Clinical trials: Analgesia, Cesarean
Regional Block for Postoperative Analgesia in Cesarean Section
Comparison Between Erector Spinae Plane Block vs Transversus Abdominis Plane Block for Postoperative Analgesia in Cesarean Section
This study is a prospective randomized controlled trial designed to compare the effectiveness of the erector spinae plane (ESP) block versus the transversus abdominis plane (TAP) block for postoperative analgesia in patients…
- Trial name
- NCT07582640
- Testing
- Erector Spinae Plane Block For Postoperative Analgesia In Cesarean Section, Transversus Abdominis Plane Block For Postoperative Analgesia In Cesarean Section
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Pain, Postoperative
Usage of Tramadol With Levobupivacaine for Pain Treatment After Cesarean Section
Patients experience considerable amount of pain after cesarean section. The aim of this study is to investigate the effect of tramadol (an opioid pain killer) added to levobupivacaine (a local anesthetic) in continuous wound…
- Trial name
- NCT01916915
- Testing
- Tramadol infusion via wound catheter, Levobupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Ufuk University
Pain, Postoperative
The OBstetric Lidocaine Patch (OBLido) Trial
This study will be a single-center, single blind, randomized controlled trial. The study will be conducted at UnityPoint-Health Meriter Hospital under investigators from the University of Wisconsin-Madison.
- Trial name
- OBLido (NCT03810235)
- Testing
- Transdermal Lidocaine Patch
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
C-Section, Pain Management
Evaluate the Safety and Efficacy of EXPAREL When Administered Via Infiltration Into the TAP vs. Bupivacaine Alone in Subjects Undergoing Elective C-Sections
Primary objective: The primary objective of this study is to compare total opioid consumption through 72 hours following EXPAREL+bupivacaine HCl infiltration into the transversus abdominis plane (TAP) after spinal anesthesia to…
- Trial name
- C-Section (NCT03176459)
- Testing
- Exparel + Bupivacaine, Bupivacaine
- Where
- 12 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Cesarean Section Wound
Bilevel Erector Spinae Plane Block Versus Transversus Abdominis Plane Block for Analgesia After Cesarean Delivery.
Optimizing analgesia after cesarian delivery is an essential element of enhancing maternal recovery.A multimodal analgesic approach incorporating truncal blocks can provide effective pain relief with minimal side effects for both…
- Trial name
- NCT07137208
- Testing
- ESP block, TAP Block, Bupivacaine injection
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Postoperative Pain
Dexmedetomidine Wound Infiltration in Cesarean Section
The effects of four different wound infiltration protocols in cesarean section will be investigated on parturient' pain intensity, PCA morphine consumption given, side effects and parturient' overall satisfaction.
- Trial name
- NCT03382938
- Testing
- Dexmedetomidine, Ropivacaine, Dexmedetomidine - Ropivacaine
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Attikon Hospital
Obstetric Pain, Obstetric Anesthesia Problems
TAP Block vs LAWI for Analgesia Post-cesarean Section
Adequate pain control after cesarean delivery is a significant concern both for parturients and obstetric anesthesiologists. Transversus Abdominis Plane (TAP) block and local Wound infiltration with anesthetics are alternatives…
- Trial name
- NCT05447455
- Testing
- Transversus Abdominis Plane Block, Local anesthetic wound infiltration
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Analgesia
Effect of Intrathecal Morphine on Urinary Bladder Function and Recovery in Patients Having a Cesarean Delivery
The enhanced recovery anesthesia concept has been widely adopted, including cesarean delivery. Modern obstetrical anesthesia aims to offer an experience to a patient undergoing a cesarean delivery similar to normal vaginal…
- Trial name
- NCT05042817
- Testing
- 100 mcg morphine, 0.9% NaCl, 50 mg prilocaine + 2.5 mcg sufentanil
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- University of Liege
Post Operative Pain, Acute, Post Operative Pain, Chronic
Naldebain for Control of Post-Cesarean Section Pain
Inadequate postoperative pain management can lead to physical and psychological distress in patients as well as impact surgical wound healing and increase the risk of developing postoperative delirium and cardiopulmonary and…
- Conditions
- Post Operative Pain, Acute, Post Operative Pain, Chronic, Cesarean Section
- Trial name
- NCT05187520
- Testing
- Patient-controlled epidural analgesia (PCEA), Naldebain®
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- E-DA Hospital
Scheduled Cesarean Sections, Postoperative Pain Management
Low Pain Prediction in Cesarean Section Patients
The investigators are attempting to see if eliminating the amount of long acting spinal narcotic during cesarean section delivery will demonstrate pain scores with movement when evaluated 24 hours postoperatively as those that…
- Conditions
- Scheduled Cesarean Sections, Postoperative Pain Management, Side Effects
- Trial name
- NCT02143141
- Testing
- duramorph
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Wake Forest University Health Sciences
Postoperative Pain, Cesarean Section
Intrathecal Morphine 75 mcg Versus 100 mcg for Post-Cesarean Analgesia: A Randomized Double-blind Trial
This study evaluates the efficacy and safety of two different doses of intrathecal morphine (75 mcg versus 100 mcg) for postoperative analgesia in patients undergoing elective cesarean delivery under spinal anesthesia.
- Conditions
- Postoperative Pain, Cesarean Section, Obstetric Anesthesia
- Trial name
- ITM-CESAREAN (NCT07516717)
- Testing
- Intrathecal Morphine
- Where
- Venezuela
- Volunteers
- 240 people
- Sponsor
- Hospital Universitario de Caracas
Post Operative Pain, Cesarean Section
The Effect of Intravenous Infusion of Tramadol-ondansetron on Recovery After Caesarean Section.
It will be a prospective observational cohort study. The investigators will compare post-cesarean section recovery in patients receiving intravenous infusion of tramadol-ondansetron versus epidural catheter with infusion of local…
- Conditions
- Post Operative Pain, Cesarean Section, Tramadol, Postoperative Recovery
- Trial name
- TRON (NCT05879536)
- Testing
- Tramadol-ondansetron continuous infusion, Ropivacaine via epidural catheter
- Where
- Spain
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Fe
Analgesia
Efficacy of Trans Abdominis Plane Block for Post Cesarean Delivery Analgesia
Relief from pain is part of the fundamental human right to health. (1) However, available evidence indicates an increasingly detailed understanding of the pathophysiology of pain and general inadequacy of its treatment.
- Trial name
- NCT06556381
- Testing
- TAP block
- Where
- Saudi Arabia
- Volunteers
- 100 people
- Sponsor
- Qassim University
Pain, Cesarean Section
Naproxen Versus Tramadol for Post Cesarean Pain Control
Oral naproxen might be more efficacious for post-cesarean pain-control and have better side-effects profile than oral tramadol.
- Trial name
- NCT01165814
- Testing
- Naproxen Tramadol
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Bnai Zion Medical Center
Cesarean Section, Dexamethasone
Intravenous Dexamethasone Effectiveness in Post Caesarean Section Analgesia
The management of postpartum pain is essential to ensure early rehabilitation for parturients. Intravenous dexamethasone has a potent analgesic action when used in the context of general anesthesia.
- Conditions
- Cesarean Section, Dexamethasone, Postoperative Pain, Spinal Anesthesia
- Trial name
- NCT05535036
- Testing
- Dexamethasone 4mg
- Where
- Tunisia
- Volunteers
- 84 people
- Sponsor
- Mongi Slim Hospital
Analgesia, Acute Pain
Comparison of the Effects of QLB 2 and QLB 3 on Post-operative Analgesia in Cesarean Section Surgery
This study evaluates the post-operative analgesic effects of quadratus lomborum block 2 and 3 (QLB 2, 3) in patients having cesarean section with spinal anesthesia.
- Conditions
- Analgesia, Acute Pain, Chronic Pain
- Trial name
- NCT04364906
- Testing
- Regional anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ondokuz Mayıs University
Obstetric Pain
The Effect of the Transversus Abdominis Plane Block to Postoperative Analgesia for Cesarean Section
The transversus abdominis plane block (TAP block) has effect to postoperative analgesia for cesarean section with spinal anesthesia but it was limited for cesarean section with general anesthesia.
- Trial name
- TAP (NCT03634111)
- Testing
- TAP block, Morphine, Ropivacaine
- Where
- Vietnam
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gia Dinh People Hospital
Cesarean Delivery, Esketamine
Different Doses of Dexmedetomidine Combined With Esketamine in Women Undergoing Cesarean Delivery
Esketamine is a commonly used analgesic during cesarean delivery, but may produce transient neuropsychiatric symptoms. Dexmedetomidine has both sedative and analgesic effects.
- Conditions
- Cesarean Delivery, Esketamine, Neuropsychiatric Symptoms, Dexmedetomidine
- Trial name
- NCT06613243
- Testing
- Esketamine 0.2 mg/kg, Esketamine 0.2 mg/kg + dexmedetomidine 0.1 µg/kg, Esketamine 0.2 mg/kg + dexmedetomidine 0.15 µg/kg
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University First Hospital
Cesarean Section, Postoperative Analgesia
Anterior Quadratus Lumborum Block Versus Erector Spinae Plane Block After Elective Cesarean Section
Cesarean section is the one of the most common surgical procedures. Inadequate pain management is associated with increased morbidity, costs, and maternal dissatisfaction.
- Trial name
- NCT05254093
- Testing
- Quadratus lumborum block, erector spinae plane block
- Where
- Egypt
- Volunteers
- 153 people
- Sponsor
- Kasr El Aini Hospital
Cesarean Section, Postoperative Pain
Ketamine for Analgesia After Cesarean Section
In this prospective randomized trial, investigators compared the analgesic effect of subanesthetic dose of ketamine versus placebo in parturients undergoing cesarean section under spinal anesthesia.
- Trial name
- NCT04545801
- Testing
- 0.25 mg/kg of Ketamine, 20ml of normal saline solution
- Where
- Tunisia
- Volunteers
- 80 people
- Sponsor
- Mongi Slim Hospital