Clinical trials: Anemia in Children
Iron Deficiency, Iron Deficiency Anemia
Effect of Iron Fortified Wheat Flour on Cognition and Iron Status in Indian School Children
This study is designed to evaluate the efficacy of NaFeEDTA-fortified whole wheat flour in improving cognition, hemoglobin, iron status and total body iron among school children in urban Bangalore.
- Conditions
- Iron Deficiency, Iron Deficiency Anemia, Cognition
- Trial name
- NCT00741143
- Testing
- Fortification of wheat flour with NaFeEdta
- Where
- India
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- St. John's Research Institute
Stunting, Anemia
Effectiveness Study During the First 1,000 Days in Kenya
Malnutrition is a public health problem in Kenya, with 26% of children underfive years of age stunted, and 26% of pre-school children, 26% of women of reproductive age and 42% of pregnant women being anaemic, respectively.
- Conditions
- Stunting, Anemia, Micronutrient Deficiency
- Trial name
- NCT03558464
- Testing
- Intervention (integrated package), Control
- Where
- Kenya
- Volunteers
- 1,199 people, healthy volunteers welcome
- Sponsor
- Fabian Rohner
Hookworm
Study to Test Whether Shoes Protect Children Against Hookworm Infection on Pemba Island, Zanzibar
Small association studies have hypothesised that shoes protect against hookworm infection. The purpose of this pragmatic study was determine, under field conditions, whether school-age children on Pemba Island, Zanzibar, would…
- Trial name
- SKIP (NCT01869127)
- Testing
- Shoes
- Where
- Tanzania
- Volunteers
- 1,056 people, healthy volunteers welcome
- Sponsor
- Bird, Christopher
Sickle Cell Anemia
Longitudinal Changes in Exercise Capacity in Children and Young Adults With Sickle Cell Anemia
The purpose of this study is to use comprehensive exercise testing to examine longitudinal changes in exercise capacity over a 2 year period in children and young adults with sickle cell anemia.
- Trial name
- NCT01558076
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Malaria,Falciparum, Anemia in Children
Comparing Chemoprevention Drugs for School-based Malaria Control
This is an individually randomized, controlled, single blind three arm clinical trial of malaria chemoprevention strategies Arm 1: Intermittent preventive treatment with dihydroartemisinin-piperaquine (IPT-DP).
- Trial name
- NCT05980156
- Testing
- Dihydroartemisinin-Piperaquine, Chloroquine, Sulfadoxine pyrimethamine
- Where
- Malawi
- Volunteers
- 646 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Undernutrition
Effectiveness of Small-Quantity vs Medium-Quantity Lipid-Based Nutrient Supplements for Prevention of Undernutrition in Young Children
Nutrition is essential for a child's growth, brain development, and protection from disease. While breastmilk provides the best nutrition for young infants, children older than six months may not get all the nutrients they need…
- Trial name
- NCT07451951
- Testing
- Medium-quantity lipid-based nutrient supplement (MQ-LNS), Small-quantity lipid-based nutrient supplement (SQ-LNS)
- Where
- 2 sites in Pakistan
- Volunteers
- 1,568 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Underweight, Stunting
Evaluation Research of the Nutrition Interventions in the INHP II Areas of CARE India
This study is designed to evaluate the effectiveness of CARE India's Integrated Nutrition and Health Program (INHP II) to reduce malnutrition among children 0-23 months of age.
- Conditions
- Underweight, Stunting, Wasting, Anemia
- Trial name
- NCT00198835
- Testing
- Maternal nutrition and infant feeding advice
- Where
- India
- Volunteers
- 17,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Cognitive Change, Beta-Thalassemia
Assessment of Cognitive Function, Fatigue and Health Related Quality of Life in Children With Beta Thalassemia
This study aims to: Assess the cognitive function in children with beta thalassemia Evaluate the fatigue in beta thalassemic children Assess the health related quality of life measures in children with beta thalassemia.
- Conditions
- Cognitive Change, Beta-Thalassemia, Fatigue, Quality of Life
- Trial name
- NCT05469230
- Where
- Egypt
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sickle Cell Anemia
Carbon Monoxide Monitor for the Measurement of End-Tidal Carbon Monoxide Levels in Children With or Without Hemolysis
People who have Sickle Cell Anemia (HbSS) produce red blood cells with shorter lifespans. These red blood cells breakdown faster, and this is called hemolysis.
- Trial name
- NCT01848691
- Testing
- Measurement of carbon monoxide level in exhaled breath
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ashutosh Lal
Healthy Participants, Non-anemic Children
Ferrous Fumarate and Ferric Pyrophosphate as Food Fortificants in Developing Countries
Iron fortification of foods is usually considered the most cost-effective approach to prevent iron deficiency. However, iron is the most difficult mineral to add to foods.
- Conditions
- Healthy Participants, Non-anemic Children, Helicobacter Pylori Infection
- Trial name
- NCT00867867
- Testing
- Ferrous fumarate, Ferric pyrophosphate
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Anemia, Undernutrition
Maternal Nutrition Interventions in Uttar Pradesh, India
Maternal nutrition has been a long-standing concern of health authorities globally and in India. Despite the availability of proven, affordable interventions, and progressive policies and program platforms such as Maternal…
- Conditions
- Anemia, Undernutrition, Underweight, Stunting
- Trial name
- NCT03378141
- Testing
- Maternal Nutrition Behavior change
- Where
- United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Anemia, Iron-Deficiency
Distribution of Fortified Yoghurt in Senegal to Decrease Children's Anemia and Improve Milk Supply
The study on dairy value chains that will be conducted in Northern Senegal tests whether a health-related product (micro-fortified yogurt) targeted to children can be provided through the logistics of an existing value chain, and…
- Trial name
- NCT02079961
- Testing
- Micronutrient-fortified yoghurt, BCC
- Where
- Senegal
- Volunteers
- 471 people, healthy volunteers welcome
- Sponsor
- Agnes LePort
Underweight, Stunted Growth
Effects of Multiple-micronutrients Supplementation on Growth and Iron Status of Indigenous Children in Malaysia
Child undernutrition is largely attributed to inadequate nutrition including micronutrient deficiency. Undernutrition is prevalent among indigenous children as compared to the general population.
- Conditions
- Underweight, Stunted Growth, Wasting, Anemia
- Trial name
- NCT04561635
- Testing
- Multiple-micronutrients supplement
- Where
- Malaysia
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Anaemia
Safe and Efficacious Iron for Children in Kenya
This study will determine whether the haemoglobin response to daily home fortification for 30 days with 3mg iron as NaFeEDTA is non-inferior to 12.5 mg iron as encapsulated ferrous fumarate.
- Trial name
- SEICK (NCT02073149)
- Testing
- Low-dose iron as NaFeEDTA, Conventional dose iron as ferrous salt
- Where
- Kenya
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Anemia
Etiology of Anemia Among Preschool Children in Ethiopia
This study aims to determine the etiology of anemia among preschool children in selected regions of Ethiopia. The study is a longitudinal observational study to assess the determinant factors of anemia in two different seasons.
- Trial name
- NCT05626647
- Where
- Ethiopia
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Malaria
Impact of School-based Delivery of Long Lasting Insecticide Nets
Insecticide-treated nets (ITNs), and more recently long lasting insecticide nets (LLINs), have been shown to effectively protect those groups most biologically vulnerable to the burden of malaria across Africa.
- Trial name
- NCT00878397
- Testing
- School-based delivery of long lasting insecticide nets
- Where
- Kenya
- Volunteers
- 5,113 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Iron-deficiency
Stable Iron Isotope Method in HIV+ and HIV- Children
The objective of this study is to compare HIV infected children to uninfected children regarding 1) quantifying iron absorption from iron fortified maize porridge, lipid-based food supplements and oral iron supplements, and 2)…
- Trial name
- NCT03572010
- Testing
- FeFum fortified maize test meal, FeSO4 fortified LNS, FeSO4 supplement
- Where
- South Africa
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Anemia, Iron Deficiency Anemia
Improving Iron Status of Children: Potential of Amaranth
Introduction: Iron deficiency anaemia remains a significant public health challenge. Localized food based approaches may offer a large opportunity to improve lives and address the widespread micronutrient deficiencies such as…
- Trial name
- NCT01224535
- Testing
- Maize and Amaranth
- Where
- Kenya
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Iron Deficiency, Vitamin A Deficiency
Nutritional Status and Bouillon Use in Northern Ghana
This pilot aims to generate data that are critical for informing the design of a planned, more detailed study to evaluate the effect of multiple micronutrient (MN)-fortified bouillon cube on biomarkers of nutrient status of women…
- Conditions
- Iron Deficiency, Vitamin A Deficiency, Vitamin B 12 Deficiency, Folate Deficiency
- Trial name
- NCT04632771
- Testing
- N/A (observational study)
- Where
- Ghana
- Volunteers
- 995 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Weight Gain, Anemia, Iron Deficiency
Egg Intervention During Pregnancy in Indonesia
The study consists of two arms: 1) intervention group using eggs as supplementary food given from 2nd trimester of pregnancy to birth, and 2) observational group of pregnant mothers.
- Conditions
- Weight Gain, Anemia, Iron Deficiency, Birth Weight, Birth Length
- Trial name
- PRECODE (NCT04694235)
- Testing
- Egg intervention
- Where
- Indonesia
- Volunteers
- 702 people, healthy volunteers welcome
- Sponsor
- SEAMEO Regional Centre for Food and Nutrition