Clinical trials: Analgesia, Postoperative
Analgesia
Postoperative Analgesia With an Erector Spinae Plane Block in Robotic-assisted Partial Nephrectomy
Partial nephrectomy is used as a standard method for the treatment of T1 kidney tumors, while radical nephrectomy is preferred for T2 tumors and localized masses that cannot be treated with partial nephrectomy.
- Trial name
- ESBPblock (NCT06928324)
- Testing
- Erector Spinae Plane block, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Hip Fractures
Circum-Psoas Blocks Versus Combined Lumbar and Sacral Plexus Blocks in Hip Fracture Surgery
Hip fracture (HF) is one of the major worldwide problems that constitute a significant mortality rate, ranging from 14- 36% in the first year after injury, and is associated with profound temporary and sometimes permanent…
- Trial name
- NCT05660603
- Testing
- control, LSP, CP
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Zagazig University
Surgery
Acupuncture for Postoperative Analgesia in Laparoscopic Surgery
Auricular (ear) acupuncture treatment involves placing filiform needles in the ears at particular locations called acupoints. Although the mechanism for acupuncture analgesia is still unclear, it is believed ear acupoints work…
- Trial name
- Acu-Pilot (NCT02940288)
- Testing
- Auricular Acupuncture
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Postoperative Pain, Intra-articular Injection
Comparison of Intra-articular Dexmedetomidine and Magnesium in Postoperative Pain
Arthroscopic meniscus surgeries are the most frequent orthopedic procedures. The objective of the study is to compare the effects of intraarticular local anesthetic and adjuvant (dexmedetomidine vs magnesium) combinations in…
- Conditions
- Postoperative Pain, Intra-articular Injection, Dexmedetomidine, Magnesium Sulfate
- Trial name
- NCT03479216
- Testing
- Precedex, Magnesium Sulfate
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Derince Training and Research Hospital
Pain, Pain, Postoperative
Opioid-Free Orthopaedics
The goal of this investigation is to compare effectiveness of this multimodal regimen at controlling postoperative pain with and without the use of opioid medications.
- Trial name
- NCT04659317
- Testing
- Oxycodone 5 mg Oral Tablet
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Emory University
Dexamethasone Adverse Reaction, Postoperative Pain
Role of Dexamethasone in Multimodal Analgesia for Postoperative Pain in Thoracic Surgery
The aim of the study is to evaluate the analgesic properties of dexamethasone and to quantify the possible associated postoperative complications, such as wound infections and hyperglycaemia, in patients who underwent lobectomy…
- Conditions
- Dexamethasone Adverse Reaction, Postoperative Pain, Postoperative Thoracic Procedure Complication, Analgesia
- Trial name
- NCT04325984
- Testing
- Dexamethasone
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- University of Trieste
Head and Neck Cancer, Pain, Postoperative
Stellate Ganglion Block in Head and Neck Cancer Surgery
The purpose of this study is to evaluate and reduce pain and improve quality of life in patients being treated for head and neck cancer with unilateral surgery.
- Trial name
- NCT03714906
- Testing
- Stellate ganglion block
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Augusta University
Parasternal Block, Serratus Anterior Plane Block
Combination of Parasternal and Serratus Anterior Plane Block in Coronary Artery Bypass Graft Surgery
Postoperative analgesia is a critical risk factor for the development of pulmonary and cardiovascular complications in coronary artery bypass graft (CABG) surgery.
- Conditions
- Parasternal Block, Serratus Anterior Plane Block, Acute Pain, Postoperative Analgesia
- Trial name
- NCT06326333
- Testing
- Combined parasternal block and serratus anterior plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ankara City Hospital Bilkent
Post-operative Delirium, Cognitive Dysfunction
Effect of Epidural Analgesia on Burst Suppression
It has been shown in previous studies that burst suppression has an effect on the development of postoperative delirium (POD) and postoperative cognitive dysfunction (POCD).
- Conditions
- Post-operative Delirium, Cognitive Dysfunction, Electroencephalography
- Trial name
- NCT05688449
- Testing
- Bupivacaine-fentanyl, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Bezmialem Vakif University
Postoperative Pain
Perioperative Lidocaine and Ketamine in Abdominal Surgery
The investigators propose to test the hypothesis that perioperative infusions of lidocaine and/or ketamine reduce opioid consumption and pain scores in adults recovering from elective inpatient abdominal surgery.
- Trial name
- NCT04084548
- Testing
- Lidocaine and ketamine, Lidocaine, Ketamine
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Anesthesia, Local
Bupivacaine Supplementation For Postoperative Pain Control In Surgical Removal Of Mandibular Third Molars
Control of postoperative pain is a foremost goal in achieving a satisfactory postoperative recovery. Surgical removal of lower third molars is accompanied by postoperative pain that is at its peak in the first 12 hours.
- Trial name
- NCT02353676
- Testing
- Bupivacaine, SALINE
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cosmozone Dental Clinic
Postoperative Pain, Cesarean Section
Intrathecal Morphine 75 mcg Versus 100 mcg for Post-Cesarean Analgesia: A Randomized Double-blind Trial
This study evaluates the efficacy and safety of two different doses of intrathecal morphine (75 mcg versus 100 mcg) for postoperative analgesia in patients undergoing elective cesarean delivery under spinal anesthesia.
- Conditions
- Postoperative Pain, Cesarean Section, Obstetric Anesthesia
- Trial name
- ITM-CESAREAN (NCT07516717)
- Testing
- Intrathecal Morphine
- Where
- Venezuela
- Volunteers
- 240 people
- Sponsor
- Hospital Universitario de Caracas
Dental Anxiety, Postoperative Pain
Effect of Alpha-Band Binaural Beats on Stress and Recovery in Third Molar Surgery
Preoperative anxiety and loud equipment noises, such as dental drills, create significant stress and autonomic fluctuations in patients undergoing oral surgery.
- Conditions
- Dental Anxiety, Postoperative Pain, Impacted Tooth, Binaural Beats
- Trial name
- NCT07881640
- Testing
- 10 Hz Alpha-Band Binaural Beats Track, Active Noise Cancellation (ANC)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Alperen Kalyoncu
Postoperative Pain
Intraperitoneal Ketamine Versus Fentanyl as Adjuvants to Bupivacaine in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is the standard surgical treatment for gallbladder stones; however, the origin of pain after LC is multifactorial and complex in nature.
- Trial name
- NCT07670052
- Testing
- Fentanyl, Ketamine
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Assiut University
Arthroplasty, Replacement, Hip
Multimodal Analgesic Regimen for Total Hip Arthroplasty: An Initiative to Minimize Postoperative Opioid Use
This study examines whether patients undergoing total hip replacement surgery can manage their pain effectively while using fewer opioid pain medications. Participants will be randomly assigned to one of two groups.
- Trial name
- NCT07672808
- Testing
- Standard Multimodal Analgesic Regimen with Opioid Prescription, Opioid-Reduced Multimodal Analgesic Regimen with Printed Prescription
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Henry Ford Health System
Postoperative Pain, Sternotomy
Preoperative Deep Parasternal Intercostal Plane Block and Intraoperative Opioid Use in Cardiac Surgery
Median sternotomy is commonly used in cardiac surgery and is associated with significant intraoperative and postoperative pain, often requiring substantial opioid administration.
- Conditions
- Postoperative Pain, Sternotomy, Opioid Consumption, Intraoperative Pain Control
- Trial name
- NCT07315308
- Testing
- Deep Parasternal Intercostal Plane Block, Standard Multimodal Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gaziantep City Hospital
Postoperative Pain, Pain
Comparison of Analgesic Efficacy of Intrathecal Bupivacaine Versus Bupivacaine Plus Dexmedetomidine in Patients Undergoing Orthopedic Surgeries.
Clinical Trial Overview: Intrathecal Bupivacaine vs. Bupivacaine + Dexmedetomidine Primary Objective Duration of Analgesia:** To compare the mean duration of postoperative pain relief between hyperbaric bupivacaine alone versus…
- Conditions
- Postoperative Pain, Pain, Orthopaedic Surgery, Anesthesia, Spinal
- Trial name
- NCT07866508
- Testing
- Dexmedetomidine plus Hyperbaric Bupivacaine, Hyperbaric bupivacaine % 0.5
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheikh Khalifa Bin Zayed Al Nahyan Combined Military Hospital Muzaffarabad
Postoperative Pain Management, Regional Anaesthesia
Midclavicle Block: A Clinical Observational Study
This prospective observational study aims to evaluate the effectiveness and safety of the ultrasound-guided Midclavicle Block (MCB) as an anesthetic and analgesic technique for midshaft clavicle fracture surgery.
- Conditions
- Postoperative Pain Management, Regional Anaesthesia, Ultrasound Guided, Clavicle Fracture
- Trial name
- MCB (NCT06905249)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital HM Nou Delfos
Pain, Postoperative
Usage of Tramadol With Levobupivacaine for Pain Treatment After Cesarean Section
Patients experience considerable amount of pain after cesarean section. The aim of this study is to investigate the effect of tramadol (an opioid pain killer) added to levobupivacaine (a local anesthetic) in continuous wound…
- Trial name
- NCT01916915
- Testing
- Tramadol infusion via wound catheter, Levobupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Ufuk University
Bariatric Surgery Candidate, Bariatric Bowel Surgery
Intravenous Lidocaine for Post-Operative Pain Control in Patients Undergoing Bariatric Bowel Surgery
Currently, there are no studies that address the optimum dosage of lidocaine for surgical procedures. Lidocaine is a local anesthetic that is injected to induce anesthesia.
- Trial name
- BSurg (NCT03095404)
- Testing
- Low Dose Lidocaine, High Dose Lidocaine
- Sponsor
- McMaster University
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