Clinical trials: Analgesia, Postoperative
Quality of Recovery, Pain, Postoperative
Quality of Recovery After Laparoscopic Cholecystectomy Comparing Opioid Free Analgesia Versus Opioid Free Anesthesia
The aim of this study is to compare the quality of recovery from general anesthesia and surgery using the quality of recovery 15 item scale (QoR-15) for participant's receiving opioid-Sparing anesthesia with those receiving…
- Conditions
- Quality of Recovery, Pain, Postoperative, Elective Laparoscopic Cholecystectomy
- Trial name
- NCT06343753
- Testing
- Opioid free analgesia, Opioid based Anesthesia
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Laparoscopic Cholecystectomy
Comparison Between Dexmedetomidine and Fentanyl As an Adjuvant to Bupivacaine in the Paravertebral Nerve Block in Laparoscopic Cholecystectomy for Postoperative Analgesia: Randomized Comparative Clinical Trial.
Laparoscopic cholecystectomy is one of the most common surgeries today, cause it has many advantages over open cholecystectomy. Although these advantages pain remains a big problem after laparoscopic cholecystectomy which causes…
- Trial name
- NCT06752629
- Testing
- Bupivacaine and Dexmedetomidine, Bupivacaine and Fentanyl
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Post Cesarean Analgesia
Comparison Between Ketamine Intrathecal and iv Dexamethasone for Post Cesarean Analgesia
The aim of our study is to compare the postoperative analgesic efficacy of intrathecal ketamine added to bupivacaine to that of intravenous dexamethasone in patients undergoing cesarean section under bupivacaine spinal anesthesia.
- Trial name
- NCT06408974
- Testing
- Ketamine, dexamethasone
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pain, Postoperative
Effectiveness of Port Site Bupivacaine Injection in Postoperative Pain Reduction After Lap. Chole
To determine the effectiveness of port site bupivacaine infiltration in postoperative pain reduction after laparoscopic cholecystectomy.
- Trial name
- NCT05264805
- Testing
- 0.25% Bupivacaine
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Hamdard University
Acute Postoperative Pain, Chronic Postoperative Pain
Femoral and Epidural Block After Total Knee Arthroplasty
Total knee prosthetic replacement causes severe postoperative pain. Various analgesic techniques have been used in pain control.
- Trial name
- NCT02115945
- Testing
- DN4 test, The SF 12 test, HAD scale
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Post Operative Pain
Cold Therapy for Pain Control Following Caesarean Section
Cold Therapy has been used for a variety of procedures and has been studied in several but not recently studied for reducing postop pain following Caesarean Sections.
- Trial name
- NCT03711994
- Testing
- Alkantis
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Pain, Postoperative
Bupivacaine Hydrochloride for Pain Control in Cutaneous Surgery
The purpose of this study is to determine if the addition of bupivacaine HCl injections will improve pain control after skin surgery. This is a randomized clinical trial.
- Trial name
- NCT04260854
- Testing
- Bupivacaine Hydrochloride, Saline
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pain, Postoperative, Analgesia
Pre-operative Analgesics for Postoperative Pain Relief After Dental Treatment
The aim of the study is to compare the efficacy of the pre-operative administration of Paracetamol and placebo in reducing postoperative pain after routine dental treatment in children.
- Trial name
- NCT02393339
- Testing
- paracetamol
- Where
- Israel
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Postoperative Pain Atskin Graft Site
Comparison of Bupivacaine Versus Bupivacaine-dexamethasone Infiltration for Postoperative Analgesia in Skin Graft Donor Sites
Background: Skin grafting; both partial and complete thickness is frequently used in reconstruction of traumatic soft tissue defects.
- Trial name
- NCT03967392
- Testing
- Xylocaine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Pain, Mandible Fracture
Postoperative Pain After Bupivacaine Supplementation in Mandibular Fracture Surgery
Pain following open reduction of mandibular fractures is the most reported complaint during the first 24 post-operative hours. The goal of this clinical trial is to evaluate the impact of inferior alveolar nerve block with…
- Conditions
- Postoperative Pain, Mandible Fracture, Analgesia, Anesthesia, Local
- Trial name
- NCT06243263
- Testing
- Bupivacain
- Where
- 2 sites in Tunisia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Laparoscopic Cholecystectomy
ERAS (Enhanced Recovery After Surgery) and Multimodal Analgesia in Laparoscopic Cholecystectomy
This clinical study aims to evaluate the effects of multimodal analgesia management administered within an ERAS (Enhanced Recovery After Surgery) protocol on postoperative pain, length of hospital stay, early complications, and…
- Trial name
- ERAS (NCT06885086)
- Testing
- Control group - 1, Observation group -2
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Postoperative Pain
Effect of Posterior Femoral Cutaneous Nerve Block on Postoperative Posterior Lateral Knee Analgesia in Patients With TKA
The aim of this study was to observe the effects of posterior femoral cutaneous nerve block combined with sciatic and saphenous nerve block compared with sciatic and saphenous nerve block alone on postoperative posterior side of…
- Trial name
- NCT06522620
- Testing
- Posterior Femoral Cutaneous Nerve Combined With Proximal Sciatic and Saphenous Nerve Block, Simple Sciatic and Saphenous Nerve Blocks
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Quadratus Lumborum Block
Transmuscular Quadratus Lumborum Block on Post-Operative Analgesia After Total Hip Arthroplasty
The aim of this study is to compare between the post-operative analgesic effect of two approaches of transmuscular quadratus lumborum block (transverse versus paraspinous sagittal transmuscular QLB) in total hip replacement…
- Trial name
- NCT05465967
- Testing
- Quadratus lumborum Block
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tanta University
Pain
Could Algometric Assessment be Effective to Adjust Postoperative Analgesic Requirement?
The purpose of this study is to determine the correlation between preoperative algometer score and the amount of postoperative analgesic consumption.
- Trial name
- NCT02375607
- Testing
- Algometer
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Complications; Cesarean Section
Preoperative Cesarean Section Intravenous Acetaminophen and Postoperative Pain Control
To evaluate the use of maternal opiates for pain control post cesarean delivery in those patients that received intravenous acetaminophen 1000 mg in 150 mL of normal saline, infused 30 minutes prior to incision compared to…
- Trial name
- NCT02694653
- Testing
- Acetaminophen
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Tennessee Graduate School of Medicine
Pain, Acute
Phase III Efficacy and Tolerability Trial of the Fixed Dose Combination of Etodolac 400 mg and Cyclobenzaprine 10 mg Versus Isolated Active Substances in Pain Control After Impacted Third Molar Extraction
This Phase III study will compare the efficacy and tolerability of a Fixed Dose Combination of Etodolac + Cyclobenzaprine versus the isolated drugs in postoperative pain control after impacted third molar extraction.
- Trial name
- FDCETCB-III (NCT03127592)
- Testing
- Fixed Dose Combination, Etodolac, Cyclobenzaprine
- Where
- Brazil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Apsen Farmaceutica S.A.
Low Level Laser Therapy, Healthy
Effect of GaAlAs 940 Laser on Pain and Wound Healing After Free Gingival Graft
This randomized controlled clinical trial aims to evaluate the biomodulatory effects of a 940-nm GaAlAs diode laser on postoperative pain control and wound healing at the palatal donor site following free gingival graft…
- Conditions
- Low Level Laser Therapy, Healthy, Postoperative Pain Management, Wound Healing
- Trial name
- NCT07308912
- Testing
- 940 nm GaAlAs diode laser, palatal stent
- Where
- Vietnam
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Wound Healing and Prevention, Oral Inflammation
Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva
The intervention in this study is to determine whether multiple applications of photobiostimulation with Nd-YAG laser improve wound healing following tooth extraction and alveolar ridge preservation.
- Conditions
- Wound Healing and Prevention, Oral Inflammation, Photobiomodulation, Post-operative Pain Management
- Trial name
- NCT07095556
- Testing
- Low-level laser therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Analgesia
Ultrasound Guided Block for Postoperative Analgesia in Arthroscopic Shoulder Surgery
This study aimed to compare the efficacy of high thoracic-ESPB with shoulder block as analgesic options for arthroscopic shoulder surgery. Primary outcome: 24-hour analgesic consumption.
- Trial name
- NCT06202430
- Testing
- High Thoracic Erector Spinae Plane Block, Shoulder Block
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Emergence Agitation, Pain
Emergence Agitation and Pain Scores in Pediatrics When Comparing Single-modal vs Multi-modal Analgesia for ENT Surgery
The purpose of this study is to compare the incidence of EA in pediatric patients undergoing minor ENT surgery under Sevoflurane and compare opioid-only based intra-operative analgesia to multi-modal analgesia consisting of…
- Trial name
- NCT03062488
- Testing
- IV acetaminophen, Fentanyl, PO acetaminophen
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic