Clinical trials: Analgesia Post Fracture
Rib Fracture, Postoperative Pain
SPSIP vs ESP Block for Analgesia After Rib Fracture Surgery
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Serratus Posterior Superior Intercostal Plane (SPSIP) block and the Erector Spinae Plane (ESP) block in patients undergoing surgical…
- Conditions
- Rib Fracture, Postoperative Pain, Thoracic Trauma
- Trial name
- NCT07553208
- Testing
- Erector Spinae Plane Block (ESP), Serratus Posterior Superior Intercostal Plane (SPSIP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Abdominal Pain, Isolated Extremity Fracture
Morphine or Ketamine for Analgesia
Pain is common in children presenting to the emergency department but is frequently undertreated, leading to both short- and long-term consequences.
- Conditions
- Abdominal Pain, Isolated Extremity Fracture, Pain, Pediatrics
- Trial name
- MoKA (NCT06835504)
- Testing
- Ketamine hydrochloride, Morphine sulphate
- Where
- 8 sites in United States
- Volunteers
- 1,010 people
- Sponsor
- Columbia University
Post Operative Pain, Femur Fracture
Volume Dependent Effect of Pericapsular Nerve Block
In PENG block technique, the local anesthetic agent is injected between the psoas tendon and the pubic ramus to block the sensory branches of the nerves which innervates the hip capsule for providing analgesia without causing…
- Trial name
- NCT05256056
- Testing
- Bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Pain Management
Decreasing Unused Opioids in the Home Post Supracondylar Fracture Repair
Over the past two decades, the misuse of prescription opioids has significantly increased. A recent systematic review reported as much as 67% to 92% of opioids dispensed on discharge post-surgery go unused.
- Trial name
- NCT04059055
- Where
- Canada
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Upper Extremity Fractures, Analgesia Post Fracture
Oral Morphine Versus Ibuprofen
Children 5-17 years of age who have sustained a non-operative distal forearm (radius and/or ulna) or clavicular fracture will be randomized to receive either ibuprofen or oral morphine as needed for pain relief for the first 24…
- Trial name
- NCT01690780
- Testing
- Oral morphine, Ibuprofen
- Where
- Canada
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Naveen Poonai
Clavicle Fracture
Interscalene vs. Superficial Cervical Block vs. Combination for Analgesia After Clavicle Fracture
The optimal analgesic peripheral nerve block (or combinations thereof) are undefined for clavicle fractures, the most frequent fracture in the human population.
- Trial name
- NCT03094481
- Testing
- SCPB, ISB, SCPB + ISB
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Sunnybrook Health Sciences Centre
Femoral Neck Fracture
Postoperative Analgesia With Local Infiltration After Femoral Neck Fracture
Reducing pain is an essential factor for early mobilization after osteosynthesis of femoral neck fractures. Systemic opioids have side effects that might obstruct mobilization and induce delirium and nausea.
- Trial name
- NCT00529425
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Bimalleolar Fractures of the Ankle., Sciatic Nerve Block.
To Compare lidocaine2%/Clonidine in Combination, With Bupivacaine 0.5 % Alone in Equal Volumes for Combined Sciatic-saphenous Nerve Block in Terms of Selectivity of Blockade
Clonidine as an adjuvant to local anaesthetics prolongs the postoperative analgesia. It is predominantly an alpha 2 agonist, but does have some alpha 1 activity. Clonidine alone produces analgesia.
- Conditions
- Bimalleolar Fractures of the Ankle., Sciatic Nerve Block., Saphenous Nerve Block., Post Operative Analgesia Duration.
- Trial name
- NCT01759524
- Testing
- Bupivacaine, Lidocaine
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Cork University Hospital
Pain
Brachial Plexus Block in Post-Op Pain Control After Distal Upper Extremity Fracture: A Prospective Randomized Study
Despite the plethora of literature suggesting that regional blockade provides adequate andimproved postoperative pain control, function and improved intraoperative and postoperative safety in proximal upper extremity surgery…
- Trial name
- NCT01968824
- Testing
- Brachial Plexus Nerve Block
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Tibial Plateau Fractures
Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau
The investigators are conducting this research study to find better ways of treating pain following knee surgery. There is a standard (accepted) approach, which involves injection of numbing medication into the area around the…
- Trial name
- NCT06639503
- Testing
- Bupivacain
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Chicago
Hip Fractures (ICD-10 72.01-72.2), Postoperative Pain Management After Total Hip Arthroplasty
Effect of Preoperative PENG Block on Spinal Anesthesia Positioning and Postoperative Analgesia in Hip Fracture Surgery
Hip fractures are among the most common orthopedic traumas, particularly in elderly patients, and are usually associated with significant pain during positioning for spinal anesthesia.
- Conditions
- Hip Fractures (ICD-10 72.01-72.2), Postoperative Pain Management After Total Hip Arthroplasty, Elderly Patients, Regional Anesthesia
- Trial name
- PENG-SPINE (NCT07194356)
- Testing
- Pericapsular nerve group (PENG) block, Standard Spinal Anesthesia (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Acute Pain, Pain, Postoperative
Supraclavicular Blocks for Post-Operative Pain Control in Supracondylar Fracture Fixation, a Retrospective Analysis of Single Shot Catheter Techniques
We hypothesize that patients who receive a supraclavicular block via Angiocath, placed intra-operatively and dosed post-operatively following neurologic examination, will have lower pain scores, lower use of intravenous morphine…
- Trial name
- NCT02210429
- Testing
- Elbow Fracture Fixation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Hip Fracture Surgery, Postoperative Pain Management
Comparison of Sacral Erector Spinae Plane Block and Supra-Inguinal Fascia Iliaca Block for Analgesia After Hip Fracture Surgery
This study compares the postoperative analgesic effectiveness of Sacral Erector Spinae Plane Block (SESPB) and Supra-Inguinal Fascia Iliaca Block (SIFIB) in patients undergoing hip fracture surgery.
- Conditions
- Hip Fracture Surgery, Postoperative Pain Management, Regional Anesthesia, Elderly Patients
- Trial name
- NCT07081867
- Testing
- Supra-inguinal Fascia Iliaca Block (SIFIB), Sacral Erector Spinae Plane Block (SESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Hip Fractures, Pain, Postoperative
The Effect of TENS on Pain and Analgesic Consumption
The surgical treatment of an individual with osteoarthritis and hip fracture is provided by hip replacement surgery. While restructuring the joint surfaces with surgery, it is aimed to provide both hip joint movements and to…
- Conditions
- Hip Fractures, Pain, Postoperative, Analgesia
- Trial name
- NCT05939804
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University
Ankle Fractures, Distal Radius Fracture
Nerve Block for Pain Control After Fracture Surgery
Surgical treatment for patients with a fracture of the ankle or distal radius is commonly offered on an outpatient basis. Patients are routinely discharged from hospital within 4 hours of their procedure.
- Trial name
- NCT05391464
- Testing
- Peripheral Nerve Block
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- MaineGeneral Health
Rib Fractures
Early Percutaneous Cryoablation for Pain Control After Rib Fractures Among Elderly Patients
The purpose of this study is to provide long-term pain control for elderly patients with rib fractures in order to minimize their risk of complications and return them to baseline functional capacity
- Trial name
- EPERC (NCT04482582)
- Testing
- Cryoneurolysis, Standard of Care
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Stanford University
Postoperative Pain, Wrist Fracture
Comparing Efficacity of Analgesia Between Ultrasound-guided Nerve Block and Local Infiltration After Wrist Fracture Surgery
Distal radial fracture reparations by volar plating are often managed under regional anaesthesia, but are associated with severe pain when the block ends.
- Trial name
- BNINF (NCT02693288)
- Testing
- Local infiltration anesthesia
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Femoral Neck Fracture
Fascia Iliaca Block in the Emergency Department for Analgesia After Femoral Neck Fracture
Femoral neck fracture is very common in the elderly and can produce severe to moderate pain. As this pathology is not life-threatening, waiting time in the emergency department may be prolonged due to the high number of…
- Trial name
- NCT02433548
- Testing
- Fascia iliaca block
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Distal Radius Fracture, Pain Management
Narcotic Versus Non-narcotic Medication for Pain Management After Wrist/Hand Fractures
The purpose of this study is to evaluate two drug options for pain control in patients following wrist injury. Participants will be randomized to one of the 2 pain relief treatments to determine what treatment provides the most…
- Conditions
- Distal Radius Fracture, Pain Management, Metacarpal Fracture
- Trial name
- NCT03375593
- Testing
- Hydrocodone 5Mg/Acetaminophen 500Mg Tab, Acetaminophen 500Mg Tab, Ibuprofen 600 mg tab
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Closed Non Comminuted Long Bone Fractures
Continuous Lornoxicam Infusion for Orthopaedic Surgery
Perioperative continuous infusion of lornoxicam would be an effective and safe regimen to reduce the patient controlled morphine consumption after orthopaedic surgery.
- Trial name
- NCT01718756
- Testing
- Continuous infusion, Scheduled
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Mansoura University