Clinical trials: Analgesic Effect
Postoperative Pain
The Analgesic Effect of Transversus Abdominis Plane (TAP) Block Following Radical Prostatectomy
This study is conducted to evaluate different analgesic treatments effect following operation where the prostate gland is surgically removed. The different treatments the investigators wish to investigate is: 1.
- Trial name
- NCT01317368
- Testing
- Naropine
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Postoperative Pain
Comparing the Effects of M-TAPA and TAP Block on Postoperative Analgesia in TAH
Aim is to compare the postoperative analgesic efficacy of M-TAPA block and TAP block and their effect on opioid consumption in patients undergoing open total abdominal hysterectomy (TAH) surgery.
- Trial name
- NCT05901090
- Testing
- M-TAPA block, TAP block
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Cumhuriyet University
Kidney Transplant Recipient, Kidney Transplant Donor
Investigation of the Effects of Quadratus Lumborum Block Applied to Patients in Kidney Transplant Surgery
This study aims to determine the most effective and long-lasting pain relief method for post-operative analgesia in kidney donor and recipient patients in kidney transplantation programme with the least invasive and least drug…
- Trial name
- NCT06011850
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Chronic Low Back Pain
Pain Detecting and Analgesic Stimulating Device on Low Back Pain
Purpose of study is to test in a randomized controlled trial (RCT) the effects of the Nervomatrix device on various clinical outcomes of patients with low back pain, as well as its mechanisms of action.
- Trial name
- NCT02256410
- Testing
- Stimulation
- Where
- Belgium
- Volunteers
- 39 people
- Sponsor
- Vrije Universiteit Brussel
First Trimester Abortion, Surgical Abortion
The Effect of Music Therapy Under Ultrasound Guided Manual Vacuum Aspiration
Manual vacuum aspiration (MVA) is one of the surgical treatment options for managing early pregnancy loss. When compared to traditional surgical method; MVA is safer, more cost-effective, due to its shorter hospitalisation period…
- Conditions
- First Trimester Abortion, Surgical Abortion, Music Intervention, Local Anesthesia
- Trial name
- NCT04708808
- Testing
- music therapy
- Where
- Hong Kong
- Volunteers
- 176 people
- Sponsor
- Chinese University of Hong Kong
Analgesic Affect
A Study to Test the Pain-relieving Effect of Laughing Gas in Infants
Our proposal is to study infants in the Neonatal Intensive Care Unit (NICU) who are undergoing a heel stick for blood sampling, a standard procedure in patient care.
- Trial name
- NCT00250692
- Testing
- Nitrous Oxide
- Where
- United States
- Sponsor
- University of California, Los Angeles
Healthy, Inflammation
Using a Narcotic to Enhance the Numbing Effect of the Local Anesthetic Lidocaine on Inflamed Molar Teeth
The effectiveness of local anesthetics is reduced if inflammation is present, making it difficult to control pain during such procedures as root canals and wisdom teeth removal.
- Conditions
- Healthy, Inflammation, Mouth Disease, Pain
- Trial name
- NCT00001952
- Where
- United States
- Volunteers
- 275 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Non-Vital Tooth
Piroxicam Premedication for Postendodontic Pain in Non-vital Mandibular Molars
The aim of the study is to evaluate the effect of piroxicam (20mg) compared to placebo on post-endodontic pain of single-visit endodontic treatment of non-vital mandibular molars.
- Trial name
- NCT03998826
- Testing
- Piroxicam
- Volunteers
- 60 people
- Sponsor
- Cairo University
Anesthesia
Comparison of Analgesic Effect of Volatile Anesthetics
The purpose of this clinical trial is to compare analgesic effect of sevoflurane and desflurane at equal minimum alveolar concentrations using surgical pleth index.
- Trial name
- NCT02830243
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Kangbuk Samsung Hospital
Lateral Epicondylitis
Shock Wave Therapy in Individuals With Lateral Epicondylitis
A sample of 40 patients poststroke (24 males) was randomly allocated to either ESWT experimental (n=18) or conventional physiotherapy control group (n=20). All patients received 5 sessions during the treatment program.
- Trial name
- NCT05142852
- Testing
- Extracorporeal shock wave therapy, Conventional physiotherapy
- Where
- Jordan
- Volunteers
- 43 people
- Sponsor
- Salameh Aldaja
Chronic Sinusitis
Intraoperative and Post-operative Analgesic Effect of IV Acetaminophen for Sinus Surgery
The purpose of this study is to assess the use of IV acetaminophen (Ofirmev) as a and safe and efficacious agent in reducing post-operative pain; we hypothesize that its use will reduce post-operative pain when compared to a…
- Trial name
- IVAPAP (NCT01608308)
- Testing
- IV Acetaminophen
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- The University of Texas Health Science Center, Houston
Postoperative Pain
Lumbar Erector Spinae Plane Block and Quadratus Lumborum Block in Hip and Proximal Femur Surgeries
Multimodal analgesia is used to control postoperative pain in hip surgery. Quadratus lumborum block is an effective regional anesthesia technique for hip and proximal femur surgery.
- Trial name
- NCT03508544
- Testing
- Lumbar ESP block, QLB bLock, Standard Pain Followup and Monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Maltepe University
Pain, Neuropathic Pain
Study to Evaluate Efficacy, Safety, Tolerability and Pharmacokinetics of AZD1386 in Patients With Peripheral Neuropathic Pain
The primary aim of this study is to investigate if AZD1386 is efficacious as an analgesic in patients with peripheral neuropathic pain.
- Trial name
- AVANT (NCT00976534)
- Testing
- AZD1386
- Where
- 12 sites in Canada, Denmark and 2 more
- Volunteers
- 90 people
- Sponsor
- AstraZeneca
Knee Arthroscopy, Acute Pain
"Comparison of Intra-articular of 0.2% Ropivacaine vs. 0.75% Ropivacaine in Postoperative of Knee Arthroscopy"
All patients with acute lesions that attend the orthopedic and trauma center of the ABC medical center are invited to participate in the study.
- Trial name
- ropivacaine (NCT05807945)
- Testing
- Ropivacaine 0.75% Injectable Solution, Ropivacaine 0.2% Injectable Solution
- Where
- Mexico
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Paola M Zamora Munoz
Pain, Postoperative, Ketamine Adverse Reaction
Neuropsychiatric and Cardiovascular Side Effects in Ketamine Analgesic Infusions
Evaluation of neuropsychiatric and cardiovascular side effects of low dose ketamine analgesic infusion for postoperative pain
- Trial name
- NCT03525912
- Testing
- Ketamine
- Where
- Colombia
- Volunteers
- 101 people
- Sponsor
- Universidad de Antioquia
Pulpitis - Irreversible
Analgesic Effect of Low Intensity Laser in Patients With Pulpitis of Mandibular Molars.
The present study has the objective of evaluating whether the previous therapy with low intensity laser, through its analgesic effect, can promote a greater comfort specifically for patient with pulpitis in mandibular molars.
- Trial name
- NCT03553407
- Testing
- Low Level Laser - Pulse, Low Level Laser - continuous
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Anesthesiology, Percutaneous Coronary Intervention
Ultrasound-Guided Transversus Abdominis Plan (TAP) Block in Endovascular Cardiac Interventions
Sensory innervation of the femoral region which is the entry point for endovascular cardiac interventions such as coronary angiography,cardiac catheterization and percutaneous coronary intervention is complex.It is thought that…
- Conditions
- Anesthesiology, Percutaneous Coronary Intervention, Cardiac Catheterization, Analgesia
- Trial name
- NCT06576128
- Testing
- ultrasound, parenteral local anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University - Cerrahpasa
Postoperative Pain
Comparison of Analgesic Effects of TAP Block and RSB in RALPs
In this research, we aim to compare the postoperative analgesic efficacy of these two peripheral blocks in patients undergoing RALP who have received preoperative TAP block and RSB block.
- Trial name
- NCT06681571
- Testing
- TAP Block, RSB
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Gastric Cancer, Postoperative Pain
Comparison of the Postoperative Analgesic Effects of the Temperature-responsive Gel Mixed With Local Anesthetics Application and Ultrasound-guided Transversus Abdominis Plane Block in Patients Undergoing Laparoscopic Gastrectomy
This study is a single-center, prospective, randomized controlled trial designed to compare two established postoperative analgesic strategies in adult patients undergoing laparoscopic gastrectomy under general anesthesia.
- Trial name
- TAP-WELPASS (NCT07452471)
- Testing
- Ultrasound-guided Transversus Abdominis Plane (TAP) Block, Ropivacaine-Poloxamer 407 Hydrogel (Welpass®)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Gyeong-Jo Byeon, MD, PhD
Video Assisted Thoracoscopic Surgery, Lobectomy
SERRATHOR TRIAL : Interest of the Novel Serratus Plane Block in Post Operative Analgesia After Video-Assisted Thoracoscopic Lobectomy
Pain after thoracic surgery remains a challenge for anesthetists. Although VATS for lobectomy is associated with fewer complications compared to thoracotomy, pain after VATS needs to be treated with opioids.
- Conditions
- Video Assisted Thoracoscopic Surgery, Lobectomy, Pain Post Operative, Regional Anesthesia
- Trial name
- SERRATHOR (NCT03867695)
- Testing
- Ropivacaine, sterile saline
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France