Clinical trials: Analgesia, Postoperative
Midline Laparotomy
COMPARISON OF MEAN DURATION OF POST OPERATIVE ANALGESIA FOLLOWING ADDITION OF DEXMEDETOMIDINE TO ROPIVACAINE VERSUS PLAIN ROPIVACAINE ON ULTRASOUND GUIDED RECTUS SHEATH BLOCK
To compare the mean duration of postoperative analgesia following addition of dexmedetomidine to ropivacaine versus plain ropivacaine in ultrasound guided rectus sheath block in patients undergoing midline laparotomies
- Trial name
- NCT07254130
- Testing
- Rectus Sheath Block
- Where
- Pakistan
- Volunteers
- 209 people
- Sponsor
- Quaid-e-Azam Medical College
Postoperative Nausea and Vomiting, Surgery
The Application of Transversus Abdominis Plane Block Plus Rectus Sheath Block in Clinical Anesthesia
Peritoneal dialysis (PD) catheter placement surgery for patients with end-stage renal disease (ESRD) can be performed under peripheral nerve block.
- Conditions
- Postoperative Nausea and Vomiting, Surgery, Anesthesia, Peritoneal Dialysis
- Trial name
- NCT02984865
- Testing
- Sulfentanyl, Nalbuphine, flubiprofen axetil
- Where
- China
- Volunteers
- 190 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Hepatectomy
Effect of Epidural Anesthesia and Analgesia on Patients' Outcomes After Liver Resection
The purpose of this study is to analyze the effects of epidural anesthesia and analgesia on intraoperative clinical outcome, postoperative recovery, metabolic changes, and immune functions of the patients receiving open liver…
- Trial name
- NCT01617811
- Testing
- epidural anesthesia and analgesia
- Where
- China
- Volunteers
- 26 people
- Sponsor
- Sir Run Run Shaw Hospital
Postoperative Analgesia
Analgesic Effect of Ropivacaine Combined With Hydromorphone for CSEA After Total Knee Arthroplasty
The aim of this study is to investigate the continuous analgesic effect and side effects of ropivacaine combined with hydromorphone for combined spinal-epidural anesthesia(CSEA) after total knee arthroplasty and to explore its…
- Trial name
- NCT06205199
- Testing
- Hydromorphone was injected into the subarachnoid space
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Second Hospital of Jilin University
Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Open-heart Surgery
Serratus Posterior Superior Intercostal Plane Block for Postoperative Analgesia in Open-Heart Surgery
Postoperative pain following open-heart surgery is a significant challenge that may negatively affect recovery and overall clinical outcomes.
- Trial name
- NCT07232992
- Testing
- SPSIPB blcok, Parasternal blocks, Local Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Bursa City Hospital
Pain, Postoperative, Hip Pain Chronic
PENG Block Versus LP Block for THA Postop Pain
The purpose of this randomized, double blinded, prospective study is to compare the postoperative analgesia provided by the PENG block to that provided by the LPB for patients undergoing primary anterior approach THA.
- Trial name
- NCT05261009
- Testing
- Peri-capsular Nerve Group (PENG), Lumbar Plexus Block (LPB)
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Wake Forest University Health Sciences
Pain, Postoperative
Comparison of Local Anesthetic Dose in PENG Block Performed in Total Hip Replacement Operations
The investigators research was designed as a single-center, prospective, randomized double-blind study. The patients undergoing total hip replacement surgery in Istanbul University Istanbul Medicine Faculty Department of…
- Trial name
- NCT04900116
- Testing
- Bupivacaine HCl 0.5 % in 20 ML Injection, Bupivacaine HCl 0.25 % in 20 ML Injection, Bupivacaine HCl 0.125 % in 20 ML Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Brain Injury, Brain Tumors
Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy Surgery
Postoperative pain is prevalent after intracranial surgery. Patients undergoing craniotomy are typically managed with short acting opioids to enable early and reliable post-operative neurological exam as well as avoid the risk of…
- Conditions
- Brain Injury, Brain Tumors, Craniotomy Surgery, Pain
- Trial name
- NCT06810336
- Testing
- Remifentanil, Methadone
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Virginia
Lumbar Spinal Stenisis or Lumbar Herniated Intervertebral Disc
The Analgesic Effect of Nefopam on the Fentanyl Based PCA (Patient-controlled Analgesia) After Lumbar Spinal Surgery
Posterior lumbar spinal surgical pain leads to a severe degree of pain, and, hence, various means of pain management are required.
- Trial name
- NCT01808014
- Testing
- nefopam
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Postoperative Pain After Knee Arthroscopy
Effect of Pregabalin or Adductor Canal Block on Postoperative Analgesia
arthroscopically Anterior Cruciate Ligament Reconstruction (ACL) under spinal anesthesia were included in this study.
- Trial name
- NCT03530280
- Testing
- pregabalin (lyrica), adductor canal block including bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ankara Diskapi Training and Research Hospital
Postoperative Analgesia
Analgesic Efficacy of Ropivacaine Alone or in Combination With Adjuvants on Post-operative Analgesia Following Video-Assisted Thoracoscopic Surgery.
The aim of the study is to investigate the analgesic effects of the subcutaneous wound infiltration with tramadol, ketamine, dexamethasone, dexmedetomidine and midazolam as adjuvant to ropivacaine, compared to ropivacaine alone…
- Trial name
- NCT03809442
- Testing
- Ropivacaine + Ketamine, Ropivacaine + Tramadol, Ropivacaine + Midazolam
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- Aga Khan University
Postoperative Pain, Nephrolithiasis
A Randomized, Double-Blind, Placebo-Controlled Trial of Anrikefon for Postoperative Analgesia After Percutaneous Nephrolithotomy
This study evaluates whether a single dose of anrikefon, given intravenously shortly before the end of kidney stone removal surgery (PCNL), can reduce opioid-related side effects such as nausea, vomiting, itching, oversedation…
- Trial name
- ARK-PCNL (NCT07825142)
- Testing
- Anrikefon
- Volunteers
- 160 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Postoperative Pain Management
Efficacy of Intravenous Paracetamol and Ibuprofen on Postoperative Pain and Morphine Consumption in Hysterectomy
To compare the effects of intravenous paracetamol and ibuprofen on postoperative pain and morphine consumption in patients undergoing hysterectomy surgery and the side effects associated with opioids.
- Trial name
- ibupro-hyst (NCT04691856)
- Testing
- Morphine Sulfate, Intravenous paracetamol, Intravenous ibuprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Inonu University
Pain Management, Anaesthesia Complication
Efficacy of Variable Volume Truncal Blocks in Upper Limb Orthopedic Surgery
aim of this study is to compare the effect of selective truncal blocks, performed at different doses and volumes, on the onset times of motor and sensory blocks required for anesthesia in patients scheduled for hand, wrist…
- Trial name
- NCT06664203
- Testing
- Selective turuncus block with 25 ml bupivacain, Selective turuncus block with 15 ml bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Coxarthrosis, Pain, Postoperative
Lumbar ESPB in Hip Replacement Surgery
In this study, continuous erector spinae plane block (ESPB) will be compared to continuous epidural analgesia in patients undergoing elective hip replacement surgery.
- Conditions
- Coxarthrosis, Pain, Postoperative, Pain, Acute, Pain, Chronic
- Trial name
- ESPB_HIP (NCT06282666)
- Testing
- Spinal anesthesia, lumbar erector spinae plane block, Epidural analgesia
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Lublin
Pain, Post-operative
Evaluation of N1539 Following Abdominoplasty Surgery
The primary objective of this study is to evaluate the analgesic efficacy of N1539 in subjects with acute moderate to severe pain following abdominoplasty surgery.
- Trial name
- NCT02678286
- Testing
- N1539
- Where
- 4 sites in United States
- Volunteers
- 219 people
- Sponsor
- Baudax Bio
Postoperative Pain
Pain Control After Orthognathic Surgery
This study will assess the efficacy and safety of levobupivacaine for postoperative pain control in patients received orthognathic surgery.
- Trial name
- PCOGS (NCT01418183)
- Testing
- Trigeminal nerve block
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Total Hip Arthroplasty, Postoperative Pain
A Comparison of Postoperative Analgesic Nerve Block Ropivacaine Concentrations
Peripheral nerve blocks are the standard of care for pain management after hip replacement surgery at UPMC Shadyside. This prospective, randomized study is intended to assess the effect of 0.1 versus 0.2% ropivacaine in lumbar…
- Trial name
- NCT01556724
- Testing
- 0.1% or 0.2% ropivacaine nerve blocks
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Sylvia Wilson
Postoperative Pain Management During Rehabilitation in Patients Undergoing Total Knee Arthroplasty
A Clinical Trial to Evaluate the Safety and Effectiveness of OLIZ, a Photobiomodulation Medical Device for Surgical Site Pain Relief in Patients After Total Knee Arthroplasty
A Clinical Trial to Evaluate the Safety and Effectiveness of OLIZ, a Photobiomodulation Medical Device for Surgical Site Pain Relief in Patients After Total Knee Arthroplasty
- Trial name
- NCT07091773
- Testing
- OLIZ Photobiomodulation Device
- Volunteers
- 68 people
- Sponsor
- LTBIO Co., Ltd.
Diaphragm Paralysis Due to Local Anesthesia, Anterior Suprascapular Nerve Block
Anterior Suprascapular Nerve Block is an Effective and Diaphragm Protective Approach for Arthroscopic Shoulder Surgery
Interscalene block is still the gold standard in shoulder surgery analgesia. The most important side effect is diaphragm paralysis due to the phrenic nerve being affected.
- Conditions
- Diaphragm Paralysis Due to Local Anesthesia, Anterior Suprascapular Nerve Block, Analgesia, Arthroscopic Shoulder Surgery
- Trial name
- NCT04626869
- Testing
- Evaluation of Diaphragm Movement
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alper Tunga Dogan
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