Clinical trials: Analgesia Disorder
Lumbar Disc Herniation, Postoperative Pain
Comparison of TLIP Block and QIP Block for Postoperative Analgesia After Lumbar Spine Surgery
This study compares two regional anesthesia techniques used for pain control after lumbar spine surgery: the classic thoracolumbar interfascial plane (TLIP) block and the quadratus lumborum-iliac plane (QIP) block.
- Trial name
- TLIP-QIP (NCT07750418)
- Testing
- Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Quadratus Lumborum-Iliac Plane (QIP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Vezirköprü State Hospital
Laparoscopic Cholecystectomy
Dexamethasone-Enhanced TAP Block in Lapchole
The transversus abdominis plane (TAP) block is widely used as part of analgesia for abdominal surgeries such as laparoscopic cholecystectomy. While bupivacaine is commonly used for TAP blocks with reported success.
- Trial name
- NCT07182110
- Testing
- Dexamethasone enhanced TAP Block, Marcaine- 0.25%
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Makassed General Hospital
Thoracotomy
Effect of Bupivacaine in Ultrasound-guided Erector Spinae Plane
To investigate the effect of two different volumes of bupivacaine 0.25% used in ultrasound-guided erector spinae plane (ESP) block on dermatome spread and postoperative analgesia in patients undergoing unilateral thoracotomy
- Trial name
- NCT03650335
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Yuzuncu Yil University
Music Therapy for Pain and Sedation, Neck Pain Musculoskeletal
Musical Mindfulness for Pain in the ED Waiting Room
Studies have shown that 60-70% of patients in the Emergency Department (ED) experience pain. With pain being such a broad issue in the ED, the ED is expected to deliver safe and effective treatment of pain.
- Conditions
- Music Therapy for Pain and Sedation, Neck Pain Musculoskeletal, Back Pain
- Trial name
- NCT07391891
- Testing
- Music intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Irvine
Breast Cancer
Modified Pectoral Nerve Block Versus Serratus Plane Block
In PECSII or modified PECSI block, local anesthetic (LA) is injected between pectoralis major muscle (PMm) and pectoralis minor muscle (Pmm) to block lateral and medial pectoral nerves and between pectoralis minor muscle (Pmm)…
- Trial name
- NCT04895397
- Testing
- ultrasound guided Nerve Block procedure
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Osteoarthritis
Patient Controlled Epidural Analgesia Versus Local Infiltration Analgesia Following Knee Arthroplasty
The purpose of this study was to determine if the method of peri-operative analgesia used following total Knee Replacement surgery affected the progress towards rehabilitation goals and to determine whether the analgesia had any…
- Trial name
- NCT02478372
- Testing
- Patient Controlled Epidural (PCEA), Local Infiltration Analgesia (LIA)
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Golden Jubilee National Hospital
Sedation, Preoperative Anxiety Experienced by the Pediatric Patient
Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery.
This study aims to compare intranasal dexmedetomidine versus intranasal ketamine as a premedication in children undergoing surgery in our population.
- Conditions
- Sedation, Preoperative Anxiety Experienced by the Pediatric Patient, Anxiolytic Effect, Sedation and Analgesia
- Trial name
- DREAM-Kids (NCT07180095)
- Testing
- Intranasal dexmedetomidine, Intranasal ketamine
- Volunteers
- 60 people
- Sponsor
- Liaquat National Hospital & Medical College
Pain Management
Bilateral Erector Spinae Plane Block in Paediateric Cardiac Surgery
ultrasound guided erector spinae plane block will be done for childern under going midline sternotomy for cardiac surgery. It is a novel block which is suspected to give powerful analgesia, decrease anaesthetic consumption and…
- Trial name
- NCT04168177
- Testing
- PCA, ESP
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Pain
Omnitram Pharmacokinetic and Analgesic Study Following CY2D6 Inhibition With Paroxetine In Healthy Volunteers
This study evaluates the analgesic effect of Omnitram and tramadol during concurrent administration of paroxetine. Paroxetine administration is expected to diminish the analgesic effect of tramadol, but not Omnitram.
- Trial name
- NCT03312777
- Testing
- Omnitram, Tramadol
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Syntrix Biosystems, Inc.
Lung Tumour, Lung Metastases
Study of Use of Paravertebral Blocks for Pain Relief in Video Assisted Lung Surgery
This project involves looking at the timing of providing pain relief for patients who are having lung surgery via the use of a small camera inserted into the chest with a scope (Video assisted thorascopy).
- Trial name
- ErLaPara (NCT01621698)
- Testing
- Early paravertebral block, Late Paravertebral block.
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University Hospitals Bristol and Weston NHS Foundation Trust
Temporomandibular Joint Disorders
Complementary Medicine Approaches to TMD Pain Management
This study will determine whether selected complementary approaches to temporomandibular joint (TMJ) pain management-acupuncture are as effective as usual care.
- Trial name
- NCT00010621
- Testing
- Acupuncture, chiropractic therapy, bodywork therapy
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
End-stage Renal Disease, Chronic Kidney Disease
Acupuncture for Pain Management of Hemodialysis Patients
The purpose of this study is to determine the feasibility, effectiveness and safety of acupuncture for pain management in hemodialysis patients.
- Trial name
- NCT01102816
- Testing
- Individualized acupuncture treatment, Routine care
- Where
- 2 sites in South Korea
- Volunteers
- 1 people
- Sponsor
- Korea Institute of Oriental Medicine
Temporomandibular Disorders (TMD)
Transcutaneous Electrical Nerve Stimulation for Early Pain Control in Temporomandibular Disorders
To evaluate whether adding conventional transcutaneous electrical nerve stimulation (TENS) to a standard conservative regimen (patient education, pharmacotherapy, and a home exercise programme) provides additional short- and…
- Trial name
- NCT07744893
- Testing
- Standard Conservative Therapy, Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Balikesir University
Pain, Postoperative, Pain, Acute
Opioid-free Anesthesia With a Mixture of Dexmedetomidine-lidocaine-ketamine
The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective laparoscopic…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Neuropathic
- Trial name
- NCT04858711
- Testing
- ketamine-lidocaine-dexmedetomidine, fentanyl
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aretaieion University Hospital
RDS of Prematurity, Surfactant Deficiency Syndrome Neonatal
Surfactant Administration by Insure or Thin Catheter
This trial evaluates the efficacy and safety of surfactant administration with thin catheter technique together with analgesic premedication in comparison with the established INSURE-strategy.
- Conditions
- RDS of Prematurity, Surfactant Deficiency Syndrome Neonatal, Analgesia
- Trial name
- SAINT (NCT04445571)
- Testing
- Thin catheter technique or standard ET-tube for surfactant administration
- Where
- Sweden
- Volunteers
- 160 people
- Sponsor
- Karolinska Institutet
Restlessness, Pain
Effects of Dexmedetomidine on Stress Response and Postoperative Analgesia
Dexmedetomidine is a highly selective α2 adrenoreceptor agonist approved by the US FDA for short-term postoperative sedation and analgesia.It can also reduce the stress response without respiratory depression.
- Trial name
- NCT01517932
- Testing
- dexmedetomidine
- Volunteers
- 60 people
- Sponsor
- Fang Luo
Humeral Fractures, Fractures, Closed
Pain Management in Children Undergoing Supracondylar Humerus Fracture Repair
The purpose of this study is to determine if US-guided supraclavicular anesthetic blocks reduce postoperative pain, use of rescue medication, and improve functional outcomes in children who underwent surgery for supracondylar…
- Trial name
- NCT01812863
- Testing
- Supraclavicular nerve block
- Where
- United States
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Analgesia
Efficacy and Safety of Lidocaine and Tetracaine Cream for Facial Laser Aesthetics in Chinese Adults
Lattice laser is a new medical cosmetic technology, which is a kind of noninvasive and invasive technology. Compared with traditional laser therapy, lattice laser has a wider range of clinical use, and can be used to treat skin…
- Trial name
- NCT05793892
- Testing
- Lidocaine tetracaine cream
- Where
- 11 sites in China
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Cutia Therapeutics（Wuxi）Co.,Ltd
Pain Management
Regional Block for Postoperative Free Flap Care
The purpose of this protocol is to evaluate the safety and efficacy of regional anesthesia for head and neck patients undergoing microvascular free flap reconstruction.
- Trial name
- NCT04080739
- Testing
- ropivicaine 0.2%
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Analgesia After ED Discharge for Extremity Injuries
Comparing the Efficacy of Oral Opioids for Outpatient Acute Pain Management After ED Discharge Discharge
There will be 3 randomized, double-blinded clinical trials to help determine which of commonly prescribed oral opioid combination is most effective in managing acute extremity pain after discharge from the adult emergency…
- Trial name
- NCT01402375
- Testing
- Hydrocodone (first trial), Codeine (first trial), Oxycodone (for second trial)
- Where
- United States
- Volunteers
- 720 people
- Sponsor
- Montefiore Medical Center