Clinical trials: Analgesia, Cesarean
Pain, Postoperative
A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section Pain
the purpose of this study is to compare opioid consumption in morphine equivalents between the groups that received postoperative analgesia with intrathecal morphine versus US guided QL blocks versus US guided QL catheters
- Trial name
- NCT04368364
- Testing
- Intrathecal morphine sulfate (ITM), Bupivacaine hydrochloride, ropivacaine hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Pain, Cesarean Section
Analgesia and Antihyperalgesia of Tramadol and Acetaminophen Per Oral After Caesarean Section
The aim of this study is to evaluate quality of patient-controlled peroral analgesia after cesarian section using the combination of tramadol and acetaminophen.
- Trial name
- NCT00873743
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Pain
Is Paracetamol an Effective Treatment for Chronic Moderate Pain in the Newborn After Operative Vaginal Delivery?
There are many reasons for using a vacuum apparatus or forceps to assist in delivering a baby. The traction and pressure on the baby's head due to the vacuum apparatus or forceps may cause pain and discomfort for some time after…
- Trial name
- NCT00488540
- Testing
- Paracetamol
- Where
- 3 sites in Switzerland
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Cesarean Delivery, Postoperative Analgesia
Intrathecal Morphine vs Transversalis Fascia Plane Block After Cesarean Delivery
This prospective single-center study compares intrathecal morphine and ultrasound-guided bilateral transversalis fascia plane block for postoperative analgesia in patients undergoing elective cesarean delivery under spinal…
- Conditions
- Cesarean Delivery, Postoperative Analgesia, Obstetric Anesthesia
- Trial name
- NCT07374133
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Post-operative Pain Control
Impact of the Number of Opiates Prescribed on Post Cesarean Pain Control
The purpose of this randomized trial is to examine whether the number of opioid pills prescribed for pain control after Cesarean section has an effect on patient reported pain levels and satisfaction with pain control during…
- Trial name
- NCT03175653
- Testing
- Oxycodone Pill A, Oxycodone Pill B
- Where
- United States
- Sponsor
- Mount Carmel Health System
Pain, Postoperative
Intravenous Versus Oral Acetaminophen for Postoperative Pain Control After Cesarean Delivery
This study will compare IV (intravenous) versus oral (PO) acetaminophen for postoperative pain after scheduled, elective Cesarean delivery.
- Trial name
- NCT02487303
- Testing
- Acetaminophen Intravenous, Acetaminophen Oral
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Post-Dural Puncture Headache
The Influence of Needle Diameter on Post Dural Puncture Headache
The purpose of this study is to determine whether injection needle pen point type 'PP Gauge 25' should be recommended as a primary choice of needle (in stead of 'PP Gauge 27') for healthy pregnant women who at delivery (vaginal…
- Trial name
- NCT02827058
- Testing
- G25 pencil point needle, G27 pencil point needle
- Where
- 3 sites in Norway
- Volunteers
- 65 people
- Sponsor
- Helse Nord-Trøndelag HF
Anesthesia, Analgesia
The Efficacy and Safety of S-ketamine in Elective Cesarean Section
During the past years, a large number of clinical trials have investigated the use of the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist racemic ketamine as an adjunct to local anaesthetics, opioids, or other…
- Conditions
- Anesthesia, Analgesia, Depression, Cesarean Section
- Trial name
- ES-CS (NCT04657107)
- Testing
- S-ketamine, normal saline
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Beijing Obstetrics and Gynecology Hospital
Labor Onset and Length Abnormalities
Goal-directed Labor Epidural Analgesia Maintenance
The GLEAM trial is a multicenter, pragmatic, cluster-randomized trial to assess the effects of programmed intermittent epidural bolus versus continuous epidural infusion on the rate of spontaneous vaginal delivery and several…
- Trial name
- GLEAM (NCT05255263)
- Testing
- PIEB, CEI
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Transcutaneous Electric Nerve Stimulation, Analgesia
Transcutaneous Electrical Nerve Stimulation for Post-Cesarean Pain Control
Purpose of study is to evaluate the efficacy of transcutaneous electrical nerve stimulation (TENS) for post-operative pain control after a cesarean delivery compared to placebo and no TENS.
- Conditions
- Transcutaneous Electric Nerve Stimulation, Analgesia, Cesarean Section
- Trial name
- NCT04399707
- Testing
- Transcutaneous electrical nerve stimulation (TENS) unit
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hawaii Pacific Health
Postoperative Pain, Cesarean Section Pain
Comparison of Dexmedetomidine + Ketamine for Postoperative Pain in C-Section
This study aims to compare three different doses of dexmedetomidine, when combined with a fixed dose of ketamine, for pain control in women undergoing cesarean section.
- Trial name
- KETODEX-CS (NCT07022821)
- Testing
- Dexmedetomidine, ketamine
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Fatima Memorial Hospital
Cesarean Delivery, Cesarean Section
Suzetrigine for Opioid-Free Recovery After Cesarean Delivery
The goal of this clinical trial is to determine whether suzetrigine increases the proportion of patients who remain completely opioid-free from completion of surgery through 72 hours after cesarean delivery.
- Conditions
- Cesarean Delivery, Cesarean Section, Pain, Postoperative, Opioid Consumption, Postoperative
- Trial name
- SPARE (NCT07534709)
- Testing
- Suzetrigine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Texas at Austin
Postoperative Pain, Acute
Effect of Transcutaneous Vagus Nerve Stimulation for Pain Control After Cesarean Delivery
This study investigates whether non-invasive transcutaneous auricular vagus nerve stimulation can alleviate postoperative pain in patients after cesarean section, and explores its possible mechanisms of action through an…
- Trial name
- NCT06788561
- Testing
- Transauricular Nerve Stimulation, s-taVNS
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Beijing Tongren Hospital
Spinal Anesthesia, Post Operative Analgesia
Dexamethasone in Prolonging the Duration of Spinal Anesthesia Among Pregnant Patients
Lower segment C section is one of the most commonly performed surgeries worldwide. It is performed in spinal anesthesia. During Spinal Anesthesia a local anesthetic drug is administered in a space surrounding spinal cord and it…
- Trial name
- NCT07088146
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Pregnancy
Comparative Study of Ropivacaine and Ropivacaine With Dexmeditomedine in TAP Blocks
Comparative study of Ropivacaine and Ropivacaine with dexmedetomidine in transversus abdominis plane (TAP) block for post-operative analgesia in patients undergoing Caesarean Section.
- Trial name
- NCT02472522
- Testing
- Ropivacaine + Dexmedetomidine, Ropivacaine
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Tata Main Hospital
Pain
Does Intraperitoneal Instillation of Lidocaine at Cesarean Delivery Improve Postoperative Analgesia?
The instillation of local anesthetic into the peritoneum has been found to be safe and effective in reducing postoperative pain and morphine consumption after abdominal surgery.
- Trial name
- NCT02264795
- Testing
- Lidocaine
- Where
- Canada
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Labor Pain
Characteristics of the Tsui Test and Pressure Waveform to Confirm Epidural Catheter Placement in Parturients With BMI ≥50 kg/m2
The prevalence of obesity has increased worldwide, and the anesthetic care of patients with obesity remains a challenge for providers despite advances.
- Trial name
- NCT05361512
- Testing
- Tsui test, epidural waveform analysis
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Postoperative Analgesia, Cesarean Section
Postoperative Analgesia After Cesarean Section; Comparison Among Ultrasound Guided Erector Spinae, Quadratus Lumborum or Transversus Abdominis Plane Blocks
The aim of this prospective randomized controlled study is to compare the analgesic efficacy of the ultrasound-guided erector spinae plane block, ultrasound-guided quadratus lumborum plane block, and ultrasound-guided transversus…
- Conditions
- Postoperative Analgesia, Cesarean Section, Erector Spinae Block, Quadratus Lumborum Block
- Trial name
- NCT06451354
- Testing
- Erector spinae plane block (20 ml bupivacaine 0.25% in each side), Posterior Quadratus lumborum plane block (20 ml bupivacaine 0.25% in each side), Lateral Transversus abdominis plane block (20 ml bupivacaine 0.25% in each side)
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Kafrelsheikh University
Anaesthesia, Spinal
Pain Control and Side Effects in Cesarean Section Anesthesia: Comparison of Intrathecal Morphine and Fentanyl
Intrathecal opioids are frequently combined with local anesthetics to optimize spinal anesthesia for cesarean delivery. Fentanyl, a lipophilic opioid, offers rapid onset and enhanced intraoperative analgesia.
- Trial name
- FvMinSACS (NCT07144410)
- Testing
- fentanyl + morphine, fentanyl
- Where
- Romania
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Oradea
Postoperative Pain After Cesarean Section
TAP vs. ESP Blocks for Post-Cesarean Analgesia
This study compares the effectiveness of two ultrasound-guided nerve blocks (TAP block and ESP block) versus standard pain management for relieving pain after a planned cesarean section.
- Trial name
- RCT-TAP-ESP-CS (NCT07853482)
- Testing
- Ropivacaine, Ultrasound-guided Nerve Block, Ketoprofen and Paracetamol
- Where
- Russia
- Volunteers
- 162 people
- Sponsor
- Maternity Hospital - State Budgetary Institution of the Rostov Region, Taganrog