Clinical trials: Analgesic
Failed Back Surgery Syndrome (FBSS)
Caudal Epidural With or Without Lumbar Sympathetic Block for Redo Lumbar Surgery
Comparing the analgesic effect of caudal epidural versus combined lumbar sympathetic block with caudal epidural in patients undergoing redo spinal surgery.
- Trial name
- CLEARS (NCT07199816)
- Testing
- Fluoroscopy-Guided Caudal Epidural Block, Combined Lumbar Sympathetic Ganglion Block and Caudal Epidural Block
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Hebatullah Mohammed Abdelmageed
Total Knee Arthoplasty, Knee Pain
TENS in Post-operative Total Knee Arthroplasty Recovery and Intra-venous Analgesics Requirement
Total knee arthroplasty (TKA) is among the major advancements for the treatment of knee pain and improvement of physical function when conservative management fails to comply with.
- Trial name
- NCT05470244
- Testing
- Routine Physical Therapy and Intra-venous analgesic regimen, Transcutaneous Electrical Nerve Stimulation along with Routine Physical Therapy and Intra-venous analgesic regimen
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Disorders of Consciousness, Severe Brain Injury
Use of Analgesic Treatment to Reduce Signs of Pain in Patients With Disorders of Consciousness.
The purpose of this study is to characterize and improve pain and nociception management in patients with disorders of consciousness (DOC).
- Conditions
- Disorders of Consciousness, Severe Brain Injury, Post-comatose Non-communicative Patients, Vegetative State
- Trial name
- NCT04330547
- Testing
- Analgesic administration
- Where
- Belgium
- Volunteers
- 19 people
- Sponsor
- University of Liege
Appendicitis
Peri-operative Analgesia for Single-incision Laparoscopic Appendectomy
Laparoscopic appendectomy is a very common intervention in pediatric surgery. To improve outcomes, some teams have developed the use of single-site laparoscopic appendectomy (SILAP).
- Trial name
- PAMAL (NCT05773521)
- Testing
- SILAP (single incision laparoscopic appendectomy)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Angers
Pain Management
Evaluation of the Efficacy and Onset of Action of a Topical Anesthetic Marker
The goal of this clinical trial is to to demonstrate the efficacy of a topical anesthetic in reducing pain during the performance of a painful test on the participant's arm.
- Trial name
- NCT07273916
- Testing
- Cutaneous marker (Transcutol P+ 20%, Tetracaine 7%, Lidocaine 23%, and dye q.s.),
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hexsel Dermatology Clinic
Pain
Could Algometric Assessment be Effective to Adjust Postoperative Analgesic Requirement?
The purpose of this study is to determine the correlation between preoperative algometer score and the amount of postoperative analgesic consumption.
- Trial name
- NCT02375607
- Testing
- Algometer
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Sickle Cell Disease
Assessment of Opioid Analgesia in Sickle Cell
To develop and validate a non-invasive, in vivo, phenotyping method for CYP2D6 using the non-injurious neuroselective electrical stimulation technique: pain perception threshold/pain tolerance threshold (PPT/PTT) in children and…
- Trial name
- NCT00513864
- Testing
- Dextromethorphan, Codeine, Morphine
- Where
- United States
- Sponsor
- Children's National Research Institute
Laparoscopic Cholecystectomy, Postoperative Pain
Subcostal TAP Block Versus Combined Subcostal TAP and Recto-Intercostal Fascial Plane Block for Analgesia After Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is commonly associated with moderate postoperative pain, particularly during the early postoperative period.
- Trial name
- NCT07869316
- Testing
- Subcostal Transversus Abdominis Plane Block, Recto-Intercostal Fascial Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Adductor Canal Block, Levobupivacaine
Single-shot Adductor Canal Block With Levobupivacaine and Dexmedetomidine in Total Knee Arthroplasty
Total knee arthroplasty surgery is associated with severe postoperative pain and adequate pain management is necessary for early postoperative mobilization and rehabilitation.
- Conditions
- Adductor Canal Block, Levobupivacaine, Dexmedetomidine
- Trial name
- NCT04968392
- Testing
- Dexmedetomidine Hydrochloride, Levobupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Pain
Requirement of Analgesics After Two Remifentanil Dosing Regimen in Cardiac Surgery.
Prospective double blind study comparing two remifentanil dosing protocols (0.1 and 0.3 mcg/kg/min) during cardiac surgery. Main outcome measures are postoperative opioid requirements (PCA oxycodone) and postoperative pain (VAS…
- Trial name
- REMISYD (NCT00757198)
- Testing
- remifentanil
- Where
- Finland
- Volunteers
- 90 people
- Sponsor
- Kuopio University Hospital
Neuropathic Pain
Study of Analgesic Action of Pregabalin, Duloxetine and Tramadol in Patients With Different Neuropathic Pain Phenotypes
Chronic pain is the most frequent cause from which millions of patients suffer worldwide, which makes them unable to work but also greatly affects their quality of life. Chronic pain is a condition in itself.
- Trial name
- NCT06252116
- Testing
- Pregabalin group, Duloxetine group
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aristotle University Of Thessaloniki
Analgesia, Renal Colic
Comparison of the Analgesic Efficacy of Dexketoprofen Trometamol, Meperidine, and Paracetamol in Renal Colic
This study aimed to compare the effectiveness of intravenous (IV) dexketoprofen trometamol, IV meperidine, and IV paracetamol as analgesics for renal colic in patients at the Emergency Department of Erciyes University Medical…
- Trial name
- NCT06558916
- Testing
- Dexketoprofen Trometamol, Meperidine Injectable Solution, Paracetamol
- Volunteers
- 90 people
- Sponsor
- Ismail Tekin
Pain Perception
The Effect of Combined Oral and Topical Analgesics to Reduce Pain Perception During Electrodiagnostic Testing
Electromyography (EMG) is a useful test for diagnosis and monitoring of lower motor neuron disorders. It is mostly done in conjunction with a Nerve Conduction Study (NCS).
- Trial name
- COMFORTEMG (NCT04337814)
- Testing
- EMLA Cream, Ibuprofen
- Where
- Pakistan
- Volunteers
- 113 people
- Sponsor
- Aga Khan University Hospital, Pakistan
Postoperative Pain
Different Concentrations of Bupivacaine in Erector Spinae Plane Block in Hip Surgeries
The prevalence of hip replacement surgery is increasing nowadays. Patients are usually older age and suffer from comorbidities may be an anesthetic and analgesic challenge.
- Trial name
- NCT04442750
- Testing
- Erector spinae plane block Technique, General anesthesia, Bupivacaine 0.5%
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Neuropathic Pain
Cortical Stimulation by Direct Current for the Treatment of Chronic Pain : Pilot-study of a Stimulation Device at Home
The purpose of this study is to confirm the analgesic effect of tDCS in neuropathic chronic pain, to estimate the importance and the duration of this effect, and to improve its efficiency by the use at home.
- Trial name
- STIMATHOME (NCT02346396)
- Testing
- tDCS (use at home)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Pain, Hip Fractures
Improving Pain and Function in Hip Fracture
The purpose of this study is to compare two different methods of treating pain after a hip fracture.
- Trial name
- NCT00749489
- Testing
- Femoral Nerve Block
- Where
- 3 sites in United States
- Volunteers
- 164 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Postoperative Analgesia, Lower Abdominal Cancer
Ketamine Versus Dexmedetomidine With Local Anesthetic in TAP Block
Comparing the analgesic effects of ketamine and dexmedetomidine when added to local anesthetic in TAP block for postoperative analgesia after lower abdominal cancer surgery.
- Trial name
- NCT03060070
- Testing
- Ketamine, dexmedetomidine, control group
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Pain
Analgesic Effect of Levobupivacaine in Breast Augmentation
The purpose of this study is to determine whether levobupivacaine is effective in the acute postoperative pain treatment in periprosthetic breast augmentation
- Trial name
- NCT02465008
- Testing
- Levobupivacaine
- Volunteers
- 66 people
- Sponsor
- General University Hospital of Valencia
Painful Diabetic Neuropathy (PDN), Diabetic Neuropathies
Efficacy of Topical Lidocaine Gel vs. Oral Duloxetine for Painful Diabetic Peripheral Neuropathy
The goal of this clinical trial is to learn if topical lidocaine gel can effectively reduce pain intensity compared to oral duloxetine in adult patients (aged 30-70 years) with type 2 diabetes suffering from painful diabetic…
- Conditions
- Painful Diabetic Neuropathy (PDN), Diabetic Neuropathies, Type 2 Diabetes
- Trial name
- NCT07800468
- Testing
- Topical Lidocaine 2% Gel, Duloxetine (60 MG)
- Volunteers
- 80 people
- Sponsor
- Wah Medical college , POF hospital
Postoperative Pain
Quadratus Lumborum Block vs Intrathecal Morphine for Post-Cesarean Analgesia
İn this study, planned to compare the post-operative analgesic efficacy of Intrathecal Morphine Administration and anterior Quadratus lumborum Block in elective cesarean section operations.
- Trial name
- NCT06612424
- Testing
- ANTERİOR QUADRATUS LUMBORUM BLOCK, İNTRATECHAL MORPHİNE GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
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