Clinical trials: Anemia, Iron-deficiency
Iron Deficiency Anemia
A Trial Comparing Ferumoxytol With Iron Sucrose for the Treatment of Iron Deficiency Anemia
The purpose of the study is to evaluate the efficacy and safety of intravenous (IV) ferumoxytol compared to IV iron sucrose for the treatment of iron deficiency anemia (IDA).
- Trial name
- NCT01114204
- Testing
- Ferumoxytol, Iron Sucrose
- Where
- 96 sites in Australia, France and 12 more
- Volunteers
- 605 people
- Sponsor
- AMAG Pharmaceuticals, Inc.
Anemia, Intrauterine Growth Retardation
Impact of Pre-pregnancy Micronutrient Supplementation on Maternal and Child Outcomes
The study evaluates the efficacy of providing weekly iron-folate (IFA) supplements or Multiple Micronutrient (MM) supplements before pregnancy in increasing birth weight and duration of gestation as well as maternal and infant…
- Conditions
- Anemia, Intrauterine Growth Retardation, Preterm Delivery, Iron Deficiency
- Trial name
- NCT01665378
- Testing
- Multiple Micronutrient, Iron and Folic Acid, Folic Acid
- Where
- Vietnam
- Volunteers
- 5,011 people, healthy volunteers welcome
- Sponsor
- Emory University
Iron-deficiency Anemia
Iron Fortified Beverages and Application in Women Predisposed to Anemia
The objective of the study is to know if consumption of an iron fortified fruit juice containing micronized iron pyrophosphate, is useful to increase iron status in women predisposed to iron deficiency anemia.
- Trial name
- FeDrink (NCT01135576)
- Testing
- non-fortified fruit juices consumed as part of the usual diet, Iron fortified fruit juice
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Anemia
A Functional Food for the Prevention of Iron-deficiency Anemia
It has been estimated that 1 in 2 women expecting a baby will be diagnosed with iron deficiency. In turn iron deficiency can affect the health and wellbeing or both mother and child.
- Trial name
- NCT01055431
- Testing
- Control bread, Teff Bread
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Manchester Metropolitan University
Iron Deficiency Anemia
A Trial of Ferumoxytol for the Treatment of Iron Deficiency Anemia in Pediatric Participants With Chronic Kidney Disease
Study evaluating the efficacy and safety of intravenous (IV) ferumoxytol compared with oral iron for the treatment of pediatric participants with chronic kidney disease (CKD).
- Trial name
- NCT01155375
- Testing
- Ferumoxytol, Oral Iron
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- AMAG Pharmaceuticals, Inc.
Restless Leg Syndrome, Iron Deficiency Anemia
Restless Legs Syndrome With Iron Deficiency or Anaemia in the 3rd Trimester of Pregnancy
In pregnancy Restless Legs Syndrome(RLS) is more common than in the general population. During pregnancy iron tablets are the only available safe medication but their efficacy is rather poor.
- Trial name
- NCT01245777
- Testing
- ferric carboxymaltose
- Where
- 2 sites in Switzerland
- Volunteers
- 15 people
- Sponsor
- University of Zurich
Tourette Syndrome
The Pathophysiology of Tourette Syndrome: a Multimodal Study
The purpose of this study is to characterize the functional and anatomical connectivity changes in Tourette syndrome and its relation with iron deficiency.
- Trial name
- PTS (NCT02497807)
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Iron-deficiency, Iron Deficiency Anemia
IP Peru, Bioavailability of Iron From Potatoes
To combat iron deficiency in Low and Middle-Income Countries, sustainable food-based solutions have to be implemented to serve populations, not only individuals.
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Iron Deficiency (Without Anemia)
- Trial name
- IPPERU (NCT04216030)
- Testing
- High Fe IP meal labelled with Fe-58, Control OFSP meal labelled with Fe-57
- Where
- Peru
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency Anemia
Iron Fortified Food to Improve Japanese Encephalitis and Typhoid Fever Vaccine Immunogenicity
Iron deficiency (ID) anaemia (IDA) is a global public health problem, with the highest prevalence in Africa and in South-East Asia.
- Trial name
- NCT06027801
- Testing
- Iron-fortified cookies, Japanese encephalitis (JE) vaccine, Typhoid Vi polysaccharide (Vi-PS) vaccine
- Where
- Thailand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Iron Deficiency
Effect of Vitamin C on Iron Absorption
Iron deficiency is a common health problem worldwide. Ferrous fumarate (a form of iron) is often added to foods in an effort to prevent iron deficiency.
- Trial name
- NCT00570895
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Cerebral Palsy, Iron Deficiency Anemia
Comparison of Twice Weekly Versus Daily Iron Therapy in Treating Anemia in Children With Cerebral Palsy
a randomized clinical trial to compare the effect of twice weekly versus daily iron therapy in treating anemia in children with cerebral palsy, to be conducted at Department of pediatric medicine children's hospital PIMS…
- Trial name
- NCT06176430
- Testing
- Ferrous Sulfate Oral Product
- Volunteers
- 160 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Iron Deficiency Anemia, Neurodevelopmental Abnormality
RAPIDIRON Trial Follow-up Study: RAPIDIRON-KIDS Study
As a follow-up to the RAPIDIRON Trial (NCT05358509), this study will follow the previously randomized mothers as well as their offspring after birth to assess neurodevelopmental, hematologic, and health outcomes.
- Conditions
- Iron Deficiency Anemia, Neurodevelopmental Abnormality, Autism Spectrum Disorder
- Trial name
- RAPIDIRON-KIDS (NCT05504863)
- Testing
- Ferric carboxymaltose, Iron isomaltoside, Ferric Sulfate
- Where
- 3 sites in India
- Volunteers
- 538 people
- Sponsor
- Thomas Jefferson University
Anemia, Iron Deficiency, Anemia of Chronic Disease
Hemoglobin Optimization to Prevent Transfusion and Adverse Events in Perioperative Patients With Iron Restricted Anemia
The HOPE-Hb trial is a phase II study to determine the feasibility and impact of a combination treatment (intravenous iron plus erythropoietin) versus intravenous iron treatment alone on preoperative hemoglobin concentration…
- Conditions
- Anemia, Iron Deficiency, Anemia of Chronic Disease, Hip Arthropathy, Knee Arthropathy
- Trial name
- HOPE-Hb (NCT03528564)
- Testing
- Iron sucrose, Epoetin Alfa
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- Unity Health Toronto
Hepcidin, Saliva
Assessement of Hepcidin in Saliva in Human Volunteers
Iron deficiency with or without anemia is considered the most widespread nutritional deficiency in the world. To diagnose iron deficiency anemia (hemoglobin and ferritin measurement), a venous blood sample is necessary.
- Trial name
- NCT03816813
- Testing
- blood and saliva sampling
- Where
- Switzerland
- Volunteers
- 90 people
- Sponsor
- Swiss Federal Institute of Technology
Anemia
Using Iron Supplementation to Decrease Iron Deficiency Anemia in Infants and Young Children in India
The purpose of this study is to determine the smallest dose of Sprinkles, a single-serving package of iron and other micronutrients, to treat infants with iron deficiency anemia in India.
- Trial name
- NCT00213161
- Testing
- iron supplement, iron drops
- Where
- India
- Volunteers
- 425 people
- Sponsor
- The Hospital for Sick Children
Iron Deficiency Anemia, Chronic Kidney Disease
Iron Isomaltoside 1000 (Monofer®) in Non-Dialysis Dependent Chronic Kidney Disease and With Renal-Related Anaemia
The study is designed to determine the effects of an investigational drug Monofer in subjects with non-dialysis dependent chronic kidney disease (NDD-CKD) subjects and with iron deficiency anaemia (IDA).
- Trial name
- NCT01102413
- Testing
- Monofer, Iron Sulphate
- Where
- Denmark
- Volunteers
- 351 people
- Sponsor
- Pharmacosmos A/S
Iron-deficiency
Iron Bioavailability of High Surface Area Ferric Phosphate
The primary objective of this study is to compare iron absorption of high surface area ferric phosphate with that of ferrous sulfate and bulk ferric phosphate in a rice-based meal in non-pregnant women.
- Trial name
- HiFe (NCT03660462)
- Testing
- FeSO4 fortified rice test meal, FePO4 fortified rice test meal, HiFePO4 1 fortified rice test meal
- Where
- Thailand
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Malnutrition, Stunting of Growth
Efficacy of Caterpillar Cereal for Complementary Feeding in the Democratic Republic of Congo
Two in every three infants in rural areas of the Democratic Republic of Congo (DRC) suffer from stunting of linear growth by 12 months of age.
- Conditions
- Malnutrition, Stunting of Growth, Iron Deficiency Anemia, Neurodevelopmental Impairment
- Trial name
- CAT02 (NCT01282788)
- Testing
- Caterpillar Cereal
- Where
- Republic of the Congo
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Iron-deficiency
Effect of Prebiotics on Iron Absorption in Women With Low Iron Stores
Rationale: According to the WHO, iron deficiency is still the most common and widespread nutritional disorder in the world. Current iron supplements have limitations in terms of bioavailability and tolerability.
- Trial name
- Fe_GOS_1 (NCT03325270)
- Testing
- labeled ferrous fumarate, labeled ferrous fumarate + prebiotics, labeled ferrous sulfate + prebiotics
- Where
- Switzerland
- Volunteers
- 46 people
- Sponsor
- Swiss Federal Institute of Technology
Cognitive Function and Mood, Non-anaemic Iron Deficiency
Efficacy Evaluation of 16 Weeks' Dietary Supplementation With Iron Bis-glycinate Plus Vitamin C on Cognitive Function, Subjective Mood, Fatigue, Health and Well-being
Iron deficiency is the most prevalent nutritional deficiency worldwide with one in four estimated to be affected by iron deficiency anaemia.
- Trial name
- NCT04469010
- Testing
- Iron Bis-Glycinate Chelate and Vitamin C, Iron Bis-Glycinate Chelate
- Where
- United Kingdom
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Northumbria University