Clinical trials: Analgesia Post Fracture
Supracondylar Humerus Fracture
Supracondylar Humerus Fracture (SCHF) Post-Op Study Between Opioid and Non-Opioid Pain Management
This purpose of this study is to determine the efficacy of nonopioid versus opioid analgesic regimens following surgical fixation of Gartland Type III Supracondylar Humoral Fractures (SCHFs) to assist in the development of a…
- Trial name
- NCT06187584
- Testing
- Hydrocodone/acetaminophen, Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Children's Mercy Hospital Kansas City
Fracture, Pain, Postoperative
Methadone Versus Morphine for Orthopedic Surgery Patients
The investigators propose to compare analgesia by methadone and ketamine with a combination of morphine and ketamine in orthopedic surgery patients with moderate to severe pain.
- Trial name
- NCT00892606
- Testing
- Methadone, Morphine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Louisville
Elderly, Hip Fracture Surgery
Dexmedetomidine Supplemented Analgesia and Delirium After Hip Fracture Surgery
Delirium is common in the elderly after hip fracture surgery, and is associated with worse outcomes. The investigators hypothesize that, for elderly patients after hip fracture surgery, dexmedetomidine supplemented analgesia can…
- Conditions
- Elderly, Hip Fracture Surgery, Patient-controlled Analgesia, Dexmedetomidine
- Trial name
- NCT04955249
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Peking University First Hospital
Pain, Postoperative, Fracture, Ankle
Auricular Acupuncture as Part of Multimodal Analgesia After Lower Leg Fracture
The purpose is to find out if incorporation of an intraoperative electro auricular acupuncture protocol when added to a standard multimodal analgesic regimen for patients undergoing surgery to repair lower leg fracture under…
- Conditions
- Pain, Postoperative, Fracture, Ankle, Pilon Fracture of Tibia, Foot Fracture
- Trial name
- NCT05984433
- Testing
- Auricular acupuncture
- Where
- United States
- Sponsor
- Baylor College of Medicine
Fractures, Closed, Pain, Postoperative
Pain and Narcotic Usage After Orthopaedic Surgery
This study aims to 1) observe the course of pain, 2) utilization of opioid pain medication, and 3) possible effect of a behavioral intervention delivered via an automated mobile phone messaging robot in patients undergoing…
- Conditions
- Fractures, Closed, Pain, Postoperative, Pain Catastrophizing, Pain, Acute
- Trial name
- NCT03991546
- Testing
- Acceptance and Commitment Therapy Delivered via an Automated Mobile Messaging Robot
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Christopher Anthony
Delirium in Old Age
Erector Spinae Block and Incidence of Postoperative Delirium After Hip Fracture Surgeries
Postoperative pain is a significant risk factor for delirium. This clinical trial will search whether analgesia produced by erector spinae block in elderly patients undergoing hip fracture surgeries reduces delirium or not!
- Trial name
- NCT05819723
- Testing
- CAM score
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Hip Arthroplasty, Total, Postoperative Pain
Pericapsular Nerve Group Block Versus Intrathecal Morphine for Pain After Hip Surgery
Pain after hip replacement surgery is often severe and is commonly treated with opioids, which may cause nausea, vomiting, sedation, difficulty passing urine and slow breathing.
- Conditions
- Hip Arthroplasty, Total, Postoperative Pain, Hip Arthroplasty, Analgesia
- Trial name
- NCT07784192
- Testing
- Morpine, Ultrasound-guided pericapsular nerve group block, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Selcuk University
Postoperative Pain, Hip Fracture
Transcutaneous Nerve Stimulation for Post-operative Acute and Chronic Pain
Aim of the study to assess the efficacy of two modes of transcutaneous electrical nerve stimulation (TENS) on relief of postoperative acute pain after hip fracture surgery.
- Trial name
- NCT02642796
- Testing
- transcutaneous electric nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Mustafa Kemal University
Femur Fracture, Tibial Fractures
Postoperative Pain Management in Patients Undergoing Intramedullary Nail Fixation After Tibia and Femoral Fractures
The purpose of this trial is to determine whether oral acetaminophen and intravenous ketorolac are viable alternatives to opioid medication regimens for the pain management of patients with tibial and femoral shaft fractures…
- Trial name
- NCT04761302
- Testing
- Intravenous ketorolac and oral acetaminophen, Intravenous morphine and oral oxycodone
- Where
- Puerto Rico
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
Distal Radius Fracture
Randomized Controlled Trial Assessing the Effect of Dexamethasone on Postoperative Function After Distal Radius Fixation
The study is designed to assess the use of intraoperative dexamethasone on postoperative analgesia and stiffness after open reduction and internal fixation of distal radius fractures.
- Trial name
- NCT04889547
- Testing
- Dexamethasone, No dexamethasone
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Analgesia After Fracture Femur Surgeries
Comparing Erector Spinae and Fascia Iliaca Blocks for Pain Relief After Femur Surgery.
This clinical study compares two types of nerve blocks used to control pain in adult patients undergoing surgery on the upper (proximal) or middle (midshaft) part of the femur (thigh bone).
- Trial name
- NCT06990958
- Testing
- Erector Spinae Plane Block (ESPB) group, Fascia iliaca compartment block (FICB)
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Cairo University
Pain, Postoperative
The Effect of Femoral Nerve Block on Opioid Requirements After Surgery for a Femur Fracture in Children
This study evaluates the effect of a femoral nerve block on opioid requirements following femoral fracture fixation with flexible nails in the paediatric population. This is a double blind, prospective randomized clinical trial.
- Trial name
- NCT00175591
- Testing
- Administration of a femoral nerve block (bupivacaine HCL)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of British Columbia
Hip Injuries, Hip Fractures
Is the Rate of Early Mobilisation in Hip Fracture Patients Using Alfentanil Better Than Standard Opioid Analgesia?
Hip fracture injuries are linked with increased morbidity, frailty, and mortality risk. Studies have shown that in hip fracture surgery, early mobilisation confers better pain control, 30-day complication and mortality rates and…
- Conditions
- Hip Injuries, Hip Fractures, Pain, Post Operative Pain
- Trial name
- REHAB (NCT06212622)
- Testing
- Alfentanil, Oxycodone
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Postoperative Cognitive Dysfunction
The Influence of Postoperative Analgesia on Systemic Inflammatory Response and POCD After Femoral Fractures Surgery
The purpose of this study is to determine whether epidural levobupivacaine applied for the purpose of post-operative analgesia compared to systemic analgesia with morphine leads to better pain control, stronger suppression of the…
- Trial name
- NCT02848599
- Testing
- morphine, levobupivacaine
- Where
- Croatia
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Osijek University Hospital
Tibia Fracture, Femur Fracture
Bimodal Analgesia as Form of Pain Control Post Long Bone Fracture
The purpose of this prospective randomized study is to evaluate the risks and benefits of using bimodal analgesia, (i.e. Narcotics and NSAIDS) vs Narcotics alone post long bone fracture.
- Conditions
- Tibia Fracture, Femur Fracture, Humerus Fracture
- Trial name
- NCT00240396
- Testing
- Narcotics alone, Narcotics and NSAIDS
- Where
- United States
- Sponsor
- Beth Israel Deaconess Medical Center
Anesthesia, Conduction
Lateral Cutaneous Nerve and PENG Blocks Versus Suprainguinal Fascia Iliaca Block in Post-op Analgesia of Hip Fractures
Postoperative pain in hip fractures is challenging and requires adequate management. Peripheral nerve blocks are already known as superior than systemic analgesia in this scenario, but the best analgesic regional technique is…
- Trial name
- NCT05749367
- Testing
- Ropivacaine + saline solution, Saline solution + Ropivacaine
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Federal University of Minas Gerais
Hip Fractures
US-guided FICB After Hip Fracture: the Effect of the Local Anesthetic Volume on the Quality of Preoperative Analgesia
participants were randomly divided into three groups : group 30 , group 40 and group 50 . for all the three groups an ultrasound guided supra-inguinal fascia iliaca block had been performed.
- Trial name
- NCT04692857
- Testing
- supra inguinal fascia iliaca block
- Where
- Tunisia
- Volunteers
- 75 people
- Sponsor
- University Tunis El Manar
Orthopedic Surgery of Lower Extremity
Evaluation of Continuous Saphenous Nerve Block to Supplement a Continuous Sciatic Nerve Block After Ankle Surgery
A nerve block catheter is a small tube placed next to a nerve through a needle, and the needle is then removed. Numbing medicine is dripped through the tube to reduce pain sensation from the nerve.
- Trial name
- NCT01167907
- Testing
- 0.2% ropivacaine, saline
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Wake Forest University Health Sciences
Acute Post Operative Pain, Hip Fracture
Pain Relief Comparison: Pericapsular Nerve Group Versus Quadratus Lumborum Block for Positioning in Femur Fracture Surgery
This study aims to compare the analgesic efficacy of Ultrasound Guided Pericapsular Nerve Group Block and Quadratus Lumborum Block for pain relief During patient Positioning for Spinal Anesthesia in proximal femur fracture…
- Conditions
- Acute Post Operative Pain, Hip Fracture, Regional Anaesthesia, Quadratus Lumborum Block
- Trial name
- NCT06917807
- Testing
- Pericapsuler nerve group block, Quadratus lumborum block
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Ain Shams University
Fracture, Pain
Ibuprofen Versus Codeine. Is One Better for Post-operative Pain Relief Following Reduction of Paediatric Forearm Fractures?
For simple fractures treated in the emergency department with cast immobilisation only, ibuprofen has been shown to be superior to, or a least or equivalent to codeine with less side effects.
- Trial name
- NCT01605240
- Testing
- Acetaminophen and Ibuprofen, Acetaminophen and Codeine
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba