Clinical trials: Anemia, Iron-deficiency
Iron Deficiency Anemia
Oral Iron Substitution for Orthopedic Surgery
The aim of this pilot study is to investigate an 4 weeks period of oral iron substitution in the course of Patient Blood Management in preparation for orthopedic surgery.
- Trial name
- NCT02973074
- Testing
- OLEOvital
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Kepler University Hospital
Iron Deficiency Anemia
Measuring Erythrocyte Iron Incorporation From Different Dosing Regimens in Anemic Women
Iron-deficient anaemic subjects are likely to benefit most from oral iron supplements, but supplementation schedules vary widely in clinical practice, absorption is low and compliance is poor due to mild gastrointestinal side…
- Trial name
- NCT03623997
- Testing
- Iron stable isotope labeled iron(II) sulfate
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Varus-Derotation Osteotomy Surgery, Iron-deficiency Anemia
Pediatric Outcomes and Recovery With Peri-Operative Iron Supplement Evaluation
Varus-derotation osteotomy (VDRO) is a surgery to prevent or address hip displacement in children. Many children having this surgery have cerebral palsy or other neuromotor disorders, who have a higher rate of malnutrition…
- Conditions
- Varus-Derotation Osteotomy Surgery, Iron-deficiency Anemia, Pelvic Osteotomy Surgery, Cerebral Palsy
- Trial name
- PORPOISE (NCT07095244)
- Testing
- Iron Supplement, Comprehensive Nutrition Management
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- University of British Columbia
Hypophosphatemia
Effects of Treatments for Anemia and Iron Deficiency on the Electrolyte Balance in Lung Transplant Recipients: A Special Focus on Hypophosphatemia
The aim of this study is to generate evidence regarding hypophosphatemia after iron infusion in lung transplant recipients in context of anemia and/or iron deficiency.
- Trial name
- NCT06112236
- Testing
- no intervention
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- University of Zurich
Heart Failure
Differential Gene Expression in Patients With Heart Failure and Iron Deficiency - Effects of Ferric Carboxymaltose
The primary efficacy objective of this study is to evaluate the effect of ferric carboxymaltose on mitochondrial gene activation pattern after 12 weeks of treatment.
- Trial name
- NCT01978028
- Testing
- ferric carboxymaltose
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich
Iron Deficiency Anaemia in Childbirth
EFFICACY OF IV VERSUS ORAL IRON IN THE TREATMENT OF IRON DEFICIENCY ANEMIA DURING PREGNANCY
This study was planned to compare outcomes of IV versus oral iron in the treatment of iron deficiency anemia during pregnancy. This study was used to investigate the efficacy of two new formulations of iron both in IV and oral…
- Trial name
- NCT07384663
- Testing
- Iron Carboxymaltose, Iron Polymaltose Complex
- Where
- Pakistan
- Volunteers
- 112 people
- Sponsor
- Dr Salaha Azam
Iron Deficiency Anemia Associated With Non-Dialysis Dependent Chronic Kidney Disease
Study to Evaluate the Safety and Tolerability of KRX-0502 (Ferric Citrate) in Children With Iron Deficiency Anemia Associated With Non-Dialysis Dependent Chronic Kidney Disease
This study will be conducted to evaluate the safety and tolerability of ferric citrate in pediatric participants with iron deficiency anemia (IDA) associated with non-dialysis dependent chronic kidney disease (NDD-CKD).
- Trial name
- NCT04649411
- Testing
- ferric citrate, standard of care
- Sponsor
- Keryx Biopharmaceuticals
Iron Deficiency Anemia, Iron Overload
Iron Supplementation and Side Effects
The objective of this study is to examine patient-reported gastrointestinal side effects, as well as iron status indicators, inflammatory markers and oxidative stress following administration of ferrous sulfate and iron-enriched…
- Trial name
- NCT04018300
- Testing
- Ferrous sulfate, Aspiron
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Anemia, Iron Deficiency, Ulcerative Colitis
Sucrosomial Iron vs. Oral Iron Sulfate for the Treatment of Iron Deficiency Anemia in Patients With Ulcerative Colitis
The aim of the study is to compare the tolerability and efficacy of Sucrosomial Iron to Oral Iron Therapy in a randomized controlled trial for the treatment of Iron Deficiency Anemia in Ulcerative Colitis patients.
- Trial name
- NCT05225545
- Testing
- Sucrosomial Iron, Oral Iron
- Where
- Lebanon
- Volunteers
- 30 people
- Sponsor
- American University of Beirut Medical Center
Fatigue, Low Mood
A Study to Evaluate the Effects of a Beef Liver Supplement on Energy, Mood, and Mental Clarity
This is a randomized, triple-blind, placebo-controlled clinical trial evaluating the effects of the Ancestral Supplements Grass Fed Beef Liver oral supplement on energy, mood, and mental clarity over 12 weeks.
- Conditions
- Fatigue, Low Mood, Mental Clarity, Iron Deficiency
- Trial name
- NCT07892911
- Testing
- Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ancestral Supplements, LLC
Iron-deficiency
Measuring Dietary Iron Absorption From Edible Insects and Assessing the Effect of Chitin Content on Iron Bioavailability (Study 2)
Due to the growing world population, there is a need to develop viable ecological and nutritional alternatives to animal food products.
- Trial name
- Sustironable2 (NCT05328141)
- Testing
- Bread and butter, X.gideon, X.gideon with ascorbic acid
- Where
- Switzerland
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron-deficiency
Prebiotic GOS and Lactoferrin With Iron Supplements
The ultimate goal of this research is to develop a means to safely administer iron supplements to infants in settings with a high infection burden.
- Trial name
- NCT03866837
- Testing
- Galacto-oligosaccharides, Bovine lactoferrin, Multiple micronutrient powders with 5 mg iron
- Where
- 2 sites in Kenya, Switzerland
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Columbia University
Iron Deficiency Anemia
Maintenance of Multivitamin Supplements After Sleeve Gastrectomy
A prospective randomized study of patients undergoing a laparoscopic sleeve gastrectomy was performed. Patients were randomized into 2 groups: those patients receiving the multivitamin supplement during 3 months (Group 1), and…
- Trial name
- NCT02620137
- Testing
- Multicentrum® (Pfizer, Spain) 3 months, Multicentrum® (Pfizer, Spain) 12 months
- Volunteers
- 80 people
- Sponsor
- Hospital General Universitario Elche
Anemia, Iron-Deficiency
Efficacy of a Preoperative Anaemia Clinic in Patients Undergoing Elective Abdominal Surgery
Efficacy of a preoperative anaemia clinic in patients undergoing elective abdominal surgery diagnosed with iron deficieny anaemia
- Trial name
- NCT05628896
- Where
- Denmark
- Volunteers
- 764 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Iron Deficiency Anemia
Ferrous Acetyl-Aspartate Casein Formulation Evaluation Over Ferrous Sulfate in Iron Deficiency Anemia
The scope of this study is to compare the efficacy of the new oral formulation of Fe-ASP to oral ferrous sulfate in patients with iron deficiency anemia (IDA) for the restoration of decreased circulating Hb.
- Trial name
- ACCESS (NCT03524651)
- Testing
- Ferrous Sulfate, Fe-ASP
- Where
- 3 sites in Greece
- Volunteers
- 60 people
- Sponsor
- Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.
Iron-deficiency
Iron Absorption From Encapsulated Iron Sulphate in Microspheres
Food fortification has shown to be efficacious to alleviate the burden of micronutrient deficiencies. Ensuring the bioavailability of iron and maintaining the sensory quality and stability of the fortified food and other added…
- Trial name
- NCT03332602
- Testing
- free FeSO4, free FeSO4 and empty microspheres, free FeSO4 and hylauronic acid
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency Anemia in Preterm Neaonates
Liposomal Iron Versus Ferrous Iron Supplementation for Early Prophylaxis of Iron Deficiency Anemia in Preterm Neonates
Iron prophylaxis will be initiated at age of 2-3 weeks at a dose of 3mg/kg/day. Standard care group: will receive ferrous iron (Enrich oral drops(50mg/ml), one drop per kilogram of body weight daily.
- Trial name
- NCT07667205
- Testing
- Daily oral ferrous ion, Daily oral liposomal iron, Oral liposomal iron every other day
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Iron Deficiency Without Anemia
Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses: an Experimental Study in Iron-deficient Women
Serum ferritin is a key indicator of body iron stores and is widely used in monitoring iron status. However, oral iron doses can acutely elevate SF levels, potentially biasing assessments of iron stores during supplementation.
- Trial name
- INFER 2 (NCT06851130)
- Testing
- ferrous sulfate 80 mg, ferrous sulfate 160 mg
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Swiss Federal Institute of Technology
Heart Failure With Reduced Ejection Fraction (HFrEF), Hospitalization
Intravenous Iron Sucrose for Acute Decompensated Heart Failure Patients With Reduced Ejection Fraction and Iron Deficiency
Iron deficiency (ID) affects about 25% of the global population, presenting with symptoms of fatigue, weakness, and impaired cognitive function.
- Conditions
- Heart Failure With Reduced Ejection Fraction (HFrEF), Hospitalization, Iron Deficiency
- Trial name
- IronSucroseHF (NCT06703411)
- Testing
- Iron Sucrose IV, Standard Medical Therapy
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Cheng-Hsin General Hospital
Obesity, Bariatric Surgery
Effectiveness of a Modified Cost-Effective Dietary Plan in Promoting Weight Loss and Preservation of Lean Body Mass in Patients After Bariatric Surgery
This study will see if a low-cost dietary plan, based on the standard dietary guidelines of the American Society for Metabolic and Bariatric Surgery (ASMBS) and using locally available foods, can help patients lose weight and…
- Conditions
- Obesity, Bariatric Surgery, Nutritional Status, Body Composition
- Trial name
- NCT07111767
- Testing
- Low-Cost Post-Bariatric Diet, Standard High-cost Post-Bariatric Diet
- Where
- Pakistan
- Volunteers
- 122 people
- Sponsor
- Khyber Teaching Hospital