Clinical trials: Analgesia, Epidural
Epidural Anesthesia in Labor and Delivery, Doppler Ultrasound
EPidural's Impact on Contractions and Fetal REsponse
This prospective observational study aims to assess the impact of epidural analgesia (ELA) on uterine contractility, cardiotocography (CTG) patterns, and maternal-fetal hemodynamics in term pregnancies.
- Conditions
- Epidural Anesthesia in Labor and Delivery, Doppler Ultrasound, Uterine Contraction
- Trial name
- EPI-CARE (NCT06860854)
- Testing
- Epidural Analgesia
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland
Pain
Sole Local Anesthetic Versus Opioid Plus Local Anesthesia in Epidural Labor Analgesia
It is common for obstetric anesthesia using opioid supplement to local anesthetics for epidural labor pain control. Given the low doses of these epidural drugs, we never doubt the necessity of the supplement of opioid to lacal…
- Trial name
- OLAA (NCT02036242)
- Testing
- Sole local anesthetic, Sufentanil (Opioid plus local anesthetic), Ropivacaine
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Nanjing Medical University
Percutaneous Nephrolithotomy
Lower Thoracic Epidural vs Erector Spinae Block for PNL
compare the efficacy of Lower Thoracic Epidural with Erector spinae plane block (ESPB) for post-operative analgesia after Percutaneous Nephrolithotomy with a hypothesis that both Lower Thoracic Epidural and Erector spinae plane…
- Trial name
- NCT05725083
- Testing
- Lower thoracic epidural, Erector spinae plane block
- Volunteers
- 42 people
- Sponsor
- Assiut University
Pain, Postoperative, Major Abdominal Surgery
Bilateral Transversus Abdominis Plane Block With Exparel Verus Continuous Epidural Analgesia With Bupivacaine
Comparison of Bilateral Transversus Abdominis Plane Block with Exparel versus Continuous Epidural Analgesia With Bupivacaine
- Trial name
- NCT02996227
- Testing
- TAP block, Epidural analgesia, EXPAREL
- Where
- 2 sites in United States
- Volunteers
- 514 people
- Sponsor
- The Cleveland Clinic
Pain Following Thoracotomy Surgery
Study of Exparel Versus Epidural for Pain Control After Thoracotomy
Unilateral intercostal nerve blocks provide pain control as effectively as a continuous thoracic epidural, and will a lower incidence of side effects.
- Trial name
- NCT02178553
- Testing
- Epidural, Intercostal Bupivicaine (Exparel)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Mayo Clinic
Postoperative Pain
NSAIDs With Morphine-PCA Compared to Epidural Analgesia in Thoracotomy Pain
The investigators investigated whether a strictly controlled pain management with patients participating in a clinical study can attenuate persistence of post-thoracotomy pain.
- Trial name
- NCT01541137
- Testing
- Diclofenac, parecoxib/ valdecoxib, patient controlled epidural analgesia
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Helsinki University Central Hospital
Osteoarthritis
Analgesia After Total Hip Arthroplasty: Peri-Articular Injection Versus Epidural Patient Controlled Analgesia (PCA)
The best way to provide analgesia after total hip arthroplasty is hotly debated. There are two protocols in use at Hospital for Special Surgery(HSS).
- Trial name
- PAI Hip (NCT01658072)
- Testing
- Peri-Articular Injection, Epidural Patient Controlled Analgesia (Epidural PCA)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Hospital for Special Surgery, New York
3 or More Rib Fractures
Optimal Method of Pain Management in Patients With Multiple Rib Fractures
Rib fractures are a common injury of trauma patients and can cause significant pain which, if inadequately treated, can lead to impaired breathing, lung collapse, and respiratory failure.
- Trial name
- NCT01401712
- Testing
- ON-Q® Pain Relief System, Thoracic epidural catheter
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Massachusetts General Hospital
Lung Neoplasms, Pain
Supplementary Epidural Analgesia in Video-Assisted Thoracic Surgery (VATS) - The SEAVATS Study
Whereas it, in the case of conventional thoracotomy, has been demonstrated that thoracic epidural analgesia is more effective than systemic opioids in terms of pain relief and preservation of postoperative pulmonary function, the…
- Conditions
- Lung Neoplasms, Pain, Immune Suppression
- Trial name
- SEAVATS (NCT02359175)
- Testing
- Bupivacaine in epidural catheter, Fentanyl in epidural catheter, Oral Paracetamol
- Where
- Denmark
- Volunteers
- 161 people
- Sponsor
- Odense University Hospital
Labour Analgesia
Effect of Epidural Needle Injection on Catheter Placement Success During Painless Labour
Epidural analgesia is the gold standard for painless labour, but successful catheter placement can be technically challenging due to anatomical and physiological changes in pregnancy.
- Trial name
- NCT07327918
- Testing
- Injection Group, Control group
- Where
- Egypt
- Volunteers
- 216 people
- Sponsor
- Al-Azhar University
Prostatectomy, Transversus Abdominis Plane Blockade
Ultrasound-assisted Bilateral Transversus Abdominis Plane Block for Open Prostatectomy
The purpose of this study is to compare the quality of a transversus abdominis plane blockade with an intravenous pain therapy with opioids.
- Conditions
- Prostatectomy, Transversus Abdominis Plane Blockade, Pain
- Trial name
- TAPPro (NCT01625572)
- Testing
- Transversus abdominis plane blockade, Morphine-patient-controlled-analgesia-device
- Where
- Germany
- Volunteers
- 66 people
- Sponsor
- Charite University, Berlin, Germany
Labor, Analgesia, Epidural
Effect of Timing on Efficacy of Morphine Analgesia After 2-chloroprocaine Anesthesia
Epidural chloroprocaine is often used in obstetrical anesthesia because of its fast onset and short duration. These properties make it an ideal drug to use for epidural anesthesia in patients undergoing postpartum tubal ligation.
- Trial name
- NCT00487084
- Testing
- Morphine-CP-saline (MCS), saline-2CP-morphine (SCM), saline-lidocaine-morphine (SLM)
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Labor Pain
Does Ultrasound Scanning of the Lumbar Spine Improve Patient Satisfaction and the Ease of Insertion Epidurals?
Ultrasound scanning of the back has been shown to increase success when used to guide epidural catheter insertion. However, this technique is not applied widely in clinical practice.
- Trial name
- NCT00996905
- Testing
- Portable ultrasound machine
- Where
- Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pain Relief
Comparison of Loss of Resistance Techniques
The purpose of this study is to determine whether there is a difference in success outcome of the combined spinal epidural labor analgesia between air versus saline when used to identify the epidural space.
- Trial name
- NCT00638274
- Testing
- Air, Saline
- Where
- United States
- Volunteers
- 356 people
- Sponsor
- Wake Forest University Health Sciences
Upper Gastrointestinal Surgery, Post-operative Analgesia
Comparison of Continuous Wound Catheter Infusion Versus Continuous Epidural Infusion in Abdominal Surgery
Comparison of efficacy in management of pain in abdominal surgery between epidural versus wound infusion catheter {catheter placed within the incision site}
- Conditions
- Upper Gastrointestinal Surgery, Post-operative Analgesia, Wound Infusion Catheter, Upper Midline Incision
- Trial name
- NCT02782767
- Testing
- Wound catheter infusion, Epidural infusion
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Labor Pain
Comparison of Dural Puncture Epidural Versus Conventional Epidural for Labour Analgesia in Primigravida
This study aims to compare the analgesic efficacy and safety of the Dural Puncture Epidural (DPE) technique versus the Conventional Epidural (CE) technique for labor analgesia in primigravida.
- Trial name
- NCT06766812
- Testing
- epidural set
- Volunteers
- 60 people
- Sponsor
- Sohag University
Epidural; Analgesia
Continuous Versus Intermittent Administration of Epidural Analgesia During Labor
prospective randomized single blind study, including full term adult parturients, ASA 2, 3 status, scheduled for vaginal delivery. patients were randomized at 3 cm of cervix dilatation, into 2 groups.
- Trial name
- NCT04826120
- Testing
- PCEA Infusion, Continuous epidural infusion
- Where
- 2 sites in Tunisia
- Volunteers
- 54 people
- Sponsor
- Mongi Slim Hospital
Lumbar Spine Fixation
Fentanyl as Adjuvants to Epidural Bupivacaine Plus Dexamethasone for Analgesia
The purpose of this study is to compare better postoperative analgesia after lumbar spine Fixation using either epidural bupivacaine with midazolam or fentanyl with the combination of dexamethasone.
- Trial name
- NCT06898697
- Testing
- postoperative analgesia, epidural fentanyl
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
Post Operative Pain, Acute, Post Operative Pain, Chronic
Naldebain for Control of Post-Cesarean Section Pain
Inadequate postoperative pain management can lead to physical and psychological distress in patients as well as impact surgical wound healing and increase the risk of developing postoperative delirium and cardiopulmonary and…
- Conditions
- Post Operative Pain, Acute, Post Operative Pain, Chronic, Cesarean Section
- Trial name
- NCT05187520
- Testing
- Patient-controlled epidural analgesia (PCEA), Naldebain®
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- E-DA Hospital
Epidural Analgesia
Efficacy and Safety of Electrical Stimulation-guided Epidural Analgesia for Vaginal Delivery
Forty pregnant women (36 to 41 weeks gestation) will randomly allocate to two groups. Groups will be defined based on the method used to identify the epidural space for epidural anesthesia: the loss of resistance group (n=20) and…
- Trial name
- NCT03161717
- Testing
- Epidural electrical stimulation (EES), Loss of resistance (LOR)
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sang Sik Choi