Clinical trials: Analgesic Effect
Total Knee Replacements
Analgesic Effect of Adding an Adductor Canal Block to a Femoral Triangle Block for Total Knee Replacement
The aim of the study is to investigate whether the addition of an adductor canal block to a femoral triangle block will provide better analgesia for patients after total knee replacements.
- Trial name
- NCT03461679
- Testing
- Adductor canal block, Femoral triangle block
- Where
- Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Changi General Hospital
Peri-tonsillar Analgesic Infiltration, Tonsillectomy
Tramadol Versus Lidocaine Infiltration for Tonsillectomy
The investigators postulate that the use of pre-incisional peritonsillar infiltration of tramadol or lidocaine reduces both the inflammatory response and postoperative analgesic consumption, without harmful effects.
- Conditions
- Peri-tonsillar Analgesic Infiltration, Tonsillectomy, Postoperative Pain, Inflammatory Response
- Trial name
- NCT01552096
- Testing
- peritonsillar infiltration
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Preemptive Analgesia
Analgesic Effect of Infraspinatus-teres Minor Block for Pre-emptive Analgesia in Patients Undergoing Shoulder Surgeries.
The aim of the study to evaluate the efficacy of the infraspinatus-teres minor (ITM) block in improving pre-emptive analgesia, reducing opioid consumption, and enhancing the overall analgesic effect in patients undergoing…
- Trial name
- NCT06999460
- Testing
- Infraspinatus teres minor block group, Control group
- Where
- 2 sites in Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postoperative Pain
Pre- Versus Post-incisional Pregabalin for Postoperative Pain Attenuation and Analgesics Spare in Orthopedic Oncologic Patients
Hypothesis No studies considered the comparison of preemptive vs. post-surgery Pregabalin (PGL) only administration. The investigators believe that the administration of PGL preemptively would diminish pain sensation and…
- Trial name
- NCT01359059
- Testing
- Pregabalin
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Postoperative Pain, Cryptorchidism
Comparison of Posterior QLB and QIPB in Pediatric Undescended Testis Surgery.
This randomized, double-blind study compares the postoperative analgesic efficacy of ultrasound-guided Posterior Quadratus Lumborum Block (QLB) versus Quadroiliac Plane Block (QIPB) in pediatric patients aged 1-7 years undergoing…
- Trial name
- NCT07426796
- Testing
- Ultrasound-guided Posterior Quadratus Lumborum Block., Ultrasound-guided Quadroiliac Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Medipol University
Postoperative Pain
Analgesic Effect of Intraoperative Esmolol in Mastectomies
This study aims to compare the quality of perioperative analgesia of esmolol in patients undergoing mastectomy.
- Trial name
- Esmobreast (NCT02466542)
- Testing
- Esmolol group
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital de Base
Post Operative Pain, Inflammation
Clinical and Biochemical Effects Of Cryotherapy Protocols On Mandibular Premolars With Symptomatic Apical Periodontitis
Pain is the major reason for patients' visits to dental clinics.Medications have side effects. Treatments including cryotherapy have been suggested to prevent these side effects.This study will compare the effect of oral and…
- Trial name
- NCT07138365
- Testing
- oral Cryotherapy, Intra radicular Cryotherapy, cold irrigation
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Osteoarthritis, Knee
Trial of Naproxen to Evaluate Various Methods of Measuring Analgesic Effect in Osteoarthritis Pain of the Knee
This study aims to evaluate various methods of measuring pain relief in subjects who have chronic OA of the knee. After a 1 week of wash-out from existing therapy, subjects will be treated in a blinded fashion for 1 week with…
- Trial name
- NCT01557816
- Testing
- Naproxen
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Analgesic Solutions
Pain
Evaluation of a TNF-Alpha Modulator for Clinical and Molecular Indicators of Analgesic Effect
This study will evaluate the role of thalidomide, a tumor necrosis factor (TNF)-alpha modulator, on severe inflammation and relief of pain following extraction of wisdom teeth.
- Trial name
- NCT00121563
- Testing
- Thalidomide, Ibuprofen or Diazepam
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Institute of Nursing Research (NINR)
Postoperative Pain
Adjuvant Analgesic Effects of Low Dose Tramadol/Acetaminophen Combination After Open Gynaecological Surgery
Patient experience moderate to severe pain after abdominal surgery. This post-operative pain can also contribute to complications such as respiratory impairment, cardiovascular events, ileus, sleep deprivation and mood…
- Trial name
- NCT00942565
- Testing
- tramadol/acetaminophen, acetaminophen
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Orthopedic Surgery, Pain, Postoperative
The Effect of Music Therapy on Pain Level and Analgesic Consumption
Pain is a common condition experienced by patients in long-term health care, rehabilitation and acute situations, due to various surgical interventions and invasive procedures, and postoperative pain is an important symptom…
- Conditions
- Orthopedic Surgery, Pain, Postoperative, Analgesia
- Trial name
- NCT05424211
- Testing
- Music Therapy Mobile Application
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cukurova University
Pain, Postoperative
Analgesic Efficacy of Plan Blocks in Laparoscopic Hysterectomies
Hysterectomy is the most common major intervention in gynecology after cesarean section. Indications include myoma uteri, abnormal uterine bleeding, cervical intraepithelial neoplasia, chronic pelvic pain, uterine uteri, operated…
- Trial name
- NCT05925972
- Testing
- Plane block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Pain, Hypnosis
Assessment in Healthy Volunteers of the Analgesic Effect Monitored by the NOL Index During Hypnotherapy Session
to evaluate, in healthy volunteers, the analgesic effect of medical hypnosis versus a state of calm watch during a thermal harmful stimulation and monitored by a quantitative, objective criterion and validated in the literature…
- Trial name
- HYPTHENOL (NCT04802239)
- Testing
- Medical hypnosis group, calm wake group
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Total Knee Arthoplasty, Knee Pain
TENS in Post-operative Total Knee Arthroplasty Recovery and Intra-venous Analgesics Requirement
Total knee arthroplasty (TKA) is among the major advancements for the treatment of knee pain and improvement of physical function when conservative management fails to comply with.
- Trial name
- NCT05470244
- Testing
- Routine Physical Therapy and Intra-venous analgesic regimen, Transcutaneous Electrical Nerve Stimulation along with Routine Physical Therapy and Intra-venous analgesic regimen
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Retrograde Intrarenal Surgery
The Effects Of Music In Retrograde Intrarenal Surgery
This study aimed to investigate the effect of music listening during the preoperative and postoperative stages in patients undergoing retrograde intrarenal surgery(RIRS) on basic life findings, anxiety, pain, and the amount of…
- Trial name
- NCT04500054
- Testing
- Music Listening
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Rectointercostal, Laparoscopic
Recto-intercostal Facial Plane Block in Laparoscopic Hiatus Hernia Repair
The aim of this study is to evaluate the perioperative analgesic and intraoperative hemodynamic effects of ultrasound-guided bilateral recto-intercostal fascial plane block in patients undergoing laparoscopic Hiatus hernia repair.
- Conditions
- Rectointercostal, Laparoscopic, Hiatus Hernia
- Trial name
- NCT06820216
- Testing
- Rectointercostal facial plane block using bupivacaine 0.25%, No Intervention as a control
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Procedural Pain
Analgesic Effect of Low Level Laser for Procedural Pain in Newborn Infants
Neonates undergo several painful procedures and these pain experiences can alter clinical outcome and behavior. The investigators aim to investigate the analgesic effect of low level laser for procedural pain during heel lancing…
- Trial name
- NCT03268148
- Testing
- LaserPen
- Where
- Taiwan
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Shoulder Pain
Postoperative Analgesic Effect of Infraspinatus-teres Minor Inter-fascial Block in Patients Undergoing Shoulder Surgery
It is proposed to investigate the effectiveness of ultrasound-guided intertrochanteric block of the infraspinatus minor round myofascial block not inferior to the interosseous groove brachial plexus nerve block in postoperative…
- Trial name
- NCT06240884
- Testing
- Infraspinatus-teres minor interfascial block, interscalene block
- Where
- China
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Jiaxing University
General Surgery
Inflammation and Postoperative Tramadol Analgesia
Patients will be admitted in the intensive care unit after major abdominal surgery. All patients will receive 100 mg of tramadol intravenously every 6 hours.
- Trial name
- NCT04330157
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- Osijek University Hospital
Acute Postoperative Pain, Tramadol Adverse Effect
Prospective Pharmacogenetic Cohort Study of CYP2D6 Metabolizer Phenotype, Analgesic Failure, and Adverse Effects in Postoperative Patients Receiving Tramadol by Elastomeric Infusion Pump
This prospective pharmacogenetic cohort will enroll postoperative patients receiving a standardized tramadol-containing elastomeric analgesia pump.
- Conditions
- Acute Postoperative Pain, Tramadol Adverse Effect, Pharmacogenetic Variation
- Trial name
- NCT07810816
- Testing
- Standardized Tramadol Elastomeric Analgesia Pump, CYP2D6 Genotyping and Metabolizer Phenotype Assignment
- Where
- Colombia
- Volunteers
- 200 people
- Sponsor
- Research Inc