Clinical trials: Anesthesia, Epidural
Postoperative Pain
Comparison of Paravertebral Versus Epidural Block for Post-thoracotomy Pain Control
This is a randomized, assessor-blinded, non-inferiority clinical trial comparing continuous thoracic paravertebral block (BPV) versus continuous thoracic epidural block (BPD) for postoperative pain control in adult patients…
- Trial name
- NCT07763249
- Testing
- Continuous Thoracic Paravertebral Block, Continuous Thoracic Epidural Block
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Ceserean Section, Obstetric Quality of Recovery
Anesthetic Technique and Quality of Recovery After Cesarean Delivery
The goal of this prospective observational study is to evaluate whether the type of neuraxial anesthesia is associated with postoperative quality of recovery in adult women undergoing cesarean delivery.
- Conditions
- Ceserean Section, Obstetric Quality of Recovery, Neuraxial Anesthesia
- Trial name
- NCT07896733
- Testing
- Spinal anesthesia (heavy bupivacaine), epidural anesthesia, combine spinal epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Marmara University
Pain
Ultrasound-Guided Technique for Thoracic Epidural Insertion
Thoracic epidural analgesia and anesthesia are effective in improving the quality of intraoperative and postoperative pain relief during thoracic and abdominal surgical procedures.
- Trial name
- NCT01449214
- Testing
- Ultrasound, Landmarking
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Parturients, Childbirth
Comparison Of The Analgesia Obtained By Infiltration For The Joinings Of Episiotomies (Liropep)
Lateral episiotomy is a current care practiced with childbirth room. One of the problems encountered with this surgical act is the residual pain on perineal scar level.
- Trial name
- LiRoPep (NCT00727935)
- Testing
- Lidocaïne, Ropivacaïne
- Where
- France
- Volunteers
- 165 people
- Sponsor
- University Hospital, Angers
Labor Pain
CSE for Labour Analgesia: A Comparison of Two Intrathecal Regimens
Analgesia in labour is not readily available in many parts of Sub-Saharan Africa. The overall cost of Epidural services in terms of human personnel and financial implication makes this inaccessible to many women in labour.
- Trial name
- SSS (NCT03117595)
- Testing
- Bupivacaine-fentanyl, Bupivacaine-fentanyl morphine
- Where
- Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sarah Beckley
Lung Cancer
Postoperative Pain After Single Port, Two Ports and Three Ports VATS Lobectomy
This single-center, prospective, randomized controlled trial was designed to assess and compare the postoperative pain after VATS lobectomy performed though one, two and three incisions.
- Trial name
- NCT03228056
- Testing
- pain intensity measured in VAS scale
- Where
- 2 sites in Poland
- Volunteers
- 90 people
- Sponsor
- Pulmonary Hospital Zakopane
Postoperative Pain, Pediatric Anesthesia Department
Pediatric Postoperative Pain Management
This prospective, observational study evaluates the effectiveness of perioperative pain management strategies in pediatric patients undergoing elective surgical procedures.
- Conditions
- Postoperative Pain, Pediatric Anesthesia Department, Regional Anaesthesia, Pain Scale
- Trial name
- NCT07392827
- Where
- Turkey (Türkiye)
- Volunteers
- 219 people
- Sponsor
- Hacettepe University
Epidural Anesthesia, Infection
The Effect of Combined General-epidural vs General Anaesthesia on Postoperative Gastrointestinal Surgery
Sixty neonates and infants will be enrolled and randomised into two groups of n=30 each . For their surgical procedures, one group general (GA) anaesthesia the second group will receive a combined general and epidural anaesthesia…
- Conditions
- Epidural Anesthesia, Infection, Infant, Newborn, Diseases
- Trial name
- NCT03056261
- Testing
- Combined general and epidural, General anaesthesia
- Volunteers
- 60 people
- Sponsor
- Bnai Zion Medical Center
Epidural Catheterization
Ultrasound Predictors of Difficulty in Performing Epidural Anesthesia for Labor in Pregnant Patients.
This is a prospective observational study conducted at the University Hospital of Padua. The goal is to identify ultrasound markers that can help predict whether placing an epidural catheter during labor will be difficult.
- Trial name
- NCT07056166
- Testing
- epidural catheter, spine ultrasonography
- Where
- Italy
- Volunteers
- 563 people
- Sponsor
- University of Padova
Early Confirmation of Epidural Catheterization
Early Detection of Epidural Onset by Temperature Change
Traditionally, placement of the epidural catheter is based on hand feel of passing through the ligamentum flavum as well as "loss of resistance" while injecting the air through the needle.
- Trial name
- NCT02838056
- Testing
- epidural injection
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Medical University WanFang Hospital
Cesarean Section Complications
Effect of Three Weight-adjusted Vasopressors for Elective Cesarean Delivery
This study compared the effects of prophylactic infusion of metaraminol, phenylephrine and norepinephrine adjusted according to body weight on fetal acid-base balance and maternal hemodynamics.
- Trial name
- NCT04991662
- Testing
- metaraminol, Phenylephrine, Norepinephrine
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Xuzhou Medical University
Postpartum Urinary Retention
Effect of Voiding Position (Standing in the Shower vs. Sitting) on Post- Void Residual Urine Volume (PVR) After Removal of Urinary Catheter in Women Following Vaginal Delivery With Epidural Analgesia: A Double- Blind Randomized Controlled Trial
Postpartum urinary retention is a common complication after childbirth, with a higher risk for women who undergo vaginal delivery with epidural analgesia.
- Trial name
- NCT07893119
- Testing
- Standing in the shower, Sitting on the toilet
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Labor Pain
Intermittent Automated Devices for Labor Analgesia in Emilia Romagna
The study aims to determine whether the use of automated intermittent devices for labor analgesia could prevent the increase of instrumental deliveries, with same analgesia.
- Trial name
- PA-RER (NCT02710877)
- Testing
- Programmed Intermittent bolus, Manual epidural bolus, Levobupivacaine
- Where
- 3 sites in Italy
- Volunteers
- 671 people
- Sponsor
- University of Modena and Reggio Emilia
Coxarthrosis, Pain, Postoperative
Lumbar ESPB in Hip Replacement Surgery
In this study, continuous erector spinae plane block (ESPB) will be compared to continuous epidural analgesia in patients undergoing elective hip replacement surgery.
- Conditions
- Coxarthrosis, Pain, Postoperative, Pain, Acute, Pain, Chronic
- Trial name
- ESPB_HIP (NCT06282666)
- Testing
- Spinal anesthesia, lumbar erector spinae plane block, Epidural analgesia
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Lublin
Anesthesia
Chloroprocaine for Continuous Epidural Analgesia in Neonates and Infants
This a study to retrospectively review our experience with the use of chloroprocaine for postoperative epidural infusions in neonates and infants.
- Trial name
- NCT02207855
- Testing
- Chloroprocaine
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Joseph D. Tobias
Pain Management, Pain, Postoperative
Preperitoneal Analgesia Versus Epidural Analgesia After Open Pancreaticoduodenectomy
This is a prospective randomized open-label noninferiority trial that compares thoracic epidural analgesia and continuous preperitoneal analgesia after open pancreaticoduodenectomy.
- Trial name
- Pain (NCT04375826)
- Testing
- Epidural patient controlled analgesia, Preperitoneal analgesia and IV-PCA
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Seoul National University Hospital
Analgesia, Epidural, Instrumental Delivery
The Randomised Epidural Analgesia in Term Delivering Women Trial (TREAT)
The objective of the study: to assess the impact of a proactive policy of offering EA at the start of labour as compared to a restrictive policy or care as usual.
- Conditions
- Analgesia, Epidural, Instrumental Delivery, Maternal Outcome, Neonatal Outcome
- Trial name
- TREAT (NCT01261689)
- Testing
- Ropivacaine/ Sufentanil according to local hospital protocol, Care-as usual pain treatment
- Where
- 2 sites in Netherlands
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Anesthesia, Obstetrical, Analgesia, Epidural
Epidural Analgesia During Labour
Randomized single blind trial based on comparing the way the local anesthetic is dosificated during labour. The pain control is evaluated and compared with both dosage techniques (PCEA vs PIEB)using levobupivacaine and fentanyl.
- Trial name
- PIEBvsPCEA (NCT03133091)
- Testing
- PIEB: Patient Intermittent Epidural Boluses, PCEA: Patient Controlled Epidural Analgesia
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital del Rio Hortega
Complications; Cesarean Section
Use of Intrathecal Fentanyl and Development of Hyperalgesia in Patients Undergoing Elective Cesarean
Opioid analgesic drugs are the main treatment of patients during anesthesia. Although highly effective, their use is not without problems. One is the increasing requirement of these address the same nociceptive stimulus.
- Trial name
- NCT02387060
- Testing
- H-Bupivacaine, Fentanyl
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Obesity/therapy
Rhomboid Intercostal Block with Subserratus Plane Block in Bariatric Surgery
Standard analgesic techniques such as patient-controlled analgesia (PCA) and continuous epidural analgesia (CEA) are effective but associated with considerable side effects, including nausea, hypotension, and respiratory…
- Trial name
- NCT06729515
- Testing
- PCA, CEA, RISS
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Xiaguang Duan