Clinical trials: Analgesic Effect
Pain, Postoperative, Analgesics, Opioid
Evaluation of Abdominal Wall Block With Liposomal Bupivacaine for Post-Operative Analgesia in Donor Nephrectomy
A blinded randomized control trial in living kidney donors. The study group will receive a liposomal bupivacaine Trans Quadratus Lumborum (TQL) block after the induction of general anesthesia.
- Conditions
- Pain, Postoperative, Analgesics, Opioid, Analgesics, Non-Narcotic, Physiological Effects of Drugs
- Trial name
- NCT03294109
- Testing
- Abdominal wall block with liposomal bupivicaine
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Suprazygomatic Maxillary Nerve Block
Ultrasound-Guided Suprazygomatic Maxillary Nerve Block as A Part of Multimodal Analgesic Regimens
Inadequate peri-operative analgesia may contribute to an increased risk of bleeding, suture dehiscence and unacceptable surgical outcomes.
- Trial name
- NCT05023239
- Testing
- UG-SZM Group
- Volunteers
- 52 people
- Sponsor
- Cairo University
Retrograde Intrarenal Surgery
The Effects Of Music In Retrograde Intrarenal Surgery
This study aimed to investigate the effect of music listening during the preoperative and postoperative stages in patients undergoing retrograde intrarenal surgery(RIRS) on basic life findings, anxiety, pain, and the amount of…
- Trial name
- NCT04500054
- Testing
- Music Listening
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Post-endodontic Pain
Comparison Of The Effect Of Final Rinse Of Tramadol and Dexamethasone on Post-Endodontic Pain in Teeth With SIP
Briefly, 105 teeth with symptomatic irreversible pulpitis will be included in the study and randomly allocated to three groups (A, B and C).
- Trial name
- NCT07036237
- Testing
- Tramadol group, Dexamethasone Group
- Where
- Pakistan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Opioid Use, Unspecified
Effect of Opioid Shortage on Drug Selection
This study will look at the effects of fentanyl shortage in laparoscopic cholecystectomy cases. The opioid shortage, specifically hydromorphone and fentanyl, caused a decrease in administration of opioid analgesia for…
- Trial name
- NCT04099030
- Where
- United States
- Volunteers
- 1,668 people
- Sponsor
- Wake Forest University Health Sciences
Pain
Visualisation of the Central Analgesic Effect of Paracetamol in Functional MRI
Paracetamol is one of the most widely used analgesic in the world, indicated for the symptomatic treatment of fever and pain. The objective of this study is to evaluate the mechanism of action of paracetamol (versus placebo) in…
- Trial name
- IRMf (NCT01562704)
- Testing
- Paracetamol (drug)
- Where
- France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Pain, Acute
Analgesic Effects of Cannabidiol for Simple Tooth Extractions in Dental Patients
The purpose of this study is to evaluate the analgesic effects of cannabidiol for patients who have undergone simple tooth extraction.
- Trial name
- SWAP (NCT04271917)
- Testing
- cannabidiol, acetaminophen 500mg and ibuprofen 200mg combo
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Tennessee
Knee Arthroplasty, Total, Postoperative Pain
Effect of Magnesium Sulphate on Analgesia Following Knee Arthroplasty
This study is designed to investigate the effect of magnesium sulfate added to levobupivacaine in continuous femoral nerve block following total knee arthroplasty.
- Trial name
- NCT03695640
- Testing
- Magnesium Sulfate, continuous femoral nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ufuk University
Pain, Breast Feeding
Non-pharmacological Analgesic Effects on Term Newborns
The purpose of this study is to compare the analgesic effects of four non-pharmacological interventions: skin-to-skin contact, breastfeeding, oral sucrose and nonnutritive sucking in newborns receiving a heel lance procedure.
- Trial name
- NCT03421158
- Testing
- breastfeeding, oral sucrose, Skin-to-Skin contact
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Stanford University
Inguinal Hernia
Effects of Morphine Added to Bupivacaine in Transversus Abdominis Plane Block for Inguinal Hernia Repair
This study is conducted to determine whether morphine added to bupivacaine in ultrasound guided (USG) transversus abdominis plane (TAP) block has beneficial effects than bupivacaine alone in providing postoperative analgesia for…
- Trial name
- NCT05379374
- Testing
- bupivacaine and morphine
- Where
- Nepal
- Volunteers
- 40 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Anesthesia
Comparison of Analgesic Effect of Volatile Anesthetics
The purpose of this clinical trial is to compare analgesic effect of sevoflurane and desflurane at equal minimum alveolar concentrations using surgical pleth index.
- Trial name
- NCT02830243
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Kangbuk Samsung Hospital
Gynecologic Laparoscopic Surgery, Postoperative Pain
"Efficacy of Local Anesthetic for Postoperative Pain in Gynecologic Laparoscopy"
This is a randomized, double-blind, controlled clinical trial evaluating the efficacy of local anesthetic (LA) in reducing postoperative pain in patients undergoing gynecologic laparoscopic surgery.
- Conditions
- Gynecologic Laparoscopic Surgery, Postoperative Pain, Recovery Outcomes, Pain Management
- Trial name
- NCT07030647
- Testing
- Bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Usama Ahmed Elsaeed Salem, MD
Anesthesia, Local
Analgesic Effect of Illiohypogastic & Ilioinguinal Nerve Block in TAVR - TF (Prospective Randomized Study)
The purpose of the study is to compare the effect of illiohypogastric and ilioinguinal nerve block with the local infiltration with lidocaine in patients undergoing TAVI
- Trial name
- NCT06362915
- Testing
- Lidocaine, Bupivacain
- Where
- 2 sites in Egypt
- Volunteers
- 52 people
- Sponsor
- Ain Shams University
Obesity
Erector Spina Plane Block in Laparoscopic Sleeve Gastrectomy Surgery
The aim of the study is to evaluate the effect of erector spina plane (ESP) block on pulmonary functions and postoperative analgesic consumption in patients undergoing bariatric surgery.
- Trial name
- NCT04039321
- Testing
- ESPB group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Antalya Training and Research Hospital
Sacral Erector Spinae, Penile And Caudal Block For Pain Relief After Hypospadius Surgery
Sacral Erector Spinae,Penile and Caudal Block for Pain Relief After Hypospadias Surgery
Caudal anaesthesia is recommended for most surgical procedures of the lower part of the body, mainly below the umbilicus, including inguinal hernia repair, urinary and digestive tract surgery and orthopaedic procedures on the…
- Trial name
- NCT05307653
- Testing
- Penile block, Erector spinea plain block, Caudal block
- Where
- Egypt
- Volunteers
- 132 people
- Sponsor
- Tanta University
SCS
Multicenter Outcome Registry of AnaLgesic Effect of SCS(MORALES) Registry Protocol
The objective is to provide information to help the physician community decide the most effective type of device/therapy that would work for their patients, based off of the etiology of pain, the location of the pain for…
- Trial name
- NCT04548375
- Testing
- SCS
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Cardio Surgical Partners
Hysterosalpingography, Anxiety
The Effect of Using Music and Natural Landscape Paintings on Pain Level, Anxiety and Analgesic Use of Women During HSG
The study was planned as a randomized controlled study in order to evaluate the use of music and natural scenery paintings in women who underwent HSG procedure, their pain level, anxiety and post-procedure analgesic use.
- Conditions
- Hysterosalpingography, Anxiety, Pain
- Trial name
- NCT05712954
- Testing
- music group, video group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ŞERİVAN KARAKUT
Postoperative Pain
Efficacy of Erector Spinae Plane Block in Caridac Surgery
Introduction: Opioid-based pharmacological treatment is frequently used in the treatment of pain after coronary artery bypass graft (CABG) surgery.
- Trial name
- NCT05312957
- Testing
- erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Pulpitis - Irreversible
Analgesic Effect of Low Intensity Laser in Patients With Pulpitis of Mandibular Molars.
The present study has the objective of evaluating whether the previous therapy with low intensity laser, through its analgesic effect, can promote a greater comfort specifically for patient with pulpitis in mandibular molars.
- Trial name
- NCT03553407
- Testing
- Low Level Laser - Pulse, Low Level Laser - continuous
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
HIV Infections, Peripheral Nervous System Diseases
Study of NGX-4010 for Treatment of Painful HIV-Associated Neuropathy
The purpose of the study is to determine if an investigational drug, NGX-4010 (high-concentration capsaicin patch), is safe, tolerable and effective in treating painful HIV-associated neuropathy.
- Conditions
- HIV Infections, Peripheral Nervous System Diseases, Pain
- Trial name
- NCT00085761
- Testing
- Capsaicin Dermal Patch
- Where
- 2 sites in United States
- Sponsor
- NeurogesX