Clinical trials: Analgesia, Postoperative
Analgesia, Postoperative
Comparison of Thoracic Epidural Analgesia and Intercostal Blockade in Patients Undergoing Thoracotomy
Postoperative pain is an important issue after thoracotomy operations. Thoracic epidural analgesia is most popular analgesic method, but sometimes it is not sufficient for pain.
- Trial name
- NCT03721250
- Testing
- epidural
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara University
Analgesia, Epidural, Pain, Postoperative
Programmed Intermittent Bolus Versus Continuous Infusion for Epidural Analgesia in Abdominal Surgery
Epidural analgesia is an efficient way to relieve pain after major abdominal surgery. Two different protocols are used to provide analgesia: continuous epidural infusion (CEI) and programmed intermittent boluses (PIEB).
- Trial name
- NCT04254523
- Testing
- Programmed intermittent epidural bolus (PIEB) of bupicavaine, Continuous epidural infusion (CEI) of bupivacaine, Continuous epidural infusion (CEI) of morphine
- Where
- Canada
- Volunteers
- 88 people
- Sponsor
- CHU de Quebec-Universite Laval
Postoperative Pain
TQL-block for Laparoscopic Hemicolectomy
Every year 350 patients undergo surgery due to colorectal cancer at Zealand University Hospital, Roskilde. The majority of the surgeries are performed using a minimal invasive laparoscopic technique where the bowl anastomosis is…
- Trial name
- NCT03570541
- Testing
- Ropivacaine, Acetaminophen, Patient controlled analgesia
- Where
- Denmark
- Volunteers
- 69 people
- Sponsor
- Zealand University Hospital
Pain, Postoperative
Safety and Efficacy of Intranasal Ketamine for the Treatment of Postoperative Dental Pain
Once patients' postoperative pain intensity reaches a moderate-to-severe level, they are randomized to receive intranasal ketamine or placebo.
- Trial name
- NCT00488787
- Testing
- intranasal ketamine
- Volunteers
- 40 people
- Sponsor
- Javelin Pharmaceuticals
Postoperative Pain
Comparison of Transversus Abdominis Plane Block and Erector Spinae Plane Block in Inguinal Hernia Repair
Multimodal analgesia is used to control postoperative pain in inguinal hernia repair. Transversus abdominis plane block is an effective regional anesthesia technique for postoperative analgesia in inguinal hernia repairs.
- Trial name
- NCT03515434
- Testing
- ESP Block, TAP Block, Standard Pain Followup and Monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Maltepe University
Acute Postoperative Pain, Non-steroidal Anti-inflammatory Drugs
Non-steroidal Anti-inflammatory in Cardiac Surgery
Non-steroidal anti-inflammatory drugs (NSAID) are part the multimodal strategy in pain management after surgery. However, major concerns are raised in cardiac surgery given the potential side effects of NSAID with more bleeding…
- Conditions
- Acute Postoperative Pain, Non-steroidal Anti-inflammatory Drugs, Cardiac Surgery, Pain Intensity
- Trial name
- KETOPAIN (NCT06381063)
- Testing
- pain management, ketoprofen
- Where
- France
- Volunteers
- 238 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pain, Postoperative
Comparison of Local Anesthetic Dose in PENG Block Performed in Total Hip Replacement Operations
The investigators research was designed as a single-center, prospective, randomized double-blind study. The patients undergoing total hip replacement surgery in Istanbul University Istanbul Medicine Faculty Department of…
- Trial name
- NCT04900116
- Testing
- Bupivacaine HCl 0.5 % in 20 ML Injection, Bupivacaine HCl 0.25 % in 20 ML Injection, Bupivacaine HCl 0.125 % in 20 ML Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Postoperative Pain, Cesarean Section
Effects of Nerve Blocks on Pain After Caesarean Section and Postpartum Depression
At the end of your cesarean section surgery, which is started by applying medication to the spinal cavity from your waist, pain medication will be applied between the relevant muscle and its covering from your lower abdomen or…
- Conditions
- Postoperative Pain, Cesarean Section, Postpartum Depression
- Trial name
- NCT06221280
- Testing
- Nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Pain, Acute, Hip Arthropathy
Safety of Ibuprofen After Major Orthopaedic Surgeries
Safety of an eight-day treatment with ibuprofen after primary hip and knee arthroplasties.
- Conditions
- Pain, Acute, Hip Arthropathy, Knee Arthropathy, Safety Issues
- Trial name
- PERISAFE (NCT05575700)
- Testing
- Ibuprofen
- Where
- 11 sites in Denmark
- Volunteers
- 2,904 people
- Sponsor
- Naestved Hospital
Arthroplasty, Replacement Material
Cryoneurolysis Prior to Total Knee Arthroplasty (CRYO-TKA Trial)
Approximately 20-30% of patients experience persistent pain after a Total Knee Arthroplasty (TKA). This study investigates whether percutaneous cryoneurolysis of genicular nerves can reduce pain and improve physical function when…
- Conditions
- Arthroplasty, Replacement Material, Knee Arthritis Osteoarthritis, Knee Arthroplasty, Total
- Trial name
- CRYO-TKA (NCT07425457)
- Testing
- CT-guided Cryoneurolysis of the Genicular Nerves
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Attikon Hospital
Pain
Oxycodone vs Fentanyl for Pain Treatment After Laparoscopic Cholecystectomy
To evaluate the analgesic efficacy of oxycodone and fentanyl in the treatment of postoperative pain after laparoscopic cholecystectomy.
- Trial name
- NCT00369811
- Testing
- Oxycodone, fentanyl
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Danish Pain Research Center
Lumbar Disc Herniation
An mTLIP Block for Analgesia Management After Lumbar Spinal Surgery.
Pain management is an important issue following lumbar spinal surgery. Wound infiltration is a technique that a local anesthetic solution is infiltrated into the tissues around the surgical area.
- Trial name
- NCT03967314
- Testing
- TLIP block group (group T), Wound infiltration group (group W)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Spondylolisthesis, Analgesia, Postoperative
Ultrasound-Guided Erector Spinae Plane Block for Postoperative Pain Control in Lumbar Spondylolisthesis Surgery
This clinical trial aims to evaluate the effectiveness of ultrasound-guided erector spinae plane (ESP) block as an adjunct to general anesthesia for managing postoperative pain in patients undergoing lumbar spondylolisthesis…
- Conditions
- Spondylolisthesis, Analgesia, Postoperative, ESPB
- Trial name
- NCT07514806
- Testing
- Control Group: General Anesthesia Without Erector Spinae Plane Block, Intervention Group: General Anesthesia With Ultrasound-Guided Erector Spinae Plane Block
- Where
- Bangladesh
- Volunteers
- 50 people
- Sponsor
- Bangladesh Medical University
Anesthesia
Rhomboid Intercostal Plane Block vs Local Anesthetic Infilteration for Postoperative Analgesia After Thoracoscopic Surgery
The purpose of the study is to evaluatethe effects of rhomboid intercostal block( RIB ) on postoperative pain after thoracoscopic surgery compared with local anesthetic infiltration ( LA )
- Trial name
- NCT04821947
- Testing
- Rhomboid intercostal plane block or Local anesthetic infiltration of 0.25% Bupivacaine
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Postoperative Analgesia in Patients Undergoing Open Renal Surgery
Ultrasound-Guided Midpoint Transverse Process to Pleura Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Patients Undergoing Open Renal Surgery :A Randomized Comparative Study.
The goal of this randomized comparative clinical trial is to compare the analgesic effectiveness of ultrasound-guided Midpoint Transverse Process to Pleura (MTP) block versus Erector Spinae Plane (ESP) block in adult patients…
- Trial name
- NCT07881523
- Testing
- Midpoint Transverse Process to Pleura (MTP)Block, Erector spinae plane (ESP) block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Minia University
Intervertebral Disc Prolapse
Pregabalin Compared to Gabapentin for Pain Control in Lumbar Disc Surgery
Pregabalin is claimed to have superior analgesic effect at lower doses and better pharmacological profile as compared to gabapentin esp. in perioperative pain control after major surgeries like intervertebral disc surgery.
- Trial name
- NCT02120703
- Testing
- Pregabalin, Gabapentin
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Aga Khan University
Anesthesia and Analgesia, Anesthesia, Endotracheal
Opioid Free Versus Opioid Balanced Anesthesia in Ophthalmic Surgery
Anesthesia without the use of opioid (Opioid free anesthesia) is an alternative to conventional opioid balanced anesthesia, with less post operative nausea and vomiting, and comparable analgesia.
- Trial name
- NCT06382831
- Testing
- Dexmedetomidine, Fentanyl
- Volunteers
- 104 people
- Sponsor
- Universitas Indonesia
Postoperative Pain
Postoperative Pain Relief After Cesarean Section: Is There a Role for the Quadratus Lumborum Block?
The Quadratus Lumborum block (QLB) was first described by Blanco in 2007. The main advantage of QLB compared to the Transversus Abdominis Plane block (TAP) is the extension of local anesthetic agent beyond the TAP plane to the…
- Trial name
- NCT02328378
- Testing
- Quadratus Lumborum block
- Where
- United Arab Emirates
- Volunteers
- 50 people
- Sponsor
- Dr. Tarek Ansari
Hernia, Ventral, Pain Management
Quadratus Lumborum Versus Placebo in Open Ventral Hernia Repair
The purpose of this study is to determine whether using a QL block is better than placebo (a look-alike substance that contains no drug) in lowering the amount of opioids you need for pain relief in the first 24 hours and if it…
- Trial name
- VHR (NCT06953635)
- Testing
- Quadratus Lumborum (QL) Block
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Tennessee Graduate School of Medicine
Pain, Postoperative
TAP Blockade for Pain Control in One-Anastomosis Gastric Bypass
Patients will be randomized into 2 groups: TAP: Patients undergoing TAP blockade, associated with intravenous Acetaminophen analgesia IV: Patients receiving only intravenous Acetaminophen analgesia Postoperative pain 24 hours…
- Trial name
- NCT03775018
- Testing
- Transversus abdominis plane blockade, Intravenous analgesia
- Volunteers
- 140 people
- Sponsor
- Hospital General Universitario Elche