Clinical trials: Anastomosis, Surgical
Pancreatic Fistula
Total pancrEaTectomy vs High-Risk Pancreatic anastomosiS
Postoperative pancreatic fistula (POPF) is the main driver of surgical morbidity after pancreatoduodenectomy (PD). The aim of the present study is to compare total pancretectomy (TP) and primary pancreatic anastomosis (PA) in a…
- Trial name
- TETRIS (NCT05212350)
- Testing
- Total pancreatectomy, Pancreatic anastomosis
- Where
- 5 sites in Germany, Italy
- Volunteers
- 98 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Education, Medical
Evaluation of Surgical Simulator for Practicing a Vascular Anastomosis
To determine if practicing an aorto-saphenous vein anastomosis on a low-fidelity surgical simulator allows trainees to produce a higher quality anastomosis in a shorter period of time, than a group that only learns by watching a…
- Trial name
- NCT00318279
- Testing
- Surgical simulator to practice vascular anastomosis
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Anastomotic Leak Rectum, Rectal Cancer
Healing of Rectal Anastomosis Sealed With a Concentrate Derived From the Patient's Blood, After Rectal Cancer Surgery
Rectal cancer is one of the most frequent cancer diseases, with more than 1500 new cases per year in Denmark. Fortunately, if the tumor is discovered early, surgeons can remove the part of the intestine that is afflicted, and…
- Conditions
- Anastomotic Leak Rectum, Rectal Cancer, Anastomotic Leakage
- Trial name
- OBANORES (NCT05293054)
- Testing
- Application of autologous fibrin matrix (Obsidian)
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Anastomosis, Surgical
Evaluation of MUSA-3 in Microsurgical Anastomoses
This study is conducted to evaluate the safety and performance of robot-assisted microsurgical anastomoses with the MUSA-3 system.
- Trial name
- NCT07427823
- Testing
- Robot-assisted microsurgical anastomoses
- Volunteers
- 30 people
- Sponsor
- Microsure
Ulcerative Colitis, Surgery
Energy Expenditure in Patients With Ulcerative Colitis Undergoing Surgery
A prospective observational study to assess the energy needs of Ulcerative Colitis patients undergoing total proctocolectomy with ileoanal j-pouch anastomosis.
- Trial name
- NCT06221995
- Testing
- Indirect Calorimetry
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- Evangelismos Hospital
Peritonitis
Role of Protective Stoma After Primary Anastomosis for Generalized Peritonitis Due to Perforated Diverticulitis
This study is designed to be a multicentre, prospective, comparative, randomised trial, evaluating the efficacy of two surgical strategies for the treatment of generalised peritonitis due to perforated diverticulitis.
- Trial name
- DIVERTI2 (NCT04604730)
- Testing
- Primary anastomosis without protective stoma, Anastomosis with protective stoma
- Where
- 20 sites in France
- Volunteers
- 204 people
- Sponsor
- University Hospital, Rouen
Crohn's Disease of Large Intestine, Malignant Neoplasm of Colon
Evaluation of Ability to Detect Bowel Gas During Laparoscopic Right Colectomy With Intracorporeal Anastomosis
Undetected bowel perforation is a rare but dangerous complication of laparoscopic surgery. If the injury is not detected and treated at the time of the surgical procedure, the patient can suffer severe complications, including…
- Trial name
- NCT04964297
- Testing
- Obtaining bowel gas samples
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Weill Medical College of Cornell University
Unnecessary Nasogastric Tube, Bowel Anastomosis
Unnecessary Gastric Decompression in Distal Elective Bowel Anastomoses in Children. A Randomized Study
Objective. To study the role of nasogastric drainage to prevent postoperative complications in children with <b>distal</b> elective bowel anastomosis. Summary Background Data.
- Trial name
- NCT01011023
- Testing
- Non application of nasogastric tube in the experimental group
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Alzheimer Disease
Study Safety and Efficacy of Deep Brain Stimulation (DBS) and Cervical Deep Lymphoid-venous Anastomosis (LVA) in Alzheimer's Disease
To investigate the safety of deep brain stimulation (DBS) and cervical deep lymphoid-venous anastomosis (LVA) in the treatment of severe Alzheimer's disease (AD); to investigate the effectiveness of DBS and LVA in the treatment…
- Trial name
- NCT07094438
- Testing
- Deep Brain Stimulation, DBS, Deep cervical lymphatic-venous anastomosis, LVA, Recognized pharmacological treatments for AD.
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Chinese PLA General Hospital
Obesity, Obesity Type 2 Diabetes Mellitus
Prospective Evaluation of Stapled Intact-Duodenum Bipartition With Sleeve Gastrectomy (SIBS)
Obesity is a chronic disease that can be treated with metabolic and bariatric surgery when appropriate. This study will prospectively evaluate a new laparoscopic bariatric procedure called Stapled Intact-Duodenum Bipartition with…
- Trial name
- SIBS (NCT07765758)
- Testing
- Stapled Intact-Duodenum Bipartition With Sleeve Gastrectomy (SIBS)
- Where
- Oman
- Volunteers
- 50 people
- Sponsor
- Medical City for Military and Security Services
Lymphedema, Lymphedema Arm
The Robot-LVA Study: Robot-assisted Microsurgical Lymphaticovenous Anastomosis in Breast Cancer-related Lymphedema
This study assesses the performance of robot-assisted microsurgery. Lymphaticovenous anastomosis (LVA) is the most difficult procedure in microsurgery at this moment.
- Conditions
- Lymphedema, Lymphedema Arm, Lymphedema of Upper Arm, Lymphedema of Upper Limb
- Trial name
- NCT06532955
- Testing
- Lymphaticovenous anastomosis using Microsure Motion Stabilizer, Lymphaticovenous anastomosis (manual)
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht University Medical Center
Esophageal Stricture, Duodenal Stricture
Cryoablation for Benign Gastrointestinal Anastomotic Strictures
Anastomotic stricture is a common complication following foregut surgery. The standard of care for these benign foregut anastomotic strictures is balloon dilatation.
- Conditions
- Esophageal Stricture, Duodenal Stricture, Jejunal Stricture, Anastomotic Stricture of Small Intestine
- Trial name
- NCT04372784
- Testing
- Cryotherapy, Esophagogastroduodenoscopy with Balloon Dilatation
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- University of Southern California
Right Colon Cancer
Mechanical Resistance Curves of the NTLC75 Linear Stapler During Barcelona Ileotransverse Anastomosis
This prospective single-center pilot cohort will include 40 consecutive adults undergoing elective right colectomy with a Barcelona ileotransverse anastomosis using an NTLC75/SR75 linear stapler.
- Trial name
- NTLC75-ITA (NCT07834385)
- Testing
- Passive External NTLC75 Handle-Signal Recording
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- University Hospital of Split
Crohn Disease (CD), Crohn Disease of Ileum
Laparoscopic Right Hemicolectomy for Crohn's Disease of the Terminal Ileum Utilizing the Mesenteric Excision and Exclusion
This study is designed for patients requiring surgery for Crohn's disease of the terminal ileum. A combination of laparoscopic segmental right colectomy with extended mesenteric excision and the Kono-s anastomosis will be…
- Conditions
- Crohn Disease (CD), Crohn Disease of Ileum, Kono S Anastomosis, Extended Mesenteric Excision
- Trial name
- NCT07231601
- Testing
- Mesenteric excision and exclusion
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tzaneio General Hospital
Prokinetic Use After Emergency Intestinal Anastomosis
Impact of Prokinetic Use After Emergency Intestinal Anastomosis on Postoperative Clinical Outcomes
Prokinetic drugs used to accelerate healing of intestinal anastomosis of urgent cases which not prepared preoperative by increase intestinal motility and gastric emptying and decrease postoperative adhesions They are many types…
- Trial name
- NCT05290753
- Testing
- Prokinetic Motility Agents as primpiram and gastreg
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Sohag University
Coronary Arteriosclerosis
Epicardial Echocardiography of Coronary Anastomoses Using the Echoclip Device
The aim of this study is to evaluate whether use of the echoclip device (an ultrasound transducer positioning device which can stabilize the involved part of the myocardium on the beating heart) facilitates imaging of coronary…
- Trial name
- NCT02919124
- Testing
- Echoclip
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- Aalborg University Hospital
Anastomotic Leakage
Drainage Fluid Biomarkers and Anastomotic Leakage in Colorectal Surgery. A Monocentric Prospective Observational Study
Anastomotic leakage (AL) is one of the most feared intra-abdominal septic complications (IASC) after colorectal surgery. It is defined as the leak of intestinal content due to an anastomotic dehiscence.
- Trial name
- ALbiomarkers (NCT04846283)
- Testing
- Elective or emergency colorectal surgery for cancer, diverticular disease, inflammatory bowel-disease or reversal of Hartmann's procedure
- Where
- Italy
- Volunteers
- 207 people
- Sponsor
- University of Palermo
Alzheimer, Alzheimer Dementia (AD)
Restoring Cervical Lymphatic Drainage in Alzheimer's Disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with the accumulation of abnormal proteins, including amyloid-beta and tau, in the brain.
- Trial name
- LymphDAD (NCT07854327)
- Testing
- Cervical lymphovenous anastomosis (LVA)
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- University of Siena
Urethral Stricture, Surgery
VeSpAR: Comparing Vessel-Sparing Anastomotic Repair and Transecting Anastomotic Repair in Isolated Short Bulbar Strictures.
The investigators want to verify whether the surgical outcome of vessel-sparing anastomotic repair in isolated short bulbar urethral strictures is not inferior to the surgical outcome of transecting anastomotic repair.
- Conditions
- Urethral Stricture, Surgery, Urologic Diseases
- Trial name
- VeSpAR (NCT03572348)
- Testing
- Transecting anastomotic repair (tAR), Vessel-sparing anastomotic repair (vsAR)
- Where
- 13 sites in United States, Argentina and 6 more
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Anastomosis, Leaking, Anastomotic Stenosis
Outcomes Of Single-Layer Extramucosal Colostomy Closure With Full-Thickness (All-Layers) Colostomy Closure
to compare the clinical outcomes of single-layer extramucosal colostomy closure with full-thickness (all-layers) colostomy closure in paediatric patients.
- Trial name
- NCT07411885
- Testing
- extramucasal colostomy closure, full thickness closure
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Children Hospital and Institute of Child Health, Lahore