Clinical trials: Analgesic Effect
Arthroscopy, Genicular Nerves Block
Adductor Canal Block Combined With IPACK vs Genicular Nerves Block in Knee Arthroscopy
This prospective randomized controlled study is designed to investigate the postoperative analgesic effect of adductor canal block (ACB) combined with infiltration of the interspace between the popliteal artery and the capsule of…
- Trial name
- NCT05269095
- Testing
- Spinal anesthesia only, Spinal anesthesia and ultrasound-guided Genicular nerves block, Ultrasound-guided Adductor Canal block (ACB) technique with infiltration of the interspace between popliteal artery and the capsule of posterior knee block ('PACK)
- Volunteers
- 105 people
- Sponsor
- Tanta University
Pain
Omnitram Pharmacokinetic and Analgesic Study Following CY2D6 Inhibition With Paroxetine In Healthy Volunteers
This study evaluates the analgesic effect of Omnitram and tramadol during concurrent administration of paroxetine. Paroxetine administration is expected to diminish the analgesic effect of tramadol, but not Omnitram.
- Trial name
- NCT03312777
- Testing
- Omnitram, Tramadol
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Syntrix Biosystems, Inc.
Lumbar Disc Herniation
Comparison of the Efficacy of Thoracolumbar Interfascial Plane Block and Erector Spina Plane Block in Lumbar Discectomy
Patients who will undergo herniated disc surgery have serious pain after surgery. In order to minimise this pain and to ensure that they recover more quickly and use less morphine-derived painkillers, we aim to apply two types of…
- Trial name
- NCT05999253
- Testing
- Modified thoracolumbar plane block (mTLIP), Erector spinae plane block (ESP)
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Musculoskeletal Pain
Analgesic Effect of a Biophotonic Foot Massage Cream
This study aims to evaluate the effectiveness of a biophotonic cosmetic massage cream in reducing musculoskeletal foot pain in adults.
- Trial name
- No acronym (NCT07501273)
- Testing
- Biophotonic cosmetic massage cream
- Volunteers
- 170 people
- Sponsor
- University of Seville
Surgery of Abdominoplasty With Flank Liposuction
Analgesic Effect Between TAP Block and Continuous Wound Infusion in Abdominoplasty Surgery
The purpose of this randomized controlled study is to compare the postoperative analgesic effect of a continuous wound infusion of local anesthetics and a sole transverse abdominal plan (TAP) regional block in the surgery of…
- Trial name
- NCT01862354
- Testing
- Transverse abdominal plan block, Continuous wound infusion
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University of Liege
Rib Fracture, Rib Fracture Multiple
Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Pain Following Thoracic Trauma
Thoracic trauma frequently involve rib fractures which can be very painful for 2-3 months. Unfortunately, pain is not simply a "symptom" of the injuries, but a significant cause of additional medical problems: pain causes people…
- Trial name
- NCT06069154
- Testing
- Cryoneurolysis, Local anesthetic peripheral nerve block
- Where
- 5 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of California, San Diego
Pain, Postoperative
Dexamethasone and Dexmedetomidine as an Adjuvant to Spinal Anesthesia for Elective Caesarean Sections
The main objective of our study is to evaluate analgesic effect of intrathecal dexamethasone and dexmedetomidine in elective caesarean sections
- Trial name
- NCT04697745
- Testing
- Intrathecal dexamethasone, Intrathecal dexmedetomidine
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Benha University
Neck Pain
Effects of Radio-frequency in Patients With Myofascial Chronic Neck Pain
The aim of this study was to evaluate the potential clinical benefits of Monopolar Capacitive Resistive Radio-frequency (448 kHz) (MCRR)F for the treatment of myofascial chronic neck pain.
- Trial name
- NCT02353195
- Testing
- Radiofrequency
- Volunteers
- 50 people
- Sponsor
- Universidad Rey Juan Carlos
Chronic Pain
Central Analgesic Drugs for the Treatment of Chronic Pain
Chronic pain is defined as pain that persists after healing of the wound that caused it, and can occur even in the absence of any obvious pathological trigger.
- Trial name
- NCT02223442
- Volunteers
- 300 people
- Sponsor
- University of Parma
Hysterectomy, Postoperative Pain
Postoperative Analgesic Effectiveness of the Modified Thoracoabdominal Nerve Block Through a Perichondrial Approach in Total Laparoscopic Hysterectomy
This single-center retrospective cohort study evaluated the effect of the modified thoracoabdominal nerves block through a perichondrial approach (M-TAPA) on postoperative analgesia in patients undergoing elective total…
- Trial name
- MTAPA-TLH (NCT07740252)
- Testing
- Modified thoracoabdominal nerves block through a perichondrial approach (M-TAPA)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Namik Kemal University
Analgesia, Inguinal Surgery
"Comparison of USG-Guided Caudal Versus Ilioinguinal/Iliohypogastric Nerve Block for Pediatric Inguinal Surgeries"
This study is designed to compare the analgesic effectiveness of caudal analgesia to ilioinguinal regional analgesia techniques in children undergoing inguinal surgeries.
- Conditions
- Analgesia, Inguinal Surgery, Undescended Testes, Hydrocele
- Trial name
- CAUCIN (NCT05558748)
- Testing
- USG-guided Caudal block, USG-guided Ilioinguinal/Iliohypogastric block
- Where
- Oman
- Volunteers
- 128 people
- Sponsor
- Sultan Qaboos University
General Anesthetic Drug Adverse Reaction
Effect of Tegileridine Versus Sufentanil as Analgesic Components on Opioid-Induced Cough During Anesthesia Induction
In patients undergoing general anesthesia with planned tracheal intubation , a prospective, randomized, controlled study was conducted to record the occurrence of cough 2 minutes after injection of Sufentanil or Tegilerdine.
- Trial name
- NCT07323043
- Testing
- Tegilerdine, Sufentanil
- Where
- China
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Lianyungang
Lower Abdominal Surgery
Comparison Between the Quadratus Lumborum Block ,Erector Spinae Plane Block in Lower Abdominal Surgery
the purpose of study is comparison between the analgesic effect of two techniques in adult lower abdominal surgeries
- Trial name
- NCT05524038
- Testing
- Bupivacaine Hydrochloride, Ultrasound device, Dexamethasone
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Fayoum University Hospital
Total Hip Arthroplasty
Analgesic Effect of the QLB-3 for Patients Undergoing a Total Hip Surgery
Total hip arthroplasty (THA) is one of the main elective orthopedic surgery. Recent studies have proven that patients undergoing an elective THA who are part of a fast track surgery program including an opioid free anesthesia…
- Trial name
- QLB-3 (NCT04555291)
- Testing
- Ropivacaine injection, NACL
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pain, Postoperative, Anaplasia
the Effect of Doctor-nurse-patient Cooperative Analgesic Linkage Program on Movement Evoked Pain
1. To establish doctor-nurse-patient cooperative analgesic linkage program. 2. Evaluate the effect of doctor-nurse-patient cooperative analgesic linkage program on movement evoked pain after laparotomy for patients with…
- Trial name
- NCT03823846
- Testing
- Routine Dezocine injection, Adjusted Dezocine injection, Routine Dynastat or Flurbiprofen Axetil jinjection
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pain
Characterization of the Analgesic Effect of CBD in Healthy, Normal Volunteers
The purpose of this double-blind, placebo-controlled study is to determine the analgesic effects of cannabidiol (CBD), a chemical constituent found in cannabis that does not have intoxicating effects.
- Trial name
- NCT02751359
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Hypospadias, Caudal Block
Ultrasound Guided Sacral Erector Spinae Plane Block Versus Ultrasound Guided Caudal Block in Pediatric Undergoing Hypospadias Surgery
Randomized, parallel-group, assessor-blinded clinical trial at Tanta University Hospitals comparing ultrasound-guided sacral erector spinae plane block (sESPB) versus ultrasound-guided caudal epidural block for postoperative…
- Conditions
- Hypospadias, Caudal Block, Erector Spinae Plane Block, Pain, Postoperative
- Trial name
- NCT07099560
- Testing
- Ultrasound-guided sacral erector spinae plane block (sESPB), Ultrasound-guided caudal epidural block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Low Back Pain
Morphine Versus Ketorolac in Low Back Pain
The study is prospective, double blinded, randomised controlled and has the purpose to compare the analgesic effects of ketorolac or morphine intravenous in low back pain.
- Trial name
- NCT02782286
- Testing
- Ketorolac, Morphine
- Volunteers
- 100 people
- Sponsor
- Loredana Ghinea
Analgesic Drugs, Antinociceptive Agents
Analgesic Effects of Midazolam in Human Volunteers
This study evaluates analgesic properties of midazolam compared to placebo and fentanyl. Each participant will receive all three drugs (midazolam, fentanyl, placebo) on three different occasions (study visits) and the effect on…
- Trial name
- GabA01 (NCT02629146)
- Testing
- Midazolam, Fentanyl, Isotonic saline
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Wilhelminenspital Vienna
Thoracotomy, Thoracotomy Analgesia
Compare the Perioperative Analgesic Effect of Ultrasound Guided Thoracic Paravertebral Block and Ultrasound Guided Serratus Anterior Block in Patients Undergoing Thoracotomy
The aim of this study is to compare the perioperative analgesic effect of ultrasound guided thoracic paravertebral block and ultrasound guided serratus anterior block in patients undergoing thoracotomy.
- Trial name
- thoracotomy (NCT06831578)
- Testing
- seratuse anterior plane block, paravertebral plane block
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Menoufia University