Clinical trials: Anaesthesia and Analgesia
Anesthesiology, Percutaneous Coronary Intervention
Ultrasound-Guided Transversus Abdominis Plan (TAP) Block in Endovascular Cardiac Interventions
Sensory innervation of the femoral region which is the entry point for endovascular cardiac interventions such as coronary angiography,cardiac catheterization and percutaneous coronary intervention is complex.It is thought that…
- Conditions
- Anesthesiology, Percutaneous Coronary Intervention, Cardiac Catheterization, Analgesia
- Trial name
- NCT06576128
- Testing
- ultrasound, parenteral local anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain Relief During Prostate Biopsy
Combined Intravenous Diazepam, Local Periprostatic Nerve Block for Prostate Biopsy
Prostate biopsy under transrectal ultrasound (TRUS) guidance is considered the procedure of choice for diagnosing prostate cancer.
- Trial name
- NCT02935972
- Testing
- Diazepam, Lidocaine 1%, Diazepam and Lidocaine 1%
- Where
- Egypt
- Volunteers
- 336 people
- Sponsor
- Assiut University
Pain, Postoperative
Pre-emptive Local Anaesthesia in Gynecological Laparoscopy
Pre-emptive local anaesthetics are widely used in laparoscopic surgery, but there is no really consistent evidence that it is useful. Studies in the literature have shown contradicting results.
- Trial name
- NCT01677143
- Testing
- Bupivacaine 5mg/ml
- Where
- Norway
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Local Anesthetics, Analgesia
Liposomal vs. Conventional Bupivacaine for Pain Control
The goal of this pilot study is to test the hypothesis that liposomal bupivacaine extends the duration of paravertebral block in patients undergoing radical nephrectomy, achieving improved analgesia compared to conventional…
- Conditions
- Local Anesthetics, Analgesia, Regional Block, Paravertebral Block
- Trial name
- NCT06231355
- Testing
- Performing paravertebral nerve block with lipo-bupivacaine, Performing paravertebral nerve block with bupivacaine
- Where
- China
- Volunteers
- 61 people
- Sponsor
- Peking University First Hospital
Anesthesia Depth Monitoring, Analgesia Assessment
Target-Controlled Infusion (TCI) Effectiveness in Hysteroscopy
This prospective, randomized, observational study aims to evaluate the perioperative anesthetic efficacy of different Target-Controlled Infusion (TCI) models-specifically Minto, Schnider, and Eleveld pharmacokinetic models-in…
- Conditions
- Anesthesia Depth Monitoring, Analgesia Assessment, Perioperative Safety and Recovery, Target Controlled İnfusion
- Trial name
- NCT07023263
- Testing
- Schnider+ Mİnto, Eleveld
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Gazi University
Cesarean Section, Analgesia
Prevalence of Insufficient Analgesia in Caesarean Section Under Neuroaxial Anesthesia (PAICAN)
Pain during caesarean section under neuraxial anesthesia is often underestimated and could be related to perinatal psycholocal disorders.
- Trial name
- PAICAN (NCT06824740)
- Where
- Spain
- Volunteers
- 318 people
- Sponsor
- Parc de Salut Mar
Cesarean Section, Postoperative Pain After Cesarean Section
Nociception Level Index Monitoring During Cesarean Section
This prospective randomized controlled trial evaluated the effect of nociception level (NOL) index-guided intraoperative analgesia on postoperative pain management in patients undergoing elective cesarean section under general…
- Conditions
- Cesarean Section, Postoperative Pain After Cesarean Section, Pain Management
- Trial name
- NOL-CS (NCT07720440)
- Testing
- Nociception Level Index Monitoring, Standard Intraoperative Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Post Operative Pain
Comparison of M-TAPA and TAP Blocks on Postoperative Analgesia in Laparoscopic Appendectomy Surgeries
The goal of this study is to compare the analgesic efficacy of M-TAPA block and TAP block in patients undergoing laparoscopic appendectomy surgeries
- Trial name
- NCT06483581
- Testing
- M-TAPA block with bupivacaine 25%, TAP block with bupivacaine 25%
- Volunteers
- 30 people
- Sponsor
- Cumhuriyet University
Anesthesia, Pain
Surgical Pleth Index (SPI) Versus Standard Clinical Approach Analgesia
The study is aimed at confronting a surgical pleth index based protocol for intraoperative analgesia in a desflurane based general anesthesia for thyroidectomy, versus a standard clinical approach.
- Conditions
- Anesthesia, Pain, Surgery
- Trial name
- SPIDER (NCT03218306)
- Testing
- Surgical Pleth Index, Clinical guidance
- Where
- Italy
- Volunteers
- 198 people
- Sponsor
- University of Cagliari
Total Knee Arthroplasty, Pain Management
Analgesic Efficacy of Preemptive Stepwise Infiltration Anesthesia for Perioperative Analgesia After TKA
This is a single-center prospective cohort study in which patients were evaluated by inclusion and exclusion criteria before total knee arthroplasty (TKA).
- Trial name
- NCT06600815
- Testing
- preemptive stepwise infiltration anaesthesia(PSIA), postoperative local infiltration analgesia(PLIA)
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Distal Radius Fracture
Bier's Block Versus Systemic Analgesia
Background: There are three methods for procedural sedation in upper extremity traumas; systemic, regional and local anesthesia. There is controversy in the literature regarding the method of choice for this purpose.
- Trial name
- NCT03349216
- Testing
- Intravenous Regional Anesthesia, Systemic Analgesia
- Where
- Iran
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Postoperative Analgesia
Transversalis Fascia Plane Block vs Transversus Abdominis Plane Block In Pediatric Surgeries
In this study, the investigators compared ultrasound-guided transversalis fascia plane (TFP) block and transversus abdominis plane (TAP) block on postoperative analgesic effect in pediatric abdominal surgeries
- Trial name
- NCT06530147
- Testing
- Transversalis Fascia Plane Block, Transversus Abdominis Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Kocaeli University
Laparoscopic Cholecystectomy Surgery, Postoperative Pain Management
The Efface of Ketamine vs. Magnesium Sulphate in the Management of Pain After Laparoscopic Cholecystectomy
This prospective interventional study was conducted at Liaquat National Hospital and Medical College to compare the postoperative analgesic effects of ketamine and magnesium sulphate in patients undergoing laparoscopic…
- Trial name
- NCT07248358
- Testing
- IV ketamine 0.5 mg/kg, IV 2mg of Magnesium Sulphate
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Liaquat National Hospital & Medical College
Nephrolithiasis
Postoperative Analgesia Practices After Percutaneous Nephrolithotomy
This prospective observational study aims to evaluate the effectiveness and safety of different postoperative analgesia methods used in patients undergoing percutaneous nephrolithotomy (PCNL).
- Trial name
- NCT07258901
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istinye University
Local Anesthesia, Analgesia
Catheter-over Needle: Outpatient Study
An alternative to general anesthesia - which puts a patient completely to sleep - is regional anesthesia, where local anesthetic is injected under the skin to freeze or 'block' a nerve or set of nerves.
- Trial name
- NCT01522066
- Testing
- Perineural catheter, Single-shot block
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Alberta
Pain, Shoulder Injury
Efficacy of Nerve Blockade Performed Prior to Surgical Intervention Versus Following Surgical Intervention
Nerve blocks, or pain medication injected next to the nerve while patients are asleep, are commonly used for pain management after shoulder surgery and are considered highly effective in decreasing post-operative pain.
- Trial name
- NCT02666118
- Testing
- Preemptive Interscalene Block - Single Shot, Postoperative Interscalene Block- Single Shot, Preemptive Interscalene Block - Catheter
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Anesthesia
Low Dose Dexamethasone to Local Anesthetic in Caudal Analgesia on Healing Process After Orthopaedic Surgery
Addition of dexamethasone to local anesthetics infiltration has been proven to augment postoperative analgesia, prolongs anesthesia time and sometimes reduces the needed dose of local anesthetics and consequently, decreases their…
- Trial name
- NCT05755880
- Testing
- Intrathecal dexamethason
- Volunteers
- 60 people
- Sponsor
- Assiut University
Obesity, Postoperative Pain
OFA vs OBA in Bariatric Surgery
This study compares two different anesthesia techniques in patients with obesity undergoing bariatric surgery: one that includes opioids (OBA), and one that avoids them completely (OFA).
- Conditions
- Obesity, Postoperative Pain, Bariatric Surgery, Opioid-free Anesthesia
- Trial name
- OFA VS OBA1 (NCT07075302)
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Hospital HM Nou Delfos
Regional Anesthesia Success, Pain Monitor During Anesthesia
Comparison of Caudal and Quadratus Lumborum Blocks With Pain Monitoring in Children
Study Type: Prospective, Randomized, Observational Clinical Study Primary Purpose: The primary objective of this study is to compare the analgesic efficacy of caudal block (CB) and quadratus lumborum block (QLB) in children…
- Conditions
- Regional Anesthesia Success, Pain Monitor During Anesthesia, Quadratus Lumborum Nerve Block, Caudal Block for Postoperative Analgesia
- Trial name
- NCT07398573
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ankara Etlik City Hospital
Erector Spinae Plane Block, Lower Extremity Surgery
Regional Anesthesia for Lower Extremity Surgery
In this study, patients who underwent osteosynthesis with plate via standard anterolateral incision due to proximal tibia fracture in the orthopedic clinic within the last year; those who underwent perioperative anesthesia with…
- Conditions
- Erector Spinae Plane Block, Lower Extremity Surgery, Sciatic Nerve Block
- Trial name
- NCT06777953
- Testing
- Erector Spinae (ESP) Block with Lidocaine/Bupivacaine, Popliteal Sciatic Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Haseki Training and Research Hospital
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