Clinical trials: Analgesia, Postoperative
Nerve Block
Nerve Blocks With Dexamethasone and Local Anaesthetic to Improve Postoperative Analgesia
Can the association of dexamethasone to the local anaesthetic in a single-shot femoral and sciatic nerve block improve analgesia postoperatively in patients submitted to total knee arthroplasty? Primary aim: Evaluate the efficacy…
- Trial name
- NCT02436694
- Testing
- Local Anesthetic ropivacaíne, Perineural Dexamethasone
- Where
- Portugal
- Volunteers
- 56 people
- Sponsor
- Centro Hospitalar do Porto
Pain, Postoperative, Nerve Block
Paravertebral Blocks for Breast Cancer Surgery
This research project intends to look at the effect that a certain type of freezing injection, called a paravertebral block, has on the pain after an operation for breast cancer, the amount of pain relief that is needed and the…
- Trial name
- NCT01904266
- Testing
- GA + paravertebral block
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Alberta
Knee Disease, Nerve Pain
Triple Injection Peri-sartorius (TIPS) Block
Comparison between the pain scores after total knee arthroplasty in patients receiving triple injection peri-sartorius (TIPS) block versus femoral nerve block (FNB)
- Trial name
- NCT05289427
- Testing
- ultrasound guided triple injection peri-sartorius block, Femoral Nerve Block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Elective Laproscopic Bilateral Inguinal Hernia, Elective Laproscopic Cholecystectomy
Controlled Release of Oxycodone 10 mg In Pre-Medication For The Post Operative Analgesia In Elective Laparoscopic Bilateral Inguinal Hernia And Elective Laparoscopic Cholecystectomy
A Prospective Double Blind RCT: Controlled Release Oxycodone 10 mg On a 12 h Dosing Schedule Started With The Premedication ,Placebo Controlled Study,On Post Operative Analgesia Management in Laparoscopic Cholecystectomy and…
- Trial name
- NCT00480142
- Testing
- Oxycodone 10 mg
- Volunteers
- 100 people
- Sponsor
- Kaplan Medical Center
Postoperative Complications, Postoperative Pain
Suprainguinal Fascia Iliaca Block Versus PENG Block for Hip Arthroplasty Analgesia
In recent years, suprainguinal fascia iliaca block (SFIB) has emerged as a reliable analgesic option for primary total hip arthroplasty (THA).
- Conditions
- Postoperative Complications, Postoperative Pain, Weakness, Muscle, Motor Activity
- Trial name
- NCT04402450
- Testing
- Ultrasound-guided suprainguinal fascia iliaca nerve block, Ultrasound-guided pericapsular nerves group of the hip block
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- University of Chile
Pain, Postoperative
Video-assisted Thoracoscopic Surgery - Exparel Study
Video-assisted thoracoscopic surgery (VATS) greatly decreased the number and types of surgery that required open thoracotomy. Initially it was thought that VATS would lead to a reduction of respiratory problems and less acute…
- Trial name
- NCT04864210
- Testing
- Liposomal bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Nada Sadek
Total Hip Arthroplasty (THA), Postoperative Pain Management After Total Hip Arthroplasty
MRI-Based Assessment of Local Anesthetic Spread in the PENG Block Compartment
This study uses MRI imaging to evaluate the spread of local anesthetic following the administration of a pericapsular nerve group (PENG) block.
- Trial name
- MRI-PENG (NCT07040423)
- Testing
- PENG Block, Magnetic resonance imaging
- Where
- Italy
- Volunteers
- 6 people
- Sponsor
- Campus Bio-Medico University
Cardiac Surgery Patient, Postoperative Pain
Effect of Intraoperative Morphine on Postoperative Pain After CABG
Ethics committee approval was obtained for this study, which was planned as a prospective, randomized, controlled, single-center trial to be conducted in patients undergoing coronary artery bypass grafting (CABG) surgery between…
- Conditions
- Cardiac Surgery Patient, Postoperative Pain, Pain After Surgery
- Trial name
- NCT07472959
- Testing
- In this study, morphine administration, which is routinely and frequently used in our operating room for patients undergoing CABG, was applied as an additional intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain
Bupivacaine Pain Pumps to Decrease Mastectomy Post-Operative Pain
This double-blind, randomized, controlled clinical trial comparing patient-reported pain and pain medication/narcotic use between patients randomized to treatment (bupivacaine) or placebo (saline) delivered via pain pump to the…
- Trial name
- NCT01494259
- Testing
- Bupivacaine, Saline
- Where
- United States
- Sponsor
- Johns Hopkins University
Postoperative Pain, Anesthesia, Regional
Mid-Transverse Process to Pleural (MTP) Block and Erector Spinal Plan (ESP) Block in Spinal Surgery
Ethics committee approval was taken on October 22, 2019, numbered 19/342. 120 adult patients who will undergo spine stabilization surgery between October 2019 and January 2020 in "Gülhane Training and Research Hospital" were…
- Conditions
- Postoperative Pain, Anesthesia, Regional, Spinal Stenosis
- Trial name
- NCT04193488
- Testing
- MTP block, ESP block, No Block group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Nephrolithotomy, Percutaneous, Anesthetics, Local
Efficiency of Erector Spinae Plane Block For Patients Undergoing Percutaneous Nephrolithotomy
Investigators' goal is to determine whether Erector Spinae Plane Block would provide a better analgesia, help mobilization and early discharge or increase satisfaction for patients undergoing Percutaneous Nephrolithotomy(PNL).
- Conditions
- Nephrolithotomy, Percutaneous, Anesthetics, Local, Nerve Block, Erector Spinae Plane Block
- Trial name
- NCT03652103
- Testing
- Ultrasound Guided Erector Spinae Plane Block Catheterisation, Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Bozyaka Training and Research Hospital
Laparoscopic Cholecystectomy
Effect of Preemptive Ibuprofen and Dexketoprofen in Patients Undergoing Laparoscopic Cholecystectomy
The primary aim of this study is to investigate the effects of preventive ibuprofen and dexketoprofen on postoperative opioid requirement in patients undergoing elective laparoscopic cholecystectomy.
- Trial name
- NCT03607266
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Yuzuncu Yil University
Postoperative Retention of Urine, Postoperative Urinary Tract Infection
Day Zero Urinary Catheter Removal in Gen Thoracic Surgery Patients
Current standard of practice in study institution dictates day of surgery urinary catheter removal in general thoracic surgery patients receiving thoracic epidural analgesia.
- Trial name
- NCT01309529
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Memorial Health System
Post Operative Pain, Total Knee Replacement
Comparative Pain Control Between 0.2 or 0.3 Spinal Morphine and 0.25 or 0.5 % Bupivacaine for FNB After TKA
Comparative efficacy of 24 and 48 hours post operative pain control in single total knee replacement between intrathecal bupivacaine with 0.2 or 0.3 mg morphine together with 0.25 or 0.5 % bupivacaine for single femoral nerve…
- Trial name
- NCT00795223
- Testing
- morphine and bupivacaine, spinal morphine and marcaine
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- Mahidol University
Postoperative Pain, Postoperative Nausea
Autonomic Neural Field Block for Visceral Pain in Minimally Invasive Left-Sided Colectomy
Effective postoperative pain control is a core component of enhanced recovery after surgery (ERAS) pathways in colorectal surgery; however, postoperative pain following minimally invasive left-sided colectomy remains a persistent…
- Conditions
- Postoperative Pain, Postoperative Nausea, Opioid Use
- Trial name
- ANfiELD (NCT07351994)
- Testing
- Autonomic Neural Field Block
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Antonio Caycedo, MD
Quadratus Lumborum Block, Analgesia
Transversus Abdominis Plane Block Plus Quadratus Lumborum Block or Retrolaminar Block of Multiple Injections for Postoperative Analgesia Following Laparoscopic Colorectal Surgery
Our hypothesis was that transversus abdominis plane block plus retrolaminar block would reduce postoperative sufentanil consumption and provide superior analgesia compared with transversus abdominis plane block plus quadratus…
- Conditions
- Quadratus Lumborum Block, Analgesia, Laparoscopic, Colorectal
- Trial name
- NCT05416866
- Testing
- Retrolaminar block on the operative side, Quadratus lumborum block on the operative side, Transversus abdominis plane block on the nonoperative side
- Volunteers
- 100 people
- Sponsor
- dong zhang
Postoperative Pain
Comparison of Two Drugs Bupivacaine and Ropivacaine for Postoperative Analgesia in Bilateral Superficial Cervical Plexus Block After Thyroidectomy
There is significant difference between bupivacaine and ropivacaine in terms of postoperative pain assessment in patients undergoing total thyroidectomy with bilateral superficial cervical plexus block.
- Trial name
- NCT07779551
- Testing
- Group 1 will receive 10ml of 0.25% bupivacaine, Group 2 will receive 10ml of 0.25% ropivacaine on each side.
- Where
- Pakistan
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Sargodha Medical College
Postoperative Pain, Inguinal Hernia
The Effect of Erector Spinae Plane Block on Quality of Recovery and Postoperative Analgesia After Inguinal Hernia Repair
Inguinal hernia repair (IHR) is one of the most commonly performed operations in general surgery practice. Different pharmacological approaches and interfascial plane blocks are used to control postoperative pain.
- Conditions
- Postoperative Pain, Inguinal Hernia, Acute Pain
- Trial name
- NCT04300153
- Testing
- ESP Block, Global Quality of Recovery-15 score, Standard Pain Followup and Monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Başak Altıparmak
Postoperative Pain, Postoperative Nausea
Serratus Plane Plus Pectoral I Block Versus Serratus Plane Block for Perioperative Analgesia in Breast Cancer Surgery
Breast cancer is the most common malignancy in women at worldwide. Even a minor breast surgery can cause significant postoperative pain (PP) (1). PP could be converted into chronic pain in 25-40% of cases.
- Conditions
- Postoperative Pain, Postoperative Nausea, Patient Satisfaction, Narcotic Use
- Trial name
- NCT03899545
- Testing
- Serratus Plane Block, Serratus Plane Block plus Pectoral I Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bezmialem Vakif University
Postoperative Pain, Vascular Access Device
Serratus Posterior Superior Intercostal Plane Block in Port Catheter Implantation
This randomized prospective study aims to compare the analgesic efficacy of serratus posterior superior intercostal plane (SPSIP) block and standard local anesthetic infiltration in patients undergoing port catheter implantation.
- Trial name
- NCT07579572
- Testing
- Serratus Posterior Superior Intercostal Plane Block, Local Anesthetic Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
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