Clinical trials: Anastomotic Leak Large Intestine
Anastomotic Leak, Anastomotic Leak Large Intestine
A1Check: the External Validation of a Machine Learning Model Predicting Colorectal Anastomotic Leakage
Anastomotic leakage is a severe complication that can arise following a colorectal resection. It impairs both the short- and long-term outcomes, and negatively influences cancer recurrence rates.
- Conditions
- Anastomotic Leak, Anastomotic Leak Large Intestine, Anastomotic Complication, Anastomotic Leak Rectum
- Trial name
- A1Check (NCT05810207)
- Testing
- Colorectal resection
- Where
- 8 sites in Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Freek Daams
Anastomosis; Complications, Anastomosis, Surgical
Role of Indexed Oxygen Delivery in Anastomotic Insufficiencies in Elective Laparoscopic Colorectal Resections for Cancer
Colorectal cancer is a very commonly diagnosed malignancy worldwide, and surgical resection remains the mainstay of treatment. Outcomes depend on preoperative staging, surgical quality, complication rates, and multidisciplinary…
- Conditions
- Anastomosis; Complications, Anastomosis, Surgical, Anastomosis, Leaking, Anastomotic Leaks
- Trial name
- NCT07099820
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Saint Camillus International University of Health Sciences
Anastomotic Leak Rectum, Anastomotic Leak Large Intestine
Endoscopic COlorectal Mucosal Evaluation of Oxygen Tension
Anastomosis refers to the surgical connection between two segments of the bowel, typically performed during colon and rectal surgeries to restore the continuity of the digestive tract after a section has been removed.
- Trial name
- e-COMET (NCT07467980)
- Testing
- A novel endoscopic imaging system that displays real-time oxygen saturation levels
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Vanderbilt University Medical Center
Anastomotic Leak Small Intestine, Anastomotic Leak Large Intestine
Enhanced Perioperative Care for the Prevention of Colorectal Anastomotic Leakage
This multicenter open-label trial is designed to evaluate if the implementation of an enhanced peri-operative care protocol results in an optimal intraoperative condition of the patient and in a decrease in incidence of…
- Conditions
- Anastomotic Leak Small Intestine, Anastomotic Leak Large Intestine, Anastomotic Leak Rectum, Intraoperative Awareness
- Trial name
- DOUBLE CHECK (NCT05250882)
- Testing
- Enhanced perioperative care protocol
- Where
- 9 sites in Belgium, Netherlands
- Volunteers
- 1,600 people
- Sponsor
- Amsterdam UMC, location VUmc
Intestinal Anastomotic Leak
Risk Factors for Anatomic Leakage in Advanced Ovarian Cancer Surgery
Cytoreductive surgery is currently the main treatment for advanced epithelial ovarian cancer (AEOC), and the complete disease removal (RT=0) or the achievement of an optimal residual disease (RT < 1 cm) remain the factors with…
- Trial name
- NCT04604964
- Testing
- Evaluation of anastomotic leakage occurrence
- Where
- Italy
- Volunteers
- 515 people
- Sponsor
- Catholic University of the Sacred Heart
Anastomotic Leak, Anastomotic Leak Large Intestine
Low Tie Versus High Tie of the Inferior Mesenteric Vein During Colorectal Cancer Surgery: A Randomized Clinical Trial
This study aim to determine if a different surgical technique could result in a lower anastomotic leak rate. The two techniques are equally used around the world and well described by the international literature but this is the…
- Conditions
- Anastomotic Leak, Anastomotic Leak Large Intestine, Anastomotic Leak Rectum, Colon Cancer
- Trial name
- LOTHVEIN (NCT05411783)
- Testing
- Low tie of IMV
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- San Carlo di Nancy Hospital
Anastomotic Complication, Anastomotic Leak Small Intestine
Open Abdomen and Delayed Anastomosis After Anastomotic Dehiscences to Avoid Stomas
Phase III clinical trial to evaluate the efficacy of the open abdomen as bridging therapy to perform transit reconstruction in patients with anastomotic dehiscence.
- Conditions
- Anastomotic Complication, Anastomotic Leak Small Intestine, Anastomotic Leak Large Intestine
- Trial name
- STOP-STOMA (NCT05233995)
- Testing
- Damage Control Surgery
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Colo-rectal Surgery, Anastomotic Leak Large Intestine
Comparison of Rates of Anastomotic Leak in Patients Undergoing Colo-rectal Surgery When Bowel Perfusion and Resection Margin is Deterimined by Intra-operative Infra-red Thermography or by Conventional Method
Pilot RCT with 20 patients in both test and control group. In the control group resection \& anastomosis was done using the conventional method.
- Conditions
- Colo-rectal Surgery, Anastomotic Leak Large Intestine, Anastomotic Leak Rectum
- Trial name
- NCT06180564
- Testing
- Intra-operative Infra-red thermography
- Where
- India
- Volunteers
- 43 people
- Sponsor
- Sir Ganga Ram Hospital
Anastomotic Leak Large Intestine, Right Colon Tumors
Anastomotic Leakage After Right Hemicolectomy for Cancer, a Prospective Multicenter Study of SICO-CC Network
This is a nationwide prospective observational study to assess the overall clinical anastomotic leakage rate after right hemicolectomy for cancer, to detect the independent risk factors for AL, and to develop a clinical…
- Trial name
- ALRIGHT (NCT06688383)
- Where
- Italy
- Volunteers
- 1,839 people
- Sponsor
- San Luigi Gonzaga Hospital
Anastomotic Leakage in Colon Surgery, Anastomotic Leak Rectum
Anastomotic Leakage in Colorectal Cancer Surgery in Syria
Anastomotic leakage is a serious complication of colorectal cancer surgery, particularly in resource-limited and conflict-affected settings.
- Conditions
- Anastomotic Leakage in Colon Surgery, Anastomotic Leak Rectum, Anastomotic Leak Large Intestine
- Trial name
- NCT07092631
- Where
- Syria
- Volunteers
- 119 people
- Sponsor
- Elie Bitar
Anastomotic Leak Large Intestine, Anastomotic Leak Rectum
"Colorectal Leakage App" for Early Detection of Anastomotic Leakage After Colorectal Surgeries
The aim of this prospective observational study is to evaluate the effectiveness of the mobile application "Colorectal Leakage App" in the early diagnosis of anastomotic leakage after colorectal surgeries at the National Research…
- Trial name
- NCT06273826
- Testing
- "Colorectal Leakage App"
- Where
- Kazakhstan
- Volunteers
- 120 people
- Sponsor
- National Research Oncology and Transplantology Center, Kazakhstan