Analgesia After Total Hip Arthroplasty
The Pericapsular Nerve Group (PENG) block is an effective method for postoperative pain management in patients undergoing primary total hip arthroplasty (THA) via a posterolateral approach.
- Conditions
- Perioperative Analgesia, Hip Replacement, Total, Postoperative Pain, Hip Disease
- Trial name
- NCT07449585
- Testing
- PNEG block, Spinal anesthesia with opioid, Spinal anesthesia without opioid
- Volunteers
- 180 people
- Sponsor
- Medical University of Gdansk
Hernia Abdominal Wall
Remifentanil in Deep vs Moderate Neuromuscular Blocks During Surgical Pleth Index-guided Anesthesia for Laparoscopic Herniorrhaphy
The primary purpose of this study is to compare the remifentanil requirements in deep versus moderate neuromuscular blocks during the surgical pleth index -guided anesthesia in patients undergoing laparoscopic herniorrhaphy.
- Trial name
- NCT04022733
- Testing
- Moderate neuromuscular block, Deep neuromuscular block
- Where
- South Korea
- Volunteers
- 134 people
- Sponsor
- Ajou University School of Medicine
Laparoscopic Cholecystectomy, Postoperative Pain Management
Sensory Analysis and Cutaneous Mapping of Different Regional Anesthesia Techniques
This prospective observational study aims to evaluate and compare the sensory block distribution and regression patterns of two regional anesthesia techniques - External Oblique Plane Block (EOPB) and Serratus Intercostal Plane…
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Pain Management, Regional Anesthesia
- Trial name
- NCT07445854
- Testing
- External Oblique Plane Block (EOPB), Serratus Intercostal Plane Block (SIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Samsun University
Infertility, Anesthesia
The Effect of Music Therapy on Analgesia and Oxidative Stress Parameters
Music has been used in the treatment of patient since the time Plato, Hippocrates and Alpharabius were alive. It is used by music therapists to help patients' social, physical, emotional, psychological and spiritual needs.
- Trial name
- NCT03346031
- Testing
- music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Regional Anesthesia Block, Regional Anesthesia
PENG and LFCN Block Versus FIC Block for Multimodal Analgesia After Total Hip Replacement Surgery: a Retrospective Analysis Focused on Movement (Retro-PvF)
Total hip arthroplasty is a major surgical procedure performed on a growing number of patients. Optimal pain control with limited muscle weakness is paramount for a swift initiation of physical therapy and ambulation, thus…
- Conditions
- Regional Anesthesia Block, Regional Anesthesia, Total Hip Replacement Surgery, Total Hip Arthroplasty \(THA\)
- Trial name
- Retro-PvF (NCT06342102)
- Testing
- PENG + LFCN block, FIC block
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Ospedale Edoardo Bassini
Humans, Anesthetics, Local
MORphine Use in the Fascia Iliaca Compartment Block With UltraSound
Appropriate management of analgesia for proximal femoral fractures is a common problem in the emergency department (ED). Side effects from morphine usage such as nausea, vomiting, respiratory depression, sedation, and obstipation…
- Conditions
- Humans, Anesthetics, Local, Morphine, Pain Management
- Trial name
- MORFICUS (NCT03846102)
- Testing
- Levobupivacaine, Acetaminophen, Morphine
- Where
- Netherlands
- Volunteers
- 55 people
- Sponsor
- Zuyderland Medisch Centrum
Emergence Delirium, Extubation Time
Dexmedetomidine Reduces Emergence Delirium in Children Undergoing Tonsillectomy With Propofol Anesthesia
Dexmedetomidine (DEX) is safe and effective in reducing ED following sevoflurane anesthesia. The investigators intend to study the efficacy of DEX in reducing ED in children undergoing tonsillectomy with and without adenoidectomy…
- Conditions
- Emergence Delirium, Extubation Time, Heart Rate, Postoperative Analgesia
- Trial name
- NCT03131375
- Testing
- Dexmedetomidine, Normal saline, Bispectral index
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Athens General Children's Hospital "Pan. & Aglaia Kyriakou"
Coronary Artery Bypass, Anesthesia, Conduction
Effect of Transversus Thoracic Muscle Plane Block (TTMP) on Analgesia
In this prospective and controlled study, the investigators investigated the effect of transversus thoracic muscle plane block (TTMP) on analgesia in patients who undergo coronary artery bypass graft (CABG) surgery with median…
- Conditions
- Coronary Artery Bypass, Anesthesia, Conduction, Nerve Block, Pain, Postoperative
- Trial name
- NCT06601530
- Testing
- Transversus Thoracic Muscle Plane Block, Tramadol
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain Management
Local Anesthesia for Facial Fractures
The study is a double-blind randomized, placebo controlled trial examining the impact of perioperative bupivacaine nerve block on PACU recovery metrics.
- Trial name
- LAFF (NCT06429501)
- Testing
- Bupivacaine/Epinephrine, Saline
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Washington University School of Medicine
Postoperative Pain, Regional Anesthesia
Postoperative Pain Management in Laparoscopic Cholecystectomies
This study is to demonstrate the effectiveness of external oblique intercostal plane block, a new block method, in the treatment of postoperative pain occurring after laparoscopic cholecystectomy operations, which are frequently…
- Trial name
- NCT06326281
- Testing
- unilateral external oblique intercostal plane block group, unilateral oblique subcostal transversus abdomınıs plane block group, Local anesthetic infiltration group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ankara City Hospital Bilkent
Postoperative Pain, Regional Anesthesia
Comparison of Continuous Fascia Iliaca Compartment Block With Continuous PENG Block in Total Hip Replacement Cases
Adequate pain management after total hip arthroplasty (THA) is crucial for early ambulation and patient satisfaction. However, due to the hip joint's innervation complexity, the optimal regional analgesia technique for THA…
- Conditions
- Postoperative Pain, Regional Anesthesia, Pain Management, Total Hip Arthroplasty
- Trial name
- PENG (NCT06806865)
- Testing
- Periarticular nerve group block (PENG), Continuous supra-inguinal fascia iliaca compartment block (SIFICB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Regional Anesthesia Morbidity, Arthropathy of Hip
PENG and LFCN Block Versus FIC Block for Multimodal Analgesia After Total Hip Replacement Surgery: a Retrospective Analysis
Background: Optimal pain control with limited muscle weakness is paramount for a swift initiation of physical therapy and ambulation.
- Conditions
- Regional Anesthesia Morbidity, Arthropathy of Hip, Hip Arthropathy
- Trial name
- PENG+LFCN-FICB (NCT05916209)
- Testing
- Peripheral nerve blocks
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Ospedale Edoardo Bassini
Labor Pain and to Reduce Pain
Does the Volume of Medication Affect the Success of Labor Epidural Analgesia
The purpose of this study is to evaluate whether changing the volume and concentration of a medication affects the quality of pain relief and the side effects associated with labor epidural analgesia.
- Trial name
- EpiVol (NCT07684365)
- Testing
- administration of bupivacaine 7.5 mg and fentanyl 24 mcg every 40 minutes
- Volunteers
- 70 people
- Sponsor
- Beth Israel Deaconess Medical Center
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