Clinical trials: Analgesia, Postoperative
Postoperative Pain
Erector Spinae Plan Block for Postoperative Analgesia
Laparoscopic cholecystectomy is a widely employed procedure in ambulatory surgery. Pain after laparoscopic cholecystectomy arises significantly from port site incisions in the anterior abdominal wall.
- Trial name
- NCT03398564
- Testing
- Erector Spinae Plan Block, Oblique subcostal TAP
- Where
- Saudi Arabia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Al Jedaani Hospital
Anesthesia, Myomectomy
Improved Recovery Using Multimodal Peri-operative Analgesia in Minimally Invasive Myomectomy
The purpose of this study is to evaluate a multimodal analgesic protocol used in minimally invasive surgery for myomectomies (laparoscopic myomectomy (LM) and laparoscopically assisted myomectomy (LAM)).
- Trial name
- NCT00978601
- Testing
- Multimodal analgesic protocol during minimally invasive myomectomy
- Where
- Greece
- Volunteers
- 95 people
- Sponsor
- Iakentro Fertility Centre
Postoperative Pain
Ultrasound Guided Bilateral Erector Spinae Plane Block in Laparoscopic Cholecystectomy
This study will define the postoperative analgesic effect of ESP block via amount of patient-controlled analgesia (PCA) and postoperative analgesic consumption (such as routinely and rescue analgesics) and compare the control…
- Trial name
- NCT03391167
- Testing
- Ultrasound guided erector spinae plane block, Standard Pain Followup and Monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Pain, Postoperative
Local Analgesia to Prevent Pain in Patient Undergoing Removal of the Uterus Through Vaginal Route
Following a hysterectomy, women tend to experience high levels of pain, and many require strong pain killers after the procedure.
- Trial name
- NCT03099720
- Testing
- Ropivacaine
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Postoperative Pain
The Postoperative Analgesic Effect of Combination With Dexmedetomidine in Fentanyl-based Intravenous Patient Controlled Analgesia Compared With Conventional Thoracic Epidural and Intravenous Patient Controlled Analgesia After Radical Open Gastrectomy
The aim of this study to test hypothesis that addition of dexmedetomidine to fentanyl based intravenous patient controlled analgesia (PCA) improves postoperative pain compared with conventional thoracic epidural and intravenous…
- Trial name
- NCT02325882
- Testing
- Dexmedetomidine, Fentanyl 1, Fentanyl 2
- Where
- South Korea
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Pain, Postoperative, Serratus Anterior Plane Block
Comparison of Combined Serratus Anterior Plane Block and Thoracic Paravertebral Block
Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS.
- Conditions
- Pain, Postoperative, Serratus Anterior Plane Block, Thoracic Paravertebral Block, Multimodal Analgesia
- Trial name
- NCT05255562
- Testing
- Combined Serratus Anterior Plane Block, Thoracic Paravertebral Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Postoperative Pain, Narcotic Use
Postoperative Opt-In Narcotic Treatment Study
pills go unused, generating waste and leaving an opportunity for misuse and abuse. In a recent study, researchers let patients choose what medications to go home with after surgery.
- Conditions
- Postoperative Pain, Narcotic Use, Analgesia, Endocrine Surgery
- Trial name
- POINT (NCT04710069)
- Testing
- POINT
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Regional Anesthesia Morbidity, Postoperative Pain
Retrolaminar Thoracic Paravertebral Block
This clinical study will be conducted on female patients admitted to The General Surgery Department of Tanta Faculty of Medicine for a period of 9 months.
- Trial name
- NCT04162951
- Testing
- Ordinary approach paravertebral block, Retrolaminar paravertebral block
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Tanta University
Liver Failure, Acute Postoperative Pain
Modified Thoracoabdominal Nerve Plane Block In Living Liver Donors
Ultrasound-guided Modified Thoracoabdominal Nerve Plane Block (M-TAPA) is performed deep into the costochondral aspect at the 9th-10th costal level by injecting local anesthetics deep into the chondrium.
- Trial name
- NCT06300372
- Testing
- M-TAPA plane block, Postoperative pain management
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Medipol University Hospital
Hemorrhoids, Anal Fissure and Fistula
Pudendal Nerve Block With Bupivacaine Alone and Bupivacaine With Methylene Blue for Postoperative Analgesia
Study Description: The goal of this clinical trial is to compare the duration of postoperative pain relief achieved with two different approaches to pudendal nerve block in patients undergoing elective perianal surgery.
- Conditions
- Hemorrhoids, Anal Fissure and Fistula, Perianal Abscess, Perianal Fistula
- Trial name
- NCT05990569
- Testing
- Ultrasound guided Pudendal nerve block
- Where
- Nepal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nepal Mediciti Hospital
Lower Abdominal Surgery
Erector Spinae Plane Block for Peroperative Analgesia and Intraabdominal Tissue Oxygenation
Brief summary: Regional anesthesia decreases the need for intravenous analgesia in the peri-operative period. Erector spinae plane (ESP) is a regional anesthesia technique shown to be effective at the dorsal and ventral rami of…
- Trial name
- ESPB (NCT03808129)
- Testing
- Bupivacaine and Lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Pain, Postoperative
Exparel Injection for Postoperative Orbital Pain
After surgery to remove the eye, either by enucleation or evisceration, patients have variable levels of pain for several postoperative days.
- Trial name
- NCT02381353
- Testing
- Bupivacaine
- Where
- 2 sites in United States
- Volunteers
- 88 people
- Sponsor
- Mayo Clinic
Pain
Effectiveness of Celecoxib After Surgical Sperm Retrieval
While narcotic medication are commonly used for pain control near the time of surgery, there are significant side effects including constipation, nausea, risk of overdose leading to decreased breathing, and risk of addiction to…
- Trial name
- NCT01323595
- Testing
- Celecoxib, Sugar Pill
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Weill Medical College of Cornell University
Pain, Postoperative, Obstructive Sleep Apnea-hypopnea Syndrome
Postoperative Pain Management on Uvulopalatopharyngoplasty Patients
This is a randomized controlled study, aimed to investigate the effects of dinalbuphine sebacate (DS) on patients having uvulopalatopharyngoplasty (UPPP). DS is a prodrug of nalbuphine, a mixed agonist-antagonist opioid.
- Conditions
- Pain, Postoperative, Obstructive Sleep Apnea-hypopnea Syndrome, Pain, Acute
- Trial name
- NCT05825495
- Testing
- Dinalbuphine sebacate, Routine practice
- Volunteers
- 78 people
- Sponsor
- Li-Jen Hsin
Uniportal Video-assisted Thoracic Surgery
Optimization of Perioperative Analgesia Protocol for Uniportal Video-assisted Thoracoscopic Surgery
Trial design Despite video-assisted thoracic technology and procedure specific postoperative pain management (PROSPECT) have been promoted through recent years, thoracic surgery is still considered to be one of the most painful…
- Trial name
- NCT06016777
- Testing
- Ultrasound-guided paraspinal block and patient-controlled intravenous analgesia pump, Ultrasound-guided erector spinal block and patient-controlled intravenous analgesia pump, Patient-controlled intravenous analgesia pump
- Where
- China
- Volunteers
- 102 people
- Sponsor
- China-Japan Friendship Hospital
Lung Diseases
Continuous Erector Spinae Plane Block or Thoracic Epidural Analgesia Following Video Assisted Thoracic Surgery
Video assisted thoracic surgery (VATS) has recently been evaluated as the standard surgical procedure for lung surgery. Although VATS is less painful than thoracotomy, patients may feel severe pain during the first hours at…
- Trial name
- NCT03960736
- Testing
- ESP block (Group A), TEA group (Group B)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Medipol University
Analgesia
Opioid Free Anesthesia for Laparoscopic Cholecystectomy
The goal of this interventional study is to check the efficacy of Erector Spinae block as Opioid Free Anesthesia for Laparoscopic Cholecystectomy. Laparoscopic Cholecystectomy is a commonly performed day care procedure.
- Trial name
- NCT06202664
- Testing
- Erector Spinae Block, Opioid Analgesic
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Muhammad Haroon Anwar
Prostate Cancer
Qudratus Lumborum Block for Postoperative Pain After Endoscopic Prostatectomy.
Laparoscopic prostatectomy (LP) is characterized by substantial tissue trauma, despite its minimally -invasive approach. Although postoperative pain intensity is lower when compared to open procedures, the use of opioids is…
- Trial name
- NCT03600129
- Testing
- Qadratus Lumborum Block, 30 milliliters of 0.375% Ropivacaine, 30 milliliters of 0.9% NaCl
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Centre of Postgraduate Medical Education
Post-craniotomy, Pain
Pre-emptive Scalp Infiltration With Low-dose Flurbiprofen and Ropivacaine for Postoperative Analgesia After Craniotomy
Post-craniotomy pain is common and often associated with poor outcomes. Flurbiprofen axetil (FA) is an injectable NSAID for postoperative analgesia, however, the impact of local FA, remains elusive on post-craniotomy pain.
- Trial name
- NCT07209345
- Testing
- FA+Ropivacaine, Ropivacaine
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Beijing Tiantan Hospital
Postop Adult ICU Patients
Effect of Music on Pain and Anxiety After Surgery
Background: Studies have shown that listening to music can decrease pain and anxiety. Following surgery, patients in intensive care units (ICUs) often need drugs to treat their pain and anxiety.
- Trial name
- NCT01409044
- Testing
- Music
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
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