Clinical trials: Analgesia, Postoperative
Internal Derangement of Knee
Infrapatellar Nerve Block for Post-operative Knee Arthroscopy Pain Control
The purpose of this study is to determine whether infrapatellar branch of the saphenous nerve blocks are effective in decreasing analgesic use, promoting earlier mobility, and improving long term outcome scores after knee…
- Trial name
- NCT01279447
- Testing
- 0.25% Bupivacaine, Normal Saline
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Gynecological Disease
The Effectiveness of a Virtual Reality-based Multisensory Intervention
This study explores the effectiveness of a virtual reality-based multisensory intervention for postoperative recovery in patients receiving gynecological surgery.
- Trial name
- NCT06922838
- Testing
- Virtual Reality intervention, Aromatherapy
- Volunteers
- 100 people
- Sponsor
- Weifang Medical University
Laparoscopic Cholecystectomy
Intraperitoneal Ropivacaine Nebulization for Pain Control After Laparoscopic Surgery
The purpose of this study is to assess if intraperitoneal nebulization of Ropivacaine 50 mg, 100 mg or 150 mg may prevent the use of morphine during the first day after laparoscopic cholecystectomy.
- Trial name
- NCT01143025
- Testing
- Ropivacaine 50 mg, Ropivacaine 100 mg, Ropivacaine 150 mg
- Where
- Italy
- Volunteers
- 165 people
- Sponsor
- San Gerardo Hospital
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluating The Use of CGF Made Gel in Mandibular Extraction Sites of Lower Impacted 3rd Molars.
The goal of this clinical trial is to learn if Concentrated Growth Factor (CGF) Gel help improve bone healing and reduce pain after the surgical removal of impacted lower third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07520097)
- Testing
- Concentrated Growth Factor (CGF) Gel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Analgesia
Analgesia After Knee Arthroscopy :Dexmedetomidine vs Fentanyl
The aim of this study is to evaluate analgesic effects Bupivacaine, Bupivacaine plus Dexmedetomidine and Bupivacaine plus Fentanyl in relieving pain after knee arthroscopic surgery.
- Trial name
- NCT04442906
- Testing
- Dexmedetomidine, Fentanyl, Bupivacain
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Preoperative, Sleep Disturbance
Preoperative Oral Midazolam to Postoperative Pain Relief in Sleep Disturbance or Anxiety Patients With Colorectal Cancer
Previous studies have indicated a high incidence of sleep disturbances and anxiety symptoms in individuals with colorectal cancers prior to undergoing surgery, leading to worsened postoperative pain, slower recovery, and higher…
- Conditions
- Preoperative, Sleep Disturbance, Anxiety, Midazolam
- Trial name
- POMPPR (NCT06407518)
- Testing
- Midazolam oral solution
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Postoperative Pain, Shoulder Arthroscopy
Interscalene Brachial Plexus Block Versus Serratus Posterior Superior Intercostal Plane Block for Arthroscopic Shoulder Surgery
Arthroscopic shoulder surgery is associated with moderate to severe postoperative pain that may delay recovery and rehabilitation.
- Trial name
- SISA (NCT07668648)
- Testing
- Interscalene Brachial Plexus Block, Serratus Posterior Superior Intercostal Plane Block, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ferit Yetik
Postoperative Analgesia
Quadratus Lumborum Block Versus Thoracic Paravertebral Block
This study is to assess and compare the analgesic efficacy and safety of quadratus lumbotum block and paravertebral block in gynacological cancer patients.
- Trial name
- NCT04827043
- Testing
- Ultrasound guided quadratus lumborum block, Ultrasound guided thoracic paravertebral block
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute, Egypt
Pain, Postoperative
Survey of Postoperative Pain and Pain Management in Norwegian Hospitals
The study is a national survey of pain and pain management to surgical patients in Norwegian Hospitals. Data on pain management are gathered from patient records and data on pain and patient satisfaction are gathered as patients'…
- Trial name
- NCT01413724
- Volunteers
- 300 people
- Sponsor
- Norwegian University of Science and Technology
Pain, Postoperative
The Efficacy and Safety of NALDEBAIN for the Treatment of Post-Laparotomy Surgery
The primary objective of this study is to determine the safety and efficacy of single doses of intramuscular NALDEBAIN on patients scheduled to undergo elective laparotomy.
- Trial name
- NCT03296488
- Testing
- Nalbuphine Sebacate, Fentanyl Citrate
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Pain
A Study to Evaluate the Efficacy and Safety of HRS4800 Tablets for Postoperative Analgesia After Impacted Teeth Removal Surgery.
The study is being conducted to evaluate the efficacy and safety of HRS4800 tablets for postoperative analgesia after impacted teeth removal surgery.
- Trial name
- NCT05318846
- Testing
- HRS4800 tablets
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Intercostal Nerve Block, Cryo Analgesia
Cryo Nerve Block Trial
Background: Minimally invasive lung surgery, such as video-assisted thoracoscopic surgery (VATS) or robot-assisted thoracoscopic surgery (RATS), has become more common for lung resections because it leads to faster recovery, less…
- Conditions
- Intercostal Nerve Block, Cryo Analgesia, Minimally Invasive Lung Surgery
- Trial name
- NCT06861387
- Testing
- Cryotherapy, PAiN - multimodal analgesia
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- St. Antonius Hospital
Ankle (Ligaments); Instability (Old Injury), Ankle Sprain
A Study on Reducing Opioid Use After Ankle Arthroscopy
Study Title Effect of a Postoperative Multimodal Analgesic Protocol Predominantly Based on Non-Opioid Medications vs Opioid-Based Analgesia on Pain After Ankle Arthroscopy: A Noninferiority Randomized Clinical Trial Purpose This…
- Conditions
- Ankle (Ligaments); Instability (Old Injury), Ankle Sprain, Talus Osteochondral Defect, Opioid Analgesia
- Trial name
- NCT07154433
- Testing
- Opioid Analgesic Regimen, Non-opioid analgesic regimen
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Spinal Surgery, Pain Intensity
Dexmedetomidine-esketamine Combination and Moderate-to-severe Pain After Spinal Surgery
Spinal surgery is generally followed by severe postoperative pain, and poor pain control may cause adverse outcomes such as cardiovascular events, neurocognitive disorders, and chronic postsurgical pain (CPSP).
- Conditions
- Spinal Surgery, Pain Intensity, Dexmedetomidine, Esketamine
- Trial name
- NCT07523321
- Testing
- Combined dexmedetomidine-esketamine administration
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Peking University First Hospital
Postoperative Pain
Auricular Acupuncture vs. Sham Procedure for Pain Control After Knee Arthroplasty
Aim of the study To investigate whether auricular acupuncture (AA) will reduce postoperative pain and analgesic requirement in comparison with sham AA in patients after elective knee arthroplasty Design Prospective randomized…
- Trial name
- AA_K-TEP (NCT03114449)
- Testing
- Auricular acupuncture
- Volunteers
- 150 people
- Sponsor
- University Medicine Greifswald
Post Operative Pain
Ultrasound Guided Erector Spinae Plane Block Versus Quadratus Lumborum Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Sleeve Gastrectomy
Postoperative pain control is a significant challenge in medical practice. Inadequate pain control could decrease patient's satisfaction, delay postoperative ambulation, increase the incidence of pulmonary and cardiac…
- Trial name
- NCT05141955
- Testing
- Group Erector Spinae Plane Block (ESPB), Group Quadratus Lumborum Block (QLB), Group (C) (Control group)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Pain, Hispanics
Efficacy of NSAID and Acetaminophen in the Control of Post-Operative Pain in Patients Undergoing Total Knee Replacement
An alternate perioperative pain control protocol composed of intravenous ketorolac and oral acetaminophen for patients who underwent total knee replacement was designed with the aim to determine its efficacy when compared to pain…
- Conditions
- Pain, Hispanics, Opioid Use, Multimodal Analgesia
- Trial name
- NCT05393414
- Testing
- Opioid based protocol, Opioid sparing protocol
- Where
- Puerto Rico
- Volunteers
- 81 people
- Sponsor
- University of Puerto Rico
Postoperative Pain, Liver Resection
Novel Technique of Analgesia Following Open Liver Resection
Abdominal wall incisions used for liver surgeries are associated with significant postoperative pain and disability. Epidural analgesia is often contraindicated in these patients due to common bleeding problems.
- Trial name
- NCT01960049
- Testing
- ropivacaine + iv PCA, saline and IV PCA
- Where
- 2 sites in Canada
- Volunteers
- 150 people
- Sponsor
- University Health Network, Toronto
Post Operative Pain, Spinal Fusion
Postoperative Pain Control in AIS Using Liposomal Bupivacaine vs. 0.25% Bupivacaine With Epinephrine
A randomized controlled trial (RCT) investigating whether the local anesthetic injection of liposomal bupivacaine during posterior spinal fusion (PSF) for AIS is more effective in reducing acute postoperative opioid consumption…
- Trial name
- NCT06471348
- Testing
- Bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride and Epinephrine Injection
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Boston Children's Hospital
Pain, Postoperative
Preemptive Analgesia With Amitryptyline for Prevention of Pain in Women After Hysterectomy
The purpose of this study is to determine whether amitryptyline is effective in the prevention of pain in women after a total abdominal hysterectomy.
- Trial name
- NCT03587025
- Testing
- Amitriptyline
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- University of Campinas, Brazil
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