Clinical trials: Analgesia, Postoperative
Pain, Postoperative, Analgesia
Comparison of Postoperative Analgesic Efficacy of Caudal Block Versus Spinal Block With Levobupivacaine for Inguinal Hernia in Children
Neuraxial analgesia may improve postoperative outcomes for high-risk children who are susceptible to respiratory complications (e.g. post-operative apnea).
- Trial name
- NCT05117281
- Testing
- Levobupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Transversus Abdominis Plane Block
The Efficacy of Different Bupivacaine Concentrations in Pediatric Patients Undergoing Transversus Abdominis Plane Block
This study is designed to compare the analgesic efficacy of different bupivacaine concentrations in pediatric patients undergoing ultrasound-guided transversus abdominis plane (TAP) block for unilateral inguinal hernia repair.
- Trial name
- NCT04202367
- Testing
- 1 mg.kg-1 bupivacaine 0.25%, 1 mg.kg-1 bupivacaine 0.125%
- Volunteers
- 74 people
- Sponsor
- Istanbul University
Hip Osteoarthritis, Arthropathy of Hip
PENG Block vs PENG Plus Periarticular Injection vs Periarticular Injection in Older Adults
Pain after hip surgery is common in older adults and may limit early mobilization, increase the need for opioid medications, and contribute to complications such as delirium, nausea, or prolonged hospital stay.
- Trial name
- NCT07327892
- Testing
- Pericapsular Nerve Group (PENG) Block, Periarticular Injection (PAI)
- Where
- Poland
- Volunteers
- 108 people
- Sponsor
- Poznan University of Medical Sciences
Hip Fractures
Comparison of PENG Block and Fascia Iliaca Compartment Block in the Postoperative Pain Control of Hip Capsular Fracture
A prospective cohort study comparing PENG block versus iliac fascia block with the aim of evaluating its effectiveness in the peri-surgical analgesia of intracapsular femoral fracture.
- Trial name
- NCT05377541
- Testing
- Surgical treatment of femur fracture
- Where
- Spain
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de Terrassa
Postoperative Pain
Quadratus Lumborum Block vs Tranversus Abdominis Plane Block for Cesarean Section
The Quadratus Lumborum block (QLB) was first described by Blanco in 2007. The main advantage of QLB compared to the Transversus Abdominis Plane block (TAP) is the extension of local anesthetic agent beyond the TAP plane to the…
- Trial name
- NCT02489851
- Testing
- Quadratus Lumborum block, Tranversus Abdominis plane block
- Where
- United Arab Emirates
- Volunteers
- 76 people
- Sponsor
- Corniche Hospital
Postoperative Pain, Ultrasound Guided Nerve Block
Analgesic Efficacy of Trans-muscular Quadratus Lumborum Block After Unilateral Inguinal Hernia Repair
A significant component of pain experienced after abdominal surgery is related to incision of the abdominal wall and adequate analgesia can be a challenge.
- Trial name
- NCT03526731
- Testing
- ultrasound guided quadratus lumborum block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Breast Cancer, Postoperative Recovery
ERAS Protocols in Breast Conserving Surgery
Enhanced Recovery After Surgery (ERAS) protocols have been of increasing interest in the surgical community for decades. The emphasis has been development of protocols to maximize pain control post-operatively without the use of…
- Trial name
- ERAS (NCT06938581)
- Testing
- ERAS Protocol, Standard Perioperative Care
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- University of Nebraska
Regional Anesthesia Morbidity, Arthropathy of Hip
Comparison of PENG Associated with LFCN Block Versus FICB for Multimodal Analgesic Management in THA
Optimal pain control with limited muscle weakness is paramount for a swift initiation of physical therapy and ambulation. Fascia iliaca compartment block (FIC) has been recommended since it offers the best pain control with low…
- Conditions
- Regional Anesthesia Morbidity, Arthropathy of Hip, Hip Arthropathy, Post Operative Pain
- Trial name
- NCT06147401
- Testing
- PENG plus LFCN block, FIC Block
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- Ospedale Edoardo Bassini
Ultrasound, Transversalis Fascia Plane Block
Ultrasound-Guided Transversalis Fascia Plane Block Versus Caudal Block for Postoperative Analgesia in Children Undergoing Inguinal Herniorrhaphy
The aim of this study is to compare ultrasound-guided transversalis fascia plane block and caudal block for postoperative analgesia in children undergoing inguinal herniorrhaphy.
- Conditions
- Ultrasound, Transversalis Fascia Plane Block, Caudal Block, Postoperative Analgesia
- Trial name
- NCT06725667
- Testing
- Transversalis fascia plane block, Caudal block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Postoperative Analgesia
Effect of Paracetamol and Mannitol Injection on Postoperative Analgesia in Patients With Thoracoscopic Lobectomy
This study thoroughly evaluates the efficacy of acetaminophen mannitol injection for postoperative analgesia in patients undergoing thoracoscopic lobectomy, by comparing it with a control group.
- Trial name
- NCT06304181
- Testing
- Paracetamol and Mannitol Injection, Parecoxib
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Analgesic Drug Dependence
Intravenous Lidocaine for Perioperative and Postoperative Analgesia
Postoperative pain continues to be untreated despite the application of multimodal analgesia, medication and new analgesic techniques.
- Trial name
- NCT03921567
- Testing
- Lidocaine Hydrochloride, Lidocaine Hydrochloride and Ketamine
- Where
- 2 sites in Kosovo
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Rajmonda Nallbani-Komoni
Postoperative Pain
Association Between Patients' Perceptions of Success in Post-op Pain Management and Overall Experience With Care
Assessing the association between patients' perceptions of success with post-operative pain management and overall experience with care.
- Trial name
- NCT02389907
- Where
- 9 sites in United States
- Sponsor
- The Medicines Company
Stone, Kidney
Single-Shot With Dexmedetomidine Versus Continuous Ultrasound-guided Erector Spinae Plane Block for Postoperative Pain Control After Percutaneous Nephrolithotomy
The current study is designed to assess the efficacy of a single shot ESPB with Dexmedetomidineversus continuous ESPB in perioperative analgesia for PCNL. Both techniques are conducted for patients undergoing PCNL under GA.
- Trial name
- NCT04650737
- Testing
- single shot ESBP with dexmedtomidine, continous ESPB
- Volunteers
- 40 people
- Sponsor
- Cairo University
Hip Fractures, Hip Injuries
Iliopsoas Plane Block vs PENG Block for Hip Arthroplasty
Hip arthroplasty is one of the most common orthopedic procedures especially in elderly patients due to deformation of joints. Patients may complain of severe pain due to surgical trauma and prosthesis.
- Conditions
- Hip Fractures, Hip Injuries, Hip Arthropathy
- Trial name
- NCT05397145
- Testing
- Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Pain, Postoperative, Breast Cancer
Using Bupivacaine Locally in the Mastectomy Drains to Control Postoperative Pain
in this study we are investigating the role of instillation of Bupivacaine through surgical drains at the end of mastectomy surgeries in controlling post operative pain and decreasing their pain killers requirement in the early…
- Trial name
- NCT03799757
- Testing
- 40ml of 0.25% bupivacaine, 40ml of 0.9% normal saline
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Alexandria University
Kidney Stones, Urolithiasis, Hypocitraturia, Pain, Postoperative
Intertransverse Process Block Versus Erector Spinae Plane Block for Postoperative Analgesia After Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is the preferred minimally invasive procedure for renal stones larger than 2 cm, staghorn calculi and complex stone burdens, but it is frequently associated with moderate-to-severe…
- Trial name
- NCT07908992
- Testing
- Ultrasound-guided intertransverse process block, Ultrasound-guided erector spinae plane block
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Postoperative Pain
Posterior Quadratus Lumborum Block Using 0.125% Versus 0.25% Bupivacaine for Analgesia in Children Undergoing LPEC
The aim of the present study is to evaluate and compare the analgesic efficiency of the difference concentration between 0.125% and 0.25% bupivacaine provided by ultrasound guided posterior quadratus lumborum block undergoing…
- Trial name
- NCT04998071
- Testing
- Bupivacaine hydrochloride
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Queen Sirikit National Institute of Child Health
Molar, Third
Pain and Trismus Control in Third Molar Surgery: Ibuprofen, Ketamine, and Their Combination
The goal of the clinical trial is to compare the efficacy of ibuprofen, ketamine, and their combination in managing postoperative pain and trismus following third molar surgery.
- Trial name
- NCT05923775
- Testing
- Impacted third molar surgey
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Cihan Topan
Postoperative Pain
Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)
This is a Phase 3, randomized, double-blind, saline placebo- and active-controlled, multicenter study to evaluate the analgesic efficacy and safety of HTX 011 administered via local administration into the surgical site in…
- Trial name
- NCT03237481
- Testing
- HTX-011, Bupivacaine HCl, Luer-lock applicator
- Where
- 24 sites in United States, Belgium
- Volunteers
- 418 people
- Sponsor
- Heron Therapeutics
Postoperative Analgesia in Breast Reduction Surgery, Postoperative Pain
Comparison of Serratus Plane Block and Rhomboid Intercostal Plane Block for Postoperative Analgesia in Breast Reduction Surgery
This prospective, randomized clinical study aims to compare the analgesic efficacy of serratus plane block (SPB) and rhomboid intercostal plane block (RIPB) for postoperative analgesia in patients undergoing elective bilateral…
- Conditions
- Postoperative Analgesia in Breast Reduction Surgery, Postoperative Pain, Postoperative Pain Breast Reduction, Pain, Postoperative
- Trial name
- SAPB-RIPB (NCT07229092)
- Testing
- Serratus Anterior Plane Block (SAPB), Rhomboid Intercostal Plane Block (RIPB), No Regional Block (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Konul Karaja
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