Clinical trials: Analgesia, Postoperative
Cesarean Section, Pain, Acute
Comparison of Intrathecal Morphine With the Quadratus Lumborum Type 2 Block for Post-operative Analgesia Following Elective Caesarean Section (QLBvITM Study)
The investigators are comparing post operative analgesia provided for caesarean section patients, with the quadratus lumborum type 2 block and intrathecal morphine.
- Trial name
- NCT03267628
- Testing
- Intrathecal morphine as well as local anaesthetic in Blocks, Intrathecal morphine as well as saline in Block, Saline intrathecal as well as saline in Blocks
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dr Willem Basson
Pain Management
Regional Block for Postoperative Free Flap Care
The purpose of this protocol is to evaluate the safety and efficacy of regional anesthesia for head and neck patients undergoing microvascular free flap reconstruction.
- Trial name
- NCT04080739
- Testing
- ropivicaine 0.2%
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Pain, Postoperative, Trauma
Reducing Pain and Anxiety During Dressing Changes After Burn Surgery Using Virtual Reality
Burn injury and its treatment is an intensely painful experience. Most severely injured patients require numerous dressing changes and skin grafting procedures (removing skin from healthy part of the body and moving it to damaged…
- Conditions
- Pain, Postoperative, Trauma, Burns
- Trial name
- BURN-360 (NCT04820400)
- Testing
- Immersive VR Video
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- Sunnybrook Health Sciences Centre
Pain, Acute, Hip Arthropathy
Safety of Ibuprofen After Major Orthopaedic Surgeries
Safety of an eight-day treatment with ibuprofen after primary hip and knee arthroplasties.
- Conditions
- Pain, Acute, Hip Arthropathy, Knee Arthropathy, Safety Issues
- Trial name
- PERISAFE (NCT05575700)
- Testing
- Ibuprofen
- Where
- 11 sites in Denmark
- Volunteers
- 2,904 people
- Sponsor
- Naestved Hospital
Lumbar Microdiscectomy Surgery, Lumbar Erector Spinae Plane Block
Comparison of the Analgesic Efficacy of Erector Spinae Plane Block in Lumbar Microdiscectomy Surgeries
Comparison of the Analgesic Efficacy of Lumbar Erector Spinae Plane Block and Sacral Erector Spinae Plane Block in Lumbar Microdiscectomy Surgeries
- Conditions
- Lumbar Microdiscectomy Surgery, Lumbar Erector Spinae Plane Block, Sacral Erector Spinae Plane Block, Postoperative Pain
- Trial name
- NCT07652177
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Current Smokers, Past Smokers
A Study on Analgesia and Related Outcomes for Patients With Tabacco Smoking
Numbers of postoperative PCA(Patient-Controlled Analgesia) related side effects among current, past and non smokers are determined by comparing and analyzing frequency distributions.
- Conditions
- Current Smokers, Past Smokers, Never Smokers
- Trial name
- NCT02266212
- Testing
- 5 ml arterial blood
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Craniosynostoses, Pain, Postoperative
Scalp Block Decreases Pain and Side Effects
Postoperative analgesia after corrective surgery of paediatric craniosynostosis is crucial in term of short and long-term outcomes.
- Trial name
- NCT04133467
- Testing
- scalp block
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Quality of Recovery
Effect of Nerve Block Under Ultrasound on Postoperative Prognosis in Children
The goal of this study was to compare the incidence of pain and recovery agitation after single-port laparoscopic inguinal hernia repair in children.
- Trial name
- NCT05820503
- Testing
- Ultrasound-guided lower abdominis rectus sheath block, Local anesthesia infiltration
- Where
- China
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Nantong University
Postoperative Pain
Anterior Abdominal Blocks for Postoperative Pain Control in Obese Patients
The purpose of this study is to compare between two surgical techniques for anterior abdominal wall blocks in obese patients Undergoing Major Gynecological Surgery: Surgical Transversus Abdominis Plane [TAP] block versus Rectus…
- Trial name
- NCT03732027
- Testing
- Surgical Transversus Abdominis Plane Block, Surgical Rectus Sheath Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Nausea, Vomiting
Effect of Dexamethasone Combined With Ondansetron on Postoperative Nausea and Vomiting in Patients With Patient-controlled Analgesia After Video-assisted Thoracoscopic Surgery
The purpose of this study is to study the effect of dexamethasone combined with ondansetron on postoperative nausea and vomiting in patients with patient-controlled analgesia after video-assisted thoracoscopic surgery.
- Trial name
- NCT01007500
- Testing
- Dexamethasone, Ondansetron
- Where
- South Korea
- Volunteers
- 123 people
- Sponsor
- Yonsei University
Postoperative Pain
Vaginal Wound Infiltration Analgesia for Postoperative Pain After Laparoscopic Hysterectomy: a Randomized Trial
In cases of laparoscopic hysterectomy , women were randomized to two groups: ropivacaine ( vaginal wound infiltration analgesia) vs. control group. Results regarding postoperative pain and need of oxycodone.
- Trial name
- NCT02767544
- Testing
- Vaginal wound local analgesia after laparoscopic hysterectomy
- Volunteers
- 81 people
- Sponsor
- Helsinki University Central Hospital
Nerve Block, Intercostal Nerve
Ultrasound-Guided Intercostal Nerve Block for Postoperative Pain Relief in Percutaneous Nephrolitotomy
Percutaneous nephrolitotomy (PCNL)is an endourological procedure for the management of patients with renal calculi. Postoperative pain around the surgical area and the nephrostomy tube can being a problem.
- Trial name
- NCT01549405
- Testing
- İntercostal nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Diskapi Teaching and Research Hospital
Postoperative Pain, Facial Swelling
Aescin-Based Herbal Extract (Reparil) for Postoperative Sequelae After Mandibular Third Molar Surgery
This randomized, single-blind, controlled clinical trial aims to evaluate the efficacy and safety of Aescin-based herbal extract (Reparil®) compared with Ibuprofen in managing postoperative sequelae following surgical removal of…
- Conditions
- Postoperative Pain, Facial Swelling, Trismus
- Trial name
- Reparil (NCT07244029)
- Testing
- Escin, Ibuprofen 400 mg
- Where
- Oman
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
To Assess the Beneficial Preemptive and Preventive Effects of PGL on the Immediate and Late (1- and 3 Months) Postoperative Analgesia Requirements
Pregabalin for Post-craniotomy Pain Control
Background: Proper pain relief is a major concern of patients worldwide. Preoperatively, one of the most common questions asked by patients pertains to the amount of pain they will experience after surgery how long it will last…
- Trial name
- NCT01612832
- Testing
- Pregabalin, Control
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Bupivacaine, Pain, Postoperative
Wound Infiltration of Liposomal Bupivacaine v Plain Bupivacaine for Post-Op Pain Control in Elective Cesarean Delivery
Randomized double blind placebo controlled trial to compare the post-operative pain control advantages of post-incisional wound infiltration with liposomal bupivacaine to plain bupivacaine in patients presenting for elective…
- Trial name
- NCT03353363
- Testing
- Bupivacaine, Liposomal bupivacaine
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Urinary Tract Diseases
Liposomal Bupivacaine for Postoperative Pain Control in Urologic Procedures
A prospective, randomized controlled study to determine the efficacy of liposomal bupivacaine given by local injection at all the wound sites in patients undergoing urologic surgeries.
- Trial name
- NCT02805504
- Testing
- Exparel, Marcaine
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Loma Linda University
Postoperative Analgesia, Total Hip Arthroplasty
Postoperative Analgesia After Total Hip Arthroplasty: Comparative Evaluation of Pericapsular Nerve Group Versus Fascia Iliaca Compartment Block
The aim of this study is to compare the effectiveness of pericapsular nerve group (PENG) block versus fascia iliaca compartment block (FICB) for postoperative pain relief following total hip arthroplasty (THA).
- Conditions
- Postoperative Analgesia, Total Hip Arthroplasty, Pericapsular Nerve Group Block, Fascia Iliaca Compartment Block
- Trial name
- NCT06003738
- Testing
- Fascia iliaca compartment block, Pericapsular nerve group block
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Ain Shams University
Intrathecal Dexmedetomidine, Pediatric Cancer Surgery
Intrathecal Dexmedetomidine Versus Fentanyl With Bupivacaine in Children Undergoing Major Abdominal Cancer Surgery
In this study the investigators aim to determine the analgesic effect and side effects of intrathecal fentanyl and dexmedetomidine as adjuvant to local anesthetics in pediatric patients undergoing major abdominal cancer surgeries.
- Trial name
- NCT02861716
- Testing
- Bupivacaine, Fentanyl, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- South Egypt Cancer Institute
Postoperative Pain Management, Laparoscopic Cholecystectomy
Peritoneal Lavage Using Saline or Saline With Ondansetron for Pain Control After Laparoscopic Cholecystectomy
Brief Summary Background: Laparoscopic cholecystectomy is a common procedure where postoperative pain and nausea/vomiting (PONV) remain significant issues, impairing recovery.
- Conditions
- Postoperative Pain Management, Laparoscopic Cholecystectomy, Ondansetron, Postoperative Nausea and Vomiting
- Trial name
- PLUSO (NCT06632184)
- Testing
- Ondansetron Intraperitoneal Lavage, Saline Intraperitoneal Lavage
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Instituto Mexicano del Seguro Social
Colonic Neoplasms, Diverticulosis, Colonic
Interest of the Nefopam and PCA Morphine Combination for Postoperative Analgesia in Patients Undergoing Colon Surgery
This study analyses interest of iv nefopam in combination with paracetamol after major abdominal surgery because the effect of morphine-sparing is discussed when combined these agents.
- Trial name
- NEFOPAM (NCT03619538)
- Testing
- Nefopam, saline solution
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
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