Clinical trials: Anesthesia, General
Breast Cancer
Effect of Midazolam Premedication Before Induction on the Functional Recovery After General Anesthesia in the Patients Undergoing Breast Surgery Due to Breast Cancer
Normally, higher levels of preoperational stress or anxiety affect behavior and recovery after the operation. Moreover, patients undergoing mastectomy are usually young women, and this demographic is known to experience higher…
- Trial name
- NCT01945476
- Testing
- midazolam premedication
- Where
- South Korea
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Nociceptive Pain, Pain, Postoperative
Guiding Opioid Administration by Nociception Level Index (NOL) in Patients With Regional Anesthesia
General anesthesia consists of a combination of hypnotic drugs to achieve unconsciousness and opioid analgesics to ensure antinociception.
- Conditions
- Nociceptive Pain, Pain, Postoperative, Analgesia, Postoperative, Anesthesia Recovery Period
- Trial name
- NORA (NCT06905340)
- Testing
- NOL (Nociception Level Index), Control (Standard treatment)
- Where
- Germany
- Volunteers
- 240 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Extravasation, Vein Injury
Color Doppler and Peripheral Venous Catheters
Objective: To evaluate color Doppler flow ultrasound compared to standard clinical techniques, to detect the correct position of peripheral intravenous catheters in adult surgical patients.
- Trial name
- NCT03889678
- Testing
- Color flow doppler
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Augusta University
General Anesthesia
Heated Circuit on Sore Throat
This investigation is planned to compare the incidence and severity of postoperative sore throat according to the use of heated breathing circuit in patients undergoing endotracheal intubation for general anesthesia.
- Trial name
- NCT03693417
- Testing
- Heated circuit on, Heated circuit off
- Volunteers
- 92 people
- Sponsor
- Keimyung University Dongsan Medical Center
Continuous Positive Airway Pressure, Hypoxia
Positive Pressure at Induction of Anesthesia in Children
SCENARIO: Hypoxemia is one of the most common adverse events during the induction of general anesthesia and may culminate with more serious complications such as cardiac arrest and death.
- Conditions
- Continuous Positive Airway Pressure, Hypoxia, General Anesthesia
- Trial name
- NCT03432390
- Testing
- Continuous Positive Airway Pressure, Open system ventilation
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Post Operative Nausea and Vomiting
the Effect of Three Different Analgesic Techniques on the Incidence of Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) is a distressing adverse effect that may result in postoperative complications including bleeding, wound dehiscence, aspiration pneumonitis, as well as fluid and electrolyte imbalances…
- Trial name
- NCT03313479
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Anesthesia; Reaction, Children, Only
Effect of Anesthesia Induction on Cerebral Hemodynamic in Children
General anesthesia induces hemodynamic changes, notably a reduction of arterial blood pressure going up to 30%, that may impact cerebral perfusion and oxygenation.The purpose of this study is to assess the impact of anesthesia on…
- Trial name
- PEDICACHE (NCT04581213)
- Testing
- General anesthesia
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- St. Justine's Hospital
General Anesthesia
Comparison of LMA-Fastrach and I-gel for Blind Tracheal Intubation.
The investigators aim to compare two different types of supraglottic devices for tracheal intubation in patients undergoing elective surgery under general anesthesia.
- Trial name
- NCT01007370
- Testing
- Tracheal intubation
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Vitamin D Deficiency
Preoperative Vitamin D Levels and Respiratory Complications of General Anesthesia
Vitamin D deficiency is a commonly observed health problem in the world. With a role in many chronic diseases and especially lung diseases, the importance of vitamin D deficiency in anesthesia management is increased.
- Trial name
- VitaminD (NCT03342651)
- Testing
- Vitamin D
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Ordu University
Cerebral Perfusion, Cerebral Oxygenation
Evaluation of Cerebral Oxygenation During Orthopedic Surgeries Performed in the Beach Chair Position Under General Anesthesia
The goal of this observational study is to determine the correlation between cerebral oxygenation values measured by near-infrared spectroscopy (NIRS) and other routine monitoring parameters in patients placed in the semi-sitting…
- Conditions
- Cerebral Perfusion, Cerebral Oxygenation, Hemodynamic Monitoring, Semi-sitting Position
- Trial name
- NCT07270341
- Testing
- Near-Infrared Spectroscopy (NIRS) Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Akdeniz University
Quality of Life, Pain, Postoperative
Quality of Recovery After General or Spinal Anesthesia for Inguinal Hernia Repair
Different anesthetic techniques have been proposed for carrying out Inguinal hernia repair, including local anesthesia, regional and general.
- Conditions
- Quality of Life, Pain, Postoperative, Personal Satisfaction, Postoperative Complication
- Trial name
- NCT02696122
- Testing
- Local Group, Spinal anesthesia
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Laryngeal Disease, Pharyngeal Diseases
Comparison of Remimazolam and Propofol for Recovery of Ambulatory Upper Airway Surgery
The purpose of this study is to compare the effects of remimazolam and propofol on postoperative recovery time, complications, and safety in patients undergoing ambulatory upper airway surgery under general anesthesia.
- Conditions
- Laryngeal Disease, Pharyngeal Diseases, Oral Cavity Disease, Nasal Disease
- Trial name
- NCT06507202
- Testing
- Remimazolam, Propofol
- Where
- South Korea
- Volunteers
- 116 people
- Sponsor
- Chung-Ang University Gwangmyeong Hospital
Pediatric General Anesthesia With Endotracheal Tube
Ultrasound Study of the Airway to Predict Endotracheal Tube Size in Anesthetized Pediatric Patients
The purpose of this study is to determine whether ultrasound study of the airway to predict endotracheal tube size in anesthetized pediatric patients better than the tube size formula
- Trial name
- NCT02321956
- Testing
- Ultrasound
- Where
- Thailand
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Analgesia, Anesthesia
Analgesic Depth Evaluation During General Anesthesia With Dexmedetomidine-remifentanil Infusion. A Pilot Study
The aim of this study is to verify the feasibility of an evaluation of the depth of analgesia during an opioid sparing anesthesia (OSA) carried out with continuous infusion of dexmedetomidine in addition to general multimodal…
- Trial name
- NCT05785273
- Testing
- Pupillometer
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Università degli Studi di Brescia
Anesthesia, Anesthesia Recovery Period
Effect of Epidural Anesthesia and Analgesia on Quality of Recovery After Unilateral Nephrectomy.
Different modality of anesthesia and analgesia could influence a postoperative quality of recovery (QoR). This study is exploring early QoR after unilateral nephrectomy in the two groups of anesthesia.
- Conditions
- Anesthesia, Anesthesia Recovery Period, Nephrectomy, Patient Satisfaction
- Trial name
- QoR (NCT04521556)
- Testing
- Epidural anesthesia with light general anesthesia, Postoperative epidural analgesia, General anesthesia
- Where
- Croatia
- Volunteers
- 80 people
- Sponsor
- University Hospital of Split
Hypotension, Anesthesia
The Hypotensive Effect of Propofol: an Observational Study
Hypotension is a recognized frequent complication of induction of anesthesia. The intent of this research is to determine the incidence of hypotension in patients receiving anesthetic induction with propofol.
- Trial name
- NCT01508351
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Milton S. Hershey Medical Center
General Anesthesia, Supraglottic Airway Device
The Accuracy of the Performance and Placement Test for Predicting Supraglottic Airway Device (SAD) Position in the Hypopharynx as Confirmed With Video Laryngoscopy
The supraglottic airway device (SAD) is currently widely used in patients undergoing general anaesthesia as a method of securing the airway.
- Conditions
- General Anesthesia, Supraglottic Airway Device, Laryngeal Mask Airway
- Trial name
- NCT03643029
- Testing
- Video-laryngoscopy following SAD insertion
- Volunteers
- 50 people
- Sponsor
- University of Malaya
Laryngeal Disease
Randomized Controlled Trial:High-flow Oxygen Therapy and Tracheal Intubation for Laryngeal Microsurgery
Over time, the accumulation of carbon dioxide reduces the pressure gradient for the alveolar transfer of oxygen, limiting the successful duration of apneic oxygenation.
- Trial name
- NIRS_ORL (NCT05400642)
- Testing
- THRIVE, mechanical ventilation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Postoperative Pain, Acute Pain
Analgesic Equivalence of NSAIDs and Tramadol in Acute Postoperative Pain Following Minimally Invasive Surgery
This pilot randomised controlled trial compared the analgesic equivalence of three intravenous premedication regimens - tramadol 150 mg, ketorolac 60 mg, and diclofenac 150 mg - in adult patients undergoing elective minimally…
- Trial name
- NCT07500454
- Testing
- Tramadol, Ketorolac, Diclofenac
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- ISSSTE Hospital Regional "Gral. Ignacio Zaragoza"
Prostatic Neoplasm
The Effects of Method of Anaesthesia on the Safety and Effectiveness of Radical Retropubic Prostatectomy
Prostate cancer is one of the most commonly diagnosed neoplasm in men worldwide. The gold standard of therapy is radical prostatectomy, a wide surgical excision of the neoplasm and can be performed either open, laparoscopic or…
- Trial name
- NCT05566405
- Testing
- General Anaesthesia, Combined (Epidural and Spinal) Anaesthesia, Open Retropubic Radical Prostatectomy
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Sismanoglio General Hospital