Clinical trials: Anastomosis; Complications
Cancer
Peritoneal Microdialysis in Patients Undergoing Low Anterior Resection for Rectum Cancer
Anastomotic leakage is a serious complication after LAR with high morbidity and mortality rates. Early diagnosis and treatment is mandatory.
- Trial name
- NCT01062334
- Testing
- Peritoneal Microdialysis, CT-scan, leakage scoring
- Where
- 2 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Odense University Hospital
Postoperative, Anastomosis, Surgical
Closure of Anastomotic Leaks in the Stomach and Esophagus by Endoscopic Suturing
Patients with suspected leakage at the specified surgical anastomoses undergo an immediate diagnostic endoscopy as part of current clinical routine.
- Trial name
- GASTROSUTURE (NCT01139424)
- Testing
- endoscopic suturing
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Schleswig-Holstein
Genito Urinary Function Evaluation
Genito Urinary Function With High or Low Inferior Mesenteric Artery Ligation in Laparoscopic Anterior Rectal Resection
The aim of this study is to compare the incidence of genito-urinary function depression and anastomotic leak in Laparoscopic Anterior Rectal Resection (LAR) with Total Mesorectal Excision with Ligation if the Inferior Mesenteric…
- Trial name
- NCT02153801
- Testing
- During the surgical procedure of Laparoscopic Low Anterior Resection with Total mesorectal Excision .
- Where
- Italy
- Volunteers
- 212 people
- Sponsor
- Niguarda Hospital
Enteral Feeding, Neonate
Safety and Effectiveness of Early Feeding After Bowel Anastomosis in Neonates or Infants
The study is primary designed to evaluate the safety and effectiveness of early feeding after bowel anastomosis, and observe the effect of early postoperative feeding on promoting postoperative rehabilitation and reducing…
- Conditions
- Enteral Feeding, Neonate, Infant, Intestinal Anastomosis Complication
- Trial name
- NCT04464057
- Testing
- early oral feeding or early enteral nurtrion
- Where
- 2 sites in China
- Volunteers
- 947 people
- Sponsor
- Weibing Tang
Anastomotic Leak
Use of NERv's Inline Device as an Early Diagnostic Method for Anastomotic Leak.
NERv's early feasibility clinical trial is a first-in-human, multi-center, pre-market, non-randomized clinical trial intended to evaluate the safety and collect preliminary data necessary for the detection of clinical…
- Trial name
- NCT04253028
- Testing
- NERv's Inline Device
- Where
- 2 sites in Egypt
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- FluidAI Medical
Anastomotic Leak
Predictors of Intestinal Anastomosis Leakage, Application of New Predictors and New Scores
Aim of the work This study aims at; Early detection of disruption and leakage of intestinal anastomotic sites whether small or large intestine by using biochemical markers as predictors and indicators of leakage with application…
- Trial name
- NCT04422106
- Testing
- Predictors of intestinal anastomosis leakage, application of new predictors and new scores
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Mansoura University
Liver Transplant
Stented Biliary Anastomosis in Living Donor Liver Transplantation
Determination of biliary complications in stented group compared to duct to duct anastomosis without stent
- Trial name
- NCT03636321
- Testing
- living donor liver transplantation with internal biliary stent
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alaa Mstafa Hassan Sewefy
Anastomotic Leak
Risk Factors Associated With Anastomotic Leak and Perioperative Mortality in Elderly
This is a retrospective cohort study of all consecutive patients who underwent colon or rectal resection, between the years 2012-2017 at Rabin Medical Center, a tertiary referral center in Israel.
- Trial name
- NCT04518384
- Testing
- colon or rectum resection
- Where
- Israel
- Volunteers
- 536 people
- Sponsor
- Rabin Medical Center
Rectum Cancer, Faecal Incontinence
Exploring the Effect of Colonic J-pouch in Anorectal Preservation Surgery for Ultra-low Rectal Cancer.
The occurrence of colorectal cancer has increased from the third most common cancer in 2018 to the second most common cancer in 2023.
- Conditions
- Rectum Cancer, Faecal Incontinence, Faecal Incontinence with Faecal Urgency, Low Anterior Resection Syndrome
- Trial name
- NCT06601985
- Testing
- J-pouch anastomosis, direct anastomosis
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Shanghai 10th People's Hospital
Liver Transplant; Complications, Biliary Duct Obstruction
Clinical Usefulness of Digital Single-operator Cholangioscopy(SpyGlass™) for Post-liver Transplant Anastomotic Stricture
Liver transplantation (LT) is an essential treatment for end-stage liver disease. Although clinical outcomes of LT recipients have markedly improved, anastomotic biliary strictures (ABS) are still occurred in 10-40% of post-LT…
- Conditions
- Liver Transplant; Complications, Biliary Duct Obstruction, Anastomosis, Obstructed
- Trial name
- NCT05065125
- Testing
- digital single-operator cholangioscopy
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Surgical Site Infection, Anastomotic Leak
Oral Antibiotic Prophylaxis in Colorectal Surgery
The investigators perform a case-control study to compare preparation before elective colorectal surgery. The first group is a prospective patient - registry in all patients with mechanical bowel preparation (MBP) and oral…
- Trial name
- ABCR (NCT03759886)
- Testing
- Paromomycin Sulfate Powder
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Leipzig
Anastomotic Leak, Anastomotic Leak Large Intestine
Low Tie Versus High Tie of the Inferior Mesenteric Vein During Colorectal Cancer Surgery: A Randomized Clinical Trial
This study aim to determine if a different surgical technique could result in a lower anastomotic leak rate. The two techniques are equally used around the world and well described by the international literature but this is the…
- Conditions
- Anastomotic Leak, Anastomotic Leak Large Intestine, Anastomotic Leak Rectum, Colon Cancer
- Trial name
- LOTHVEIN (NCT05411783)
- Testing
- Low tie of IMV
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- San Carlo di Nancy Hospital
Anastomotic Leak, Gastric Cancer
Anastomotic Leak Testing in Gastrectomy
Anastomotic leak after radical gastrectomy is a serious complication. Intraoperative leak testing was often used to assess the integrity of the anastomosis.
- Conditions
- Anastomotic Leak, Gastric Cancer, Surgery, Testing, Reality
- Trial name
- NCT04292496
- Testing
- Introperative leak testing
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Nanchong Central Hospital
Anastomotic Leak, Microbial Colonization
SURGIcal COmplication and MIcrobiome ChangeS in Colorectal Surgery
The microbiome, the collection of microorganisms that live in our gut, plays an important role in maintaining our health, proper nutrient absorption, nutrient turnover and immunity.
- Trial name
- Surgi-Comics (NCT05779254)
- Testing
- Neomycin Sulfate
- Where
- 3 sites in Hungary
- Volunteers
- 100 people
- Sponsor
- Uzsoki Hospital
Gastric Cancer
Validation of a Model for Predicting Anastomotic Leakage
This study will validate a machine learning model for predicting anastomotic leakage of esophagogastrostomy and esophagojejunostomy.
- Trial name
- NCT05646290
- Where
- China
- Volunteers
- 512 people
- Sponsor
- Jichao Qin
Esophageal Malignant Neoplasm Primary, Anastomotic Leak
Registry Study of People Who Are Having an Esophagectomy and Are at High Risk of Anastomotic Leak
The main purpose of this study is to look at how often anastomotic leaks happen in participants who are at high risk of these leaks and are eligible to receive gastric preconditioning by percutaneous angioembolization before an…
- Trial name
- NCT07449208
- Testing
- Esophagectomy
- Where
- 7 sites in United States
- Volunteers
- 40 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Rectal Cancer Patients, Rectal Cancer Surgery
FLuorescent Angiography in REduction of Anastomotic Leak in Rectal Cancer Surgery
The goal of this clinical trial is to find out whether using a special green dye called indocyanine green (ICG) during minimally invasive rectal cancer surgery can help surgeons assess blood flow to the bowel and reduce leakage…
- Conditions
- Rectal Cancer Patients, Rectal Cancer Surgery, Colorectal Cancer, Anastomotic Leak Rectum
- Trial name
- FLARE (NCT07899125)
- Testing
- Indocyanine Green Fluorescence Angiography, Standard Surgical Perfusion Assessment
- Where
- India
- Volunteers
- 610 people
- Sponsor
- Basavatarakam Indo American Cancer Hospital & Research Institute
Stoma Ileostomy, Stoma Colostomy
Conventional Hand Sewn End-To-End Anastomosis Versus Side-To-Side Anastomosis for Stoma Reversal: A Prospective Study
The goal of this clinical trial is to compare approaches to enterostomy reversal by hand-sewn end-to-end anastomosis versus side-to-side anastomosis (sub-divided into hand-sewn side-to-side anastomosis and stapled side-to-side…
- Conditions
- Stoma Ileostomy, Stoma Colostomy, Anastomosis, Ileus
- Trial name
- NCT05753709
- Testing
- Hand sewn end-to-end anastomosis, Hand sewn side-to-side anastomosis, Stapled side-to-side anastomosis
- Where
- India
- Volunteers
- 38 people
- Sponsor
- Sawai Mansingh Medical College
Anastomotic Leak, Sigmoid Diseases
Lateral Invagination of the Colorectal Anastomosis by Double Stapling
Anastomotic dehiscence is the most feared complication in colorectal surgery, occurring in 6.3% -13.7% in patients with pelvic anastomoses [1-4].
- Trial name
- NCT04553250
- Testing
- Doubled-stapled colorectal anastomosis
- Volunteers
- 786 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Periampullary Carcinoma, Pancreatic Fistula
Trial of Omental Roll-up Technique on Pancreato-jejunostomy Anastomosis for Reducing Perioperative Complication in Patients Undergoing Pancreatoduodenectomy
Despite the fact that pancreatoduodenectomy is the standard treatment of malignant tumor at periampullary area, the morbidity and mortality rate with intra-abdominal collection, post pancreatectomy hemorrhage, and delayed gastric…
- Trial name
- NCT03083938
- Testing
- Omental Roll-up
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University