Clinical trials: Anesthesia, Conduction
Carotid Stenosis, Carotid Artery Diseases
Cerebral Oximetry During Awake Carotid Endarterectomy
Surgery to remove plaque from the carotid artery in the neck requires the artery to be clamped for a period of time. In some patients this reduces blood flow to the brain enough to cause temporary symptoms, and a temporary…
- Conditions
- Carotid Stenosis, Carotid Artery Diseases, Brain Ischemia, Carotid Endarterectomy
- Trial name
- COACE (NCT07816081)
- Testing
- Masked continuous cerebral oximetry, Standardised awake neurological test, Serial cognitive assessment
- Where
- Vietnam
- Volunteers
- 150 people
- Sponsor
- Nguyen Toan Thang
Arthroplasty Replacement, Knee, Anesthesia Conduction
Migration Rate for Continuous Adductor Canal Block Catheters After Primary Total Knee Arthroplasty Surgery: a Comparison Between Two Insertion Techniques
Continuous adductor canal block (CACB) is becoming increasingly popular for providing postoperative analgesia following knee arthroplasties.
- Trial name
- ISAFExOOPS (NCT07681622)
- Testing
- ISAFE technique for adductor canal catheter insertion, OOPS technique
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Anesthesia, Conduction, Brachial Plexus Blockade
Comparison of Sympathetic Blockade Duration in Brachial Plexus Blocks Performed by Different Methods
This prospective comparative study will evaluate the sympathetic effects of ultrasound-guided infraclavicular versus supraclavicular brachial plexus blocks in adults undergoing upper-extremity surgery.
- Conditions
- Anesthesia, Conduction, Brachial Plexus Blockade, Sympathetic Blockade
- Trial name
- NCT07326436
- Testing
- Supraclavicular brachial plexus block, Infraclavicular brachial plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bozyaka Training and Research Hospital
Conduction Abnormalities, Paravertebral Anesthesia
Influence of Thoracic Paravertebral Block on Atrioventricular Conduction
The aim of the study is to assess the changes in electrical activity of heart atria and in atrioventricular conduction induced by anaesthetic thoracic paravertebral blockade, depending on site on which blockade was performed.
- Trial name
- NCT06833086
- Testing
- Paravertebral block (ropivacaine) left, Paravertebral block (ropivacaine) right
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Gdansk
Anesthesia, Conduction
Thermal-Imaging Comparison of Nerve Blocks for Bilateral Mastectomy
This is a one-armed trial of two regional anesthesia (peripheral nerve block) techniques to provide postoperative analgesia after bilateral mastectomy.
- Trial name
- NCT04928794
- Testing
- Erector Spinae Plane Block, Paravertebral Block
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of New Mexico
Coronary Artery Bypass, Anesthesia, Conduction
Effect of Transversus Thoracic Muscle Plane Block (TTMP) on Analgesia
In this prospective and controlled study, the investigators investigated the effect of transversus thoracic muscle plane block (TTMP) on analgesia in patients who undergo coronary artery bypass graft (CABG) surgery with median…
- Conditions
- Coronary Artery Bypass, Anesthesia, Conduction, Nerve Block, Pain, Postoperative
- Trial name
- NCT06601530
- Testing
- Transversus Thoracic Muscle Plane Block, Tramadol
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Istanbul University - Cerrahpasa
Drug Interactions, Anesthesia, Conduction
Interaction of Sevoflurane Propofol and Remifentanil in Anesthesia for Laparoscopic Surgery
Recently a new model for the interaction of sevoflurane propofol and remifentanil was developed. The potency of any combination of the three drugs is defined as probability that a subject tolerates laryngoscopy without movement…
- Trial name
- SPRV (NCT02457442)
- Testing
- Propofol and Remifentanil, Sevoflurane and Remifentanil, SPR 1
- Where
- Switzerland
- Volunteers
- 172 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Tourniquets, Anesthesia, Conduction
Femoral Artery Block for Reduction of Tourniquet Induced Hypertension
A randomised controlled trial to assess the impact of femoral artery block on the incidence of tourniquet hypertension in patients receiving cruciate ligament surgery with > 30 minutes of tourniquet under combined anaesthesia…
- Conditions
- Tourniquets, Anesthesia, Conduction, Anesthetics, Local, Hypertension
- Trial name
- NCT05954689
- Testing
- Femoral artery block
- Volunteers
- 50 people
- Sponsor
- Hospital da Luz, Portugal
Anesthesia, Conduction, Arthroplasty, Replacement, Knee
Inter-fascial Plane Between the SArtorius Muscle and FEmoral Artery (ISAFE)
Total knee arthroplasty (TKA) is a frequent performed surgery. Adequate pain management is an important feature. Analgesic duration of single shot nerve blocks is limited to no more than 24h.
- Trial name
- ISAFE (NCT05313269)
- Testing
- ISAFE technique for adductor canal catheter insertion, Conventional technique for adductor canal catheter insertion
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Anesthesia, Conduction
Lateral Cutaneous Nerve and PENG Blocks Versus Suprainguinal Fascia Iliaca Block in Post-op Analgesia of Hip Fractures
Postoperative pain in hip fractures is challenging and requires adequate management. Peripheral nerve blocks are already known as superior than systemic analgesia in this scenario, but the best analgesic regional technique is…
- Trial name
- NCT05749367
- Testing
- Ropivacaine + saline solution, Saline solution + Ropivacaine
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Federal University of Minas Gerais
Thoracic Surgery, Analgesics, Opioid
Opioid Free Anesthesia in Thoracic Surgery
Proper assessment of pain and adequate analgesia in thoracic surgery is a challenging issue for medical practitioners. Basic aspects of thoracic anaesthesia are general anesthesia, intubation with double lumen tube and separation…
- Conditions
- Thoracic Surgery, Analgesics, Opioid, Anesthesia, Conduction
- Trial name
- NCT04355468
- Testing
- Opioid Anesthesia, Opioid Free Anaesthesia
- Where
- Poland
- Volunteers
- 66 people
- Sponsor
- Medical University of Silesia
Anesthesia, Conduction, Pain, Postoperative
Combined PENG and LFCN Block for Total Hip Arthroplasty
A clinical trial investigating the effect of a combined locoregional anesthesia technique on the postoperative analgesia outcomes after a total hip arthroplasty. A PENG block will be used in combination with a LFCN block.
- Conditions
- Anesthesia, Conduction, Pain, Postoperative, Arthroplasty, Replacement, Hip
- Trial name
- NCT04996290
- Testing
- PENG + LFCN block, Ropivacaine injection
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Antwerp
Anesthesia Conduction, Upper Extremity Surgery
Comparison of Infraclavicular And Supraclavicular Block
Ultrasound-guided brachial plexus blocks are used successfully for upper extremity surgeries. In this randomized prospective single-blind study, ASA I-II patients aged 18-65 years undergoing hand, wrist, and forearm surgery will…
- Conditions
- Anesthesia Conduction, Upper Extremity Surgery, Pain, Postoperative, Anesthesia and Analgesia
- Trial name
- NCT04784104
- Testing
- Bupivacaine HCl 0.5% Injectable Solution, Prilocaine HCl 2% Injectable solution, Adrenaline amp. 0.5 mg
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Bozyaka Training and Research Hospital
Arthroplasty, Replacement, Knee, Pain, Postoperative
Comparison Of Femoral Block And Middle Adductor Canal Block In Patients With Knee Arthroplasty
Femoral and adductor nerve blocks with ultrasonography(USG) guidance are used effectively and efficiently in post-operative pain management in lower extremity surgical procedures.
- Conditions
- Arthroplasty, Replacement, Knee, Pain, Postoperative, Anesthesia and Analgesia, Anesthesia, Conduction
- Trial name
- NCT04768764
- Testing
- Ultrasound Guided Middle Adductor Canal Block, Ultrasound Guided Femoral Nerve Block., Bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Bozyaka Training and Research Hospital
Anesthesia, Conduction, Ropivacaine
Minimal Effective Concentration (EC90) of Ropivacaine
Prospective up and down sequential evaluation of the minimal effective concentration of perineural ropivacaine for 90% success in axillary brachial plexus block with the injection of intravenous dexamethasone or saline placebo…
- Conditions
- Anesthesia, Conduction, Ropivacaine, Dexamethasone, Axillary Brachial Plexus Block
- Trial name
- AxiRopiDexa (NCT03688269)
- Testing
- Intravenous dexamethasone, Intravenous saline, Perineural ropivacaine
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Arthroplasty, Replacement, Knee, Anesthesia, Conduction
Adductor Canal Vs Adductor Canal Plus SPANK Block for Postoperative Pain in Knee Arthroplasty Surgery
This study will prospectively investigate the efficacy of Adductor canal block with periarticular infiltration Vs Adductor canal block, Periarticluar infiltration and Sensory posterior articular nerve of the knee block in…
- Conditions
- Arthroplasty, Replacement, Knee, Anesthesia, Conduction, Acute Pain
- Trial name
- NCT04290442
- Testing
- adductor canal block, SPANK, Ropivacaine
- Where
- United States
- Sponsor
- Bruce Ben-David
Hormones, Anesthesia, Conduction
The Impact of Regional Anaesthesia on Hormone Levels in Thoracic Surgery.
Basic aspects of thoracic anaesthesia are general anesthesia often combined with regional anesthesia, intubation with double lumen tube and separation of lung ventilation.
- Conditions
- Hormones, Anesthesia, Conduction, Thoracic Surgical Procedure
- Trial name
- NCT04414488
- Testing
- Thoracic paravertebral block (ThPVB)
- Where
- Poland
- Volunteers
- 119 people
- Sponsor
- Medical University of Silesia
Appendectomy, Laparoscopy
TAP Block or Wound Infiltration for Laparoscopic Pediatric Appendectomy: a Pilot Study
Effectiveness of the TAP block compared to wound infiltration in controlling pain after laparoscopic appendectomy in children
- Conditions
- Appendectomy, Laparoscopy, Anesthesia, Conduction, Child, Preschool
- Trial name
- NCT04294537
- Testing
- TAP Block, LIA local infiltration, General anesthesia
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Ospedale di Circolo - Fondazione Macchi
Arthroplasty, Replacement, Knee, Anesthesia, Conduction
Femoral Triangle Block: Early Mobilization and Postoperative Analgesia After Total Knee Arthroplasty
The objective of this trial is to compare the efficacy of three different nerve blocks as an analgesic option after total knee arthroplasty (TKA), based on muscle strength, mobilization and pain.
- Conditions
- Arthroplasty, Replacement, Knee, Anesthesia, Conduction, Pain, Postoperative, Ultrasonography, Interventional
- Trial name
- NCT03518450
- Testing
- Apex Femoral Triangle Block, Femoral Nerve Block, Adductor Canal Block
- Where
- Spain
- Volunteers
- 78 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Anesthesia, Conduction
RCT Impact of Serratus Intercostal Plane Block in Video Assisted Thoracic Surgery
Rationale Video Assisted Thoracic Surgery (VATS) is known to be a moderate painful procedure. There are many ways to manage postoperative pain following this kind of surgery.
- Trial name
- NCT03449329
- Testing
- SIP
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- AZ Sint-Jan AV